International Archives of Occupational and Environmental Health最新文献

{"title":"Occupational air pollutant exposure and seasonal variation in respiratory outcomes among brick kiln workers.","authors":"Sohaib Hasnain, Nadia Akram, Asim Mansha, Toheed Asghar, Khalid Mahmood Zia","doi":"10.1007/s00420-026-02208-4","DOIUrl":"10.1007/s00420-026-02208-4","url":null,"abstract":"<p><p>OBJECTIVE: This study aimed to determine whether workers in fixed chimney Bull’s trench kilns (FCBTK) experience greater occupational exposure to air pollutants and more pronounced respiratory impairment than those in zigzag kilns, and to evaluate how seasonal production variations affect the relationship between exposure and respiratory outcomes. We hypothesized that FCBTK workers would demonstrate higher pollutant exposure and greater respiratory dysfunction, with seasonal peaks exacerbating these differences. METHODS: A cross-sectional comparative study was conducted in Jaranwala, district Faisalabad, between April to August (Low) and November to January (High) in 2022–2023, among 160 male workers from 20 kilns (10 FCBTK, 10 zigzag). Ambient PM2.5, PM10, CO, and SO2 were measured at kiln worksites using calibrated portable monitors. Spirometry was performed according to ATS/ERS guidelines and expressed as % predicted (GLI 2012). Seasonal pollutant levels were assessed where available. Associations between pollutants and lung function were evaluated using correlation and multivariable logistic regression models adjusted for age, smoking, BMI, and employment duration. RESULTS: Ambient CO, SO2, PM2.5, and PM10 levels were significantly higher at FCBTK sites than zigzag kilns (e.g., CO: 12.8 ± 2.9 vs. 8.4 ± 2.2 ppm; mean difference 4.4 ppm, 95% CI 3.6–5.2; p < 0.001). Seasonal data showed sharp increases in pollutant concentrations during peak kiln activity months, with FCBTK sites reaching mean PM2.5 levels of 168 µg/m3 vs. 94 µg/m3 in zigzag kilns, PM10 levels of 280 µg/m3 vs. 160 µg/m3, CO levels of 15.4 ppm vs. 9.6 ppm, and SO2 levels of 92 ppb vs. 58 ppb. These seasonal peaks were accompanied by more pronounced declines in lung function, with mean FEV1% predicted dropping by 9.4% and FVC by 7.8% among FCBTK workers compared to 4.1% and 3.5% declines, respectively, in zigzag kiln workers. Overall, FCBTK workers had lower mean FEV1% predicted (82.6 ± 9.4 vs. 88.7 ± 8.1; difference − 6.1, 95% CI − 8.8 to − 3.4; p < 0.001) and higher prevalence of abnormal spirometry (22.5% vs. 10.0%; difference 12.5%, 95% CI 2.1–22.9; p = 0.03). CO exposure independently increased the odds of abnormal spirometry by 42% per ppm (adjusted OR 1.42, 95% CI 1.16–1.74). CONCLUSION: FCBTK workers face substantially higher pollutant exposure and more pronounced respiratory impairment than zigzag kiln workers, with seasonal peaks marked by extreme elevations in PM2.5, PM10, CO, and SO2, which further exacerbate the risk of lung function decline. Transition to cleaner kiln technologies, coupled with occupational health surveillance and targeted seasonal interventions, could markedly improve respiratory outcomes in this workforce.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dialkylphosphate urinary metabolites and cholinesterase activities in Mexican indigenous farmworkers.","authors":"Diana M Paredes-Céspedes, José F Herrera-Moreno, Aurora E Rojas-García, Irma M Medina-Díaz, Briscia S Barrón-Vivanco, Cyndia A González-Arias, Francisco A Verdín-Betancourt, Néstor Ponce-Ruíz, Yael Y Bernal-Hernández","doi":"10.1007/s00420-026-02206-6","DOIUrl":"10.1007/s00420-026-02206-6","url":null,"abstract":"<p><strong>Purpose: </strong>Organophosphate (OP) pesticides are widely used in agriculture, vector control, and represent a global public health concern, particularly for occupationally exposed farmers and applicators. This study aimed to evaluate the associations among urinary dialkylphosphate (DAP) metabolites, cholinesterase activities, and butyrylcholinesterase (BuChE) polymorphisms in an indigenous population in Mexico.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 191 farmworkers. Data were collected using a structured questionnaire addressing sociodemographic characteristics, lifestyle factors, pesticide exposure, and dietary intake. Venous blood and urine samples were obtained to determine cholinesterase activities and urinary DAP concentrations, respectively.</p><p><strong>Results: </strong>Detectable urinary DAP levels were identified, with dimethylthiophosphate (DMTP) as the predominant metabolite. BuChE activity was significantly associated with dietary lipid and carbohydrate intake. A high prevalence of ancestral genotypes was observed in the BuChE gene. Age-stratified analyses demonstrated differences in cholinesterase activities, and males with low BuChE activity exhibited higher urinary DAP metabolite concentrations.</p><p><strong>Conclusion: </strong>These findings highlight variability in OP pesticide metabolite levels and their relationships with dietary factors and genetic background among indigenous agricultural workers. Improved understanding of these interactions is essential for mitigating exposure-related health risks in vulnerable populations.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between psychosocial working conditions and sickness absence days among employees reporting symptoms of common mental disorders in Germany.","authors":"Meike Heming, Florian Angerer, Christoph Kröger, Gianni Lidolt, Nicole R Hander, Eva Rothermund, Harald Gündel, Nadine Mulfinger, Ute Schröder, Uta Wegewitz, Regina Herold, Peter Angerer","doi":"10.1007/s00420-026-02205-7","DOIUrl":"10.1007/s00420-026-02205-7","url":null,"abstract":"<p><p>PURPOSE: Psychosocial working conditions influence the risk for sickness absence days. These relationships can differ for employees with common mental disorders (CMDs). This study therefore investigates relationships between psychosocial working conditions and sickness absence days in employees reporting CMD symptoms. METHODS: Data of participants of a randomized controlled trial are investigated (n = 529). The Copenhagen Psychosocial Questionnaire assessed 12 scales of working conditions at baseline. The outcomes number of sickness absence days were assessed nine and 15 months later, as well as during the follow-up period. Negative binomial regression analyses were adjusted for several factors and were conducted for imputed data and supplemented by complete case analyses. RESULTS: Influence at work was associated with lower risks of sickness absence days nine (RR= -0.009, CI= − 0.018; − 0.001) and 15 months later (RR= − 0.008, CI= − 0.015; 0.000). Dissolution (i.e., reporting to work outside of work hours or being available for colleagues during free time) was associated with lower risks of sickness absence days during the follow-up period. Complete case analyses showed positive associations between social support and sickness absence days nine (RR = 0.01, CI = 0.0; 0.02; n = 377) and 15 months later (RR = 0.01, CI = 0.0; 0.03; n = 320). CONCLUSIONS: Among employees reporting symptoms of CMDs, influence at work and dissolution predicted sickness absence days for different time periods. However, many psychosocial working conditions showed no such relevance, indicating that other factors may be more relevant in regard of sickness absence days among this particular group of employees. TRIAL REGISTRATION: The randomized controlled trial was registered at the German Clinical Trial Register on 01.03.2021 (DRKS00023049; https://drks.de/search/en/trial/DRKS00023049).</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12979410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147432681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DNA methylation as an epigenetic marker of children's exposure to traffic-related air pollution in the Klang Valley, Malaysia.","authors":"Juliana Jalaludin, Nur Faseeha Suhaimi, Suhaili Abubakar","doi":"10.1007/s00420-026-02204-8","DOIUrl":"10.1007/s00420-026-02204-8","url":null,"abstract":"<p><p>PURPOSE: Traffic-related air pollution (TRAP) poses significant health risks to children. While adverse outcomes have been reported, the biological mechanisms underlying these effects remain unclear. This study investigates the association between TRAP exposure and DNA methylation (DNAm) changes in TNFα and CYP1A1 genes as potential epigenetic markers among school children in Malaysia. METHODS: A cross-sectional comparative study was conducted involving 248 children aged 7–11 years from high-traffic (HT) and low-traffic (LT) areas in the Klang Valley. Environmental monitoring was performed at both schools and residences to measure levels of PM10, PM2.5, PM1, NO2, SO2, O3, CO, total volatile organic compounds (TVOC), and black carbon (BC). Dietary intake and other potential confounders were assessed via validated questionnaires. Saliva samples were collected and analyzed for DNAm status using methylation-specific polymerase chain reaction (MS-PCR) targeting TNFα and CYP1A1 genes. RESULTS: Pollutant levels were significantly elevated in HT schools (p < 0.001), whereas LT schools recorded higher CO2 concentrations. Children in HT areas had significantly higher methylation in TNFα (54.0% vs. 37.1%; OR = 2.0, p = 0.007) and CYP1A1 (51.6% vs. 37.9%; OR = 1.7, p = 0.030). TNFα methylation was associated with NO2 exposure (OR = 3.0, 95% CI 0.88–1.95, p = 0.036), while CYP1A1 methylation was linked to BC exposure (OR = 2.0, 95% CI 1.02–2.03, p = 0.019). No significant association was observed for residential TRAP exposure. CONCLUSION: TRAP exposure in school environments is associated with gene-specific epigenetic modifications in children, suggesting potential utility of DNAm as an early biomarker and reinforcing the need for targeted mitigation strategies.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal occupational physical activity during pregnancy and childhood cancers in Denmark 1968-2013.","authors":"Xiwen Huang, Garikayi Chemhaka, Johnni Hansen, Chuanjie Deng, Niklas Krause, Beate Ritz, Julia E Heck","doi":"10.1007/s00420-026-02203-9","DOIUrl":"10.1007/s00420-026-02203-9","url":null,"abstract":"<p><p>OBJECTIVE: To examine associations between maternal occupational physical activity (OPA) during pregnancy and childhood cancer risk in offspring. METHODS: The study population included all cancer cases born in Denmark between 1968 and 2013, aged 0–19 at diagnosis between 1968 and 2016 (N = 7077). Sex- and birth-year matched controls (ratio 1:25) were randomly selected from the Central population registry. maternal OPA was assessed by a job exposure matrix based on the nordic occupational cancer study (score: heavy or rather heavy physical work versus all other levels). Unconditional logistic regression adjusted for potential confounders was used to estimate effects. Dose-response relationships examined by OPA exposure probability groups (high, medium, low versus no exposure). RESULTS: Medium cumulative maternal OPA exposure was associated with an average 8% increased childhood cancer risk for all cancers combined. Medium and high intensity OPA during pregnancy were positively associated with medulloblastoma (adjusted odds ratio (OR) = 1.53, 95% confidence interval (CI) 1.01–2.31 and OR = 2.01, 95% CI 1.20–3.37, respectively). Various measures of OPA were most consistently associated with increased risks of medulloblastoma. Among healthcare professionals, high OPA also increased melanoma risk in offspring (OR = 1.48, 95% CI 1.00-2.19). CONCLUSIONS: Higher levels of maternal OPA are associated with increased risks of medulloblastoma, and possibly melanoma in the offspring. If associations are corroborated, regulations should be considered to protect women of child-bearing age from being exposed to high levels of physical activity at work.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Favorable changes in health- and work-related factors and subsequent work ability in midlife and older social and health care employees.","authors":"Joonas Poutanen, Mikko Härmä, Tea Lallukka, Matti Joensuu, Eija Haukka, Aki Koskinen, Jenni Ervasti, Rahman Shiri","doi":"10.1007/s00420-025-02200-4","DOIUrl":"10.1007/s00420-025-02200-4","url":null,"abstract":"<p><p>OBJECTIVE: This quasi-experimental study aimed to examine whether favorable changes in health- and work-related factors improve work ability of midlife and older workers. METHODS: The study included 2,312 Finnish social and health care employees (89.4% women, mean age 51.5 ± 5.8 years) who participated in repeated surveys between 2017 and 2022. Propensity score weighting and generalized linear models were applied to estimate the associations of a one standard deviation favorable change in health and lifestyle factors, psychosocial work environment and working hour characteristics with perceived work ability. RESULTS: Favorable changes in health-related factors including improvement in sleep quality (RR 2.03, 95% CI 1.47–2.82), reduction in psychological distress (RR 1.68, 95% CI 1.24–2.30), increase in leisure-time physical activity (1.53, 95% CI 1.13–2.08), quitting smoking (RR 1.58, 95% CI 1.01–2.48), decrease in alcohol intake (RR 2.21, 95% CI 1.54–3.17) were associated with improved work ability. Of work-related factors, reduction in job demands (RR 1.51, 95% CI 1.12–2.03) and job demand-control ratio (RR 1.55, 95% CI 1.11–2.16), and increase in job control (RR 1.49, 95% CI 1.05–2.13) and job rewards (RR 1.60, 95% CI 1.20–2.13) were associated with improved work ability. CONCLUSIONS: Positive changes in modifiable health- and work-related risk factors can improve work ability of midlife and older social and health care employees. These identified risk factors are essential in design and implementation of multidimensional interventions aimed at supporting extended workforce participation among older workers.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 2","pages":"14"},"PeriodicalIF":2.7,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12894155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the relationship between noise exposure and arterial blood pressure and lipid profile disorders in wood industry workers: a cross-sectional study.","authors":"Majid Fallahi, Zahra Goleyj Mofrad, Akbar Ahmadi Asour","doi":"10.1007/s00420-025-02199-8","DOIUrl":"10.1007/s00420-025-02199-8","url":null,"abstract":"<p><p>OBJECTIVE: Exposure to noise elevates stress hormones and alters metabolism, raising cholesterol and triglyceride levels, thereby increasing cardiovascular risk. This study investigates the link between occupational noise, blood pressure, and lipid profiles in wood industry workers. METHODS: This cross-sectional study involved 249 male employees with at least one year of full-time employment in the wood industry. Participants were categorized into two groups: 166 workers exposed to noise levels exceeding 85 decibels (dB) (case) and 83 workers exposed to lower noise levels (control). Personal data, blood pressure measurements, and lipid profiles were obtained from existing medical records, and ambient noise levels were measured using a TES 1358C sound level meter. RESULTS: The findings indicated that workers in the case group, had significantly higher levels of TGC and LDL compared to those in the control group.The mean triglyceride levels were 330.55 mg/dL in the case group and 275.40 mg/dL in the control group, and mean LDL levels were 194.87 mg/dL and 155.42 mg/dL, respectively. Both TGC and LDL levels in both groups were notably higher than the standard clinical ranges. In the case group, positive significant correlations were observed between TGC and LDL, TGC and SBP, and LDL and SBP. The multiple linear regression analysis indicated that noise (β = 0.421, p = 0.014), age (β = 0.349, p = 0.001), work experience (β = 0.384, p = 0.004), and BMI (β = 0.230, p = 0.032) as a independent variables accounted for 27.5% of the variability in TGC in the case group. CONCLUSION: This study indicates a heightened risk of metabolic and cardiovascular disorders within this population. Therefore, implementing effective safety measures to mitigate noise exposure in such work environments is crucial.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 2","pages":"12"},"PeriodicalIF":2.7,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-linear associations of blood volatile organic compounds (VOCs) with sleep health and mortality in American adults: data from the National health and nutrition examination survey (NHANES) 2007-2012.","authors":"Ming Chen, Yongshi Wang, Yi He, Ying Pang, Lili Tang","doi":"10.1007/s00420-025-02194-z","DOIUrl":"10.1007/s00420-025-02194-z","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to shed light on the potential relationships between blood volatile organic compounds (VOCs) and sleep health as well as mortality.</p><p><strong>Methods: </strong>We employed generalized linear (GL), restricted cubic spline (RCS), weighted quantile sum (WQS), quantile-based g-calculation (QGC), and Bayesian kernel machine regression (BKMR) models to assess the relationship between blood VOCs-including bromoform (NHANES code: LBXVBF), bromodichloromethane (LBXVBM), chloroform (LBXVCF), dibromochloromethane (LBXVCM), and methyl tert-butyl ether (LBXVME)-and sleep health indicators (trouble sleeping, sleep disorders, and insufficient (< 6 h/day) or excessive (> 9 h/day) sleep) in participants from the NHANES 2007-2012. The Cox proportional hazards regression model was also used for survival analysis.</p><p><strong>Results: </strong>The baseline profile categorized by sex showed that women had a higher prevalence of trouble sleeping, whereas men were more prone to insufficient sleep. We did not observe significant linear-correlations between VOCs and both increased sleep duration and poor sleep patterns, as shown by the weighted linear/logistic regression models. The RCS regression model indicated significant non-linear relationships (P for non-linear < 0.05) between certain VOC and sleep health. Adjusted QGC analysis highlighted LBXVBF as a crucial factor related to poor sleep quality (weighted 0.733). The BKMR analysis showed a positive trend between VOC levels (55th to 75th percentiles) and poor sleep pattern. Furthermore, the adjusted COX-RCS analysis identified LBXVME (P for non-linear = 0.0359) as a risk factor for all-cause mortality.</p><p><strong>Conclusions: </strong>This study investigated the non-linear association between VOC exposure and sleep function, suggesting that VOC exposure may be linked to poor sleep patterns among U.S. adults.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 2","pages":"13"},"PeriodicalIF":2.7,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review update of organisational-level mental health promotion interventions: evidence from healthcare, construction, and telework-based mobile work settings.","authors":"Eleftherios Giovanis, Oznur Ozdamar, Birgit Aust, Johanna Cresswell-Smith, Arlinda Cerga Pashoja, Caleb Leduc, Andrea Sinesi, Carolina Piña, Chantal Van Audenhove, Gentiana Qirjako, Victoria Ross, Margaret Kenneally, Hanna Reich, Evelien Coppens, Virgínia da Conceição, Helena Pardina Torner, Sevim Mustafa, György Purebl, Ainslie O'Connor, Joana Bücker, Silvia Riva, Alexandra Perez T Seyen, Ella Arensman, Pedro Lobo","doi":"10.1007/s00420-025-02193-0","DOIUrl":"10.1007/s00420-025-02193-0","url":null,"abstract":"<p><p>OBJECTIVE: This systematic review evaluates the effectiveness of organisational-level mental health promotion interventions in healthcare, construction, and Telework and ICT-based Mobile (TICTM) work, focusing on burnout, depression, anxiety, stress, and overall mental well-being. METHODS: Following PRISMA 2020 guidelines and registered with PROSPERO (CRD42024541652), we searched PubMed Medline, Scopus, Web of Science, and EBSCOHost Medline. Studies were included if they assessed organisational-level interventions targeting mental health outcomes, used quantitative methods with control groups, and applied validated measurement tools. Eligible publications were those appearing between 10 July 2021 and 30 June 2024 for healthcare and 17 May 2022 and 30 June 2024 for construction, reflecting the cut-off dates of our previous reviews, and between 1 January 2014 and 30 June 2024 for TICTM. Included studies were appraised for quality using the Quality Assessment Tool for Quantitative Studies (QATQS), and findings were synthesised using a narrative synthesis approach. RESULTS: Six controlled trials (four randomised, two non-randomised) met the inclusion criteria. The four healthcare-sector studies each reported significant improvements in at least one primary mental health outcome-burnout, depression, or stress. The construction-sector study found a short-term reduction in stress at 12 months, but this was not sustained at 24 months. The single TICTM study reported improvements in positive affect, a component of psychological well-being. CONCLUSION: This update confirmed our previous findings, showing that evidence on organisational-level interventions remains strongest in healthcare, where most studies reported improvements in at least one mental health outcome, while studies in construction and TICTM settings remain scarce. Only one study each was found for the construction sector and the TICTM setting, confirming the lack of organisational-level interventions for better mental health in sectors and settings other than healthcare. Due to this limited evidence base, no general trends can be identified. Nevertheless, the few studies suggest that organisational-level mental health promotion interventions have the potential to improve mental health outcomes in diverse settings when appropriately adapted to sector-specific conditions.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 2","pages":"10"},"PeriodicalIF":2.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12847110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146051436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indirect exposure to organophosphate pesticides and its possible growth disorders in children of farmers in Northwest Mexico.","authors":"Estefanía Ochoa-Ruiz, Aarón Israel Moreno-García, Daniel Alejandro Licea-Espinoza, Gisela Pineda-García, Krysta Paola Carranza-Ambriz, Kenya Karina Soto-Rodriguez, Arnold García-Ledezma, José Manuel Cornejo-Bravo, Ana Laura Martínez, Eleonora Mondani, Aracely Serrano-Medina","doi":"10.1007/s00420-026-02201-x","DOIUrl":"10.1007/s00420-026-02201-x","url":null,"abstract":"<p><p>PURPOSE: This study investigated the correlation between growth disorders and indirect pesticide exposure in children of farmers. METHODS: A cross-sectional study was conducted with 134 children of farmers occupationally exposed to organophosphate pesticides in the ejido Venustiano Carranza, an agricultural community in San Quintín, Baja California, Mexico. These children were compared with a control group of 56 unexposed children. Anthropometric measurements and biochemical analyses were performed in both groups to evaluate renal, hepatic, and nutritional profiles. Hormonal profiles were quantified using ELISA techniques. Cholinesterases are quantified using known colorimetric methods. Food security was also analyzed through a dietary diversity study, focusing on households. RESULTS: Indirectly exposed group showed a higher prevalence of stunting (18% vs. 16.4%) than controls. Food safety was adequate in both groups (X2 = 1.88, p = 0.597). The indirectly exposure children showed significantly higher calcium levels (9.99 ± 0.63 mg/dL) and significant increases in liver enzymes AST and GGT (p < 0.001). ALP was 1.5 times lower than in unexposed children (p < 0.001), showing a strong association with exposure time (p = 0.009). The indirectly exposed group showed lower GH and IGF-1 levels; 2.55 and 1.28 times lower than in controls, respectively. Children with indirect exposure showed a significant reduction in AChE (7211 ± 1917 vs. 8368 ± 213 U/L, p < 0.001) and an even greater decrease in BChE (6426 ± 1664 vs. 8025 ± 1462 U/L, p < 0.001). CONCLUSION: This work demonstrates an association between environmental exposure to organophosphate pesticides and children's growth and provides crucial insights for future research and policymaking.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":"99 2","pages":"11"},"PeriodicalIF":2.7,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13253838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146051392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}