{"title":"Monthly variation and impact of pollution on the nutritional value of Moringa oleifera (Lam.) Leaves","authors":"Sachin Dubey, M. Kapoor","doi":"10.21746/IJBIO.2017.6.10.5","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.6.10.5","url":null,"abstract":"Moringa oleifera Lam. , commonly found tree in sub-Himalayan tracts of India, Pakistan, Bangladesh and Afghanistan has a high nutrition value. The leaves, flowers and immature pods of Moringa are used as a vegetable in many countries. The leaves are highly nutritious and medicinal in nature. They are a rich source of iron, calcium, vitamin A, vitamin C, proteins, and essential amino acids. Hence Moringa leaves can be a good source of protein for the vegetarians and the under-nourished population. Present investigation deals with the study of monthly variation in the nutritional value of Moringa leaves from the month of June 2015 to January 2016. Impact of urban sewage pollution and roadside vehicular pollution on the amount of reducing and total sugars, chlorophylls (a, b and total), proteins, vitamin-C and pH of the leaves, was also studied. Results revealed that the highest amounts of reducing sugars, total sugars, chlorophyll b and total chlorophyll during October 2015 whereas proteins, chlorophyll a , vitamin C and pH were highest during January 2016. Leaf samples collected from all the study sites exhibited minimum amounts of reducing sugars, chlorophylls (a, b and total) and pH during July 2015 whereas total sugars were lowest during December 2015. Proteins and vitamin C values were lowest during August and June 2015 respectively. Sewage and vehicular pollution showed an adverse effect on the nutritional contents of Moringa oleifera leaves. Of the two polluted sites, samples from near the sewage flow showed higher impact.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"53 1","pages":"5535-5542"},"PeriodicalIF":0.0,"publicationDate":"2017-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81536200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Narang, Jeevan Singh Tityal, Amit Jain, Reena Kulshreshtra, F. Khan
{"title":"Nanobiotics: Challenging the anti-microbial perspective - The game changer?","authors":"D. Narang, Jeevan Singh Tityal, Amit Jain, Reena Kulshreshtra, F. Khan","doi":"10.21746/IJBIO.2017.6.10.2","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.6.10.2","url":null,"abstract":"Antibiotics are the most important medical inventions in human history and are the invaluable weapons to fight against various infectious diseases. Multi drug resistant microorganisms are becoming a serious issue and increasingly public health problem in present day scenario. Antibiotics are becoming less useful due to increasing bacterial resistance. Development of new and more powerful antibiotics leading to drastic pathogens response by developing resistance to the point where the most powerful drugs in our arsenal are no longer effective against them. New strategies for the management of bacterial diseases are urgently needed and nanomaterials can be a very promising approach. Nanobiotics uses nano-sized tools for the successful management bacterial diseases and to gain increased understanding of the complex underlying patho-physiology of disease. (European Science Foundation. Forward Look Nanomedicine: An EMRC Consensus Opinion 2005. Available online: http://www.esf.org (accessed on 15 July 2017). The application of nanotechnologies to medicine, or nanomedicine, which has already demonstrated its tremendous impact on the pharmaceutical and biotechnology industries, is rapidly becoming a major driving force behind ongoing changes in the antimicrobial field. Present review providing important insights on nanobiotics, and their preparation, mechanism of action, as well as perspectives on the opportunities and challenges in nanobiotics.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"30 1","pages":"5518-5524"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84190304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seasonal variation of proximate composition of Istiophorus platypterus from Visakhapatnam fishing harbor, East Coast of India.","authors":"P. Kiran, Y. Annapurna, P. Krishna, K. Sreeramulu","doi":"10.21746/IJBIO.2017.6.10.4","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.6.10.4","url":null,"abstract":"Seasonal variation of proximate composition (moisture, protein, fat and ash) of Istiophorus platypterus was analysed for one year (January 2016 to December 2016) from Visakhapatnam fishing harbor, east coast of India. The results indicated that the proximate composition of the fish depends on season. The total mean values of moisture percentage was found more in monsoon (78.36±0.09) season, followed by pre-monsoon (77.90±0.12) and post-monsoon (77.81±0.17), whereas protein content was found more in pre-monsoon (18.38±0.09) season followed by monsoon (17.45±0.09) and post-monsoon (16.52±0.09) season, the fat percentage was accumulated more in the season of post-monsoon (2.15±0.07) followed by pre-monsoon (2.13±0.12) and monsoon (1.81±0.10), while ash content observed high in post-monsoon (3.15±0.16) followed by monsoon (1.97±0.08) and pre-monsoon (1.46±0.150 season respectively.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"35 1","pages":"5530-5534"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87429307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study on prevalence of contraception and estimate unmet need of family planning among married women in the rural Shamirpet, Ranga Reddy District, T.S, India.","authors":"L. Vijayasree","doi":"10.21746/IJBIO.2017.6.10.1","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.6.10.1","url":null,"abstract":"The study on contraceptive use and unmet need for family planning is the key to understanding the change in fertility and improving reproductive health. Family planning program aims to not only achieve population stabilization but also to promote reproductive health and reduce maternal, infant & child mortality and morbidity. In this study an attempt has been made to assess the family planning practices adopted in the rural Shamirpet. Probability proportion sampling was done and 402 women were selected from 13 villages. Prevalence of contraception was found to be 61.7%. Permanent methods were preferred over temporary methods. Total unmet need for family planning was 11.7%. The contraceptive prevalence rate found in the present study is higher than the district figures and is on par with the state statistics. Unmet needs also are low compared to state figures.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"78 1","pages":"5513-5517"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79687857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A review on cost effective analysis of antiepileptic drugs","authors":"S. S. Uthara, M. Basheer, A. Babu","doi":"10.21746/IJBIO.2017.9.6","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.9.6","url":null,"abstract":"80% of the epilepsy patients were resides in developing countries. 12 million patients with epilepsy were in India that is One-sixth of the global burden is due to epilepsy. Those diseases were treated properly there is a greater reduction in seizure and people may leads to proper life, if untreated that may become a large increase in burden. Drugs are the main treatment for epilepsy. As compared with conventional AEDs newer drugs are much expensive some newer drugs were 10 to 20 times costlier than older drugs. if those expensive drugs reduce the seizure events, improves the quality of life and with lesser ADRs then the benefit justify the higher cost of the drug. The epilepsy burden can be reduced mainly by giving epilepsy care at low cost, given the lack of expertise in the management of epilepsy in poor areas.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"19 1","pages":"5507-5512"},"PeriodicalIF":0.0,"publicationDate":"2017-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75206597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of BMI and waist-hip ratio in physically trained adults and sedentary adults","authors":"S. Pawar","doi":"10.21746/ijbio.2017.9.3","DOIUrl":"https://doi.org/10.21746/ijbio.2017.9.3","url":null,"abstract":"Obesity can increase the incidence of angina pectoris, myocardial infarction, hypertension and cerebrovascular diseases. This study is undertaken with the aim to evaluate the effect of physical training on BMI, Waist-hip ratio. The study was conducted on 50 male physically trained adults and 50 male sedentary adults in the age group between 30-40 years and the following parameters were evaluated BMI, Waist-hip ratio. There is statistically highly significant decrease in BMI, Waist-hip ratio, in physically trained adults as compared to sedentary adults. Aerobic exercise and games in combination causes highly significant decrease in BMI, W-H ratio. Thus, combination of aerobic exercise and games is more beneficial instead of only aerobic exercise and hence should be recommended.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"26 1","pages":"5485-5488"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85528392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A critical review on integrating multiple fish biomarkers as indicator of heavy metals contamination in aquatic ecosystem","authors":"Vijay Hemmadi","doi":"10.21746/ijbio.2017.9.5","DOIUrl":"https://doi.org/10.21746/ijbio.2017.9.5","url":null,"abstract":"An immense amount of data is available on biomarkers related to different eco-toxicants. But data on contaminant-specific biomarkers in fishes is sparse. Traditionally, detection and quantification of heavy metals in sediment, water, and biota gave us valuable information on the quantity and the type of heavy metal present in the ecosystem. This information can be utilized to select a heavy metal specific biomarker. For an instance, if Cadmium (Cd), Zinc (Zn) and Cupper (Cu) are at high concentration, then Metallothionein (MT) can be a good candidate biomarker. Along with this, Superoxide dismutase (SOD) is a very potent indicator of Iron (Fe) and Mercury (Hg) contamination and also Catalase (CAT) is specific for Cadmium (Cd) and Zinc (Zn) exposure. For these kinds of selection of biomarker, the researchers should know heavy metals type specific biomarker. This review is the small effort towards cumulating the heavy metals type specific biomarker. This demonstrates the exposure and effects of heavy metals in fishes by integrating the heavy metal quantification and biomarker selection.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"27 1","pages":"5494-5506"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83065630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vikas Kumar, Krishna Kumar, P. Kumari, Raj Kumar, S. Saxena, O. Chaurasia
{"title":"Effect of plant growth regulators on germination of seed of Podophyllum hexandrum in high altitude region of Ladakh, India.","authors":"Vikas Kumar, Krishna Kumar, P. Kumari, Raj Kumar, S. Saxena, O. Chaurasia","doi":"10.21746/IJBIO.2017.9.1","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.9.1","url":null,"abstract":"This study shows an effective but simple method of conserving characterised populations through seed germination modification and treatment with plant growth regulators. It is tolerant to cold temperature, as would be expected of a Northern Himalayan plant, but not tolerant to dry conditions. Podophyllum hexandrum seed dormancy has been considered to be a major constraint and most of the earlier reports recommended dormancy breaking pre-treatments such as chilling, gibberellic acid (GA 3 ). However, in this study, we showed that the pre-treatment of seeds with IAA, IBA and GA 3 plant growth regulators at high altitude (Leh - Ladakh) to analyse the effects on germination percentage of seeds and morphological characteristics of the treated seeds over control seeds. The pre-treatment helps the seeds to give high germination percentage than control seedlings. The treated seedling showed a high degree of growth especially the seedlings treated with GA 3 . These seedlings in the greenhouse showed very prominent growth in height and leaf as compared to the control seedling plants.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"34 1","pages":"5470-5473"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90832380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The protective effect of Nigella Sativa oil extract against neurotoxicity induced by Valproic acid","authors":"B. Morsy, G. Safwat, D. Hussein, R. M. Samy","doi":"10.21746/IJBIO.2017.9.2","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.9.2","url":null,"abstract":"Nigella sativa (NS), commonly known as black cumin, has been used for medicinal purposes. Traditionally the seeds and its oil are used in several diseases. The greatest part of the remedial properties of this plant is due to the presence of thymoquinone (TQ) which is a major active chemical component of the essential oil . The current study performed to evaluate the effect of Nigella sativa Oil (NSO) extract on the neurotoxic and hepatotoxic potentials from Valproic acid (VPA) administration . Also we summarize recent findings emphasizing the role of main neurotoxic and hepatotoxic markers and oxidative stress in study’s case. Neurotoxicity was induced by VPA at dose of (500 mg/kg b.wt) by gastric intubation daily for 30 day. These rats received NSO extract was given orally at dose of (0.5 ml/kg b.wt) daily for 30 days after VPA administration. The current results revealed that NSO extract treatment ameliorated significantly the elevated levels of the neurotoxic and hepatotoxic biomarkers which elevated as a result to VPA administration. Moreover, NSO extract treatment ameliorated the non-enzymatic antioxidant, brain and liver lipid peroxidation (LPO) and glutathione (GSH) concentration and the enzymatic antioxidant, brain and liver catalase(CAT) activity.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"218 1","pages":"5474-5484"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75614065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Abdel-Moneim, W. El-Senousy, M. Abdel-Latif, Rehab G Khalil, A. Arafa
{"title":"Increased incidence of Anti - IgG of Coxsackievirus and Cytomegalovirus among diabetic children in Egypt.","authors":"A. Abdel-Moneim, W. El-Senousy, M. Abdel-Latif, Rehab G Khalil, A. Arafa","doi":"10.21746/IJBIO.2017.9.4","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.9.4","url":null,"abstract":"Cytomegalovirus (CMV) and Coxsackievirus (CV) are included in the environmental factors potentially relevant to the pathogenesis of type 1 diabetes (T1D). Thus, this study aimed to detect the prevalence of both anti-IgG for each of CV and CMV in diabetic children with (EV + ) or without (EV - ) enteroviruses infection. The current study revealed that the T1D-EV + and T1D-EV - groups had marked elevations in hemoglobin A1c (HbA1c), C-reactive protein (CRP) and glutamic acid decarboxylase autoantibodies (GADA) as compared to non-diabetic control. Moreover, anti-IgG for the CV and CMV groups were detected in three groups; diabetic infected (T1D-EV + ), diabetic non-infected (T1D-EV - ) and control group. Detection of anti-CV IgG achieved 22.7%, 6.7% and 64% in control, T1D-EV - and T1D-EV + , respectively. However, detection of anti-CMV IgG revealed 23.4%, 50% and 40% in control, T1D-EV - and T1D-EV + , respectively. In conclusion, the prevalence of the antibodies of CV-IgG and CMV-IgG in the sera of diabetic children more than that in healthy control children may give a role of these viruses in the etiology and progression of T1D.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"54 1","pages":"5489-5493"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90756360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}