Scandinavian cardiovascular journal : SCJ最新文献

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In-hospital outcomes after rotational atherectomy in patients with low ejection fraction. 低射血分数患者旋转动脉粥样硬化切除术后的住院结果。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2018-08-01 Epub Date: 2018-04-18 DOI: 10.1080/14017431.2018.1455988
Yusuke Watanabe, Toru Naganuma, Hiroyoshi Kawamoto, Hisaaki Ishiguro, Sunao Nakamura
{"title":"In-hospital outcomes after rotational atherectomy in patients with low ejection fraction.","authors":"Yusuke Watanabe,&nbsp;Toru Naganuma,&nbsp;Hiroyoshi Kawamoto,&nbsp;Hisaaki Ishiguro,&nbsp;Sunao Nakamura","doi":"10.1080/14017431.2018.1455988","DOIUrl":"https://doi.org/10.1080/14017431.2018.1455988","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated angiographic success and in-hospital outcomes of percutaneous coronary intervention (PCI) with rotational atherectomy (RA) in patients with low left ventricular ejection fraction (LVEF).</p><p><strong>Design: </strong>Between January 2010 and March 2014, 272 consecutive patients with heavily calcified lesions underwent elective PCI with RA. Of these, 33 patients had LVEF ≤35% (low LVEF group), whereas 237 patients had LVEF >35% (preserved LVEF group). The primary endpoint was angiographic success and in-hospital major adverse cardiac events (MACE). MACE included death from any cause, postprocedure onset MI, emergency coronary artery bypass grafting, and target vessel revascularization. The secondary endpoints were MACE and the components within 30days after PCI. The components of MACE were evaluated.</p><p><strong>Results: </strong>Angiographic success, defined as <30% residual stenosis with thrombolysis in myocardial infarction flow 3 at final angiography, was achieved in all patients without fatal complications. Intra-aortic ballon pumping (IABP) was used significantly more frequently in the low LVEF group compared with the preserved LVEF group (15.2% vs. 2.1%, p = .003). There were no significant differences between groups regarding in-hospital and clinical outcomes within 30 days following PCI.</p><p><strong>Conclusion: </strong>If medications and mechanical support were appropriately performed, the angiographic success rate and in-hospital MACE rate of PCI with RA in patients with low LVEF could be expected to have good outcomes similar to those for patients with preserved LVEF.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"177-182"},"PeriodicalIF":2.2,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/14017431.2018.1455988","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39965797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Clinical use of optical coherence tomography to identify angiographic silent stent thrombosis. 光学相干断层扫描鉴别血管造影无症状支架血栓的临床应用。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2014-06-01 DOI: 10.3109/14017431.2014.900185
Sonja E Steigen, Niels Ramsing Holm, Noreen Butt, Michael Maeng, Fumiyuki Otsuka, Renu Virmani, Elena Ladich, Terje K Steigen
{"title":"Clinical use of optical coherence tomography to identify angiographic silent stent thrombosis.","authors":"Sonja E Steigen,&nbsp;Niels Ramsing Holm,&nbsp;Noreen Butt,&nbsp;Michael Maeng,&nbsp;Fumiyuki Otsuka,&nbsp;Renu Virmani,&nbsp;Elena Ladich,&nbsp;Terje K Steigen","doi":"10.3109/14017431.2014.900185","DOIUrl":"https://doi.org/10.3109/14017431.2014.900185","url":null,"abstract":"<p><strong>Objectives: </strong>Patients previously treated with coronary stents may suffer an acute coronary syndrome (ACS) without any evidence of thrombus formation on coronary angiography (CAG). This may be due to partial, nonocclusive stent thrombosis with microembolization. In this paper, we illustrate possible mechanisms both with optical coherence tomography (OCT) and histology.</p><p><strong>Design: </strong>We present two cases with ACS from very late stent thrombosis who have been previously treated with first-generation drug-eluting stents (DES).</p><p><strong>Results: </strong>The first patient had ACS 15 months after DES implantation. The angiogram (CAG) was near normal with slight peri-stent contrast staining. OCT revealed abnormalities including thrombus not visible on CAG. These are findings that may explain the ACS. The second patient had subclinical episodes with chest pain after DES implantation. The patient died from stent thrombosis in a DES. Postmortem histological examination of the coronary arteries revealed stent struts with little or no neointimal coverage, persistent peri-strut fibrin deposition, inflammatory cells, malapposition, and small luminal platelet-rich thrombi. Old spotty myocardial infarctions were found in the supplied territory possibly caused by earlier episodes of embolizing thrombus.</p><p><strong>Conclusions: </strong>In patients with previous implanted DES presenting with ACS, OCT may detect abnormalities and thrombus formation not visible on CAG. Such findings may impact the treatment strategy in these patients.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"156-60"},"PeriodicalIF":2.2,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2014.900185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40288697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Adjustment of aortic annulus size during David re-implantation (how to do it). David再植入术中主动脉环大小的调整(如何做)。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2013-08-01 Epub Date: 2013-04-02 DOI: 10.3109/14017431.2013.779018
Jaroslav Benedik, Daniel Wendt, Mareike Perrey, Vivien Price, Heinz Jakob
{"title":"Adjustment of aortic annulus size during David re-implantation (how to do it).","authors":"Jaroslav Benedik,&nbsp;Daniel Wendt,&nbsp;Mareike Perrey,&nbsp;Vivien Price,&nbsp;Heinz Jakob","doi":"10.3109/14017431.2013.779018","DOIUrl":"https://doi.org/10.3109/14017431.2013.779018","url":null,"abstract":"<p><p>Stability of the aortic annulus is a key factor in achieving long-term durability of the aortic valve re-implantation. We propose a new method of sub-annular fixation of the root prosthesis, enabling post-procedural transesophageal echocardiography (TEE)-guided adjustment of the aortic annulus dimensions.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"245-6"},"PeriodicalIF":2.2,"publicationDate":"2013-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2013.779018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40237757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Avoidance of noninfectious sternal dehiscence: figure-of-8 wiring is superior to straight wire closure. 避免非传染性胸骨裂:8字线优于直线闭合。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2013-08-01 Epub Date: 2013-01-10 DOI: 10.3109/14017431.2012.761723
Sven M Almdahl, Per Halvorsen, Terje Veel, Stein E Rynning
{"title":"Avoidance of noninfectious sternal dehiscence: figure-of-8 wiring is superior to straight wire closure.","authors":"Sven M Almdahl,&nbsp;Per Halvorsen,&nbsp;Terje Veel,&nbsp;Stein E Rynning","doi":"10.3109/14017431.2012.761723","DOIUrl":"https://doi.org/10.3109/14017431.2012.761723","url":null,"abstract":"<p><strong>Objectives: </strong>Comparison of figure-of-8 wiring or simple straight-wiring technique assessed by the frequency of early noninfectious sternal dehiscence.</p><p><strong>Design: </strong>Observational register study with 7835 patients having sternal closure with figure-of-8 steel wires was compared with 2122 patients, where the sternotomy was closed by simple interrupted straight wires. The endpoint was the rate of early (within 30 days) sterile sternal dehiscence.</p><p><strong>Results: </strong>Fourteen patients (0.66%) with single wires and five patients (0.06%) with figure-of-8 wires underwent re-operation for nonmicrobial sternal disruption (p < 0.0001). The median time-point for re-intervention was 6 days for both groups. In more than 6000 patients, the sternotomy was closed with five figure-of-8 wires without dehiscence in any of them.</p><p><strong>Conclusion: </strong>In a large cohort of consecutive cardiac operations, it was found that sternal closure with figure-of-8 wires is better than closure with simple interrupted wires.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"247-50"},"PeriodicalIF":2.2,"publicationDate":"2013-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2012.761723","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40223434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Sevoflurane at 1 MAC provides optimal myocardial protection during off-pump CABG. 七氟醚在1 MAC时提供最佳的心肌保护。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2013-06-01 Epub Date: 2013-01-17 DOI: 10.3109/14017431.2012.760749
Jiang Wang, Hong Zheng, Chun-Ling Chen, Wei Lu, Yong-Qiang Zhang
{"title":"Sevoflurane at 1 MAC provides optimal myocardial protection during off-pump CABG.","authors":"Jiang Wang,&nbsp;Hong Zheng,&nbsp;Chun-Ling Chen,&nbsp;Wei Lu,&nbsp;Yong-Qiang Zhang","doi":"10.3109/14017431.2012.760749","DOIUrl":"https://doi.org/10.3109/14017431.2012.760749","url":null,"abstract":"<p><strong>Objective: </strong>We investigated the myocardial protective effect of sevoflurane in patients receiving off-pump coronary artery bypass grafting (OPCABG) and the role of brain natriuretic peptide (BNP).</p><p><strong>Design: </strong>Forty-eight patients receiving elective OPCABG were randomly assigned to a control group, and to 0.75 MAC, 1.0 MAC and 1.5 MAC sevoflurane groups. Blood samples were collected and levels of BNP and cardiac troponin I (cTnI) were measured before anesthesia, and immediately, 24, 48 and 72 h after surgery.</p><p><strong>Results: </strong>Dopamine was necessary to maintain blood pressure in the sevoflurane groups, but not in the control group (p < 0.002). 1.0 MAC sevoflurane significantly decreased post-surgical cTnI levels (p < 0.001). 0.75 MAC had no significant effect, and increasing sevoflurane concentrations to 1.5 MAC caused no further decrease in cTnI concentrations. There was no significant difference in BNP level among the groups (p = 0.227) or between any two groups, although values of BNP showed a significant correlation with cTnI values in control subjects immediately after (r = 0.847) and 24 h after (r = 0.661) surgery.</p><p><strong>Conclusions: </strong>Our results demonstrated that 1.0 MAC and 1.5 MAC sevoflurane can exert a significant myocardial protective effect. BNP cannot be used to predict the myocardial protective effect of sevoflurane in OPCABG.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"175-84"},"PeriodicalIF":2.2,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2012.760749","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40222531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
Ischemic preconditioning increases myocardial O-GlcNAc glycosylation. 缺血预处理增加心肌O-GlcNAc糖基化。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2013-06-01 Epub Date: 2013-01-10 DOI: 10.3109/14017431.2012.756984
Rebekka Vibjerg Jensen, Jacob Johnsen, Steen Buus Kristiansen, Natasha Elizabeth Zachara, Hans Erik Bøtker
{"title":"Ischemic preconditioning increases myocardial O-GlcNAc glycosylation.","authors":"Rebekka Vibjerg Jensen,&nbsp;Jacob Johnsen,&nbsp;Steen Buus Kristiansen,&nbsp;Natasha Elizabeth Zachara,&nbsp;Hans Erik Bøtker","doi":"10.3109/14017431.2012.756984","DOIUrl":"https://doi.org/10.3109/14017431.2012.756984","url":null,"abstract":"<p><strong>Objectives: </strong>Through the hexosamine biosynthetic pathway (HBP) proteins are modified by O-linked-β-N-acetylglucosamine (O-GlcNAc), which acts as a stress sensor. Augmentation of O-GlcNAc confers cardioprotection against ischemia- reperfusion injury, but its role in ischemic preconditioning (IPC) is unknown. Azaserine and alloxan are unspecific blockers of the HBP and have been used to block the cardioprotective effects of O-GlcNAc. We hypothesized that IPC reduces infarct size and increases O-GlcNAc levels in hearts subjected to ischemia-reperfusion injury, and that these effects could be blocked by azaserine and alloxan.</p><p><strong>Design: </strong>Isolated rat hearts subjected to 40 min global ischemia and 120 min reperfusion were randomized to control, IPC, IPC + azaserine or alloxan, or control + azaserine or alloxan. The effects on infarct size, hemodynamic recovery, myocardial O-GlcNAc levels, and HBP enzyme activities were determined.</p><p><strong>Results: </strong>IPC reduced infarct size, increased O-GlcNAc levels, O-GlcNAc-transferase levels, and O-GlcNAc-transferase activity. Azaserine and alloxan did not block the effect of IPC on O-GlcNAc levels and O-GlcNAc-transferase activity.</p><p><strong>Conclusions: </strong>IPC increased O-GlcNAc levels though increased O-GlcNAc-transferase expression and activity. Azaserine and alloxan failed to block these effects presumably due to poor specificity and sensitivity of the blockers, and IPC-mediated cardioprotection may therefore still be dependent on O-GlcNAc.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"168-74"},"PeriodicalIF":2.2,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2012.756984","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40220896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 35
No effect of combined coenzyme Q10 and selenium supplementation on atorvastatin-induced myopathy. 辅酶Q10和硒联合补充对阿托伐他汀诱导的肌病无影响。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2013-04-01 Epub Date: 2013-01-10 DOI: 10.3109/14017431.2012.756119
Martin Prøven Bogsrud, Gisle Langslet, Leiv Ose, Kjell-Erik Arnesen, Milada Cvancarova Sm Stuen, Ulrik Fredrik Malt, Berit Woldseth, Kjetil Retterstøl
{"title":"No effect of combined coenzyme Q10 and selenium supplementation on atorvastatin-induced myopathy.","authors":"Martin Prøven Bogsrud,&nbsp;Gisle Langslet,&nbsp;Leiv Ose,&nbsp;Kjell-Erik Arnesen,&nbsp;Milada Cvancarova Sm Stuen,&nbsp;Ulrik Fredrik Malt,&nbsp;Berit Woldseth,&nbsp;Kjetil Retterstøl","doi":"10.3109/14017431.2012.756119","DOIUrl":"https://doi.org/10.3109/14017431.2012.756119","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the present study was to evaluate the possible effects of Q10 and selenium supplementation on statin-induced myopathy (SIM), both for subjective symptoms and muscle function.</p><p><strong>Design: </strong>Patients (N = 43) who had experienced previous or ongoing SIM on atorvastatin therapy were recruited. Following a 6-week washout period during which no statins were administered, the patients were re-challenged with 10 mg of atorvastatin. Patients (N = 41) who experienced SIM continued the atorvastatin treatment and were in addition randomized to receive 12 weeks supplement of 400 mg Q10 and 200 μg selenium per day or a matching double placebo. SIM was assessed using 3 validated symptom questionnaires, and a muscle function test was performed at the beginning and at the end of the study.</p><p><strong>Results: </strong>The patients receiving the active supplement experienced significant increases in their serum Q10 and selenium concentrations compared with the group receiving placebo. No statistically significant differences in symptom questionnaire scores or muscle function tests were revealed between the groups.</p><p><strong>Conclusions: </strong>Despite substantial increases in the serum Q10 and selenium levels following the oral supplementation, this study revealed no significant effects on SIM compared with the placebo.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"80-7"},"PeriodicalIF":2.2,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2012.756119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40223387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Deep sternal wound infection after open heart surgery--reconstructive options. 心脏直视手术后深胸骨伤口感染——重建方案。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2012-10-01 Epub Date: 2012-03-29 DOI: 10.3109/14017431.2012.674549
Alexander Andersen Juhl, Vibeke Koudahl, Tine Engberg Damsgaard
{"title":"Deep sternal wound infection after open heart surgery--reconstructive options.","authors":"Alexander Andersen Juhl,&nbsp;Vibeke Koudahl,&nbsp;Tine Engberg Damsgaard","doi":"10.3109/14017431.2012.674549","DOIUrl":"https://doi.org/10.3109/14017431.2012.674549","url":null,"abstract":"<p><strong>Objectives: </strong>The management of sternal defects arisen after deep sternal wound infection is challenging and often requires extensive interdisciplinary teamwork between plastic and thoracic surgeons. In this study, the published literature on methods used to reconstruct sternal defects arisen as a result of deep sternal wound infection after open-heart surgery will be reviewed.</p><p><strong>Design: </strong>The Cochrane, Embase, PubMed, and SveMed + databases were searched in December 2011. Only papers regarding treatment of deep sternal wound infection after open-heart surgery in adults were included.</p><p><strong>Results: </strong>The literature search identified 224 original papers that met the inclusion criteria. The majority dealt with surgical techniques. None of the studies regarding reconstructive options were designed as randomized controlled trials, and the levels of evidence are generally low.</p><p><strong>Conclusion: </strong>The treatment of deep sternal wound infection has evolved considerably, but there is still little consensus regarding optimal surgical management and a general lack of a standard treatment protocol. The use of muscle flap transposition is well documented. Recent studies recommend the use of topical negative pressure therapy as an adjunct to surgical reconstruction.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"254-61"},"PeriodicalIF":2.2,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2012.674549","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40152899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Wake-up times following sedation with sevoflurane versus propofol after cardiac surgery. 心脏手术后七氟醚与异丙酚镇静后的唤醒时间。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2012-10-01 Epub Date: 2012-03-29 DOI: 10.3109/14017431.2012.676209
Jan Hellström, Anders Öwall, Peter V Sackey
{"title":"Wake-up times following sedation with sevoflurane versus propofol after cardiac surgery.","authors":"Jan Hellström,&nbsp;Anders Öwall,&nbsp;Peter V Sackey","doi":"10.3109/14017431.2012.676209","DOIUrl":"https://doi.org/10.3109/14017431.2012.676209","url":null,"abstract":"<p><strong>Objectives: </strong>Intravenous sedation in the intensive care unit (ICU) may contribute to altered consciousness and prolonged mechanical ventilation. We tested the hypothesis that replacing intravenous propofol with inhaled sevoflurane for sedation after cardiac surgery would lead to shorter wake-up times, quicker patient cooperation, and less delusional memories.</p><p><strong>Design: </strong>Following coronary artery bypass surgery with cardiopulmonary bypass, 100 patients were randomized to sedation with sevoflurane via the anesthetic conserving device or propofol. Study drugs were administered for a minimum of 2 hours until criteria for extubation were met. Primary endpoints were time from drug stop to extubation and to adequate verbal response. Secondary endpoints were adverse recovery events, memories reported in the ICU Memory Tool test, and ICU/hospital stay.</p><p><strong>Results: </strong>Median time from drug stop to extubation (interquartile range/total range) was shorter after sevoflurane compared to propofol sedation; 10 (10/100) minutes versus 25 (21/240) minutes (p <0.001). Time from extubation to adequate verbal response was shorter (p =0.036). No differences were found in secondary endpoints.</p><p><strong>Conclusions: </strong>Sevoflurane sedation after cardiac surgery leads to shorter wake-up times and quicker cooperation compared to propofol. No differences were seen in ICU-stay, adverse memories or recovery events in our short-term sedation.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"262-8"},"PeriodicalIF":2.2,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2012.676209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40167087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 50
High-sensitive troponin T and N-terminal-brain-natriuretic-peptide predict outcome in symptomatic aortic stenosis. 高敏感肌钙蛋白T和脑钠肽n端预测症状性主动脉狭窄的预后。
IF 2.2
Scandinavian cardiovascular journal : SCJ Pub Date : 2012-10-01 Epub Date: 2012-05-16 DOI: 10.3109/14017431.2012.687836
Ole Geir Solberg, Thor Ueland, Ragnhild Wergeland, Christen P Dahl, Svend Aakhus, Pål Aukrust, Lars Gullestad
{"title":"High-sensitive troponin T and N-terminal-brain-natriuretic-peptide predict outcome in symptomatic aortic stenosis.","authors":"Ole Geir Solberg,&nbsp;Thor Ueland,&nbsp;Ragnhild Wergeland,&nbsp;Christen P Dahl,&nbsp;Svend Aakhus,&nbsp;Pål Aukrust,&nbsp;Lars Gullestad","doi":"10.3109/14017431.2012.687836","DOIUrl":"https://doi.org/10.3109/14017431.2012.687836","url":null,"abstract":"<p><strong>Objectives: </strong>Aortic stenosis (AS) and atherosclerosis share similarities when it comes to risk factors and disease progression. Like in other heart diseases, we hypothesized that biomarkers like high-sensitive troponin T (hsTnT), N-terminal-pro-brain-natriuretic-peptide (NT-proBNP) and high-sensitive C-reactive protein (hsCRP) could be useful in risk stratification.</p><p><strong>Design: </strong>A total of 136 patients (57% men, mean age 74 years), referred for evaluation of AS (valve area 0.62 cm(2), left ventricular ejection fraction 64%) were consecutively enrolled in the study. The relationship between hsTnT, hsCRP and NT-proBNP, different echocardiographic parameters of AS and cardiac function were investigated as well as their relation to all-cause mortality.</p><p><strong>Results: </strong>In contrast to hsCRP, hsTnT and NT-proBNP were individually correlated with prognosis. Regression analysis identified diabetes and the combination of hsTnT and NT-proBNP as significant predictors of all-cause mortality. When analyzing patients without surgery separately, only the combination of hsTnT and NT-proBNP were identified as a significant predictor of all-cause mortality in multivariable analysis.</p><p><strong>Conclusion: </strong>The combination of NT-proBNP and hsTnT came out as the strongest predictor of outcome irrespective of surgical treatment or not and could be of particular interest in risk-stratification in AS-patients. The results should be confirmed in prospective studies both in symptomatic and asymptomatic patients.</p>","PeriodicalId":137876,"journal":{"name":"Scandinavian cardiovascular journal : SCJ","volume":" ","pages":"278-85"},"PeriodicalIF":2.2,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/14017431.2012.687836","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40192382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
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