International Journal of Adhesion and Adhesives最新文献

{"title":"Role of bolt pretension in determining stress and load-bearing capacity of hybrid joints","authors":"Tobias Evers ,&nbsp;Marc Aurel Viehöfer ,&nbsp;Morten Voß ,&nbsp;Till Vallée ,&nbsp;Koichi Yokozeki","doi":"10.1016/j.ijadhadh.2025.103961","DOIUrl":"10.1016/j.ijadhadh.2025.103961","url":null,"abstract":"<div><div>This study investigated the effect of bolt pretension on the load-bearing capacity and stress distribution of hybrid joints combining adhesive bonding and mechanical fastening, using two brittle epoxies (SW7240 and DP460) and one ductile polyurethane (SF479). Experimental results showed that the brittle epoxies consistently maintained a load capacity above 300 kN, even at low pretension levels (10% of the maximum 65 kN), whereas the polyurethane exhibited marked sensitivity to pretension, with its load capacity increasing from 220 kN at 10% pretension to approximately 300 kN at full pretension. Despite these differences, all adhesives displayed brittle failure, characterized by cohesive failure near the adhesive layer’s surface. Material characterization revealed linear-elastic behavior for the epoxies and bi-linear behavior for the polyurethane, which allowed for effective stress redistribution. Multiaxial stress analysis indicated that pretension-induced compressive stresses critically enhanced the polyurethane’s performance by shifting the stress state to delay failure, while localized stress concentrations limited the benefits of pretension for the epoxies. Finite element analysis supported these observations, showing that pretension had minimal effect on the concentrated tensile stresses in epoxy-bonded joints but improved stress distribution in polyurethane-bonded joints, enabling them to sustain higher loads without exceeding failure thresholds. These findings emphasize the importance of adhesive selection and the interaction between pretension and stress management, with brittle epoxies offering robust performance irrespective of pretension, while ductile polyurethanes leverage pretension to achieve enhanced load-bearing capacity under combined loading conditions.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"140 ","pages":"Article 103961"},"PeriodicalIF":3.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143518882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An analytical procedure for failure and stiffness prediction of glued-in rod timber connections","authors":"S. Karen Alavi,&nbsp;Hamid R. Valipour,&nbsp;Mark A. Bradford","doi":"10.1016/j.ijadhadh.2025.103992","DOIUrl":"10.1016/j.ijadhadh.2025.103992","url":null,"abstract":"<div><div>Glued-in rod (GiR) timber joints, featuring a composition of a rod, adhesive (glue), and timber, play a pivotal role within the mass timber construction industry where the performance of the GiR connections is imperative for the success of massive timber-based structural systems. However, the intricate mechanical complexities inherent in the load-displacement behaviour of the timber/adhesive joints present significant challenges in the accurate analysis and design of the GiR connections. This article endeavours to use the theory of elasticity and fracture mechanics to derive an analytical procedure for assessing the stiffness and loading capacity of the single GiR joints subjected to pull-pull, pull-push, rod-pull, and wood-pull loading configurations. In the proposed analytical model, the adherents are treated as isotropic, orthotropic, or multilayer composite materials. Given the intricate anisotropic nature of the timber and the composition of the GiR connections, a judicious combination of failure criteria inspired by continuum damage mechanics or fracture mechanics is adopted, to effectively capture the peak load associated with a wide range of failure modes. The accuracy of the proposed analytical model is evaluated through comparison with the laboratory test data, Volkersen's theory, and EN1995-1-1 models, providing insights for efficient analysis and design of timber connections with GiR.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"140 ","pages":"Article 103992"},"PeriodicalIF":3.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardanol-induced surface rearrangement of fluorine in polyurethane acrylic coatings to achieve self-cleaning and anti-graffiti properties","authors":"Jiaxing Zhang ,&nbsp;Zhao Zhang ,&nbsp;Hui Chang ,&nbsp;Yangyi Chen","doi":"10.1016/j.ijadhadh.2025.103995","DOIUrl":"10.1016/j.ijadhadh.2025.103995","url":null,"abstract":"<div><div>In this paper, a UV-curable solvent-free biomass polyurethane acrylic material was prepared by a two-step method, including the synthesis of cardanol-based polymerizable monomer and cardanol-based resins. This resin could form excellent self-cleaning and anti-fingerprint coatings after suffering from UV curing. It was found that the cardanol alkyl chain broke the hydrogen-fluorine (H⋅⋅⋅F) bond between the F atom of perfluoroalkyl acrylate and H-N of polyurethane in the coating. And cardanol alkyl chain synergistically induced the directional arrangement of F atoms to the surface, which improved the hydrophobic properties of the coating. This coating has good resistance to common pollutants such as water, ethanol, milk, coffee, dust, and fingerprints, and is suitable for various substrates such as sheet iron, and PET sheet. Due to the high degree of crosslinking in the coating, it can effectively prevent the penetration of acidic and alkaline substances, maintaining good self-cleaning performance even after immersion in a solution of strong acids or alkalis (pH 1–13) for 72 h. The use of cardanol-induced coating fluorine atom surface rearrangement technology can significantly reduce the amount of fluorine and also provide new ideas for the design of self-cleaning and anti-graffiti materials.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"140 ","pages":"Article 103995"},"PeriodicalIF":3.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of preparation burs on the adhesion of resin-based composite and glass-ionomer to enamel, superficial and deep dentin - Diamond, carbide or Arkansas bur?","authors":"Furkan Dere ,&nbsp;Nadin Al-Haj Husain ,&nbsp;Kiren Jan Mätzener ,&nbsp;Yuliya Fast ,&nbsp;Luiza Freitas Brum Souza ,&nbsp;Tan Fırat Eyüboğlu ,&nbsp;Mutlu Özcan","doi":"10.1016/j.ijadhadh.2025.103993","DOIUrl":"10.1016/j.ijadhadh.2025.103993","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to determine whether the bur type affects the adhesion of resin-based composite and glass-ionomer restorative materials to enamel and dentin at different depths.</div></div><div><h3>Methods</h3><div>Wisdom molar teeth (N = 216) were prepared using three different types of burs: a) extra-fine diamond-coated bur, b) carbide bur (16–20 blade) and c) Arkansas bur at three occlusal depth levels: enamel, superficial dentin, and deep dentin. Specimens were then randomly assigned to receive either resin composite (RC) or glass-ionomer (GI). Half of the specimens were tested 24 h after bonding (dry) while the other half after thermocycling (500 cycles, 5–55 °C) for shear bond strength in a universal testing machine. Data were analyzed using Kruskal-Wallis, Wilcoxon rank-sum test with Bonferroni adjustment (α = 0.05). Additionally, Weibull modulus for each group was calculated to assess adhesion reliability using the various bur types on different substrates.</div></div><div><h3>Results</h3><div>The bur, restorative material type and aging affected the bond strength results (p&lt;0.05) and the interaction terms were significant (p&lt;0.05). In dry conditions, bur type did not affect the bond strength results (MPa) significantly on enamel and superficial dentin for both RC (5.73 ± 4.4–11.99 ± 7.62) and GI (4.93 ± 2.8–2.73 ± 0.75) (p&gt;0.05). On deep dentin, carbide bur performed significantly better for RC (10.44 ± 4.08) than other bur types (6.06 ± 2.36–6.56 ± 3.58) (p&lt;0.05). After thermocycling, bur type did not affect the bond strength results (MPa) significantly on enamel for both RC (13.19 ± 4.9–13.06 ± 5.57) and GI (4.50 ± 3.76–4.90 ± 3.11) (p&gt;0.05). While on superficial dentin, bur type did not affect the bond strength results for RC (10.17 ± 5.98–7.07 ± 3.58), for GI diamond bur resulted in significantly lower bond strength (1.65 + 1.01) (p&lt;0.05). On deep dentin, bur type did not affect the results for GI (3.24 ± 2.32–4.48 ± 2.26) but diamond bur resulted in higher bond strength (12.62 ± 6.47) than those of other burs (6.62 ± 3.05–7.14 ± 5.12) (p&lt;0.05). Weibull modulus after thermocycling was the highest for Arkansas in RC (3.23) compared to other bur-material combinations (<em>m</em> = 1.6–2.9). After thermocycling, adhesion to enamel was not affected but independent from bur-material combinations in superficial and deep dentin increased significantly (p&lt;0.05).</div></div><div><h3>Significance</h3><div>Tooth preparation on enamel does not benefit from the use of different bur types for increased adhesion both with resin composite and glass-ionomer. While a diamond bur cannot be recommended for glass-ionomer on superficial dentin, the same bur type enhances adhesion on deep dentin.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"140 ","pages":"Article 103993"},"PeriodicalIF":3.2,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How can calcium silicate-based sealers impact the mineral phase of root dentin after the use of intracanal medications? A chemical and spectroscopic analysis","authors":"Iago Ramirez ,&nbsp;Guilherme Nilson Alves dos Santos ,&nbsp;Guilherme Piedade Assed de Castro ,&nbsp;Débora Fernandes Costa Guedes ,&nbsp;Manoel Damião Sousa-Neto ,&nbsp;Ana Paula Ramos ,&nbsp;Fabiane Carneiro Lopes-Olhê ,&nbsp;Jardel Francisco Mazzi-Chaves","doi":"10.1016/j.ijadhadh.2025.103991","DOIUrl":"10.1016/j.ijadhadh.2025.103991","url":null,"abstract":"","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"140 ","pages":"Article 103991"},"PeriodicalIF":3.2,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of the joining temperature on the tensile–shear mechanical properties of clinch-adhesive joints in steel and aluminum alloy sheets","authors":"Hailun Zhang,&nbsp;Weimin Zhuang,&nbsp;Jianing Shi","doi":"10.1016/j.ijadhadh.2025.103986","DOIUrl":"10.1016/j.ijadhadh.2025.103986","url":null,"abstract":"<div><div>Given the temperature dependence of the performance of polymer-based adhesives, a warm clinch-adhesive joining technique, aimed at enhancing the formation quality of dissimilar material joints between steel and aluminum, was proposed in this study. The temperature-sensitive epoxy resin Araldite<span><math><msup><mrow></mrow><mrow></mrow></msup></math></span>® 2015 was selected as the adhesive. Clinching was implemented at four different process temperatures, i.e., <span><math><mrow><mn>2</mn><msup><mrow><mn>5</mn></mrow><mrow><mo>∘</mo></mrow></msup></mrow></math></span>C, <span><math><mrow><mn>5</mn><msup><mrow><mn>0</mn></mrow><mrow><mo>∘</mo></mrow></msup></mrow></math></span>C, <span><math><mrow><mn>6</mn><msup><mrow><mn>5</mn></mrow><mrow><mo>∘</mo></mrow></msup></mrow></math></span>C and <span><math><mrow><mn>8</mn><msup><mrow><mn>0</mn></mrow><mrow><mo>∘</mo></mrow></msup></mrow></math></span>C, and the mechanical response of the joints was comprehensively assessed through tensile–shear tests at room temperature. Additionally, a finite element model of the clinch-adhesive joints subjected to tensile–shear loading at room temperature was developed to investigate the failure mechanism. The results revealed that increasing the process temperature to <span><math><mrow><mn>8</mn><msup><mrow><mn>0</mn></mrow><mrow><mo>∘</mo></mrow></msup></mrow></math></span>C effectively promoted plastic flow of the adhesive layer and significantly enhanced the formation of mechanical interlocks, with an increase in the interlock depth of 22.9%; furthermore, the energy absorption capacity of the joint upon adhesive layer failure increased by 53.9%, and the peak load capacity increased by 16.8%.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"140 ","pages":"Article 103986"},"PeriodicalIF":3.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"n-hexane influence on canola oil adhesion and volumetric properties","authors":"Katarzyna Szymczyk ,&nbsp;Anna Zdziennicka ,&nbsp;Bronisław Jańczuk ,&nbsp;Janusz Lubas ,&nbsp;Artur Jaworski ,&nbsp;Hubert Kuszewski ,&nbsp;Paweł Woś ,&nbsp;Rafał Longwic ,&nbsp;Przemysław Sander","doi":"10.1016/j.ijadhadh.2025.103990","DOIUrl":"10.1016/j.ijadhadh.2025.103990","url":null,"abstract":"<div><div>Due to the growing interest in the application of canola oil (RO) as a fuel for diesel engines, studies of the adhesion and volumetric properties of mixture of RO with <em>n</em>-hexane (Hex) were carried out. They were based on the measurements of the surface tension, density, viscosity, and contact angle of the RO + Hex mixtures in the range of <em>n</em>-hexane mole fraction from 0 to unity on the polytetrafluoroethylene (PTFE), poly(methyl methacrylate) (PMMA) and the steel surfaces. The properties of the mixed <em>n</em>-hexane and canola oil layer on the steel surface were also determined by measurements of the contact angle for such model liquids as water, formamide and diiodomethane on both balls and a flat steel surface covered with this layer. Moreover, lubricating properties, based on the value of the scuffing load, for RO and its mixtures with Hex in relation to the diesel fuel (DF) were determined. Taking into account the contact angles values, the surface tension components and parameters of the RO + Hex mixtures as well as the steel covered by the layer of this mixture were determined and next used for the adhesion work of <em>n</em>-hexane and canola oil to PTFE and steel considerations. As follows this mixture at the proper composition has good lubrication properties. However, the analysis of the obtained values of the surface tension, density and viscosity of the mixture of canola oil and <em>n</em>-hexane showed that with the appropriate selection of its composition, properties similar to those of diesel fuel can be obtained.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"140 ","pages":"Article 103990"},"PeriodicalIF":3.2,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of thermal and humidity conditions on structural epoxy adhesives during medium-term exposure","authors":"Marcin Kujawa ,&nbsp;Piotr Paczos ,&nbsp;Łukasz Smakosz ,&nbsp;Adam Piasecki ,&nbsp;Faizullah Jan ,&nbsp;Karol Winkelmann ,&nbsp;Viloletta Konopińska-Zmysłowska ,&nbsp;Victor A. Eremeyev","doi":"10.1016/j.ijadhadh.2025.103981","DOIUrl":"10.1016/j.ijadhadh.2025.103981","url":null,"abstract":"<div><div>An experimental program was undertaken to evaluate the performance characteristics, strengths and limitations of two commercially available two-component structural epoxy resin adhesives under varying thermal and humidity conditions, focusing on their performance in scenarios relevant to engineering applications. The following adhesives were selected for investigation, 3M Scotch DP490 and DP125 Gray. In practice, DP490, a high-rigidity epoxy, is primarily used for bonding small, unpainted metal parts, as well as metal to glass, ceramics, and stone. DP125 Gray, on the other hand, is a more flexible system, typically used for bonding metal to glass, glass to plastic, and painted or powder-coated metals. The selected adhesives were subjected to elevated temperatures (40 °C, 60 °C, 80 °C), hygrothermal conditioning (24h <span><math><mo>→</mo></math></span> 4h 40 °C/90%RH; 8h -20 °C; 8h 70 °C/90%RH; 4h 20 °C/60%RH) and freeze-thaw cycles (24h <span><math><mo>→</mo></math></span> 16h -20 °C; 8h 20 °C/45%RH). A medium-term exposure period was adopted to more accurately simulate real-world service conditions (7, 14, 28 days). The experimental characterization of these adhesives was conducted using scanning electron microscopy (chemical composition, fracture surface analysis), standard tensile tests (Young’s modulus, tensile strength), and Shore hardness tests. SEM analysis showed that both adhesives’ chemical compositions remained unchanged after environmental exposure, moreover DP125 Gray was found to contain harmful fluorine. DP490 lost elasticity at high temperatures but gained tensile strength at lower temperatures, while DP125 Gray showed improved elasticity, strength, and Shore hardness with higher temperatures. Unfortunately, both adhesives degraded at high humidity. The research described in this paper is part of a broader research program related to the application of bonding in the manufacturing of complex thin-walled profiles.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"139 ","pages":"Article 103981"},"PeriodicalIF":3.2,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143420666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adhesive geometry dependence of JIS adhesive strength expressed as average stress and countermeasure based on ISSF","authors":"Nao-Aki Noda ,&nbsp;Rei Takaki ,&nbsp;Yasuaki Suzuki ,&nbsp;Yasushi Takase ,&nbsp;Kazuhiro Oda","doi":"10.1016/j.ijadhadh.2025.103978","DOIUrl":"10.1016/j.ijadhadh.2025.103978","url":null,"abstract":"<div><div>The Japanese Industrial Standard (JIS) specifies the adhesive strength as an average ultimate tensile stress without considering the size effect. The prescribed JIS specimen has a smaller adhesive area, <span><math><mrow><msup><mi>A</mi><mrow><mi>J</mi><mi>I</mi><mi>S</mi></mrow></msup><mo>=</mo><msup><mrow><mo>(</mo><mrow><mn>12.7</mn><mi>m</mi><mi>m</mi></mrow><mo>)</mo></mrow><mn>2</mn></msup></mrow></math></span>. In this paper, therefore, the reduction of the average adhesive strength is investigated for large adhesive areas <span><math><mrow><mi>A</mi><mo>≫</mo><msup><mi>A</mi><mrow><mi>J</mi><mi>I</mi><mi>S</mi></mrow></msup></mrow></math></span>. The discussion is based on the results that the adhesive strength can be expressed as a constant ISSF (Intensity of the Singular Stress Field), as shown in previous studies. Even for ductile resin, the elastic behavior of the adhesive layer is confirmed, as well as small-scale yielding, showing the validity of the ISSF obtained by elastic analysis. Numerical simulation shows that the average adhesive strength varies depending on the adhesive geometry. With a tenfold increase in the adhesive geometry, the adhesive strength decreases to 50 % of the JIS strength, and with a hundredfold increase, the adhesive strength decreases to 20 % of the JIS strength. For large adhesive areas, the JIS strength can be applied by using the same adhesive thickness as that for the small adhesive area specified by the JIS. This is because the ISSF of the actual product is controlled by the adhesive thickness regardless of the adhesive area.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"140 ","pages":"Article 103978"},"PeriodicalIF":3.2,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143445192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sericin and gentamicin-enhanced polyurethane-acrylate adhesives for superior adhesion, biocompatibility and antibacterial property","authors":"Sevgi Balcioglu ,&nbsp;Merve Goksin Karaaslan ,&nbsp;Ahmet Ulu ,&nbsp;Imren Ozcan ,&nbsp;Samir Abbas Ali Noma ,&nbsp;Canbolat Gurses ,&nbsp;Burhan Ates ,&nbsp;Suleyman Koytepe","doi":"10.1016/j.ijadhadh.2025.103988","DOIUrl":"10.1016/j.ijadhadh.2025.103988","url":null,"abstract":"<div><div>Bioadhesives are crucial in minimally invasive procedures but often lack biocompatibility, mechanical strength, and antimicrobial properties. Polyurethane-based adhesives, particularly UV-curable types, offer tunable properties and rapid curing. This study developed a polyurethane-acrylate adhesive system incorporating sericin and gentamicin to enhance biocompatibility and antibacterial effects for surgical and wound care applications. Sericin, a silk-derived protein, improved cell adhesion without compromising structural integrity, while 2.5 % gentamicin provided sustained antibacterial activity against <em>E. coli</em>, <em>P. aeruginosa</em>, and <em>S. aureus</em>.</div><div>The synthesis involved modifying IPDI with β-cyclodextrin, sericin, and PEG (200, 400, 600) to optimize flexibility and stability. Comprehensive characterization was conducted, including FTIR, TGA, DSC, NMR, SEM, AFM, adhesion strength, biodegradability, gentamicin release, antibacterial efficacy, and biocompatibility with L-929 fibroblast cells. Adhesion strengths were 4141.3–4474.7 kPa (PEG200), 2306–3158 kPa (PEG400), and 1690–2061 kPa (PEG600), with PEG400 providing the best balance, making IPDI-SER-P400-20-AC the optimal candidate. The adhesive exhibited 87 % cell viability (ISO 10993-5), 30 % biodegradation in four weeks, and 60 % gentamicin release within 24 h, ensuring rapid antibacterial action.</div><div>This sericinand gentamicin-enhanced bioadhesive offers a promising multifunctional platform for biomedical applications, with potential for further optimization in controlled drug release and long-term <em>in vivo</em> evaluations.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"139 ","pages":"Article 103988"},"PeriodicalIF":3.2,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}