{"title":"Comparison of lipid profile in physically trained adults and sedentary adults","authors":"S. Pawar","doi":"10.21746/IJBIO.2017.08.004","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.08.004","url":null,"abstract":"The incidence of diseases like angina pectoris, myocardial infarction, hypertension and cerebrovascular is increasing nowadays. The high blood lipid level is found to be the main cause of atherosclerosis. Present study is undertaken with the aim to evaluate the effect of physical training on BMI, Waist-hip ratio and lipid profile. Our research is focussed to study the Effect of Physical Training on Serum Lipids in physically trained adults and sedentary adults. To compare lipid profile between physically trained adult and sedentary adult. The study was conducted on 50 male physically trained adults and 50 male sedentary adults in the age group between 30-40 years. Following parameters were evaluated: Total cholesterol, Triglycerides, HDL, LDL and VLDL. There is statistically highly significant decrease in BMI, Waist-hip ratio, total cholesterol, triglycerides, LDL- C, VLDL- C, and highly significant increase in HDL- C in physically trained adults as compared to sedentary adults. From the results, it is concluded that combination of aerobic exercise and games causes highly significant decrease in total cholesterol, TG, LDL- C, VLDL-C and increase in HDL-C. Thus, combination of aerobic exercise and games is more beneficial instead of only aerobic exercise and hence should be recommended.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"47 1","pages":"5465-5469"},"PeriodicalIF":0.0,"publicationDate":"2017-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80023148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the growth and sporulation of different entomopathogenic fungi in different liquid and solid media at varied concentrations","authors":"K. Teja, S. J. Rahman","doi":"10.21746/ijbio.2017.08.003","DOIUrl":"https://doi.org/10.21746/ijbio.2017.08.003","url":null,"abstract":"Entomopathogenic fungi like Beauveria bassiana, Metarhizium anisopliae and Lecanicillium lecanii are used in biological control of agricultural insect pests. Their specific mode of action makes them an effective alternative to the chemical Insecticides. Virulent strains of Entomopathogenic fungi are effectively formulated and used as bio-insecticides world-wide. Amenable and economical multiplication of a virulent strain in a large scale is important for them to be useful in the field. Culture media plays a major role in the large-scale multiplication of virulent strains of Entomopathogens. Different substrates and media components are being used for this purpose. Yet, each strain differs in its nutritional requirements for the maximum growth and hence it is necessary to standardize the right components and their optimum concentrations in the culture media for a given strain of Entomopathogen. In the current study, three different nitrogen sources and two different carbon sources were tried to standardize the mass multiplication media for seven test isolates of Entomopathogenic fungi. A study was also conducted to determine the ideal grain media for the optimum conidial yields of the test isolates. Yeast extract was found to be the best Nitrogen source for the isolates. The isolates tested, differed in their nutritional requirements and showed variation in the best nitrogen and carbon sources necessary for their growth. Variation was also found in the optimum concentration of both the ingredients for the growth and sporulation of the isolates. In the solid-state fermentation study, rice was found to be the best grain for the growth of most of the fungi followed by barley. The significance of such a study in the development of an effective Myco-insecticide is vital and can be successfully employed in agriculture is discussed.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"1 1","pages":"5459-5464"},"PeriodicalIF":0.0,"publicationDate":"2017-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88931987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GnRH-1, GnIH mRNA and Luteinizing Hormone in Domestic hens (Gallus gallus domesticus) Exposed to Different Wavelengths of light","authors":"I. J. Reddy, A. Mishra, S. Mondal","doi":"10.21746/IJBIO.2017.08.001","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.08.001","url":null,"abstract":"The objective of this study was to establish the effects of red spectrum of light (650nm, treated n=12) and normal spectrum of light (450nm control=12) on GnRH-I and GnIH mRNA expression, amplitude and frequency of luteinizing hormone (LH) and egg production from 42 to 52 weeks of age in white leghorn hens . Blood samples were collected at weekly interval from both the groups. At the 47th week of age blood samples from both the groups were collected at every 3 h for 36h to study the pulsatile secretion of LH surges. GnRH and GnIH mRNA expression pattern was studied between control and treated birds. Egg production and pause days were calculated between the two groups. LH concentration in the plasma was increased significantly (P<0.01) in hens exposed to red spectrum of light. Plasma LH concentration was higher (P<0.01) in treated birds with more number of LH surges. The amplitude and frequencies of LH were advanced in birds exposed to red spectrum of light during 36 h of sampling at 3h intervals. GnRH-I mRNA concentration was significantly (P<0.01) higher, whereas GnIH mRNA was significantly (P<0.01) lower in birds exposed to red spectrum of light compared to controls. It is hypothesized that exposure of birds to red spectrum of light enhanced (P<0.01) GnRH-I mRNA, along with LH required for ovulation and egg lay. During 77 days (42-52 weeks of age) of the experimental period, egg production was increased (p<0.01) with lower incidence of pause days in the treated group. It is concluded that low GnIH mRNA and higher levels of GnRH-I mRNA, LH, lower number of pause days enabled the birds to lay more eggs by stimulating GnRH through red spectrum of light.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"2010 1","pages":"5446-5451"},"PeriodicalIF":0.0,"publicationDate":"2017-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86274402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Abdel-Reheim, B. Mahmoud, H. Soliman, B. Ismail
{"title":"Treatment of rotenone induced neurodegeneration by taurine and hesperidin","authors":"E. Abdel-Reheim, B. Mahmoud, H. Soliman, B. Ismail","doi":"10.21746/IJBIO.2017.08.002","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.08.002","url":null,"abstract":"Taurine (2-aminoethane sulphonic acid) is a sulphonic acid which is derived from cysteine and is widely distributed in animal tissues. It is one of the most abundant amino acid in mammals and plays several crucial roles including modulation of calcium signaling, osmoregulation and membrane stabilization. Hesperidin occurs in the cells in crystalline, feather-like aggregates or sphaerocrytalline masses and it exhibits pharmacological and biological properties such as anti-inflammatory, anticarcinogenic, inhibit bone loss, lowering of lipid, hypoglycaemic and antioxidant activities. The current study was performed to evaluate the effect of taurine and hesperidin on neurodegeneration resulted from rotenone administration by a dose of 1.5 mg/kg b.wt three times per week for two months. Also we summarize recent findings emphasizing the role of catecholamines neurotransmitters, Tyrosine hydroxylase and oxidative stress in neurodegenerative disease model. These rats received taurine and hesperidin through gastric intubation daily for one month after rotenone administration. The results revealed that taurine and hesperidin treatment significantly ameliorated the decreased levels of the catecholamines neurotransmitters and Tyrosine hydroxylase which were decreased as after rotenone injection. Moreover, taurine and hesperidin treatment ameliorated lipid peroxidation and catalase levels.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"54 1","pages":"5452-5458"},"PeriodicalIF":0.0,"publicationDate":"2017-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80189338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An overview of Osmotic Drug Delivery System: An update review","authors":"Hiren Patel, Vaishnavi Parikh","doi":"10.21746/IJBIO.2017.07.001","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.07.001","url":null,"abstract":"The pharmaceutical industry has faced several marked challenges in order to bring new chemical entities (NCEs) into the market over the past few decades. Various novel drug delivery approaches have been used as a part of life cycle management from which Osmotic drug delivery systems look the most promising one. After discussing the history of osmotic pump development, this article looks at the principles, advantages and disadvantages of osmotic drug delivery systems. Then, the basic components of osmotic pump and factors affecting the design of oral osmotic drug delivery systems are discussed in detail. In the later part of the manuscript, various types of osmotic pumps available in the market and evaluation methods for osmotic drug delivery systems are discussed in detail.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"85 1","pages":"5426-5436"},"PeriodicalIF":0.0,"publicationDate":"2017-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73204355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of imidacloprid treatment on Protein Profiling of soil isolate Bacillus weihenstephanensis","authors":"A. Shetti, B. Kaliwal","doi":"10.21746/IJBIO.2017.07.002","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.07.002","url":null,"abstract":"Imidacloprid has gained great attention as a synthetic insecticide that acts in a similar manner as nicotine and is now widely used for the control of pests. Bacteria react to environmental or chemical stress by synthesizing specific sets of proteins and these can be analyzed by protein profiling using SDS PAGE. The present investigation was undertaken to reveal protein profile changes and differentially expressed proteins in soil isolate Bacillus weihenstephanensis on dose and durational exposure to imidacloprid. Protein profiling of Bacillus weihenstephanensis treated with different (10 -7 to 10 -3 M) concentrations of imidacloprid observed regularly at the duration of 24 hrs for a period of 96 hours, showed the over expressions of certain protein, expression of stress proteins and novel proteins. The proteins expressed were observed to be dose and durational dependent. The present investigation proves that imidacloprid exposure induces the expression of stress and novel proteins in soil isolate Bacillus weihenstephanensis . The expression of these proteins may be necessary for the protection of the Bacillus weihenstephanensis from toxic effects of imidacloprid. The specific protein profiles that are expressed in response to the stress induced by imidacloprid can be used to monitor the environmental samples for the presence of similar pollutants.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"5 1","pages":"5437-5440"},"PeriodicalIF":0.0,"publicationDate":"2017-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90069428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Green synthesis of silver nanoparticles from Psidium guajava leaves and its antibacterial activity","authors":"G. Venugopal","doi":"10.21746/IJBIO.2017.07.003","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.07.003","url":null,"abstract":"In the present study, Psidium guajava leaves were taken for synthesizing silver nanoparticles and checked their antibacterial activity against E.coli, Klebsiella, Pseudomonas, Staphylococcus and Acinetobacter . The plant extract was analysed for the detection of the presence of protein, carbohydrate, flavonoids, terpenoids, glycosides, steroids, saponins, phenols and tannins. In this present study, the antibacterial activity of green synthesized silver nanoparticles from guava leaf shows the zone of inhibition against all the five pathogens.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"73 1","pages":"5441-5443"},"PeriodicalIF":0.0,"publicationDate":"2017-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73892073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Raorane, D. Desai, G. Kukreja, S. Desai, C. Nadkarni
{"title":"Genome sequence announcement of potential phthalic acid degrader Pseudomonas aeruginosa HNYM 41 and Bacillus cereus BVC 11 isolated from plastic dumping ground area","authors":"C. Raorane, D. Desai, G. Kukreja, S. Desai, C. Nadkarni","doi":"10.21746/IJBIO.2017.07.004","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.07.004","url":null,"abstract":"Putative phthalic acid degrader Pseudomonas aeruginosa HNYM 41 and Bacillus cereus BVC 11 isolated from plastic dumping ground area of Ahmednagar city. Here we report the genome sequence of HNYM 41 and BVC 11, which have capacity to degradation capacity up to 1500 and 3000 ppm in absent of other carbon source.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"20 1","pages":"5444-5445"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81190189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seasonal variations in the biochemical composition of muscle and liver of marine fishes, Gazza achlamys and Ariomma indica from Visakhapatnam coast, South India.","authors":"K. S. Prasad, N. Prasad, Venkateswarlu Ch.","doi":"10.21746/IJBIO.2017.06.005","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.06.005","url":null,"abstract":"Seasonal variations in biochemical constituents were observed in muscle and liver of two marine fishes i.e. Gazza achlamys and A riomma indica . The result indicated that muscle proteins are low in monsoon season in A. indica and in all seasons in G. achlamys. When compared to muscle, carbohydrate and lipids levels are very high in liver tissue of A . indica . Whereas there is a slight difference in G. achlamys . It is well understood from the current study that each habitat group of fishes has its own nutritional value parameters with sense to their different food preferences. This shows the mobilization of biochemical constituents in body tissues during different seasons. Based on current finding, it is concluded that G. achlamys and A. indica are the good source of protein, carbohydrates and lipids.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"59 1","pages":"5407-5414"},"PeriodicalIF":0.0,"publicationDate":"2017-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73824713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ravikanth Vysyaraju, B. H. Rao, I. V. S. Rao, J. Venkateswarlu, Prasad K.V.V., V. Siddaiah
{"title":"A novel process for the preparation of [(R,S)/ (S,R)] and [(S,S)/ (R,R)] chroman epoxides, key intermediates in the synthesis of Nebivolol","authors":"Ravikanth Vysyaraju, B. H. Rao, I. V. S. Rao, J. Venkateswarlu, Prasad K.V.V., V. Siddaiah","doi":"10.21746/IJBIO.2017.06.007","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.06.007","url":null,"abstract":"A novel, cost effective, scalable process for the preparation of chroman epoxides starting from 4-fluorophenol is described. The highlights of the process are single step O -acylation, fries rearrangement, one pot synthesis of claisen condensation, cyclization, reduction, epoxidation with over all yield of 50.9% [( R , S )/( S , R )]-chroman epoxide-A is 33.9% and [( S , S )/( R , R )]-chroman epoxide-B is 17%.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"53 1","pages":"5420-5425"},"PeriodicalIF":0.0,"publicationDate":"2017-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83409403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}