International dental journal最新文献

{"title":"Comparison of Microbiota in Zirconia and Titanium Implants: A Qualitative Systematic Review.","authors":"Majid Bonyadi Manesh, Neda Vatankhah, Fatemeh Bonyadi Manesh","doi":"10.1016/j.identj.2024.08.001","DOIUrl":"https://doi.org/10.1016/j.identj.2024.08.001","url":null,"abstract":"<p><strong>Background: </strong>In this systematic review, we examine the variations in microbiota on zirconia versus titanium implants, providing insights into their impact on dental health and outcomes. The ongoing discussion regarding whether to use zirconia or titanium for implants underscores the significance of microbiota colonization in determining the longevity and performance of implants.</p><p><strong>Methods: </strong>Research questions were formulated following the Participants, Intervention, Comparison, and Outcomes framework, and a PROSPERO protocol was registered. A thorough systematic search was carried out in PubMed, Embase, and Web of Science. Two reviewers independently assessed the reports against the Participants, Intervention, Comparison, and Outcomes criteria, including the inclusion and exclusion criteria. Risk of bias was assessed using the Quality Assessment Tool for In Vitro Studies (QUIN Tool).</p><p><strong>Results: </strong>Of the 2063 articles identified, 19 articles fulfilled the inclusion criteria and subjected to quality assessment. All of the included studies were in vitro research with low (31.5%) or moderate (36.8%) or high (31.5%) risk of bias and reported data from 2 implant abutments. Zirconia implants displayed a higher occurrence of Gram-negative bacteria, such as Tannerella, Aggregatibacter, and Porphyromonas. In contrast, titanium implants showed a greater prevalence of Gram-positive bacteria, including Streptococcus, Lactobacillus acidophilus, and Staphylococcus species.</p><p><strong>Conclusion: </strong>According to the findings of the current study, both zirconia and titanium implants support the growth of different microorganisms. There were also differences in the quakity and the quantity of microorganisms detected on each material. These differences in microbial profiles indicate that the selection of implant material might impact the microbial ecosystem on the implant surface, potentially affecting clinical outcomes such as infection rates and the longevity of the implant.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal Relationship Between Autoimmune Arthritis and Temporomandibular Disorders.","authors":"Xue-Feng Li, Jun-Wei Cai, Yuan-Yuan Hu, Yu-Ming Niu","doi":"10.1016/j.identj.2024.08.006","DOIUrl":"https://doi.org/10.1016/j.identj.2024.08.006","url":null,"abstract":"<p><strong>Objective: </strong>Accumulating evidence has indicated a close interrelation between autoimmune arthritis (AA) and temporomandibular disorders (TMD), but the causality is still unclear. The study aimed to explore the causal inference between AA and TMD using a bidirectional Mendelian randomization analysis.</p><p><strong>Methods: </strong>Online genome-wide association study data on rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis, and TMD were obtained from the FinnGen and IEU databases. Causality was using the inverse variance-weighted method as the primary analysis and supplemented by other methods. Sensitivity analyses, including heterogeneity tests, horizontal pleiotropy tests, and leave-one-out methods, were conducted to investigate the stability and reliability of the results.</p><p><strong>Results: </strong>The inverse variance-weighted test indicated that several AA types could causally increase the TMD risk, including overall RA (odds ratio [OR] = 1.348, 95% confidence interval [CI] = 1.1232-1.618, P = .001), subtype nRA (OR = 1.118, 95% CI = 1.044-1.197, P = .001), and AS (OR = 1.060, 95% CI = 1.024-1.097, P = .001). Moreover, the causal association of the above combinations has been proven to be stable and reliable using sensitivity and other tests.</p><p><strong>Conclusion: </strong>These findings suggest that RA and AS might be causally associated with an increased risk of TMD. However, more studies are needed to check the causal effects of AA on TMD and analyse the potential mechanisms further.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transfer Learning-Based Classifier to Automate the Extraction of False X-Ray Images From Hospital's Database.","authors":"Manar Abu Talib, Mohammad Adel Moufti, Qassim Nasir, Yousuf Kabbani, Dana Aljaghber, Yaman Afadar","doi":"10.1016/j.identj.2024.08.002","DOIUrl":"https://doi.org/10.1016/j.identj.2024.08.002","url":null,"abstract":"<p><strong>Background: </strong>During preclinical training, dental students take radiographs of acrylic (plastic) blocks containing extracted patient teeth. With the digitisation of medical records, a central archiving system was created to store and retrieve all x-ray images, regardless of whether they were images of teeth on acrylic blocks, or those from patients. In the early stage of the digitisation process, and due to the immaturity of the data management system, numerous images were mixed up and stored in random locations within a unified archiving system, including patient record files. Filtering out and expunging the undesired training images is imperative as manual searching for such images is problematic. Hence the aim of this stidy was to differentiate intraoral images from artificial images on acrylic blocks.</p><p><strong>Methods: </strong>An artificial intelligence (AI) solution to automatically differentiate between intraoral radiographs taken of patients and those taken of acrylic blocks was utilised in this study. The concept of transfer learning was applied to a dataset provided by a Dental Hospital.</p><p><strong>Results: </strong>An accuracy score, F1 score, and a recall score of 98.8%, 99.2%, and 100%, respectively, were achieved using a VGG16 pre-trained model. These results were more sensitive compared to those obtained initally using a baseline model with 96.5%, 97.5%, and 98.9% accuracy score, F1 score, and a recall score respectively.</p><p><strong>Conclusions: </strong>The proposed system using transfer learning was able to accurately identify \"fake\" radiographs images and distinguish them from the real intraoral images.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI Revolutionizes Cellular Reprogramming of Periodontal Ligament.","authors":"Pradeep Kumar Yadalam, Susmitha Munivel, Carlos M Ardila","doi":"10.1016/j.identj.2024.08.009","DOIUrl":"https://doi.org/10.1016/j.identj.2024.08.009","url":null,"abstract":"","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Artificial Intelligence Into Orthodontic Education and Practice.","authors":"Pradeep Kumar Yadalam, Raghavendra Vamsi Anegundi, Carlos M Ardila","doi":"10.1016/j.identj.2024.08.011","DOIUrl":"https://doi.org/10.1016/j.identj.2024.08.011","url":null,"abstract":"","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ginsenoside RB1 Influences Macrophage-DPSC Interactions in Inflammatory Conditions.","authors":"Wenlan Li, Yuting Wang, Wenli Mu, Yonghui Guan, Yao Yang, Yifei Tang, Mingfei Wang, Yu Piao, Tiezhou Hou, Xiaoyue Guan","doi":"10.1016/j.identj.2024.07.1213","DOIUrl":"https://doi.org/10.1016/j.identj.2024.07.1213","url":null,"abstract":"<p><strong>Introduction and aims: </strong>Unresolved inflammation and tissue destruction are supposed to underlie the failure of dental pulp repair. As crucial regulators of the injury response, dental pulp stem cells (DPSCs) play a key role in pulp tissue repair and regeneration. M2 macrophages have been demonstrated to induce osteogenic/odontogenic differentiation of DPSCs. Ginsenoside Rb1 (GRb1) is the major component of ginseng and manifested an anti-inflammatory role by promoting M1 macrophage polarised into M2 macrophage in inflammatory disease. However, whether GRb1 facilitates odontogenic differentiation of DPSCs via promoting M2 macrophage polarisation under inflammatory conditions has yet to be established.</p><p><strong>Methods: </strong>Human monocyte leukemic cells (THP-1) differentiated macrophages were induced into M1 subsets and then treated with GRb1. After that, the conditioned medium was added to DPSCs. The cell co-cultured system was then subjected to odontogenic differentiation in osteogenic media. Effects of GRb1 on human dental pulp stem cells' (hDPSCs') osteogenic/odontogenic differentiation under inflammatory conditions were assessed by alkaline phosphatase (ALP) staining, Alizarin Red S (ARS) staining, and quantitative polymerase chain reaction testing.</p><p><strong>Results: </strong>Results demonstrated that GRb1 could facilitate the polarisation of macrophages from the M1 subtype to the M2 subtype. Conditioned medium from GRb1 + M1 macrophages, in comparison with M1 macrophages, may markedly increase the gene expression of ALP, DSPP, and DMP1. Moreover, ALP and ARS staining uncovered that the osteogenic/odontogenic differentiation ability of hDPSCs was strengthened in the M1 + GRb1 co-culture group.</p><p><strong>Conclusions: </strong>GRb1 plays a crucial role in the inflammatory response and reparative dentine formation after dental pulp injury. Findings show that GRb1 modulates the interaction between macrophages and DPSCs during inflammation. The current study discusses modifications of deep caries therapy.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142080251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validating Caries Risk Assessment Tools in High-Prevalence Filipino Toddlers.","authors":"Maritess Oliveros-Villarico, Patimaporn Pungchanchaikul, Supatra Watthanasaen, Waranuch Pitiphat","doi":"10.1016/j.identj.2024.07.1217","DOIUrl":"https://doi.org/10.1016/j.identj.2024.07.1217","url":null,"abstract":"<p><strong>Introduction and aims: </strong>Caries risk assessment is an essential part of the diagnostic process. Many studies have assessed these tools, proving their effectiveness in reducing future caries risk in developed countries with low caries prevalence. However, Filipino children have consistently registered high caries prevalence rates in successive official surveys. This prospective study aimed to compare the validity of available caries risk assessment tools in predicting future caries among a high-caries-prevalent population in the Philippines.</p><p><strong>Methods: </strong>From the vaccination registry of community health centres in Caloocan City, Philippines, children aged 4-24 months underwent oral examinations according to modified International Caries Detection and Assessment System (ICDAS) criteria, and their primary caregivers were interviewed using a structured questionnaire. Baseline caries risk categories were evaluated using 3 available tools, without biological tests. Caries incidence was recorded during the follow-up visit after 2 years.</p><p><strong>Results: </strong>Baseline oral examinations in 703 toddlers (mean age: 13.3 months, standard deviation (SD) 2.4) revealed a high caries prevalence of 29.2%. Of the 654 eligible children without cavitated caries at baseline, 323 (mean age: 35.6 months, SD 5.1) attended the 2-year follow-up visit, with a caries incidence (cavitated and non-cavitated) of 76.5%. Caries-risk Assessment Form (CrAF) demonstrated high sensitivity but low specificity scores (93.1% and 3.9%), while Caries Management by Risk Assessment (CAMBRA) showed similar patterns (71.7% and 34.2%). Conversely, Cariogram exhibited low sensitivity but high specificity (23.5% and 80.3%).</p><p><strong>Conclusion: </strong>Among CrAF, CAMBRA or Cariogram, no assessment tool came close (sensitivity + specificity < 160) to effectively identify toddlers highly at risk of caries development.</p><p><strong>Clinical relevance: </strong>Current CRA tools lack sufficient accuracy in predicting caries development in high-risk populations like Filipino children. Refinement or development of more valid tools is crucial for implementing effective caries prevention strategies at both individual and population levels.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142055514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the Silent Crisis of Oral Health in Conflict Areas and War Zones","authors":"","doi":"10.1016/j.identj.2024.07.016","DOIUrl":"10.1016/j.identj.2024.07.016","url":null,"abstract":"","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0020653924002089/pdfft?md5=3ba5e4ea02a192ae23a0b23f85275ae9&pid=1-s2.0-S0020653924002089-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthy Dietary Pattern Improves Cognitive Function in Elderly Persons With Periodontitis: A Cross-Sectional Study of NHANES.","authors":"Yu Li, Ling Qiu, Chengbin Zhang","doi":"10.1016/j.identj.2024.07.1207","DOIUrl":"https://doi.org/10.1016/j.identj.2024.07.1207","url":null,"abstract":"<p><strong>Aim: </strong>Cognitive decline is thought to be more prevalent in elderly persons with periodontitis. Greater adherence to Healthy Eating Index (HEI)-2015 has been reported to improve cognitive function in the elderly population. However, whether the benefits of HEI-2015 on cognitive function apply to elderly patients with periodontitis remains unknown.</p><p><strong>Methods: </strong>This is a cross-sectional study based on the National Health and Nutrition Examination Survey (NHANES). The data were extracted from database 2011-2014. Cognitive function was measured through the Consortium to Establish a Registry for Alzheimer's Disease battery for immediate recall (CERAD-WL) and delayed recall (CERAD-DR), Animal Fluency Test (AFT), and Digit Symbol Substitution Test (DSST). The data of HEI-2015 were acquired from 24-hour dietary recalls. Weighted linear regression models were performed to investigate the association between HEI-2015 and cognitive function in elderly patients with periodontitis. The associations were further investigated in subgroups of sex, cardiovascular disease status, and depression status.</p><p><strong>Results: </strong>A total of 1862 participants were included, and 1223 of them had periodontitis. Periodontitis was negatively associated with cognitive function (β = -0.45; 95% confidence interval [CI], -0.87 to -0.03). No statistically significant relationship was observed between HEI-2015 and cognitive function (β = 0.33; 95% CI, -0.02 to 0.69). Low HEI-2015 score was associated with high odds of cognitive decline in patients with periodontitis (β = -0.73; 95% CI, -1.25 to -0.21; P for trend = .01). Higher HEI-2015 was related to the lower incidence of cognitive function decline in patients with periodontitis who were female (β = -0.53; 95% CI, -1.03 to -0.03), had a socioeconomic status from 0 to 3 (β = -0.55; 95% CI, -1.00 to -0.09), did not have cardiovascular disease (β = -0.60; 95% CI, -1.14 to -0.05), and did not have depression (β = -0.57; 95% CI, -1.11 to -0.03).</p><p><strong>Conclusions: </strong>Greater HEI-2015 adherence may improve cognitive function amongst elderly patients with periodontitis. Further studies are needed to investigate this putative association in elderly persons with periodontitis.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Predictive Value of BUB1 in the Prognosis of Oral Squamous Cell Carcinoma.","authors":"Xiaoqian Li","doi":"10.1016/j.identj.2024.07.012","DOIUrl":"https://doi.org/10.1016/j.identj.2024.07.012","url":null,"abstract":"<p><strong>Background: </strong>Oral squamous cell carcinoma (OSCC) is the most common type of malignant tumour in the oral cavity, and it is known for its poor prognosis. Budding uninhibited by benzimidazoles 1 (BUB1) may be related to cancer prognosis; however, the specific relationship between BUB1 and OSCC prognosis remains largely unexplored.</p><p><strong>Methods: </strong>The mRNA levels of BUB1 were analysed using data from the TCGA_OSCC and GSE23558 cohorts. OSCC samples from the TCGA_OSCC dataset were divided into low- and high-BUB1 expression groups based on the median BUB1 level. Furthermore, results of survival analysis, tumour mutation burden (TMB), gene set enrichment analysis (GSEA) pathways, and drug-sensitivity analysis were compared between the 2 groups.</p><p><strong>Results: </strong>Based on the data from the TCGA_OSCC and GSE23558 cohorts, BUB1 mRNA levels were significantly upregulated in OSCC tissues compared to healthy controls. Moreover, high expression of BUB1 may serve as an independent indicator of poor prognosis in OSCC. Additionally, patients with high BUB1 expression also exhibited increased levels of immune checkpoints and TMB, suggesting that patients with high BUB1 expression may benefit from immunotherapy. Mechanistically, transcription factors ZFP64, TCF3, and ZNF281 were found to potentially bind to the promoter region of BUB1, thereby regulating its gene expression. Furthermore, GSEA results showed that BUB1 expression was closely related to cell cycle and tumour-related pathways in OSCC. Drug-sensitivity analysis showed that patients with high BUB1 expression may be more sensitive to gemcitabine, paclitaxel, or imatinib.</p><p><strong>Conclusions: </strong>Collectively, results demonstrated that high BUB1 levels may be related to a poor prognosis of OSCC, highlighting its potential as a novel prognostic biomarker for OSCC.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}