International dental journal最新文献

{"title":"Effects of Immediate Dentin Sealing and Quercetin on the Fracture Strength of Ceramic Inlays in Premolars of Daibetics.","authors":"Fereshteh Shafiei, Zahra Jowkar, Samaneh Sarrafi, Mahshid Mohammadi-Bassir","doi":"10.1016/j.identj.2026.111089","DOIUrl":"10.1016/j.identj.2026.111089","url":null,"abstract":"<p><strong>Aim: </strong>This in vitro study evaluated the effects of immediate dentin sealing (IDS) versus delayed dentin sealing (DDS), dentin pretreatment with quercetin (Qu), and their combination on the fracture strength (FS) of diabetic and non-diabetic premolars restored with ceramic inlays after thermomechanical aging.</p><p><strong>Methods: </strong>Forty-eight extracted premolars from diabetic individuals and forty-eight from non-diabetic individuals were collected and prepared for standardized MOD lithium disilicate ceramic inlays. Each category of teeth was divided into four groups according to the cementation technique (IDS or DDS) and the presence or absence of Qu pretreatment during inlay cementation. For IDS, the same adhesive was applied in combination with a flowable composite. All restored premolars underwent thermomechanical aging followed by FS testing under axial compression. Data were analyzed using three-way ANOVA and t-tests (P = .05).</p><p><strong>Results: </strong>Technique, Qu treatment, diabetes mellitus (DM), and the interactions between DM and Qu (P = .004) and between DM and technique (P = .021) were significant. The interaction among all three factors and the interaction between technique and Qu were not significant. In all groups except DDS/Qu, diabetic premolars exhibited lower FS than non-diabetic premolars (P < .001). IDS resulted in significantly higher FS in both tooth types (P < .001). The positive effect of Qu pretreatment was observed only in diabetic premolars (P < .001).</p><p><strong>Conclusion: </strong>In diabetic premolars, IDS and Qu pretreatment substantially enhanced the FS of teeth restored with ceramic inlays, with the greatest improvement observed when both were combined. In non-diabetic premolars, a significant improvement was observed only with IDS.</p><p><strong>Clinical relevance: </strong>Diabetes-related changes in dentin may compromise the performance of adhesive restorations. Understanding the effects of dentin sealing techniques and the potential benefits of Qu may help improve the durability of indirect restorations in patients with diabetes.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"111089"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13571600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Intracellular Lysate Sustained-Release Nanohydrogel Promotes Osteogenesis and Angiogenesis.","authors":"Fangxuan Hu, Dongdong Xu, Wenjia Hu, Xiaohui Hu, Ruoxi Du","doi":"10.1016/j.identj.2026.109765","DOIUrl":"10.1016/j.identj.2026.109765","url":null,"abstract":"<p><strong>Introduction and aims: </strong>Nanomaterials hold great promise for applications in bone tissue engineering. Dental pulp stem cell (DPSC) lysate, as a kind of intracellular lysate, has attracted increasing attention as a bioactive, cell-free therapeutic component in bone tissue engineering. Zeolitic imidazolate framework-8 (ZIF-8), a zinc-based MOF with sodalite topology, features high surface area, porosity and stability under physiological conditions. Its excellent biocompatibility, pH-responsive degradability and drug-loading capacity make it widely applicable in drug delivery.</p><p><strong>Methods: </strong>In this study, we developed a strategy for delivering DPSC lysate by encapsulating it within Poloxamer hydrogel and ZIF-8 nanoparticles, successfully synthesising IV@ZIF-8@Poloxamer Hydrogel (INZG).</p><p><strong>Results: </strong>The resulting INZG exhibited excellent biocompatibility and supported cell viability. In vitro and vivo experiments demonstrated that INZG possessed outstanding osteogenic and angiogenic properties, promoting bone and blood vessel formation via activation of the P38/MAPK and PDGFRβ/PI3K/AKT signalling pathways, respectively.</p><p><strong>Conclusion: </strong>In summary, this study is the first to propose that INZG possess excellent biocompatibility and bioactive functions that promote both osteogenic and angiogenic differentiation.</p><p><strong>Clinical relevance: </strong>This study provides a safe and effective new strategy for the treatment of various bone defects and lays a theoretical foundation for the development of vascularised bone scaffolds.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"109765"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13507757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ferroptosis-Regulated Osteoblasts Under Compression Via GPX4/RUNX1 Pathway.","authors":"Mengjia Wang, Changyun Sun, Hongrui Liu, Xin Zhang, Jiahao Zhang, Qiaohui Ying, Yongwei Wu, Zichen Zhao, Fanke Wang, Jie Guo","doi":"10.1016/j.identj.2026.109803","DOIUrl":"10.1016/j.identj.2026.109803","url":null,"abstract":"<p><strong>Background: </strong>The adaptive remodelling of alveolar bone ensures the effectiveness and stability of orthodontic tooth movement (OTM), but how to accurately regulate the remodelling of alveolar bone is the focus of orthodontic research. Ferroptosis plays an important role in bone remodelling.</p><p><strong>Methods: </strong>Immunohistochemical analysis was employed to assess the expression of ferroptosis-related proteins GPX4 and ACSL4 to investigate ferroptosis induction on the compressive side during orthodontic treatment. Subsequently, proteomic analysis was conducted on GPX4 knockdown MC3T3-E1 cells to identify potential transcription factors. Dual luciferase and ChIP-qPCR assays were utilised to examine the GPX4 promoter region. Furthermore, the impact of RUNX1 modulation was evaluated through both in vitro and in vivo experiments.</p><p><strong>Results: </strong>The application of compressive force led to a significant decrease in GPX4 expression in alveolar bone, suggesting that ferroptosis contributes to osteoblast death under compressive force. Analysis using the JASPAR database revealed that RUNX1, a transcription factor associated with RUNt, may play a crucial role in regulating glutathione peroxidase 4 (GPX4), a key marker of ferroptosis during orthodontic tooth movement (OTM). ChIP-qPCR results confirmed the binding of RUNX1 to the GPX4 promoter region, and treatment with the RUNX1 agonist kartogenin effectively rescued the osteogenic loss induced by GPX4 reduction. Modulation of GPX4 levels did not reverse the decrease in RUNX1 expression. Additionally, examination of osteogenic changes in MC3T3-E1 cells under compressive force following kartogenin treatment demonstrated that increased levels of RUNX1 contributed to increasing osteogenic levels under compressive force conditions.</p><p><strong>Conclusion: </strong>Our findings suggest that the RUNX1/GPX4 signalling axis may be a potential therapeutic target during orthodontic tooth movement that can promote alveolar bone remodelling by inhibiting ferroptosis in OTM.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"109803"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13519634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental Professionals' Knowledge of Oral Health in Chronic Kidney Disease: Exploratory Survey.","authors":"Reinhard Chun Wang Chau, Prakash Gudsoorkar, Isabella Lerma, Sompop Bencharit, Fernando Neves Hugo, Abhijit V Kshirsagar, Edgar Lerma, Ryan Lee, Daniel Croley, Sujay A J Mehta, Sabine Karam, Lakshman Samaranayake, Priyanka Gudsoorkar","doi":"10.1016/j.identj.2026.109815","DOIUrl":"10.1016/j.identj.2026.109815","url":null,"abstract":"<p><strong>Introduction and aims: </strong>The bidirectional relationship between periodontitis and chronic kidney disease (CKD) underscores the importance of oral health in CKD management. However, interdisciplinary collaboration between dental and nephrology professionals remains limited. This study assessed dental professionals' knowledge, clinical experiences, referral patterns, perceived barriers, and attitudes towards integrated oral-renal care.</p><p><strong>Methods: </strong>A cross-sectional web-based survey was conducted internationally in Asia, North America, Africa, Europe, South America, and Australia from November 2025 to February 2026. The instrument explored demographics, clinical exposure to CKD/end-stage kidney disease patients, self-assessed knowledge and confidence, referral/communication patterns, barriers to coordination, and interest in interdisciplinary protocols. Data from 89 valid responses were analysed using descriptive and inferential statistical methods.</p><p><strong>Results: </strong>Respondents were predominantly experienced practitioners (74.2% with >10 years of practice; 67.4% had treated CKD patients; 53.9% dialysis patients). The self-assessed composite knowledge-and-confidence score for oral-renal interactions was moderate (mean 7.67/12). Referrals from nephrologists and direct interdisciplinary communication were infrequent. Primary barriers included a lack of a clear point of contact (51.7%) and a lack of shared patient records (50.6%). Oral health was rated as very or moderately important in CKD management by 94.4% of respondents, and 100% expressed definite or possible interest in formal interdisciplinary care protocols.</p><p><strong>Conclusions: </strong>Despite moderate self-assessed knowledge and substantial clinical exposure, structural and systems-level barriers appear to impede the integration of oral-renal care. Dental professionals nevertheless demonstrate near-universal motivation for interdisciplinary collaboration and strong interest in formal care protocols.</p><p><strong>Clinical relevance: </strong>Findings highlight the need for educational initiatives, standardized referral pathways, interoperable records, and policy support to advance multidisciplinary care for CKD patients.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"109815"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13508613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontitis Exacerbates Insulin Resistance via Gut Barrier Dysfunction and TLR4/NF-κB Activation.","authors":"Lanlan Jiang, Yuxiao Huang, Shimin Zhang, Xuelian Li, Feifei Mo, Chunyan Huang, Renchuan Tao","doi":"10.1016/j.identj.2026.109818","DOIUrl":"10.1016/j.identj.2026.109818","url":null,"abstract":"<p><strong>Introduction and aims: </strong>Periodontitis and type 2 diabetes mellitus (T2DM) are interrelated, potentially linked through intestinal barrier dysfunction. Yet, whether their comorbidity is associated with worsened barrier integrity and how this relates to insulin resistance remain unclear. This study examined associations between periodontitis, gut barrier disruption, Toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) activation, and metabolic parameters in a T2DM mouse model.</p><p><strong>Methods: </strong>Twenty-four C57BL/6 mice were randomised into 4 groups (n = 6): healthy control, chronic periodontitis, T2DM without periodontitis (DNP), and T2DM with periodontitis (DP). Glucose homeostasis was assessed by measuring fasting blood glucose and the area under the curve of oral glucose tolerance tests and insulin tolerance tests. The colonic barrier's biological, chemical, physical, and immune properties were evaluated using 16S ribosomal RNA sequencing, haematoxylin and eosin staining, transmission electron microscopy, reverse transcription polymerase chain reaction, Western blotting, and flow cytometry. Furthermore, serum insulin and inflammatory cytokines were quantified by enzyme-linked immunosorbent assay.</p><p><strong>Results: </strong>The composition of both the periodontal and faecal microbiota in the DP group was markedly different from that in the DNP group. In the DP group, transmission electron microscopy revealed severe damage to colonic mucosal ultrastructure; messenger RNA and protein expression levels of MUC2 and tight junctions (including occludin, claudin-1, and ZO-1) were significantly decreased; the proportion of regulatory T cells diminished, while Th17 cells increased, resulting in an imbalanced regulatory T-cell/Th17 ratio. Proinflammatory cytokines in intestinal tissues and serum were raised, whereas anti-inflammatory cytokines were decreased. Moreover, in the DP group, activation of the TLR4/NF-κB pathway was observed in intestinal tissue. Notably, levels of fasting blood glucose, serum insulin, and area under the curve for oral glucose tolerance tests and insulin tolerance tests were all higher in the DP group than in the DNP group.</p><p><strong>Conclusions: </strong>Periodontitis is related to intestinal barrier disruption, TLR4/NF-κB signalling activation, and worsened metabolic parameters in T2DM mice.</p><p><strong>Clinical relevance: </strong>These findings may establish periodontitis as a potent driver of gut barrier dysfunction, systemic inflammation, and insulin resistance, highlighting its profound impact on metabolic health.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"109818"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148880341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sema3A Restores Bone Homeostasis in Peri-Implantitis by Activating Osteoblasts and Suppressing Osteoclasts via PI3K/AKT.","authors":"Chenjiang He, Fang Dai, Jingting Wu, Libin Deng, Meixiu Jiang, Yuting Yang, Li Li, Fancheng Xu, Li Song","doi":"10.1016/j.identj.2026.111100","DOIUrl":"10.1016/j.identj.2026.111100","url":null,"abstract":"<p><strong>Background: </strong>Peri-implantitis, a major cause of implant failure, is driven by disrupted bone homeostasis. Semaphorin 3A (Sema3A) bidirectionally regulates bone remodelling, yet its role in peri-implantitis remains poorly defined. This study aimed to elucidate the mechanisms by which Sema3A modulates bone homeostasis in peri-implantitis.</p><p><strong>Materials and methods: </strong>Single-cell transcriptomic analysis (GSE171213) was performed on a periodontitis-derived periodontal tissue dataset to characterize bone-related cell communication. A murine peri-implantitis model was established via silk ligation, and bone loss was assessed by micro‑CT. In vitro, MC3T3-E1 osteoblasts were exposed to Porphyromonas gingivalis LPS and transduced with Sema3A‑overexpressing lentivirus. Proliferation, migration, osteogenic differentiation, and the PI3K/AKT pathway were evaluated. An osteoblast-osteoclast coculture system was used to assess osteoclastogenesis.</p><p><strong>Results: </strong>Reanalysis of a periodontitis-derived single-cell dataset showed reduced SEMA3A expression and a lower osteogenic-lineage score in sparsely represented osteogenic-lineage-like cell populations under inflammatory conditions. Peri‑implantitis mice exhibited reduced SEMA3A, decreased P1NP, elevated CTX‑1, and significant bone loss (P < .05). Sema3A overexpression significantly rescued LPS‑impaired osteoblast proliferation, migration, and osteogenic differentiation (P < .01). RNA‑seq identified PI3K/AKT pathway enrichment; Sema3A increased phosphorylated AKT, and the PI3K/AKT inhibitor Palomid 529 abolished these protective effects. In coculture, Sema3A‑overexpressing osteoblasts suppressed osteoclast differentiation, reducing TRAP⁺ cells, Nfatc1, and Ctsk (P < .01).</p><p><strong>Conclusions: </strong>Sema3A restores osteoblast function under inflammatory conditions, partly through PI3K/AKT signalling, and suppresses osteoclast differentiation indirectly in an osteoblast-osteoclast coculture system. Notably, Sema3A overexpression alone had no effect under normal conditions but specifically counteracted inflammatory damage. These findings suggest Sema3A is a potential therapeutic target for peri‑implantitis.</p><p><strong>Clinical significance: </strong>Sema3A simultaneously enhances osteogenesis and inhibits bone resorption specifically under inflammatory conditions, while preserving basal bone homeostasis, thereby representing a targeted bone-protective strategy for peri-implantitis that may improve implant survival and reduce the need for invasive surgical interventions.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"111100"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13571595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of LLMs for Automated Dental-to-Medical Consult Letter Generation: Comparative Study.","authors":"Dareen Eom, Kyeol Koh, Howon Chung, Kwangsoo Kim, Sang-Hwa Lee","doi":"10.1016/j.identj.2026.111088","DOIUrl":"10.1016/j.identj.2026.111088","url":null,"abstract":"<p><strong>Introduction and aims: </strong>For dental patients with systemic diseases, multidisciplinary care via referral letters is essential for clinical safety. This study evaluated the clinical feasibility and quality of dental-to-medical referral letters generated by Large Language Models (LLMs).</p><p><strong>Methods: </strong>Using 153 paired datasets, three LLMs - Gemini-2.5-Pro, GPT-5 and MedGemma - generated referral letters via a standardised prompting framework. Two dental clinicians performed a blinded assessment across nine sub-criteria covering content, style and correctness. GPT-5 also performed an automated evaluation. Statistical significance was analysed using Friedman and Wilcoxon signed-rank tests with Holm correction.</p><p><strong>Results: </strong>In the human clinical evaluation, Gemini-2.5-Pro achieved the highest overall performance (TOTAL mean SCORE: 2.9487 with a bootstrap 95% confidence interval [CI] of 2.9345-2.9606), significantly outperforming GPT-5 (2.8818 with 95% CI of 2.8613-2.9008) and MedGemma (2.8613 with 95% CI of 2.8338-2.8865) (P < .05). While GPT-5 showed high clarity in systemic problem descriptions, MedGemma excelled in structural adherence. The overall performance difference between GPT-5 and MedGemma was not statistically significant (P = .3519). Inter-rater reliability was strong in the prompt search dataset (QWK: 0.7175) but lower in the independent test dataset (QWK: 0.1505), reflecting the subjective nature of clinical document assessment; therefore, final human scores were reported as average ratings from two blinded clinicians with bootstrap confidence intervals. Notably, GPT-5's self-evaluation results deviated from human judgment, exhibiting potential model-based bias.</p><p><strong>Conclusion: </strong>This preliminary study suggests the potential of Gemini-2.5-Pro for automated consult letter generation, though the low test-set inter-rater reliability (QWK: 0.1505) highlights the subjective complexity of clinical text. To integrate these assistive prototypes into routine clinical application, more systematic studies are required.</p><p><strong>Clinical relevance: </strong>Integrating LLMs offers a promising approach to assisting with dental-to-medical referrals, presenting a potential future benefit of reducing administrative workloads and enabling healthcare providers to focus on safe, empathetic patient care.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"111088"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13571579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Dynamic and Static Navigated Endodontic Microsurgery Using Single Vertical Incision: A Retrospective Study.","authors":"Xiaoxing Li, Lishan Huang, Yufei Li, Siyu Li, Xin Li, Xuechao Yang","doi":"10.1016/j.identj.2026.109822","DOIUrl":"10.1016/j.identj.2026.109822","url":null,"abstract":"<p><strong>Background: </strong>Dynamic navigation (DN) and static navigation (SN) in endodontic microsurgery (EMS) have been shown to improve the precision of osteotomy and root-end resection (RER). However, the impact of minimal incisions on DN- and SN-guided EMS remains unclear. This study assessed the accuracy of DN and SN in EMS performed via a single vertical incision at the apex (SVIA), and identified technique-specific accuracy predictors.</p><p><strong>Methods: </strong>A retrospective analysis included 60 teeth treated with SVIA EMS, comprising 30 osteotomies and RERs each in the SN and DN groups. Preoperative variables - sex, age, tooth position, arch type, drilling depth, lesion size, and buccal bone integrity - were recorded. Postoperative cone-beam computed tomography (CBCT) scans were superimposed with preoperative plans to evaluate accuracy. Group comparisons used independent t-tests or Mann-Whitney U tests (α = 0.01); general linear model examined the interaction effects between the technique and preoperative variables on accuracy; multivariate regression (α = 0.017) identified independent predictors within each group.</p><p><strong>Results: </strong>No significant differences in accuracy parameters were observed between DN and SN (P > .01). Interaction effects were nonsignificant (P > .05). Intragroup analysis indicated that for DN, a lesion diameter > 9 mm predicted increased resection angle deviation (RAD) (B = 3.13, P < .017), while for SN, posterior tooth location predicted reduced RAD (B = -5.80, P < .017).</p><p><strong>Conclusions: </strong>DN and SN exhibited comparable overall accuracy in SVIA EMS. However, DN was less accurate in cases with large lesions, whereas SN achieved higher accuracy in posterior regions. These preliminary findings support the evidence-based selection of guidance techniques according to anatomic specifics in SVIA EMS.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"109822"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13571232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structured Microskill Stepwise Progression for Undergraduate Tooth Extraction: A Randomized Mixed-Methods Study.","authors":"Zongxi Wu, Mingyue Wang, Xueting Luo, Xiangqi Liu, Le Yang, Siyong Gao, Sien Zhang, Guangsen Zheng","doi":"10.1016/j.identj.2026.111097","DOIUrl":"10.1016/j.identj.2026.111097","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate whether a structured microskill stepwise progression model improves procedural competence and reduces performance variability in undergraduate tooth extraction training compared with traditional apprenticeship-based teaching.</p><p><strong>Methods: </strong>This randomized mixed-methods pilot study allocated 40 fifth-year dental students (1:1) to traditional apprenticeship teaching or a microskill stepwise progression model during an 8-week oral surgery rotation. The intervention divided tooth extraction into nine stages, requiring five targeted observations and five successful supervised performances before progression. End-of-rotation competence was assessed using a modified Direct Observation of Procedural Skills (DOPS) scale by two blinded examiners. Between-group differences and score variability were analysed using Welch's t test and the F-test. Questionnaires and qualitative feedback explored learner and instructor perceptions.</p><p><strong>Results: </strong>Baseline theoretical examination scores were comparable between groups. Inter-rater reliability for the total modified DOPS scores was good (ICC = 0.86; 95% CI, 0.74-0.93; P < .001). The intervention group achieved higher modified DOPS scores than the control group (94.60 ± 3.97 vs 88.25 ± 6.41; mean difference, 6.35; 95% CI, 2.94-9.76; P < .001; Cohen's d = 1.19) and lower score variability (F = 2.616; P = .042), with a narrower score range (87-100 vs 75-96). Qualitative findings suggested clearer progression and more consistent competence development. Questionnaire findings were exploratory; four item-level differences remained significant after Benjamini-Hochberg correction.</p><p><strong>Conclusions: </strong>The microskill stepwise model was associated with improved tooth extraction performance and reduced variability in assessed procedural competence compared with traditional teaching. This mastery-oriented approach may support more structured supervision and more consistent educational readiness in oral surgery training.</p><p><strong>Clinical relevance: </strong>This framework helps educators organize undergraduate tooth extraction training using procedure-specific stages, supervised-performance thresholds, and documented progression criteria. It may promote consistent standards and transparent entrustment decisions, but should be adapted to local case availability and supervisor workload.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 5","pages":"111097"},"PeriodicalIF":5.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13571219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of concern: \"Prompt-Driven ChatGPT Carbon Calculator for Dental Practices: Estimation and Tailored Improvement Strategies\" [International Dental Journal, Volume 76, Issue 1, February 2026, 103979].","authors":"","doi":"10.1016/j.identj.2026.109665","DOIUrl":"10.1016/j.identj.2026.109665","url":null,"abstract":"","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 4","pages":"109665"},"PeriodicalIF":5.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13277421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}