International Journal of Current Pharmaceutical Research最新文献_第2页

A CROSS-SECTIONAL SURVEY OF KNOWLEDGE, ATTITUDE AND PRACTICE OF P-DRUG IN A TEACHING HOSPITAL. 在一家教学医院开展的关于 P-药物的知识、态度和实践的横断面调查。

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5013

H. D. P., SWETHA K.

{"title":"A CROSS-SECTIONAL SURVEY OF KNOWLEDGE, ATTITUDE AND PRACTICE OF P-DRUG IN A TEACHING HOSPITAL.","authors":"H. D. P., SWETHA K.","doi":"10.22159/ijcpr.2024v16i4.5013","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5013","url":null,"abstract":"Objective: Postgraduates represent the future generation of practitioners and there aren't many studies on the P-drug idea that specifically target them. Hence, we have taken up this study to assess the knowledge, attitude and practice of P-drug among the postgraduates.\u0000Methods: A prospective observational study with a cross-sectional design was conducted at a Tertiary Care Teaching Hospital. Participants' responses were gathered using a pre-validated questionnaire. It evaluated participants' understanding of the P-drug concept, attitudes about P-drugs as treatments for illnesses, and actual P-drug prescribing behaviours. Statistical Package for Social Sciences (SPSS) software version 26 was used to analyze data after compiling data in the Excel sheet.\u0000Results: Out of 230 participants, majority were the females (67.8%). 63% of participants were aware of the “rational use of medicines,” and around 57% of them knew about the P-drug concept. 44.8% were aware of STEP criteria which is applied to select P-drug. Only 66 were practising with the P-drug list and the majority of them opined that teaching programmes are necessary to create awareness about the practice of the P-drug.\u0000Conclusion: It is encouraging that the current study's findings point to reasonable drug usage rather than irrational use. The P-drug idea is a useful instrument for enhancing medical treatment and encouraging ethical drug usage. Furthermore, additional research has to be done to determine how P-drug use affects patient outcomes and healthcare expenditures over the long run.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HOSPITAL ADMINISTRATION IN A PERIPHERAL REMOTE LOCATION HOSPITAL: A EVIDENCE BASED STUDY 边远地区医院的医院管理：实证研究

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5045

D. Pitale, S. N. Jadhav

{"title":"HOSPITAL ADMINISTRATION IN A PERIPHERAL REMOTE LOCATION HOSPITAL: A EVIDENCE BASED STUDY","authors":"D. Pitale, S. N. Jadhav","doi":"10.22159/ijcpr.2024v16i4.5045","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5045","url":null,"abstract":"Objective: The organisation of the human society has undergone a unique transition throughout the last decades. With the rise of ever growing technologization and disruptive innovations, populations also demand more social and environmental initiatives from firms and governments. In 2015, the United Nations (UN) member states agreed upon a 2030 Agenda for Sustainable Development. Developing a sustainable UHC is decisive to ensure better economic prospects and social equality across socioeconomic classes. This can be achieved by lowering the barriers to access health services to the most vulnerable groups and improve mortality and disability rates in the potential workforce.\u0000Methods: The present study was conducted in a remote location defence hospital catering to the health care needs of serving personnel of Indian armed forces and civilians residing in this peripheral area. The basic specialties including Obstetrics, paediatrics, medicine and general surgery are provided at this centre 24*7 by the dedicated medical officers of Indian Armed forces.\u0000Results: Sustainability of care continuously evolves towards becoming a major factor for public healthcare organisations, and more accountability will likely be demanded of managers to deliver on each aspect of its triple bottom line. This study shows that prevention and patient empowerment both carry great potential to attain this objective.\u0000Conclusion: It is necessary to set priorities and act according to available resources and organisational vision. The central threats to sustainability of public health care welfare systems in peripheral hospitals identified, namely the ageing population and rise in chronic diseases. UHC at a meso and micro level, could provide a much better rationale for scholars to evaluate the need for change, and contribute to draft more inclusive sustainable strategies.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ANTHROPOMETRIC STUDY OF LEFT EXTERNAL EAR: A CROSS-SECTIONAL STUDY IN MEDICAL STUDENTS OF UDAIPUR, RAJASTHAN 左外耳的人体测量学研究：对拉贾斯坦邦乌达布尔医学生的横断面研究

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5052

Shrivastava Bhavana, Acharya Sunita, Bharambe Vaishaly Kishore, Medatwal Bhupesh

{"title":"ANTHROPOMETRIC STUDY OF LEFT EXTERNAL EAR: A CROSS-SECTIONAL STUDY IN MEDICAL STUDENTS OF UDAIPUR, RAJASTHAN","authors":"Shrivastava Bhavana, Acharya Sunita, Bharambe Vaishaly Kishore, Medatwal Bhupesh","doi":"10.22159/ijcpr.2024v16i4.5052","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5052","url":null,"abstract":"Objective: The human ears are specific to an individual because the auricle is also a distinctive feature of a person like other identification features so it is used in various areas of science like forensic medicine, anthropology, and biology. The ear lobule is the last part of the auricle to develop.\u0000Methods: This study was carried out among 100 students (50 Male and 50 Female) with age range from 18 to 25 years. The study was conducted in the Department of Anatomy, Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India.\u0000Results: Total ear length and ear width were significantly higher in male than female (p value<0.0001) in this study. Lobule length and lobule width of left ear were compared by independent t-test, it was found nonsignificant (p value 0.5706) and significantly higher in male than female (p 0.0017) respectively. The mean value of lobule index of left ear was found significant with higher value in male while the mean value of ear index of left ear was found nonsignificant.\u0000Conclusion: Results according to genders who participated in the study where all dimensions (total ear length, ear width, lobule width and lobule index) were higher in male as compared to the female subjects. Although there was no significant difference observed in lobule length and ear index of left ear of male and female subjects.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COMPLICATIONS OF MECHANICAL VENTILATION IN CHILDREN UP TO 12 Y OF AGE 12 岁以下儿童机械通气的并发症

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.4096

Vijay Laxmi Sharma, D. Phirke, Shraddha Khalate

{"title":"COMPLICATIONS OF MECHANICAL VENTILATION IN CHILDREN UP TO 12 Y OF AGE","authors":"Vijay Laxmi Sharma, D. Phirke, Shraddha Khalate","doi":"10.22159/ijcpr.2024v16i4.4096","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.4096","url":null,"abstract":"Objective: Mechanical ventilation has been proven to be lifesaving and has significantly reduced mortality in the pediatric population. Despite its life-saving advantages, mechanical ventilation is associated with complications. The study aimed to assess the complications of mechanical ventilation in children up to 12 y of age admitted to the intensive care unit.\u0000Methods: The present descriptive, observational, cross-sectional study was conducted on 165 children aged between 0 to 12 y, who were mechanically ventilated for>48 h. Patients were observed daily until the desired result was achieved and were checked to look for complications or negative effects of mechanical ventilation.\u0000Results: The majority of subjects belonged to<1 mo of age (77.58%) whereas the maximum number of patients were male (64.24%). In 77.58% of patients, the indication for mechanical ventilation was respiratory failure. The duration of ventilation in 62.43% of patients was>7 d. A total of n=62 (37.58%) patients had ventilator-associated complications. The most common complication was ventilator-associated pneumonia (n=30, 48.38%). The mean hospital stay was found to be 22.88±7.96 d. Whereas the mean hospital stay in patients without complications was significantly less compared to patients with complications (18.57±10.09 d vs 27.19±5.83 d, P=0.00015). The mortality rate was found to be 47.27%.\u0000Conclusion: Respiratory cause was the most common indication for mechanical ventilation. The most common complication was ventilator-associated pneumonia. The subjects with complications had prolonged hospital stays.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

STUDY OF PREVALENCE OF SCRUB TYPHUS IN ACUTE FEBRILE ILLNESS IN A TERTIARY CARE HOSPITAL, VISAKHAPATNAM 研究维萨卡帕特南一家三级护理医院急性发热性疾病中恙虫病的流行情况

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5046

T. M. S. S. S. Vani

{"title":"STUDY OF PREVALENCE OF SCRUB TYPHUS IN ACUTE FEBRILE ILLNESS IN A TERTIARY CARE HOSPITAL, VISAKHAPATNAM","authors":"T. M. S. S. S. Vani","doi":"10.22159/ijcpr.2024v16i4.5046","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5046","url":null,"abstract":"Objective: Re-emergent cases of rickettsial disease, the scrub typhus is seen prevalent in cases of acute febrile illness. The objective of this study was to study the magnitude and prevalence of scrub typhus in a tertiary care hospital.\u0000Methods: This prospective study was carried on for a period of one year from February 2023 to February 2024. Inpatients between the age group of 16 to 25 y with a triad of fever for more than 5 d of onset with or without an eschar, headache, myalgia and abnormal haematological and biochemical parameters were included in the study. IgM ELISA for scrub typhus was performed.\u0000Results: Prevalence of scrub typhus in this study was 9.4% with higher male preponderance of 69.4% in 18 y age group 28.6%. Positive cases were recorded higher during post monsoon season of September 18.9%. Co-infection with dengue and malaria observed in 2 cases and ARDS was the complication in 3 cases. No mortality in this study.\u0000Conclusion: It is important to get familiar with the clinical and diagnostic laboratory findings of scrub typhus so as to differentiate it from other aetiologies of acute febrile illness.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IN SILICO DOCKING STUDY OF HERBAL COMPOSITION AND DEVELOPMENT OF MOUTH DISSOLVING TABLETS FOR COMMON RESPIRATORY DISEASES THEREOF 草药成分的硅对接研究及其常见呼吸道疾病口腔溶解片的开发

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5010

Ankita Chandwani, K. Modi, Kaushik Shah, Mamta Shah

引用次数: 0

A STUDY TO EVALUATE THE TYPE AND CAUSE OF BLINDNESS/LOW VISION IN APPLICATIONS FOR BLINDNESS CERTIFICATE PRESENTING IN CHAMBA DISTRICT OF HIMACHAL PRADESH 对喜马偕尔邦 Chamba 地区申请失明证书的失明/低视力类型和原因进行评估的研究

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.4091

Smriti Sharma, Shaloo Negi, Aditya Kashyap

{"title":"A STUDY TO EVALUATE THE TYPE AND CAUSE OF BLINDNESS/LOW VISION IN APPLICATIONS FOR BLINDNESS CERTIFICATE PRESENTING IN CHAMBA DISTRICT OF HIMACHAL PRADESH","authors":"Smriti Sharma, Shaloo Negi, Aditya Kashyap","doi":"10.22159/ijcpr.2024v16i4.4091","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.4091","url":null,"abstract":"Objective: This study aims to assess the prevalence, causes, and socio-economic impacts of visual impairment in the Chamba District of Himachal Pradesh, India. It seeks to identify the major factors contributing to visual disability and the role of literacy and employment status in influencing the lives of the visually impaired.\u0000Methods: A cross-sectional, hospital-based study was conducted over a period of one year, enrolling patients from the outpatient department of ophthalmology who were applying for visual disability certification. The study utilized a randomized sampling method and a semi-structured interview along with an examination form for data collection. Ethical approval was obtained, and the study adhered to ICMR and Helsinki Declaration guidelines. Participants underwent comprehensive ophthalmic evaluations, and data were analyzed using SPSS version 17.0.\u0000Results: Among the 270 participants evaluated, a higher prevalence of visual impairment was observed in males (n=149) compared to females (n=121), particularly within the age group of 21-40 y. The leading causes of visual disability included Corneal Opacity (16.25%), Retinitis Pigmentosa (15.83%), and Congenital Malformation (14.17%). Furthermore, literacy played a crucial role in employment opportunities, with 75.83% of the literate participants being employed, indicating a significant impact on the socio-economic status.\u0000Conclusion: The study highlights the multifaceted nature of visual impairment in the Chamba District, emphasizing the need for integrated public health strategies to address the identified challenges. Enhancing preventive measures, improving access to healthcare, and supporting rehabilitation services are essential steps towards mitigating the burden of visual impairment.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PREVALENCE OF POLYCYSTIC OVARIAN SYNDROME AMONG YOUNG WOMEN WHO ATTENDED TERTIARY CARE HOSPITAL, VISAKHAPATNAM 在维萨卡帕特南市三级医院就诊的年轻女性中多囊卵巢综合征的患病率

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5026

Ksk Divya, Bnv Mounisha, R. V. Sowmya

{"title":"PREVALENCE OF POLYCYSTIC OVARIAN SYNDROME AMONG YOUNG WOMEN WHO ATTENDED TERTIARY CARE HOSPITAL, VISAKHAPATNAM","authors":"Ksk Divya, Bnv Mounisha, R. V. Sowmya","doi":"10.22159/ijcpr.2024v16i4.5026","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5026","url":null,"abstract":"Objective: The present study aimed to determine the prevalence of PCOS among young adults attended to medical OP in a Tertiary care teaching hospital.\u0000Materials: It is a retrospective study conducted in a Tertiary care teaching hospital, Visakhapatnam using existing records in the Department of Obstetrics and Gynaecology. The study was conducted from July 2021 to July 2023. The study population includes young adults of age in between 18-30 y. PCOS was defined by Rotterdam's criteria having presence of any two of the three features. Hormonal assays were conducted using immunoradiometric assay for TSH, LH, FSH.\u0000Results: Majority of the PCOS cases 39% were reported in the age group of 26-30 Y. Among the 100 cases reported, the majority of them are reported with menstrual irregularity 62%. However, it was identified from the results that the mean values of cholesterol and triglycerides levels are quite higher suggested hyperlipidemia. The hormonal levels of TSH, LH and FSH were normal.\u0000Conclusion: Although the overall frequency of PCOS is low and evaluating PCOS in young adults can be difficult, the condition is becoming more common at this age. Changes in lifestyle are essential at this age to avoid long-term metabolic and reproductive issues.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TREATMENT OUTCOME OF TUBERCULOSIS CASES AMONG PAEDIATRIC PATIENTS IN WESTERN RAJASTHAN 西拉贾斯坦邦儿科结核病人的治疗结果

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5021

Yogesh Yadav, Jyoti Choudhary, Mohammed Nasir Khan

引用次数: 0

APPLICATION OF VALIDATED RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF METAXALONE AND DICLOFENAC POTASSIUM IN PLASMA 应用有效的 RP-HPLC 方法同时测定血浆中的美他沙酮和双氯芬酸钾

International Journal of Current Pharmaceutical Research Pub Date : 2024-07-15 DOI: 10.22159/ijcpr.2024v16i4.5039

D. Ramesh, M. Habibuddin

{"title":"APPLICATION OF VALIDATED RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF METAXALONE AND DICLOFENAC POTASSIUM IN PLASMA","authors":"D. Ramesh, M. Habibuddin","doi":"10.22159/ijcpr.2024v16i4.5039","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5039","url":null,"abstract":"Objective: The present investigation demonstrates a simple, sensitive and accurate high-pressure liquid chromatographic (HPLC) method for simultaneous determination of metaxalone (MTX) and Diclofenac potassium (DIC) in plasma by using Valsartan (VSN) as internal standard.\u0000Methods: The chromatographic separation was achieved within 10 min by using methanol: potassium dihydrogen phosphate buffer pH 4.5 adjusted with orthophosphoric acid (60:40) as mobile phase on Altima Grace Smart C-18 column (5μ; 250×4.6 mm) at flow rate of 1.0 ml/min with injection volume 25µl. The drug was extracted from plasma by liquid-liquid extraction using methanol as a solvent. The retention times of drugs (MTX and DIC) and internal standard were found to be 5.83, 9.65 and 11.79 min, respectively. This method was validated as per United States Food and Drug Administration (US-FDA) guidelines.\u0000Results: The results of the validation parameters were found to be within the acceptance limits. The method was linear in the concentration range from 25-1000 ng/ml (r2= 0.9998) and the extraction recovery was found to be 77.06% for MTX and 78.37% for DIC. The lower limit of quantification was found to be 25ng/ml and the stability of recovered samples at different conditions were found to be more than 95% for both the drugs.\u0000Conclusion: The developed method possesses good selectivity specificity, there was no interference found in the plasma blanks at retention times of MTX and DIC. We found good correlation between the peak area and concentration of the drug under prescribed conditions. Furthermore, the method can also be used to estimate the pharmacokinetic parameters of MTX and DIC simultaneously.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0