International Archives of Occupational and Environmental Health最新文献

{"title":"Determinants of early employment exit and working until the statutory retirement age in poor health among workers with strenuous physical or mental work.","authors":"Sander K R van Zon, Swenne G van den Heuvel","doi":"10.1007/s00420-025-02155-6","DOIUrl":"https://doi.org/10.1007/s00420-025-02155-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study examines, among older workers with strenuous physical or mental work, the longitudinal associations between sociodemographic, work, personal, and health factors and working until the statutory retirement age categorized as working in good health, working in poor health, and employment exit before the retirement age.</p><p><strong>Methods: </strong>The study was embedded in the Study on Transitions in Employment, Ability and Motivation (STREAM) from the Netherlands. The sample consists of participants who, at any wave, were working at age 60 and for whom it was clear if and how they exited employment (n = 3969). Multinomial regression analyses were performed to examine the association between sociodemographic, work, personal, and health factors and working until the retirement age, separately for those with strenuous physical (n=658 (16.6%)) and mental work (n = 470 (11.8%)).</p><p><strong>Results: </strong>Higher mastery was associated with lower odds of working until retirement in poor health and employment exit in those with strenuous physical or mental work. Sickness absence and a poor financial situation were associated with employment exit. Only in those with strenuous physical work, sickness absence was also associated with working until retirement in poor health. Obesity was associated with higher odds of working until retirement in poor health.</p><p><strong>Conclusions: </strong>Workers with strenuous work more often work until retirement in poor health and exit employment more often than those without strenuous work. Health, mastery and workers' financial situation play a major role in whether workers can work until the statutory retirement age, and whether this is in good health.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Association between shift/night work and irregular periods and period pain among two cohorts of Australian women 16 years apart: findings from the Australian longitudinal study on women's health.","authors":"Biresaw Wassihun, Alemu Michael Waller, Leigh R Tooth","doi":"10.1007/s00420-025-02156-5","DOIUrl":"10.1007/s00420-025-02156-5","url":null,"abstract":"","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of brain and other central nervous system tumors in Danish agricultural workers.","authors":"Julie Elbaek Pedersen, Johnni Hansen","doi":"10.1007/s00420-025-02151-w","DOIUrl":"https://doi.org/10.1007/s00420-025-02151-w","url":null,"abstract":"<p><strong>Objectives: </strong>Agricultural workers exhibit a distinctive disease pattern, including an elevated incidence of brain and other central nervous system (CNS) tumors. Despite this, there is a gap in research that explores various agricultural sectors and different types of brain and CNS tumors. Hence, the objective of the current nested case-control study was to provide evidence in this area.</p><p><strong>Methods: </strong>The Danish Cancer Registry was used to identify men diagnosed with brain and CNS tumors. The study encompassed a total of 6475 cases, each matched with 100 cancer-free male controls based on the year of birth. Inclusion criteria mandated that both cases and controls were born in Denmark and acquired a documented employment history, obtained from the Supplementary Pension Fund Register.</p><p><strong>Results: </strong>We observed no association between overall brain cancer and the combined group of agricultural employees. However, an increased risk of specific cancerous gliomas of the brain in agricultural workers, including diffuse/anaplastic astrocytoma (OR = 1.37, 95% CI 1.09-1.72) and glioma malignant tumors (OR = 1.38, 95% CI 0.56-3.37) was observed. Additionally, specific agricultural sectors, including agricultural service and livestock farming, were associated with an increased risk of brain tumors. In contrast, for tumors affecting the meninges, spinal cord, cranial nerves, and other parts of the CNS, either inverse or no associations were generally observed.</p><p><strong>Conclusions: </strong>The findings indicated a heightened risk of particular cancerous brain gliomas in those employed in agriculture. Additionally, individuals employed in specific agricultural sub-sectors, such as agricultural service and livestock farming, exhibited an increased risk of brain tumors.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytogenetic evaluation of vaginal and buccal epithelium of pregnant women living in conditions of radioactive, chemical and combined environmental contamination.","authors":"Anton V Korsakov, Alexandra S Domakhina, Vladislav P Troshin, Olga Yu Milushkina","doi":"10.1007/s00420-025-02144-9","DOIUrl":"10.1007/s00420-025-02144-9","url":null,"abstract":"<p><strong>Introduction: </strong>Many pollutants constantly worsen the ecological situation, thereby causing irreparable harm to the health of the population. Technogenic impact on the biosphere has become one of the significant factors dictating our conditions of existence on Earth.</p><p><strong>Purpose of the study: </strong>to conduct a comparative analysis of the frequency of cytogenetic abnormalities, indicators of proliferation disorders and nuclear destruction of vaginal and buccal epithelium of pregnant women 26-33 years old living in conditions of radioactive, chemical and combined environmental contamination of the Bryansk region.</p><p><strong>Methods: </strong>micronucleus test, staining method by Kvik, fluorescence method, immunocytochemistry method, Shapiro-Wilk test, Mann-Whitney U test.</p><p><strong>Results: </strong>the frequency of cytogenetic abnormalities, indicators of proliferation disorders and nuclear destruction in the vaginal epithelium of pregnant women living in areas of radioactive, chemical and combined environmental contamination is 1.3-4.9 times higher, and in the buccal epithelium 1.6-7.8 times higher compared to ecologically safe (control) areas (p < 0.01-0.001). The combined effect of radioactive contamination and chemical pollution resulted in a significantly higher (increase from 12.8% to 81.4% in vaginal epithelium and from 22.6% to 2.3 times in buccal epithelium) frequency of cells with micronuclei, cells with protrusions, binuclear cells, cells with double nuclei, as well as cells with karyopyknosis and karyolysis in pregnant women compared to areas with only one pollution factor.</p><p><strong>Conclusion: </strong>The results demonstrate the synergistic effects of radiation contamination and chemical pollution on the cytogenetic status of pregnant women.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"475-486"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between exposure to air pollution and risk of Dyssomnia: a systematic review and meta-analysis.","authors":"Zhiqiu Cao, Xintao Shi, Li Sun, Zhanhong Fan, Akinyemi Lydia Idowu, Feng Zhang","doi":"10.1007/s00420-025-02137-8","DOIUrl":"10.1007/s00420-025-02137-8","url":null,"abstract":"<p><strong>Background: </strong>Typically affecting people's quality of life, dyssomnia is among the most prevalent chronic illnesses worldwide. A positive correlation between air pollution and dyssomnia has been demonstrated by epidemiological research. However, no meta-analyses evaluating the relationship between the prevalence of dyssomnia in people of all ages and air pollutants (PM_2.5, PM₁₀, NO₂, SO₂, and O₃) were found.</p><p><strong>Objectives: </strong>Conduct a meta-analysis utilizing data from current studies (until 2024) to provide reliable insights into the relationship between air pollution exposure and the likelihood of dyssomnia prevalence.</p><p><strong>Methods: </strong>We systematically searched three databases for studies on air pollution and dyssomnia up to January 15, 2024. Random-effects models were used to estimate the pooled odds ratios (ORs) and 95% confidence intervals (95% CIs). Subgroup analyses, funnel plots, and meta-regression analyses were also performed.</p><p><strong>Results: </strong>There were 11 studies from 4 different nations that involved 3,328,183 participants in total. The odds ratios (ORs) for PM_2.5 and PM₁₀ were 1.29 (1.16-1.44) and 1.13 (1.03-1.23) per 10 µg/m³ increase in pollutants, respectively. The OR per 10 µg/m³ increment of gaseous pollutants were 1.06 (1.00-1.12) for NO₂ and 1.16 (1.04-1.31) for O₃. No significant association was observed between SO₂ and dyssomnia. Adults are more sensitive to air pollution than children or adolescents for that the effects of PM_2.5、PM₁₀ and SO₂ were significantly stronger in adults than children or adolescents. The effect of air pollution on dyssomnia was more significant in developed countries than in developing countries. There was a difference in the subgroup test for PM₁₀ between developed and developing countries.</p><p><strong>Conclusion: </strong>This meta-analysis implies the relationship between the air pollution and dyssomnia. Economic status and age may influence the effect. It was suggested to provide guidance for disease prevention and explored potential avenues for further research.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"369-384"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting prolonged work absence due to musculoskeletal disorders: development, validation, and clinical usefulness of prognostic prediction models.","authors":"Tarjei Rysstad, Margreth Grotle, Adrian C Traeger, Lene Aasdahl, Ørjan Nesse Vigdal, Fiona Aanesen, Britt Elin Øiestad, Are Hugo Pripp, Gwenllian Wynne-Jones, Kate M Dunn, Egil A Fors, Steven J Linton, Anne Therese Tveter","doi":"10.1007/s00420-025-02129-8","DOIUrl":"10.1007/s00420-025-02129-8","url":null,"abstract":"<p><strong>Purpose: </strong>Given the lack of robust prognostic models for early identification of individuals at risk of work disability, this study aimed to develop and externally validate three models for prolonged work absence among individuals on sick leave due to musculoskeletal disorders.</p><p><strong>Methods: </strong>We developed three multivariable logistic regression models using data from 934 individuals on sick leave for 4-12 weeks due to musculoskeletal disorders, recruited through the Norwegian Labour and Welfare Administration. The models predicted three outcomes: (1) > 90 consecutive sick days, (2) > 180 consecutive sick days, and (3) any new or increased work assessment allowance or disability pension within 12 months. Each model was externally validated in a separate cohort of participants (8-12 weeks of sick leave) from a different geographical region in Norway. We evaluated model performance using discrimination (c-statistic), calibration, and assessed clinical usefulness using decision curve analysis (net benefit). Bootstrapping was used to adjust for overoptimism.</p><p><strong>Results: </strong>All three models showed good predictive performance in the external validation sample, with c-statistics exceeding 0.76. The model predicting > 180 days performed best, demonstrating good calibration and discrimination (c-statistic 0.79 (95% CI 0.73-0.85), and providing net benefit across a range of decision thresholds from 0.10 to 0.80.</p><p><strong>Conclusions: </strong>These models, particularly the one predicting > 180 days, may facilitate secondary prevention strategies and guide future clinical trials. Further validation and refinement are necessary to optimise the models and to test their performance in larger samples.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"385-397"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of ambient air pollution exposure to fine particulate matter and its chemical constituents before and during pregnancy with the risk of full-term small for gestational age: a retrospective cohort study.","authors":"Tingrong Wang, Hanping Ma, Rui Li, Donghua Li, Tianshan Shi, Zhenjuan Li, Zixuan Zou, Xiaowei Ren","doi":"10.1007/s00420-025-02141-y","DOIUrl":"10.1007/s00420-025-02141-y","url":null,"abstract":"<p><strong>Objective: </strong>In the current study, we explored the associations between exposure to fine particulate matter (PM_2.5) constituents and full-term small for gestational age (SGA) in different periods.</p><p><strong>Methods: </strong>We included 155,897 participants, and matched the exposure concentrations of PM_2.5 and its constituents [sulfate (SO₄^2-), nitrate (NO₃^-), ammonium (NH₄⁺), organic matter (OM), and black carbon (BC)] according to participants' geographical location. To explore the associations of prenatal exposure to PM_2.5 and its constituents with the risk of full-term SGA, we used logistic regression, restricted cubic spline regression (RCS) and quartile g-computation (QGCOMP).</p><p><strong>Results: </strong>We found that individual exposure to PM_2.5 and its constituents was positively associated with the risk of full-term SGA (P < 0.05), whether in the year before pregnancy or the entire pregnancy. These associations were more pronounced in the second trimester. We found that the risk of full-term SGA was positively and linearly related to the concentrations of PM_2.5 and its constituents (P_overall < 0.05, P_nonlinear > 0.05). The associations of PM_2.5 and its constituents with full-term SGA were stronger in multiparous mothers. Moreover, full-term SGA was associated with exposure to mixtures of SO₄^2-, NO₃^-, NH₄⁺, OM, and BC before pregnancy and in the second and third trimester. Among these, BC was positively associated with full-term SGA at each of the aforementioned stages.</p><p><strong>Conclusions: </strong>The risk of full-term SGA was positively and linearly related to concentrations of PM_2.5 and its constituents, and these associations were more pronounced in the second trimester. BC was the most hazardous constituent of PM_2.5 that was associated with full-term SGA.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"437-450"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-respiratory health risks and mortality associated with fighting bushfires (wildfires): a systematic review.","authors":"Asmare Gelaw, Win Wah, Deborah C Glass, Malcolm R Sim, Ryan Hoy, Janneke Berecki-Gisolf, Karen Walker-Bone","doi":"10.1007/s00420-025-02138-7","DOIUrl":"10.1007/s00420-025-02138-7","url":null,"abstract":"<p><strong>Background: </strong>Bushfires (also known as wildland or forest fires) expose emergency responders to occupational hazards under exceptional circumstances. Whilst the health impacts of structural firefighting have been studied, less is known about the non-respiratory health impacts or risk of mortality amongst bush firefighters, who can be volunteers. More information about health risks is needed to generate effective prevention strategies.</p><p><strong>Objective: </strong>To critically evaluate and synthesise the published evidence about the non-respiratory health risks and risk of mortality associated with bushfire fighting.</p><p><strong>Methods: </strong>A systematic literature search was conducted in Medline, Scopus, and Embase to identify studies evaluating morbidity or mortality or associated risk factors among bushfire fighters. The quality of included studies was evaluated twice independently using a specific quality assessment tool.</p><p><strong>Results: </strong>Twenty-seven studies were included. 11(41%) were assessed as moderate quality and 16(59%) as low quality. There is a growing body of evidence for adverse short-term impacts of bushfire fighting on mental health and injuries. Linkage studies showed that volunteer firefighters had lower mortality and cancer risk in their late forties compared to the general population.</p><p><strong>Conclusion: </strong>Most studies relied on cross-sectional and retrospective designs without comparison groups, limiting the ability to draw robust conclusions. It is essential to conduct higher-quality research using prospective designs and longer-term follow-up to better understand the health outcomes of bushfire fighting, particularly given the anticipated increase in the frequency and severity of bushfires.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"343-367"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid work and mental distress: a cross-sectional study of 24,763 office workers in the Norwegian public sector.","authors":"Lorena Edith Trevino Garcia, Jan Olav Christensen","doi":"10.1007/s00420-025-02136-9","DOIUrl":"10.1007/s00420-025-02136-9","url":null,"abstract":"<p><strong>Objective: </strong>Few studies have investigated the relationship between post-pandemic hybrid work-from-home (WFH), mental health, and work-life balance. We examined the association between hybrid WFH, mental distress, availability demands, work-life conflict, and life-work conflict.</p><p><strong>Methods: </strong>Data from 24,763 office workers in the public sector in Norway were analyzed by linear and logistic regressions.</p><p><strong>Results: </strong>Employees practicing flexible hybrid WFH (i.e., when needed/desired) were less likely to report mental distress (measured by the Hopkins Symptom-Checklist; HSCL-5) than those not practicing WFH. WFH being self-chosen was associated with less distress. Flexible WFH was also associated with availability demands, work-life conflict, and life-work conflict, which were, in turn, linked to distress. The risk of distress increased with the number of weekly days of flexible WFH. Workers with fixed agreements to regularly WFH did not report significantly less distress than those with no WFH. However, fixed WFH was associated with lower availability demands, not with work-life conflict, and was more often self-chosen than flexible WFH.</p><p><strong>Conclusion: </strong>Flexible WFH may alleviate distress but may also indicate attempts to cope with taxing availability demands, and may even introduce stressors that could reverse beneficial effects. Our results should motivate nuanced, multifactorial assessments of WFH in organizational practice and research.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"399-407"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) study: a seven- and twelve-year prospective analysis of occupational exposures and health outcomes among police officers.","authors":"John M Violanti, Desta Fekedulegn, Cecil M Burchfiel, Erin McCanlies, Samantha K Service, Anna Mnatsakanova, Ja K Gu, Penelope Allison, Micheal E Andrew, Luenda E Charles","doi":"10.1007/s00420-025-02142-x","DOIUrl":"10.1007/s00420-025-02142-x","url":null,"abstract":"<p><strong>Objective: </strong>Overall, police officers have higher rates of several adverse health conditions (e.g., cardiovascular health profiles and post-traumatic stress disorder (PTSD)) compared to persons in many other occupations. Our objective was to conduct a comparative study of occupational exposures and health outcomes among police officers across: (a) a 7-year period, from the baseline examination (2004-2009) to the 1st follow-up examination (2011-2015) and (b) a 12-year period, from baseline to the 2nd follow-up examination (2015-2019).</p><p><strong>Methods: </strong>Participants were from the Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) Study. Variables were assessed through self-report, standardized validated questionnaires, or standardized medical procedures. We computed the 7- and 12-year changes in mean values (for continuous/numeric variables) or prevalence (for categorical variables) and the corresponding 95% confidence intervals (CIs) using MIXED and GENMOD procedures in SAS.</p><p><strong>Results: </strong>Occupational stress significantly increased over 12 years [3.4; (95% CI 1.2, 5.6)]. The percentage of officers who reported excellent/very good health significantly decreased across both time periods: [- 11.8%; (- 17.8, - 5.9)] across seven years and [- 17.3%; (- 24.2, - 10.4)] across 12 years. The prevalence of metabolic syndrome increased over seven years [10.7%; (5.3-16.0)] and over 12 years [7.4%; (0.1-14.0)]. Abdominal obesity and glucose intolerance significantly increased over both time periods while hypertension and elevated triglyceride levels increased slightly but not significantly over both time periods.</p><p><strong>Conclusion: </strong>Occupational stressors and some health outcomes of officers worsened over time indicating the need for self-health monitoring and wellness programs for police.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"451-465"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12238166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}