The role of personal risk factors in the occurrence of the hand-arm vibration syndrome: a pooled analysis of individual data from Italian cross-sectional and cohort studies.

IF 2.4 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Archives of Occupational and Environmental Health Pub Date : 2025-10-01 Epub Date: 2025-09-09 DOI:10.1007/s00420-025-02169-0

Massimo Bovenzi, Federico Ronchese, Francesca Larese Filon, Enrico Marchetti, Angelo Tirabasso, Carlotta Massotti, Marco Tarabini

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引用次数: 0

Abstract

Purpose: To investigate the role of personal risk factors in the occurrence of the vascular, neurological and fibroproliferative disorders of the hand-arm vibration syndrome (HAVS) in workers groups exposed to hand-transmitted vibration (HTV).

Methods: HAVS prevalence and incidence data were pooled across a series of cross-sectional studies (total sample: 1272 HTV workers, 579 controls) and prospective cohort studies (total sample: 377 HTV workers, 138 controls) conducted in Central and North-Eastern Italy. The pooled studies included detailed individual-level information about HTV exposure, personal risk factors, medical comorbidities and HAVS disorders. Vibration exposures were evaluated according to the recommendations of ISO standards.

Results: The pooled studies revealed dose-response relationships between HTV exposure and the vascular and neurological components of HAVS. Older age, excessive alcohol intake, and comorbid conditions such as metabolic disorders, traumas/surgery to the neck and upper limbs, and disorders of the cervical spine were differentially associated with HAVS outcomes. Higher BMI had a protective effect on vascular disorders. Data modelling showed no significant interactions between HTV exposure and personal risk factors in the occurrence of upper limb disorders.

Conclusions: The pooled analysis of epidemiological studies with individualised work, personal, and medical data confirmed that HTV exposure is a primary occupational risk factor for disorders in the fingers and hands of users of vibratory tools. Ageing and some personal factors connected to lifestyles and comorbidities were associated with an increased risk for upper limb disorders in HTV workers. Occupational and personal risk factors tended to contribute independently of each other to adverse outcomes in operators of hand-held vibrating machinery.

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个人危险因素在手臂振动综合征发生中的作用：来自意大利横断面和队列研究的个人数据汇总分析。

目的：探讨个人危险因素在手传播振动（HTV）工人手臂振动综合征（HAVS）血管、神经和纤维增殖性疾病发生中的作用。方法：在意大利中部和东北部进行了一系列横断面研究（总样本：1272名HTV工作者，579名对照）和前瞻性队列研究（总样本：377名HTV工作者，138名对照），汇总了HAVS患病率和发病率数据。汇集的研究包括关于HTV暴露、个人危险因素、医疗合并症和HAVS疾病的详细个人信息。根据ISO标准的建议评估振动暴露。结果：综合研究揭示了HTV暴露与HAVS的血管和神经成分之间的剂量-反应关系。年龄较大、过量饮酒以及代谢紊乱、颈部和上肢创伤/手术以及颈椎疾病等共病与HAVS结果存在差异相关。较高的BMI对血管疾病有保护作用。数据建模显示，HTV暴露与上肢疾病发生的个人危险因素之间没有显著的相互作用。结论：对个体化工作、个人和医疗数据的流行病学研究进行汇总分析，证实高温高压暴露是振动工具使用者手指和手部疾病的主要职业风险因素。老龄化和一些与生活方式和合并症有关的个人因素与HTV工人上肢疾病的风险增加有关。职业和个人风险因素往往相互独立地影响手持振动机械操作人员的不良后果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Archives of Occupational and Environmental Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

5.60

自引率

6.70%

发文量

127

审稿时长

3 months

期刊介绍： International Archives of Occupational and Environmental Health publishes Editorials, Review Articles, Original Articles, and Letters to the Editor. It welcomes any manuscripts dealing with occupational or ambient environmental problems, with a special interest in research at the interface of occupational health and clinical medicine. The scope ranges from Biological Monitoring to Dermatology, from Fibers and Dust to Human Toxicology, from Nanomaterials and Ultra-fine Dust to Night- and Shift Work, from Psycho-mental Distress and Burnout to Vibrations. A complete list of topics can be found on the right-hand side under For authors and editors. In addition, all papers should be based on present-day standards and relate to: -Clinical and epidemiological studies on morbidity and mortality -Clinical epidemiological studies on the parameters relevant to the estimation of health risks -Human experimental studies on environmental health effects. Animal experiments are only acceptable if relevant to pathogenic aspects. -Methods for studying the topics mentioned above.