International dental journal最新文献

{"title":"Erratum to ‘Is Simulation of Glued Contact Sufficient to Simulate Nonlinear Failure Behaviour in Dental Shear Bond Strength Tests?’ [International Dental Journal Volume 75, Issue 3, June 2025, Pages 1746-1758]","authors":"Ahmed M. Ismail , Ahmed ElBanna , Tamer M. Nassef , Ludger Keilig , Christoph Bourauel","doi":"10.1016/j.identj.2025.100915","DOIUrl":"10.1016/j.identj.2025.100915","url":null,"abstract":"","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100915"},"PeriodicalIF":3.2,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value of Panoramic Radiographs in the Assessment of Degenerative Joint Disease: A Retrospective Study","authors":"Ibraheem Maita ,&nbsp;Abhinav Dhillon ,&nbsp;Reid Friesen ,&nbsp;Fabiana T. Almeida","doi":"10.1016/j.identj.2025.100910","DOIUrl":"10.1016/j.identj.2025.100910","url":null,"abstract":"<div><h3>Introduction and Aims</h3><div>This study evaluated the potential of panoramic radiographs (PR) for assessing temporomandibular joint (TMJ) osseous changes compared to Cone-beam Computed Tomography (CBCT). Our ultimate goal is to understand the value of PR as a screening tool and to get guidance for when CBCT should be requested for further investigation.</div></div><div><h3>Methods</h3><div>This cross-sectional retrospective study included patients 18 years or older with a PR and CBCT of TMJ from the School of Dentistry, University of Alberta, between 2021 and 2024. Exclusion criteria included poor image quality, an interval between PR and CBCT over 6 months, and TMJ not fully captured. Assessed findings from the images included condyle and articular eminence flattening, altered size, osteophyte formation, sclerosis, and erosion. Statistical analyses verified the diagnostic accuracy of PR in identifying TMJ degenerative findings compared to CBCT, the reference standard.</div></div><div><h3>Results</h3><div>One hundred and two TMJs from 51 patients (40 females and 11 males) were included in the study. PR sensitivity was below diagnostic thresholds recommended by current guidelines, ranging from 0 to 0.57, with only condyle flattening (0.55) and condyle altered shape/size (0.57), with a sensitivity above 0.50. A true negative was the most frequent score for all osseous findings except for flattening the condyle, with a high true positive in 32.25% of the cases. The specificity of PR ranged from 0.71 to 1.00.</div></div><div><h3>Conclusion</h3><div>PR is an opportunistic screening tool but does not meet sensitivity thresholds to serve as a stand-alone diagnostic method for TMJ DJD. Abnormal findings seen in the PR should prompt CBCT to confirm osseous pathology.</div></div><div><h3>Clinical Relevance</h3><div>PR is widely used in dental practice and may reveal gross TMJ abnormalities. When these findings align with clinical signs or symptoms, CBCT should be considered for further assessment. This approach supports earlier detection of DJD while adhering to the ALADAIP principle.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100910"},"PeriodicalIF":3.2,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144665779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Finite Element Analysis of the Impact of Ferrule Height and Post-Core Materials on Stress Distribution in Incisors","authors":"Beibei Yang ,&nbsp;Boxuan Wang ,&nbsp;Liangzhi Du ,&nbsp;Fang Wang","doi":"10.1016/j.identj.2025.100918","DOIUrl":"10.1016/j.identj.2025.100918","url":null,"abstract":"<div><h3>Objective</h3><div>Ferrule heights and post-core materials are key factors for post-core restorations, and the interaction between them needs further investigation. This study used finite element analysis to evaluate the stress distribution of post-core models with different materials and varying ferrule heights.</div></div><div><h3>Methods</h3><div>A 3-dimensional finite element model of the maxillary central incisor was constructed, along with 3 additional groups with different ferrule heights: 2 mm, 1 mm, and 0 mm. Meanwhile, various materials were designed to form the post-core: Zirconia, Titanium, Fiberglass, PEEK, and CFR-PEEK (PEEK reinforced by 30% carbon fiber). A 100 N load was applied at an angle of 45° with the tooth's longitudinal axis on the palatal surface of the crown. The peak von Misses (VM) stress values were recorded.</div></div><div><h3>Results</h3><div>As the ferrule height increased, a stress reduction was observed at post-core and post-cement interfaces, while the stress in root and cement interfaces increased; meanwhile, the peak VM stress of the post-core decreased among all groups, while that of rigid material groups (Zirconia/Titanium) decreased more significantly; in addition, the peak VM stress at post-core and cement interfaces increased, and that of the 0 mm ferrule PEEK group was the highest.</div></div><div><h3>Conclusion</h3><div>Ferrule heights and post-core materials affect stress distribution on post-core restorations. A sufficiently large ferrule height can effectively compensate for the stress concentration of highly rigid materials, and PEEK post-core should be carefully used in 0 mm ferrule cases.</div></div><div><h3>Clinical relevance</h3><div>This study would provide suggestions for dentists to choose appropriate post-core materials according to various ferrule heights.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100918"},"PeriodicalIF":3.2,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144665975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National Pharmacovigilance Assessment of Oral Adverse Events Following COVID-19 Vaccination in Germany (2020-2023)","authors":"Abanoub Riad","doi":"10.1016/j.identj.2025.100906","DOIUrl":"10.1016/j.identj.2025.100906","url":null,"abstract":"<div><h3>Objectives</h3><div>Pharmacovigilance efforts for COVID-19 vaccines have largely focused on severe adverse events (AEs), while nonserious, yet distressing, AEs, such as oral AEs, remain underexamined. This study aimed to analyse oral AE reporting patterns in the German national pharmacovigilance database.</div></div><div><h3>Methods</h3><div>A retrospective analysis of individual case safety reports (ICSRs) from the Paul-Ehrlich-Institut (PEI) database was conducted for December 2020 to December 2023. The absolute reporting ratio was calculated as cases per 1000 ICSRs for each oral AE. Secondary analyses included: (1) cross-database comparisons with the U.S. Vaccine Adverse Event Reporting System (VAERS); (2) disproportionality analysis using a hybrid approach combining frequentist and Bayesian conditions to establish signals of disproportionate reporting (SDRs); (3) subgroup analyses based on demographic and vaccine-related factors; and (4) multivariable regression to adjust for potential confounders.</div></div><div><h3>Results</h3><div>Gustatory AEs, such as ageusia and dysgeusia; other oral sensory AEs, including oral paraesthesia and oral hypoaesthesia; and specific mucosal AEs, such as oral herpes and aphthous stomatitis, were the most frequently reported oral AEs in the PEI dataset. Cross-database analysis not only confirmed the prominence of gustatory and other sensory AEs but also highlighted differences, with VAERS reporting higher rates of swollen tongue and lip swelling. Disproportionality analysis identified 21 oral AEs as true SDRs. Female susceptibility was evident in several oral AEs, and age-stratified analysis revealed higher reporting among minors and seniors compared to middle-aged adults. Differences in oral AE reporting between mRNA and viral vector vaccines lacked a consistent pattern, and booster doses were associated with increased reporting of select oral AEs.</div></div><div><h3>Conclusions</h3><div>Within the limitations of passive surveillance data, this study highlights the need for further research on oral AEs using self-controlled case-series designs for clinically significant events. Integrating oral AEs into vaccine safety monitoring could improve postmarketing surveillance, while validated AEs may warrant inclusion in product information for transparency.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100906"},"PeriodicalIF":3.2,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automatic Point Cloud Patching of Intraoral Three-Dimensional Scanning Based on Deep Learning","authors":"Qianhan Zheng ,&nbsp;Yimin Wang ,&nbsp;Mengqi Zhou ,&nbsp;Yongjia Wu ,&nbsp;Jiahao Chen ,&nbsp;Xiaozhe Wang ,&nbsp;Lixia Gao ,&nbsp;Ting Kang ,&nbsp;Xuepeng Chen ,&nbsp;Weifang Zhang","doi":"10.1016/j.identj.2025.100911","DOIUrl":"10.1016/j.identj.2025.100911","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Intraoral scanning (IOS) captures real-time surface morphology of teeth and is widely used in clinical dentistry. However, due to the complex intraoral environment, data loss during scanning is common, leading to incomplete three-dimensional (3D) point clouds. This study aimed to develop and evaluate a deep learning–based method to automatically restore missing regions in intraoral 3D point clouds, thereby improving the accuracy and efficiency of digital orthodontic workflows.</div></div><div><h3>Methods</h3><div>A Point Fractal Network architecture was adopted to reconstruct incomplete IOS data. A dataset comprising 314 IOS scans and 4162 individual teeth was used for training and validation. Missing data were simulated by removing random portions of point clouds (5%, 10%, 15%, and 20%). Model performance was assessed using Chamfer distance (CD) to measure the accuracy of point cloud completion across different levels of data loss.</div></div><div><h3>Results</h3><div>The proposed method achieves robust performance, maintaining average CD values below 0.01 across most levels of simulated data loss. Visual comparisons confirmed high geometric fidelity between the completed and original point clouds. Furthermore, the model demonstrated efficient processing, completing each point cloud in approximately 0.5 seconds, enabling near real-time restoration during clinical scanning.</div></div><div><h3>Conclusion</h3><div>The deep learning–based model accurately restores missing IOS data, improving the precision and efficiency of digital dental workflows. Its speed and accuracy support real-time clinical applications and reduce reliance on manual corrections.</div></div><div><h3>Clinical Relevance</h3><div>This method improves clinical efficiency, reduces chairside time, and enhances both patient comfort and treatment acceptance. In addition, it minimises human error and increases the precision of dental restorations. As digital dentistry continues to evolve, this approach holds great potential for improving the accuracy and efficiency of dental treatments, paving the way for broader artificial intelligence integration in clinical practice.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100911"},"PeriodicalIF":3.2,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Responses to Comments on \"Image-Based Diagnostic Performance of LLMs vs CNNs for Oral Lichen Planus\".","authors":"Paak Rewthamrongsris, Jirayu Burapacheep, Ekarat Phattarataratip, Promphakkon Kulthanaamondhita, Antonin Tichy, Falk Schwendicke, Thanaphum Osathanon, Kraisorn Sappayatosok","doi":"10.1016/j.identj.2025.100889","DOIUrl":"https://doi.org/10.1016/j.identj.2025.100889","url":null,"abstract":"","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":" ","pages":"100889"},"PeriodicalIF":3.2,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ARA290 Attenuates Apical Periodontitis via SIRT1/NF-κB/IL-1β Pathway Modulation","authors":"Yuting Wang ,&nbsp;Yifei Tang ,&nbsp;Mingfei Wang ,&nbsp;Wenlan Li ,&nbsp;Wenli Mu ,&nbsp;Abdelrahman Seyam ,&nbsp;Yating Dai ,&nbsp;Tiezhou Hou ,&nbsp;Xiaoyue Guan","doi":"10.1016/j.identj.2025.100863","DOIUrl":"10.1016/j.identj.2025.100863","url":null,"abstract":"<div><h3>Introduction and Aims</h3><div>Existing research suggests that ARA290 may possess therapeutic potential for apical periodontitis (AP), although the mechanisms involved remain unclear. This study aims to investigate the protective effects and underlying mechanisms of ARA290 in mitigating pro-inflammatory responses of macrophages in the context of AP.</div></div><div><h3>Methods</h3><div>Initially, <em>in vivo</em> models of AP were used to assess the aberrant activation of the SIRT1/NF-κB/IL-1β signalling pathway within periapical lesions. Furthermore, the expression levels of the SIRT1/NF-κB/IL-1β signalling pathway in ARA290-treated AP models, both <em>in vivo</em> and <em>in vitro</em>, were evaluated using immunohistochemistry (IHC), Western blotting, and immunofluorescence (IF) techniques to elucidate the role of ARA290 in modulating this signalling pathway during AP pathogenesis. Subsequently, the SIRT1/NF-κB/IL-1β signalling pathway was inhibited using selisistat, and the resultant changes in inflammatory levels and bone resorption in periapical lesions were assessed through haematoxylin and eosin staining, tartrate-resistant acid phosphatase staining, IHC and micro-computed tomography (Micro CT).</div></div><div><h3>Results</h3><div>The <em>in vivo</em> AP model demonstrated a 50% reduction in SIRT1 expression within periapical lesions, accompanied by a 5-fold increase in the expression of acetylated NF-κB (p65) and IL-1β. Additionally, the administration of ARA290 in the AP mouse model significantly reduced inflammatory infiltration, the number of osteoclasts and the extent of bone loss in the periapical region. Notably, ARA290 treatment enhanced SIRT1 expression by approximately 40% while concurrently decreasing the levels of acetylated NF-κB (p65) by around 75% and IL-1β by approximately 62.5% in both <em>in vivo</em> and <em>in vitro</em> AP models. Importantly, inhibition of the SIRT1/NF-κB/IL-1β signalling pathway negated the beneficial effects of ARA290 in attenuating the progression of AP.</div></div><div><h3>Conclusions</h3><div>ARA290 plays a protective role by modulating the SIRT1/NF-κB/IL-1β signalling pathway in apical periodontitis, which may provide a new direction for the adjuvant treatment of apical periodontitis.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100863"},"PeriodicalIF":3.2,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Parental Health Beliefs on Early Childhood Caries: A Two-Year Longitudinal Study","authors":"Yi-Chang Chou ,&nbsp;Feng-Shiang Cheng ,&nbsp;Shih-Han Weng ,&nbsp;Chih-Hao Tseng ,&nbsp;Hsiao-Yun Hu ,&nbsp;Chieh-Hsing Liu","doi":"10.1016/j.identj.2025.100902","DOIUrl":"10.1016/j.identj.2025.100902","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Early childhood caries (ECC) is a widespread chronic condition that significantly affect children’s health and well-being. Although parental psychosocial factors are key to shaping children’s oral health behaviours, few studies have examined the distinct influences of fathers’ vs mothers’ health beliefs. The Health Belief Model (HBM) – which examines health behaviours through perceived susceptibility, severity, benefits, barriers, and self-efficacy – provides a valuable framework for examining these dynamics. This study applied the HBM to investigate the associations between caregiver beliefs, behaviours, and ECC risk, with a focus on differences between fathers and mothers.</div></div><div><h3>Methods</h3><div>We conducted a longitudinal analysis utilizing data from the Taipei Preschool Oral Health Screening Program (2017-2018), including children aged 3-5 years. Eligible participants had complete oral examination records and parental HBM-based questionnaires for 2 consecutive years. Children with incomplete questionnaires were excluded, yielding a final sample of 6902. Generalized estimating equations assessed associations between caregiver oral health beliefs, self-efficacy, perceived barriers, cues to action, behaviours, and ECC risk, stratified by caregiver type (father or mother).</div></div><div><h3>Results</h3><div>Higher parental education, better child oral health behaviours, lower perceived barriers, and greater self-efficacy were significantly correlated with reduced ECC risk. Conversely, higher cues to action were linked to increased ECC risk, indicating a reactive rather than preventive approach. Stratified analyses revealed differing patterns: among fathers, only education and oral health knowledge were significantly protective, whereas among mothers, child oral health behaviours, perceived barriers, and self-efficacy were also significant predictors.</div></div><div><h3>Conclusion</h3><div>Parental psychosocial factors substantially influence ECC risk, with distinct roles for fathers and mothers. These findings highlight the importance of considering caregiver gender in future research and oral health intervention design.</div></div><div><h3>Clinical relevance</h3><div>Family-centred, gender-specific interventions that address caregiver-specific beliefs and behaviours may improve ECC prevention strategies and help reduce oral health disparities in preschool-aged children.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100902"},"PeriodicalIF":3.2,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clarifying the Findings of Our Study on Large Language Models and Infective Endocarditis Prophylaxis","authors":"Paak Rewthamrongsris,&nbsp;Jirayu Burapacheep,&nbsp;Vorapat Trachoo,&nbsp;Thantrira Porntaveetus","doi":"10.1016/j.identj.2025.100887","DOIUrl":"10.1016/j.identj.2025.100887","url":null,"abstract":"","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100887"},"PeriodicalIF":3.2,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classic Publications in the Field of Dentistry: A Bibliometric Analysis","authors":"Yuh-Shan Ho ,&nbsp;Nikolaos Christidis","doi":"10.1016/j.identj.2025.100909","DOIUrl":"10.1016/j.identj.2025.100909","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>This bibliometric study aimed to identify and analyze the classic articles in the Web of Science category ‘Dentistry, Oral Surgery and Medicine,’ providing insights into the characteristics, citation patterns, and evolving trends that define the field's most influential publications.</div></div><div><h3>Methods</h3><div>Articles published between 1960 and 2020 were extracted from the Science Citation Index Expanded (SCI-EXPANDED) database. Classic articles were defined as those with ≥1000 citations as of the end of 2024. Bibliometric indicators such as total citations (<em>TC₂₀₂₄</em>), citations in 2024 (<em>C₂₀₂₄</em>), citations per publication (<em>CPP₂₀₂₄</em>), and authorship patterns were analyzed. Citation trajectories, author keywords, and institutional and international collaborations were also assessed.</div></div><div><h3>Results</h3><div>A total of 42 classic articles were identified. These publications were most frequently produced in the 1990s and 2000s and originated predominantly from the USA and Sweden. The University of North Carolina and the University of Gothenburg were particularly prominent. Periodontology, implantology, dental materials, and oral epidemiology were common themes. Articles such as Socransky et al. and Schiffman et al. demonstrated both sustained and recent citation influence. Word frequency analysis highlighted topics such as plaque, periodontal disease, and classification systems. Citation histories revealed diverse trajectories, including delayed recognition and rapid recent influence.</div></div><div><h3>Conclusion</h3><div>Classic articles in dental research reflect the field’s shift toward evidence-based practice, interdisciplinary collaboration, and public health relevance. By mapping these highly cited works, this study provides a clearer understanding of the factors contributing to long-term scientific impact in dentistry, oral surgery, and medicine.</div></div><div><h3>Clinical relevance</h3><div>This study identifies highly cited publications that have shaped clinical practice in periodontology, implantology, temporomandibular disorders, wound healing, and oral-systemic health. These works continue to guide diagnostics, treatment planning, and public health strategies, highlighting the lasting impact of foundational research and the importance of interdisciplinary, evidence-based approaches in dentistry.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 5","pages":"Article 100909"},"PeriodicalIF":3.2,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}