Gabriele M Iacona, Serge Harb, Venkatesh Krishnamurthi, James J Yun
{"title":"Intracaval Leiomyoma with Intracardiac Extension.","authors":"Gabriele M Iacona, Serge Harb, Venkatesh Krishnamurthi, James J Yun","doi":"10.1055/s-0041-1736442","DOIUrl":"https://doi.org/10.1055/s-0041-1736442","url":null,"abstract":"<p><p>The objective of this study was to explain step by step how to achieve a complete resection of an intravascular leiomyoma. A 48-year-old woman was referred to our institution with progressive dyspnea on exertion, lightheadedness, and previous history of total abdominal hysterectomy and bilateral salpingo-oophorectomy for a uterine leiomyoma echocardiography, computed tomography, and magnetic resonance imaging of the heart and abdomen/pelvis were performed and an intracaval mass with extension into the right heart and pulmonary artery was identified. After multidisciplinary review, a single-stage sternotomy-laparotomy procedure on cardiopulmonary bypass (with beating heart, mild hypothermia, and no deep hypothermic circulatory arrest) ensured complete resection of a giant intravenous leiomyoma (IVL). Multidisciplinary approach, multimodality imaging, and single-stage sternotomy-laparotomy procedure on cardiopulmonary bypass (with heart beating and mild hypothermia) ensure complete resection of IVL.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 2","pages":"136-139"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191695/pdf/10-1055-s-0041-1736442.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9499845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dedy Pratama, Fajar Satria Rahmaditya, Alexander Jayadi Utama, Raden Suhartono, Akhmadu Muradi
{"title":"Risk Factors of Asymptomatic Carotid Artery Disease in Geriatric Evaluated Using Carotid Intima-Media Thickness (IMT) Measurement, the First Indonesian Population Study.","authors":"Dedy Pratama, Fajar Satria Rahmaditya, Alexander Jayadi Utama, Raden Suhartono, Akhmadu Muradi","doi":"10.1055/s-0042-1750040","DOIUrl":"https://doi.org/10.1055/s-0042-1750040","url":null,"abstract":"<p><p>Carotid artery disease in geriatric is one of the important etiologies of stroke, which topped the cause of mortality in Indonesia. Specific prevention should be done as early as asymptomatic disease occurred. Initial assessment can be performed using ultrasound by measuring the intima-media thickness (IMT) of carotid artery, which can evaluate earlier progression of the atherosclerosis process. Unfortunately, we do not have risk factors categorization that show us which geriatric population fall under high-risk stratification to be screened. Study was done to Indonesian geriatric population. Asymptomatic carotid disease was tested positive if IMT was > 0.9 mm without any previous neurological symptoms. Correlation of the result was statistically tested with risk factors of atherosclerotic process, such as sex, body mass index, presence of hypertension, diabetes mellitus, and hypercholesterolemia. Study obtained 104 subjects and showed the prevalence of asymptomatic carotid disease was 37.5%. Two risk factors: diabetes mellitus and hypercholesterolemia were statistically significant ( <i>p</i> = 0.01) with odds ratio (OR) 3.56 (1.31-9.64, 95% confidence interval [CI]) and OR 2.85 (1.25-6.51, CI 95%), respectively. Logistic regression showed the risk was 69.2% by having two of these comorbidities, 47.2 or 42.5% if diabetes mellitus or hypercholesterolemia was present. As diabetes mellitus and hypercholesterolemia were proved to be significant risk factors for asymptomatic carotid artery disease, we recommend performing ultrasound screening to measure carotid artery IMT for geriatric population who had diabetes mellitus and/or hypercholesterolemia for asymptomatic carotid artery disease to be diagnosed and further treated.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 2","pages":"95-99"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191689/pdf/10-1055-s-0042-1750040.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9707302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Frozen Elephant Trunk Technique to Treat Extensive Thoracic Aortic Mural Thrombus.","authors":"Dmitri S Panfilov, Boris N Kozlov","doi":"10.1055/s-0041-1740916","DOIUrl":"https://doi.org/10.1055/s-0041-1740916","url":null,"abstract":"<p><p>We describe a case report of a 63-year-old man who presented with chronic left-hand weakness and the absence of a pulse in the left arm. Thoracoabdominal computed tomography (CT) revealed an extensive thoracic aortic mural thrombus. Initial anticoagulation therapy did not provide a positive result, so the patient was referred for surgery. Hybrid aortic arch surgery using the frozen elephant trunk technique was performed with excellent early outcomes. A CT performed in the early postoperative period showed that the thrombus was completely excluded from the aortic lumen by the hybrid graft. No thrombus dislodgment was detected. No thrombus recurrence was observed during 19 months of follow-up.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 2","pages":"140-142"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191685/pdf/10-1055-s-0041-1740916.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9551569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surya Dharma, Iwan Dakota, Hananto Andriantoro, Isman Firdaus, Citra P Anandira, Basuni Radi
{"title":"Interhospital Transfer versus Direct Admission in Patients with Acute ST-Segment Elevation Myocardial Infarction.","authors":"Surya Dharma, Iwan Dakota, Hananto Andriantoro, Isman Firdaus, Citra P Anandira, Basuni Radi","doi":"10.1055/s-0040-1714686","DOIUrl":"https://doi.org/10.1055/s-0040-1714686","url":null,"abstract":"<p><p>There is concern whether patients with ST-segment elevation myocardial infarction (STEMI) who admitted to a percutaneous coronary intervention (PCI) center from interhospital transfer is associated with longer reperfusion time compared with direct admission. We evaluated the reperfusion delays in patients with STEMI who admitted to a primary PCI center through interhospital transfer or direct admission. We retrospectively analyzed 6,494 consecutive STEMI patients admitted between 2011 and 2019. Compared with direct admission ( <i>n</i> = 4,121; 63%), interhospital transferred patients ( <i>n</i> = 2,373) were younger (55 ± 10 vs. 56 ± 10 years, <i>p</i> < 0.001), had similar gender (85.6 vs. 86% male, <i>p</i> = 0.67), greater proportion of off-hour admission (65.2 vs. 48.3%, <i>p</i> < 0.001), less diabetes mellitus (28 vs. 30.8%, <i>p</i> = 0.019), and received more primary PCI (70.5 vs. 48.7%, <i>p</i> < 0.001). Interhospital transferred patients who received primary PCI ( <i>n</i> = 3,677) or fibrinolytic ( <i>n</i> = 238) had longer symptom-to-PCI center admission time (median, 360 vs. 300 minutes, <i>p</i> < 0.001), shorter door-to-device (DTD) time for primary PCI (median, 74 vs. 87 minutes, <i>p</i> < 0.001), and longer total ischemic time (median, 465 vs. 414 minutes, <i>p</i> < 0.001). Logistic regression in interhospital transferred patients showed that delay in door-in-to-door-out (DI-DO) time at the first hospital was strongly associated with prolonged total ischemic time (adjusted odds ratio = 3.92; 95% confidence interval: 3.06-5.04, <i>p</i> < 0.001). This study suggests that although interhospital transferred patients received more primary PCI with shorter DTD time, interhospital transfer creates longer total ischemic time that associates with the delay in DI-DO time at the first hospital that should be improved.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 2","pages":"121-127"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0040-1714686","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9551571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chaozer Er, Navin Kuthiah, Thofique Adamjee, Jam Chin Tay
{"title":"Venous Thromboembolism Risk Assessment and Thromboprophylaxis Practice in General Medical Patients Requiring Admissions to General Wards: A Singapore's Perspective, Part 2.","authors":"Chaozer Er, Navin Kuthiah, Thofique Adamjee, Jam Chin Tay","doi":"10.1055/s-0041-1730448","DOIUrl":"https://doi.org/10.1055/s-0041-1730448","url":null,"abstract":"on","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 2","pages":"146-152"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191693/pdf/10-1055-s-0041-1730448.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9499840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparisons of Patients Living Alone versus Living with Others in Acute Coronary Syndrome.","authors":"Yusaku Shibata, Nobuaki Kobayashi, Akihiro Shirakabe, Yasushi Miyauchi, Kuniya Asai","doi":"10.1055/s-0043-1767697","DOIUrl":"10.1055/s-0043-1767697","url":null,"abstract":"<p><p>We aimed to examine the relationship of living arrangements (i.e., living alone or living with others) with background, clinical severity, preintervention culprit lesion plaque morphology, and clinical outcomes in patients with acute coronary syndrome (ACS). Among 1,683 consecutive patients with ACS, we retrospectively compared patients living alone ( <i>n</i> = 318) versus living with others ( <i>n</i> = 1,362). Optical coherence tomography (OCT) findings, which are high-resolution intracoronary imaging devices, were analyzed in patients with preintervention OCT and compared between patients living alone ( <i>n</i> = 174) versus those living with others ( <i>n</i> = 665). Older (median; 69 vs. 67 y, <i>p</i> = 0.046) and female (31 vs. 17%, <i>p</i> < 0.001) patients more frequently lived alone. Frequency of achieving a time interval of 6 hours or less from ACS onset to admission was lower in patients living alone (56 vs. 63%, <i>p</i> = 0.022). Clinical presentation was more severe in patients living alone (Killip II/III/IV; 27 vs. 22%, <i>p</i> = 0.029). Plaque morphology evaluated by OCT was similar between groups (plaque rapture; 48 vs. 48%, <i>p</i> = 0.171). Kaplan-Meier analyses revealed higher rates of cardiac mortality during 2-year follow-up period in patients living alone [13.9 vs. 8.5%, hazard ratio (HR) 1.604, 95% confidence interval (CI) 1.112-2.313, <i>p</i> = 0.010]. After traditional cardiovascular risk factors and clinical severity upon admission had been adjusted, living alone was an independent predictor of cardiac mortality in ACS patients (HR 1.582, 95% CI 1.056-2.371, <i>p</i> = 0.026). Living alone was independently associated with 2-year cardiacmortality in ACS patients after adjusting for background and presentation and might be unrelated to the development of atherosclerosis.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 3","pages":"179-187"},"PeriodicalIF":0.6,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10352051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Iqbal, M. Febrianora, I. C. S. Putra, M. Pramudyo, C. Achmad
{"title":"Incidence of Myocarditis Associated with Diphtheria, Tetanus, and Pertussis Vaccine: A Rare Case Series","authors":"Mohammad Iqbal, M. Febrianora, I. C. S. Putra, M. Pramudyo, C. Achmad","doi":"10.1055/s-0043-1767740","DOIUrl":"https://doi.org/10.1055/s-0043-1767740","url":null,"abstract":"Abstract Myocarditis induced by diphtheria–tetanus–pertussis (DTP) vaccination is extremely rare, accounting for only two cases thus far. Hence, to supplement knowledge regarding its pathogenesis and treatment, we reported two cases of myocarditis associated with DTP vaccination in adults. Two patients (a 40-year-old female and a 43-year-old male) presented with mild symptoms and were hemodynamically stable. In both patients, the DTP vaccination was given 4 and 6 days before admission. Both patients had prolonged corrected QT interval (QTc), poor left ventricular function, and high troponin levels at admission. However, numerous ST segment depression was only noted in the first case. Bacteriology and virology study results were negative for any pathogen. No atherosclerotic lesions were observed by coronary angiography. Cardiac magnetic resonance imaging was only performed in the second case, which confirmed the diagnosis of myocarditis. Initial therapy was administered with a beta-blocker, angiotensin-converting enzyme inhibitor, and intravenous methylprednisolone. Nonetheless, in the first case, rapid clinical deterioration and sudden cardiac death occur within 3 days of hospitalization. Learn from the first case, a high-dose intravenous immunoglobulin (IVIG) treatment was initiated in the second case, which resulted in an improvement in left ventricular function and clinical symptoms, as well as a significant reduction in QTc interval and troponin levels. Rapid diagnostic testing and early recognition of the fulminant course is mandatory, allowing clinicians to aggressively treat the patient with high-dose intravenous immune globulin, thus obtaining a better outcome.","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47752066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Derek O Pipolo, Sara Guevara, Lana Vasiljevic, Andres E Di Pietrantonio, Walter Brennan, Humberto Asmus, Alexia McCann-Molmenti, Young Min Cho, Koichiro Shinozaki, Kei Hayashida, Yu Okuma, Muhammad Shoaib, Lance B Becker, Mary E Decker, Hermoon A Worku, Petra Majdak, Grace Donzelli, Akash Patel, Sherwin Davoud, Andres Vaca-Zorrilla, Sascha S Beutler, Ernesto P Molmenti, Santiago J Miyara
{"title":"Intracranial Hypertension following Acute Mesenteric Ischemia: A Case Study on the Multiple Compartment Syndrome.","authors":"Derek O Pipolo, Sara Guevara, Lana Vasiljevic, Andres E Di Pietrantonio, Walter Brennan, Humberto Asmus, Alexia McCann-Molmenti, Young Min Cho, Koichiro Shinozaki, Kei Hayashida, Yu Okuma, Muhammad Shoaib, Lance B Becker, Mary E Decker, Hermoon A Worku, Petra Majdak, Grace Donzelli, Akash Patel, Sherwin Davoud, Andres Vaca-Zorrilla, Sascha S Beutler, Ernesto P Molmenti, Santiago J Miyara","doi":"10.1055/s-0043-1763252","DOIUrl":"10.1055/s-0043-1763252","url":null,"abstract":"<p><p>In this case study, we describe a 25-year-old male who was admitted due to a severe traumatic brain injury, requiring invasive intracranial pressure monitoring. At 48 hours posttrauma, he developed intracranial hypertension refractory to medical treatment without tomographic changes in the brain. Subsequently, intra-abdominal hypertension and tomographic signs of abdominal surgical pathology were observed. An exploratory laparotomy was performed with an intraoperative diagnosis of acute mesenteric ischemia. After surgical intervention for the abdominal pathology, intracranial pressure was restored to physiological values with a favorable recovery of the patient. In this report, the relationship between intracranial pressure and intra-abdominal pressure is discussed, highlighting the delicate association between the brain, abdomen, and thorax. Measures should be taken to avoid increases in intra-abdominal pressure in neurocritical patients. When treating intracranial hypertension refractory to conventional measures, abdominal causes and multiple compartment syndrome must be considered. The cranial compartment has physiological interdependence with other body compartments, where one can be modified by variations from another, giving rise to the concept of multiple compartment syndrome. Understanding this relationship is fundamental for a comprehensive approach of the neurocritical patient. To the best of our knowledge, this is the first report of a comatose patient post-traumatic brain injury, who developed medically unresponsive intracranial hypertension secondary to acute mesenteric ischemia, in which surgical resolution of intra-abdominal pathology resulted in intracranial pressure normalization and restitutio ad integrum of neurological status.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 3","pages":"188-192"},"PeriodicalIF":0.6,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Infarct Size and Long-Term Clinical Outcomes of Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndrome Undergoing Coronary Artery Stenting: A Prospective Randomized Study.","authors":"Takayuki Yabe, Ryota Noike, Ryo Okubo, Hideo Amano, Takanori Ikeda","doi":"10.1055/s-0042-1746417","DOIUrl":"https://doi.org/10.1055/s-0042-1746417","url":null,"abstract":"<p><p>The antiplatelet drug prasugrel inhibits platelet aggregation early after oral administration. This study examined whether prasugrel is effective in inhibiting infarct size and can reduce the incidence of major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS). This study was a single-center, prospective, randomized pilot study. Among 80 ACS patients treated at our institution between August 2014 and September 2015, 76 ACS patients who underwent stenting and achieved thrombolysis in myocardial infarction flow grade 3 were assigned to receive aspirin plus prasugrel (prasugrel group; <i>n</i> = 37) or aspirin plus clopidogrel (clopidogrel group; <i>n</i> = 39). The primary endpoint was survival free of MACE. The secondary endpoint was the evaluation of infarct size defined as the area under the curve (AUC) of troponin I, calculated using the linear trapezoidal method. During follow-up (mean, 1262.4 ± 599.6 days), 14 patients showed MACE. No significant differences in CYP2C19 genotype were seen between groups. AUC of troponin I up to 72 hours after intervention tended to be smaller in the prasugrel group (1,927.1 ± 2,189.3 ng/mL) than in the clopidogrel group (3,186.0 ± 3,760.1 ng/mL, <i>p</i> = 0.08). Cumulative incidence of MACE was significantly higher in the clopidogrel group (log-rank test; <i>p</i> = 0.02). Compared with clopidogrel, prasugrel was associated with reduced infarct size and lower frequency of long-term outcomes among ACS patients undergoing stenting.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 1","pages":"56-65"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886453/pdf/10-1055-s-0042-1746417.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9836504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percutaneous Transluminal Angioplasty in Chronic Total Subclavian Venous Stenosis Using Coronary Guidewire: A Case Report.","authors":"Todung D A Silalahi, Christopher S Suwita","doi":"10.1055/s-0041-1735207","DOIUrl":"https://doi.org/10.1055/s-0041-1735207","url":null,"abstract":"<p><p>Arteriovenous fistula is the best permanent vascular access for hemodialysis (HD). However, in our country, HD catheter in jugular or subclavian vein is more commonly found because our patients prefer to hold HD until the complications are unbearable. The catheter increases risk of venous stenosis on site and in surrounding vessels, resulting in access loss. Percutaneous transluminal angioplasty (PTA), combined with stent deployment, can be utilized as main treatment for such stenosis in subclavian vein. This method dated back to two decades ago with high success rate. Nevertheless, reports or studies of angioplasty in total occlusion are scarce, mainly because of lower success rate and the need of smaller penetrating wire. We describe our experience in performing PTA and stent deployment using coronary wire to penetrate total occlusion in subclavian venous stenosis after vein cannulation. We hope that we can give an alternative technique to avoid surgery in such cases.</p>","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 1","pages":"66-70"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886449/pdf/10-1055-s-0041-1735207.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10643428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}