International dental journal最新文献

{"title":"Understanding Data Drift in Dental AI.","authors":"Priyanka Gudsoorkar","doi":"10.1016/j.identj.2025.103937","DOIUrl":"https://doi.org/10.1016/j.identj.2025.103937","url":null,"abstract":"","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"103937"},"PeriodicalIF":3.7,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation of Biocompatibility between Conventional and Computer-Aided Design/Computer-Aided Manufacturing Dental Polymers Using a Golden Hamster Model.","authors":"Xia Wei, Huakun Shangguan, Ling Wu, Linjuan Gao, Yu Pan, Yiling Cheng, Hui Cheng, Yinghui Wang","doi":"10.1016/j.identj.2025.103958","DOIUrl":"https://doi.org/10.1016/j.identj.2025.103958","url":null,"abstract":"<p><strong>Introduction and aims: </strong>Computer-aided design/computer-aided manufacturing (CAD/CAM) dental polymers exhibit superior mechanical properties compared to conventional ones, but their biocompatibility remains controversial. This study aimed to systematically compare in vivo biocompatibility of conventional and CAD/CAM dental polymers using a golden hamster model.</p><p><strong>Methods: </strong>Six dental polymers were evaluated: conventional (VAR) and CAD/CAM (OP) polymethylmethacrylate (PMMA) denture base materials; conventional bis-acrylic (PT) and CAD/CAM PMMA (DM) interim restorative materials; pressed (PB) and CAD/CAM (CB) polyetheretherketone (PEEK) prosthetic framework materials, with polypropylene as control. Disk specimens (n = 6) were sutured in golden hamster buccal pouches for 14- and 28-day mucosal irritation tests. Systemic and local biocompatibility was assessed through hepatic/renal function tests, histopathology (HE staining), apoptosis detection (TUNEL), and apoptosis-related molecular analysis (RT-qPCR and Western blot) of buccal pouch mucosa, liver, and kidney tissues.</p><p><strong>Results: </strong>All groups showed normal physiological conditions throughout the study period. Histological examination revealed normal tissue morphology in all tested organs, with only mild or no mucosal irritation observed. Transient fluctuations were observed in ALB, A/G, BUN and TP at 14 days, but the differences between groups tended to stabilize at 28 days. The results of TUNEL and RT-qPCR demonstrated comparable results across all groups. The expression of Bax and Bcl-2 proteins in buccal pouch mucosa of VAR group were elevated at 28 days compared to 14 days, while only Bax protein was elevated in PB group (P < .05). The expression level of pro Caspase-3 protein in the liver tissue of VAR group and PT group decreased at 28 days (P < .05).</p><p><strong>Conclusions: </strong>Both conventional and CAD/CAM dental polymers exhibited acceptable in vivo biocompatibility, but CAD/CAM dental polymers showed superior temporal stability.</p><p><strong>Clinical relevance: </strong>The superior temporal stability in the in vivo biocompatibility profile of CAD/CAM dental polymers supports their clinical preference for long-term prosthodontic applications.</p>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"103958"},"PeriodicalIF":3.7,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibroblast Ferroptosis Aggravates Inflammation Response in Dental Pulpitis","authors":"Xiaohui Lv ,&nbsp;Xuan Chen ,&nbsp;Li Lin,&nbsp;Yang Li,&nbsp;Liecong Lin,&nbsp;Bingtao Wang,&nbsp;Xiaoshi Chen,&nbsp;Qianzhou Jiang","doi":"10.1016/j.identj.2025.103927","DOIUrl":"10.1016/j.identj.2025.103927","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Pulpitis, an inflammatory disorder of dental pulp tissue, represents a common clinical challenge in endodontic pathology. Emerging evidence implicates ferroptosis, a newly recognised iron-dependent form of regulated cell death, in the pathogenesis of inflammatory conditions. However, its functional significance in pulpal inflammation remains poorly characterised. The objectives of this study were to (1) investigate the functional significance of ferroptosis in pulpitis; (2) identify the cell type undergoing ferroptosis; and (3) provide novel insights into therapeutic strategies.</div></div><div><h3>Methods</h3><div>We conducted an investigation combining clinical specimen analysis (human pulp tissues), single-cell transcriptomic profiling and experimental mice models. Co-localisation staining and single-cell RNA sequencing data were analysed to identify the cell type that underwent ferroptosis. Immunofluorescence co-localisation studies and scRNA-seq data analysis were used to identify cellular populations undergoing ferroptosis. The susceptibility of dental pulp fibroblasts to ferroptosis in an inflammatory condition was investigated using <em>in vitro</em> cell cultures.</div></div><div><h3>Results</h3><div>Our findings demonstrate that dental pulp fibroblasts undergo ferroptosis in pulpitis. Pulpitis-induced pro-inflammatory immune responses were characterised by a profound elevation of fibroblast-derived interleukin-6 <em>(</em>IL-6) and interleukin-1β (IL-1β), which was attenuated by ferroptosis inhibition. Pulp inflammation is alleviated by inhibition of fibroblast ferroptosis.</div></div><div><h3>Conclusion</h3><div>This study reveals a previously unrecognised mechanistic link between fibroblast ferroptosis and pulpal immunopathology, providing novel insights into therapeutic strategies for vital pulp preservation.</div></div><div><h3>Clinical Significance</h3><div>The identification of fibroblast ferroptosis as a driver of pulp inflammation and inhibition of inflammation by ferroptosis inhibitors Ferrostatin-1 (Fer-1) in mice models offer potential alternative therapeutic strategies for vital pulp preservation.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"Article 103927"},"PeriodicalIF":3.7,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Auxiliary Devices on the Accuracy of Complete‑Arch Implant Digital Impressions: An in Vitro Study","authors":"Hao Liu ,&nbsp;Xiangting Zhang ,&nbsp;Ya Gao ,&nbsp;Mengyao Li ,&nbsp;Zhe Qu ,&nbsp;Jiaming Zhao","doi":"10.1016/j.identj.2025.103950","DOIUrl":"10.1016/j.identj.2025.103950","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the effectiveness of the auxiliary device in acquiring implant and soft tissue data using intraoral scanning and its influence on the accuracy of digital impressions for edentulous implants.</div></div><div><h3>Methods</h3><div>Three standardized implant models for edentulism, categorized as 2-4, 2-5 and 2-4-6, were designed and printed based on the distribution of implants. Various auxiliary devices were designed for each model, and an artificial gingiva with cube-like marking points was created to test the completeness of soft tissue information capture. The models were scanned using an extraoral model scanner to obtain accurate baseline data. Intraoral scans (Trios 4) were performed before and after adding auxiliary devices. The scan data were evaluated using inspection software. The linear distances of center point of upper plane between scan body was calculated. The Shapiro–Wilk normality test, independent-samples t test, and Mann–Whitney nonparametric test were used for statistical analysis. Statistical significance was set at α = 0.05.</div></div><div><h3>Results</h3><div>The trueness and precision of most loci improved with the inclusion of auxiliary devices, surpassing their counterparts without such devices. Notably, trueness advanced in: the 2-4 group using 2.5-mm-wide smooth-surface (W2.5-S) for the longest span (#14-#24) [decreased from (0.123 ± 0.034) mm to (0.081 ± 0.033) mm]; the 2-5 group employing 2.5-mm-wide cube-like (W2.5-C) and hemisphere-like(W2.5-H) devices for the longest span (#15-#25), (decreased from [0.155 ± 0.061] mm to [0.028 ± 0.017] mm and [0.035 ± 0.019] mm); and the 2-4-6 group with W2.5-C and W2.5-H devices for loci #16-#24 [decreased from (0.091 ± 0.056) mm to (0.055 ± 0.033 mm and (0.054 ± 0.041) mm] and #16-#26 (decreased from [0.148 ± 0.112] mm to [0.088 ± 0.041] mm and [0.084 ± 0.047] mm) (<em>P &lt; .</em>05). Adding the devices did not affect the root-mean-square values of the soft tissue marker points.</div></div><div><h3>Conclusions</h3><div>The use of auxiliary devices enhances the accuracy of digital impressions for edentulous implant restorations obtained using intraoral scanners while also capturing complete soft tissue information.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"Article 103950"},"PeriodicalIF":3.7,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Health-Related Quality of Life among Asylum Seekers and Refugees: A Systematic Review","authors":"Win Myat Phyo ,&nbsp;Duangporn Duangthip ,&nbsp;Palinee Detsomboonrat","doi":"10.1016/j.identj.2025.103956","DOIUrl":"10.1016/j.identj.2025.103956","url":null,"abstract":"<div><div>Asylum seekers and refugees (ASRs) often experience poorer oral health outcomes than the most disadvantaged populations in their host countries. Limited information is available on the oral health-related quality of life (OHRQoL) of ASRs. This systematic review synthesized existing research on OHRQoL among ASRs populations. A systematic search was conducted in EBSCOhost (Dentistry &amp; Oral Sciences Source), PubMed, Scopus, and Google Scholar Advanced Search, without language restrictions. Two researchers independently performed the study selection and data extraction, with any discrepancies resolved through discussion with a third researcher. The citations and references of the included studies were also scrutinized to identify additional relevant literature. The inclusion criteria encompassed experimental or observational studies that evaluated OHRQoL among ASRs using at least one OHRQoL tool. Out of 141 identified, 10 studies met the inclusion criteria. All included studies primarily examined refugee populations, and none focused exclusively on asylum seekers without refugee status. These studies, published between 2014 and 2025, were conducted in United States, Turkey, India, New Zealand, Norway, Jordan, Northern Greece, Austria, and South Australia, with 1844 participants aged 4 to 76 years. Five out of ten studies (50%) measured OHRQoL by using the Oral Health Impact Profile-14. Most of the refugees were from Syria, and Arabic-language OHRQoL tools were the most commonly used (33.3%, 7/21). Physical pain domain emerged as the most frequently impacted domain of OHRQoL, ranging from 28.8% to 70.4%, across the included studies. This review highlights that refugees experience substantial impairments in OHRQoL, with the physical pain domain being the most affected. No studies on OHRQoL focusing exclusively on asylum seekers without refugee status are currently available, highlighting the need for future research to address this evidence gap.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"Article 103956"},"PeriodicalIF":3.7,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibulin1 as a Novel Target for Promoting the Biological Function of Bone Marrow Mesenchymal Stem Cells and Implant Osseointegration in Diabetic Patients","authors":"Yuqing Zhang ,&nbsp;Fangwen Jia ,&nbsp;Kangya Li ,&nbsp;Yuwei Yan ,&nbsp;Xiu Liu ,&nbsp;Wei Geng ,&nbsp;Chao Liang","doi":"10.1016/j.identj.2025.103928","DOIUrl":"10.1016/j.identj.2025.103928","url":null,"abstract":"<div><h3>Background and aims</h3><div>Type 2 diabetes mellitus (T2DM) is recognized as a significant risk factor affecting implant osseointegration. Our previous proteomic study revealed that Fibulin1 (FBLN1) was significantly downregulated in the alveolar bone marrow mesenchymal stem cells (BMSCs) of T2DM patients with implant failure. This study aimed to verify the effects of FBLN1 on the biological function of BMSCs and implant osseointegration in T2DM patients to identify novel intervention targets for the future development of clinical treatments.</div></div><div><h3>Materials and methods</h3><div>In in vitro experiments, FBLN1 was overexpressed in BMSCs from diabetic patients via lentiviral transduction. The effects of FBLN1 on the biological functions of BMSCs were assessed via a CCK8 assay, a wound healing assay, a Transwell assay, alkaline phosphatase staining, alizarin red staining, and subcutaneous osteogenesis analysis using nude mice. The molecular mechanism by which FBLN1 acts on BMSCs was verified via RT-qPCR and western blotting. In in vivo experiments, the effect of FBLN1 on implant osseointegration in diabetic GK rats through cell sheet–implant complexes was verified by microcomputed tomography and toluidine blue staining.</div></div><div><h3>Results</h3><div>FBLN1 was expressed in BMSCs at an early stage of the osteogenic process. CCK8, wound healing, and Transwell assays indicated that the overexpression of FBLN1 increased the proliferation and migration of BMSCs. Alkaline phosphatase staining, alizarin red staining and subcutaneous osteogenesis analysis revealed that the overexpression of FBLN1 enhanced the osteogenic differentiation of BMSCs, and RT-qPCR and western blotting revealed that FBLN1 affected this process through the FOXO1/RUNX2 signalling pathway. Microcomputed tomography and toluidine blue staining revealed that after the implantation of cell sheet–implant complexes in rats, overexpressing FBLN1 in BMSCs could restore the level of implant osseointegration in GK rats to a level similar to that in Wistar rats.</div></div><div><h3>Conclusions</h3><div>FBLN1 enhances the proliferation and migration of BMSCs from T2DM patients and promotes osteogenic function through the FOXO1/RUNX2 signalling pathway. Moreover, FBLN1 promotes implant osseointegration in diabetic GK rats, suggesting that FBLN1 is a novel target protein for increasing the success rate of dental implant surgery in T2DM patients.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"Article 103928"},"PeriodicalIF":3.7,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Oral Health, Oral Behaviours, and Oral Healthcare Utilisation Among Indian Migrants Living in the Netherlands","authors":"Amandeep Pabbla ,&nbsp;Charles Agyemang ,&nbsp;Irene Aartman ,&nbsp;Denise Duijster","doi":"10.1016/j.identj.2025.103946","DOIUrl":"10.1016/j.identj.2025.103946","url":null,"abstract":"<div><h3>Objectives</h3><div>The aim of this study was to assess perceptions on the role of migration on oral health, oral health behaviours, and oral healthcare utilisation among Indian migrants living in the Netherlands.</div></div><div><h3>Design</h3><div>Seven focus group discussions, with a total of 27 participants, were conducted among Indian migrants, using a semistructured interview guide. Interviews were transcribed and data were analysed using an open coding method, based on Andersen’s behavioural model. Using directed content analysis, emerging themes were organised under the main Andersen’s healthcare model.</div></div><div><h3>Results</h3><div>The analysis resulted in six identified themes on changes perceived by Indian migrants in their oral health and oral health behaviours since migrating to the Netherlands, and in seven identified themes on changes perceived in their oral healthcare utilisation and identified barriers and facilitators with oral healthcare. Migrants reported shifts in product use, with some adopting Dutch oral hygiene routines while many also continued Ayurvedic practices. Positive dietary changes, such as reduced sugar consumption, were noted. Experiences with Dutch oral healthcare utilisation were mixed: some participants highlighted facilitators including practitioner honesty, fixed pricing, preventive orientation, and welcoming clinic environments, supported by dental insurance and recall systems. At the same time, barriers emerged, particularly related to limited communication, distrust in Dutch dentists, uncertainties about malpractice procedures, and challenges in navigating the referral system.</div></div><div><h3>Conclusion</h3><div>This research highlights the complex factors associated with oral health behaviours and dental utilisation among Indian migrants in the Netherlands, emphasising the need for comprehensive consideration of cultural, socioeconomic, and environmental factors in future studies and interventions.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"Article 103946"},"PeriodicalIF":3.7,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Substrate Stiffness Regulates the Osteogenesis of PDLSCs Via ERK-Mediated YAP Nuclear Translocation","authors":"Yuting Fu ,&nbsp;Yijie Wang ,&nbsp;Bo Cheng ,&nbsp;Rui Zou ,&nbsp;Wanting Wan","doi":"10.1016/j.identj.2025.103852","DOIUrl":"10.1016/j.identj.2025.103852","url":null,"abstract":"<div><h3>Objectives</h3><div>Periodontitis is an inflammatory disease and may lead to the progressive destruction of alveolar bone. Periodontal ligament stem cells (PDLSCs) exhibit significant regenerative potential, and their osteogenic differentiation is influenced by the biophysical microenvironment, particularly substrate stiffness. However, the mechanistic pathways through which stiffness modulates PDLSCs osteogenesis remain incompletely understood. This study aimed to elucidate the role of ERK1/2 and YAP signalling pathways in regulating PDLSCs osteogenic differentiation in response to substrate stiffness.</div></div><div><h3>Methods</h3><div>Gelatin methacryloyl (GelMA) hydrogels with varying stiffness were fabricated to culture PDLSCs. Cell viability, spreading, and osteogenic differentiation were evaluated through live/dead staining, immunofluorescence, qRT-PCR, Western blot analysis, and alizarin red staining. The involvement of ERK1/2 and YAP signalling pathways was investigated using specific inhibitors. An <em>in vivo</em> rat periodontitis model was developed to validate <em>in vitro</em> findings, with periodontal ligament stiffness and alveolar bone resorption assessed via nanoindentation and micro-computed tomography (micro-CT).</div></div><div><h3>Results</h3><div>PDLSCs cultured on stiffer substrates exhibited enhanced osteogenic differentiation, as evidenced by upregulated expression of osteogenic markers (RUNX2 and OCN) and increased mineralization. Stiff substrate promoted ERK1/2 phosphorylation and YAP nuclear translocation. Inhibition of ERK1/2 reduced YAP nuclear localization and suppressed osteogenic marker expression. <em>In vivo</em>, periodontitis-associated reductions in periodontal ligament stiffness correlated with decreased YAP nuclear translocation and significant alveolar bone resorption. YAP inhibition mirrored these effects, underscoring its critical role in osteogenesis.</div></div><div><h3>Conclusions</h3><div>Substrate stiffness regulates PDLSCs osteogenesis via ERK-mediated YAP nuclear translocation. These findings advance our understanding of the mechanotransduction mechanisms underlying PDLSCs differentiation and highlight potential therapeutic targets for periodontal regeneration.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"Article 103852"},"PeriodicalIF":3.7,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral–Systemic Health Burden and Dry Mouth as an Intermediary Factor: A Cross-Sectional Study in Singapore Nursing Homes","authors":"Sayaka Tada,&nbsp;Sarah Koh Mun Yee,&nbsp;Gabriel Lee Keng Yan,&nbsp;Tay Chong Meng,&nbsp;Sim Yu Fan,&nbsp;Clement Lai Wei Ming,&nbsp;Wong Mun Loke","doi":"10.1016/j.identj.2025.103934","DOIUrl":"10.1016/j.identj.2025.103934","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>This cross-sectional study aimed to assess the prevalence of oral and systemic health conditions among older adults in nursing homes (NHs) in Singapore and investigate associations between dry mouth and oral-systemic health factors.</div></div><div><h3>Methods</h3><div>Participants were selected through a stratified cluster sampling method across 8 NHs. Inclusion criteria included age ≥60 years and physical/cognitive ability to undergo oral screening. Data on systemic health (care dependence, malnutrition, multimorbidity, and polypharmacy) and oral health (dry mouth, oral hygiene, dentition, gingival and periodontal condition, and denture quality) were collected in 2024. Bivariate analyses (Mann-Whitney U test and chi-square test) were used to assess associations between dry mouth and other health parameters. Logistic regression models were conducted to examine independent associations with dry mouth. Statistical significance was set at <em>P</em> &lt; .05.</div></div><div><h3>Results</h3><div>A total of 173 NH residents completed oral assessments (mean age: 75.0 ± 9.1 years; 38% female). Systemic health concerns were prevalent: 75.7% were care-dependent, 80.9% were malnourished or at risk, and 84.1% had multimorbidity. Cardio-cerebrovascular diseases (CVD) were the most common disease category (76.4%). Oral health problems were also widespread: 63.6% showed clinical symptoms of dry mouth, 46.6% had poor oral hygiene, 50.8% had at least one untreated coronal and/or root caries, and 89.2% showed gingival inflammation. Multivariate analysis identified CVD (OR = 3.99) as a systemic factor significantly associated with dry mouth. Greater plaque accumulation (OR = 5.09) and root caries (OR = 1.93) were also independently associated with dry mouth.</div></div><div><h3>Conclusions</h3><div>This study provides the first comprehensive report on oral-systemic health burden in NH residents in Singapore. Dry mouth emerged as a potential intermediary factor linking systemic health conditions and dental deterioration. These findings underscore the importance of interprofessional care strategies to address dry mouth and its consequences in this vulnerable population. (292 words)</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"Article 103934"},"PeriodicalIF":3.7,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy in Diagnosing Periodontitis Using the AAP/EFP 2017 Classification","authors":"Hammam I. Fageeh ,&nbsp;Hytham N. Fageeh ,&nbsp;Wael I. Ibraheem ,&nbsp;Ashok Kumar Bhati ,&nbsp;Bashair Mohammed Wasli ,&nbsp;Hind Ali Abeery ,&nbsp;Elham Ali Tohari ,&nbsp;Lujain K. Mokli ,&nbsp;Shreefah M. Faris","doi":"10.1016/j.identj.2025.103907","DOIUrl":"10.1016/j.identj.2025.103907","url":null,"abstract":"<div><h3>Purpose</h3><div>In the 2017 periodontal classification, periodontitis was diagnosed based on stage, grade and extent. Periodontitis is diagnosed not only by periodontists but also by general dentists. Therefore, the study was conducted to determine and compare the accuracy of periodontists, postgraduate periodontal students, general dentists and undergraduate students in diagnosing the stage, grade, and extent of periodontitis.</div></div><div><h3>Method</h3><div>Four groups of examiners—periodontists, postgraduate periodontal students, general dentists, and undergraduate students (<em>n</em> = 10 each) were included in the study. Five documented periodontitis cases were sent to examiners to determine the stage, grade, and extent of periodontitis. Average score (for stage, grade and extent separately) and overall score (combined score of stage, grade, and extent) were obtained. Intergroup comparisons for staging, extent, and grade were performed using a one-way ANOVA. The correlation between different scores obtained by groups of examiners was assessed using the intraclass correlation coefficient (ICC). <em>P</em> &lt; .05 was considered statistically significant.</div></div><div><h3>Results</h3><div>Substantial agreement was observed for stage (ICC = 0.658) and overall score (ICC = 0.690). Agreement for grade and extent was moderate (ICC = 0.518) and fair (ICC = 0.273), respectively. Significant substantial agreement between periodontists and postgraduates with the assessment of stage (ICC = 0.756) and overall score (ICC = 0.698) was found. For the overall score, periodontists (mean 1.74 ± 0.34) and postgraduates (mean 1.48 ± 0.391) performed better. Undergraduate students (mean 1.42 ± 0.25) performed better than general dentists (mean 1.40 ± 0.45).</div></div><div><h3>Conclusion</h3><div>Periodontists performed better than postgraduate students, undergraduates and general dentists. Undergraduates performed better than general dentists.</div></div><div><h3>Clinical relevance</h3><div>Correct diagnosis is critical for providing the correct treatment plan for treating the disease. Education and training can result in accurate diagnosis of the stage, grade, and extent of periodontitis, thereby providing treatment accordingly.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"75 6","pages":"Article 103907"},"PeriodicalIF":3.7,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}