补充欧米茄-3 和心血管疾病风险的当前证据和未来方向

IF 0.5 Q4 PERIPHERAL VASCULAR DISEASE

International Journal of Angiology Pub Date : 2023-11-24 DOI:10.1055/s-0043-1777258

B. Dwiputra, Anwar Santoso, Budhi Setianto Purwowiyoto, B. Radi, B. Pandhita, Serlie Fatrin, A. M. Ambari

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引用次数: 0

摘要

摘要欧米伽-3 补充剂在心血管疾病二级预防中的作用备受争议。尽管多年来发表了大量临床试验，但欧米伽-3 在预防心血管疾病，尤其是冠心病方面的作用仍无定论。不过，最近使用较高剂量的欧米伽-3或高纯度的欧米伽-3酯类进行的临床试验显示出良好的效果，心血管死亡人数和心血管疾病发病率均有所下降。本综述旨在总结欧米伽-3预防心血管疾病的可能机制，以及欧米伽-3对心血管疾病益处的未来研究方向。

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Current Evidence and Future Directions of Omega-3 Supplementation and Cardiovascular Disease Risk

Abstract Omega-3 supplementation has a controversial role in the secondary prevention of cardiovascular diseases. Despite large clinical trials published over the years, the evidence of omega-3 in preventing cardiovascular diseases, especially coronary heart disease, is still inconclusive. However, recent clinical trials using higher dose of omega-3 or highly purified esters of omega-3 shows promising result, with reduction in cardiovascular death and incidence of cardiovascular disease. This review aims to summarize the possible mechanism of omega-3 in preventing cardiovascular disease and future directions of research regarding the benefit of omega-3 in cardiovascular disease.

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来源期刊

International Journal of Angiology PERIPHERAL VASCULAR DISEASE-

CiteScore

1.30

自引率

16.70%

发文量