International Journal of Adhesion and Adhesives最新文献

{"title":"Optimization of dentin bonding performance of stronger HEMA-free universal adhesives using DMSO: A 4-year in vitro study","authors":"Wendlinger M ,&nbsp;Stape Ths ,&nbsp;Cochinski Gd ,&nbsp;Cardenas Afm ,&nbsp;Siqueira Fsf ,&nbsp;M. Viviana-Mora ,&nbsp;A. Tezvergil-Mutluay ,&nbsp;A. Loguercio","doi":"10.1016/j.ijadhadh.2025.104125","DOIUrl":"10.1016/j.ijadhadh.2025.104125","url":null,"abstract":"<div><h3>Purpose</h3><div>To examine whether dimethyl sulfoxide (DMSO) would affect resin-dentin bonding of a intermediately strong and HEMA free universal adhesive after long-term aging.</div></div><div><h3>Methods</h3><div>Sixty human molars were used in this study. Forty teeth were assigned to experimental groups using a HEMA free universal adhesive (iBond Universal, Kulzer, [IBU]), and twenty teeth were used for the positive control groups with a HEMA-containing universal adhesive (Scotchbond Universal [SBU]). The IBU groups were divided according to: 1) Treatment (untreated or DMSO pretreatment) and 2) Application mode (etch-and-rinse or self-etch). For storage time, specimens from the same tooth were randomly tested at 24 h or 4 years. The restoration was performed, and the specimens were sectioned into resin-dentin bonded beams. Resin-dentin bonded beams were tested (24 h and after 4 years of water storage) for microtensile bond strength (μTBS) (0.5 mm/min) and to assess nanoleakage (NL). Data on μTBS and NL were analyzed using three-way ANOVA and Tukey's test (α = 0.05).</div></div><div><h3>Results</h3><div>After 4 years of water storage, groups without DMSO pre-treatment showed significant reductions in μTBS and increased NL, regardless of application mode (<em>p</em> &lt; 0.001). In contrast, DMSO-treated samples showed no significant reductions after 4 years, regardless of the application mode (<em>p</em> &gt; 0.05). When compared to the positive control group, the IBU untreated group exhibited significant reductions in μTBS and increased NL, regardless of the application mode (<em>p</em> &lt; 0.001). However, no significant differences were observed for IBU DMSO-pretreated samples compared to SBU, regardless of the application mode and evaluation times (<em>p</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>DMSO-wet bonding effectively enhanced and preserved the quality of resin bonds over time when using an intermediately strong HEMA free universal adhesive.</div></div><div><h3>Clinical significance</h3><div>DMSO pretreatment is a simple, practical strategy that enhances adhesive restoration durability, making it highly applicable in routine clinical practice.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104125"},"PeriodicalIF":3.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144907121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Red pine tannin extraction and green wood adhesive preparation","authors":"Salise Oktay ,&nbsp;Antonio Pizzi","doi":"10.1016/j.ijadhadh.2025.104131","DOIUrl":"10.1016/j.ijadhadh.2025.104131","url":null,"abstract":"<div><div>There are significant restrictions related to industrial applications of formaldehyde-based wood adhesives due to their formaldehyde content and fossil-based raw materials. Herein, a red pine tannin-based wood adhesive formulation was developed. First of all, red pine tannin was extracted from red pine barks by using a hot water extraction process and the Stiasny number of the extract was determined. After that, a tannin-based wood adhesive was prepared. The solid content, curing time, and viscosity of the synthesized adhesive were determined. The chemical structure and the thermal properties of the synthesized adhesive were observed by using Fourier Transformed Infrared Spectroscopy (FT-IR) and Differential scanning calorimetry (DSC) analysis, respectively. Besides, laboratory-scale particleboards were produced to determine the performance of the developed resin formulation, and the results were evaluated according to dry medium (P2 class) of European norms EN 312 (2010) standard. It is known that wood raw material, press parameters, and environmental factors affect the board's formaldehyde content as well as the binder. Therefore, although bio-based resins were used in the study, the formaldehyde content of the boards was determined by using the perforator method according to European Norm EN 12460-5. As a result, the produced bio-based boards largely met the limits of EN 312 – P2 class. In addition, the formaldehyde content of the boards was measured as 0.51 mg/100 g. The obtained test results showed that the developed tannin-based resin formulation is a potential environmentally friendly solution for the wood-based panel industry.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104131"},"PeriodicalIF":3.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144917720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonic activation enhances bond strength and epoxy resin-based sealer penetration after removal of calcium hydroxide intracanal dressing","authors":"Ana Carolina Venção ,&nbsp;Joatan Lucas de Sousa Gomes Costa ,&nbsp;Antonia Patricia Oliveira Barros ,&nbsp;João Felipe Besegato ,&nbsp;Wilfredo Gustavo Escalante-Otárola ,&nbsp;Idomeo Bonetti Filho ,&nbsp;Milton Carlos Kuga","doi":"10.1016/j.ijadhadh.2025.104133","DOIUrl":"10.1016/j.ijadhadh.2025.104133","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the effect of conventional endodontic irrigation (CEI), passive ultrasonic irrigation (PUI), and continuous ultrasonic irrigation (CUI) protocols for the removal of calcium hydroxide intracanal dressings containing either propylene glycol (PG) or methylcellulose (MC) on the adhesive interface with epoxy resin-based endodontic sealer.</div></div><div><h3>Materials and methods</h3><div>Sixty canine teeth were submitted to chemomechanical preparation and divided into two groups (n = 30) according to the intracanal dressing composition (ICD): PG or MC. After one week, each group was further divided into three subgroups (n = 10) according to the irrigation protocol used for dressing removal: CEI, PUI, or CUI. Root canals were obturated and sectioned at the cervical, middle, and apical thirds. Bond strength was evaluated using the push-out test, and tag formation was assessed by confocal laser scanning microscopy. The data were analyzed using two-way ANOVA and Tukey's test (P = 0.05).</div></div><div><h3>Results</h3><div>In the cervical and middle thirds, CUI-PG and CUI-MC showed the highest bond strength and tags extension values (<em>P</em> &lt; 0.05), but similar each other (<em>P</em> &gt; 0.05), while CEI-PG and CEI-MC showed the lowest values (<em>P</em> &lt; 0.05). In the apical third, CEI protocols also showed the lowest bond strength and tags extension values (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Ultrasonic irrigation protocols (PUI and CUI) significantly improved the bond strength and tag formation of the epoxy resin-based sealer at the dentin interface, regardless of the calcium hydroxide vehicle or root third.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104133"},"PeriodicalIF":3.5,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of a multi-functional soy protein adhesive with toughness, mildew resistance and flame retardancy by constructing multi-bond cooperation","authors":"Ye Mao ,&nbsp;Shuting Zhang ,&nbsp;Yuanwei Wang ,&nbsp;Anbo Pan ,&nbsp;Bangke Xu ,&nbsp;Genghao Zheng ,&nbsp;Xiaochun Zhang ,&nbsp;Yantao Xu","doi":"10.1016/j.ijadhadh.2025.104134","DOIUrl":"10.1016/j.ijadhadh.2025.104134","url":null,"abstract":"<div><div>Faced with petrochemical resource shortages, partially replacing aldehyde adhesives with bio-based soy protein adhesives is crucial, yet modified versions still suffer from high interfacial brittleness and inadequate anti-mildew/flame-retardant properties. This study constructed a soy protein adhesive composite system based on multiple bonding interactions, including covalent crosslinking, hydrogen bond, and ionic bond. The crosslinker triglyceride amine (TGA) crosslinked with soy protein to form a cross-linked structure; sodium alginate (SA) interacted with soy protein to form hydrogen bond; Mg²⁺ chelated with SA and soy protein to form ionic bond. Among them, covalent crosslinking served as the backbone structure, providing water resistance and strength for adhesive, while hydrogen and ionic bonds acted as sacrificial bonds, dissipating energy and improving the toughness of the adhesive. Compared to the SPI adhesive, the dry and wet shear strength of SPI/SA/Mg²⁺/TGA adhesive increased by 66.09 % and 199.07 % reaching 1.91 MPa and 0.96 MPa, respectively, and the tensile strain increased by 23.5 %–32.4 %; the moldy time improved from 2 d to more than 15 d; the limit oxygen index increased by 20.8 %–29.0 %. This modification strategy collectively enhancing bonding toughness, mildew resistance, and flame retardancy to advance industrial utilization of soy-based adhesives and sustainable development of artificial board binders.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104134"},"PeriodicalIF":3.5,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144893380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced mechanical interlocking in adhesive joints through precision-engineered surface patterns on 3D-printed PLA adherends","authors":"Nidhal Naat ,&nbsp;Khalil Hajlaoui ,&nbsp;Salah Mezlini ,&nbsp;Lucas F.M. da Silva","doi":"10.1016/j.ijadhadh.2025.104132","DOIUrl":"10.1016/j.ijadhadh.2025.104132","url":null,"abstract":"<div><div>Advancements in Additive Manufacturing (AM) have underscored the need for robust bonding strategies in 3D-printed components. Although AM enables the creation of customised interlocking joints, the interplay between printing orientation, pattern geometry, and adhesive type remains underexplored. This study investigates the effect of Square-wave (S) and Hexagonal (H) interlocking patterns, produced via Fused Deposition Modelling in edgewise (Edge) and flatwise (Flat) orientations, on the shear strength and failure mechanisms of polylactic-acid (PLA) joints bonded with cyanoacrylate (LOCTITE® 406™) or epoxy (LOCTITE® EA 3430) adhesives. PLA adherends with as-printed, S, and H patterns were fabricated in both orientations and bonded using the specified adhesives, with monolithic specimens serving as controls. Quasi-static shear tests were conducted according to the ASTM-D4501 standard. The results revealed that for the edgewise orientation, the filament paths deposited by the nozzle produced rounded walls in the interlocking features, which reduced mechanical interlocking and led to a decrease in shear strength. In contrast, the flatwise orientation more accurately preserved the designed geometries, thereby enhancing interlocking efficiency. Furthermore, cyanoacrylate bonding consistently outperformed epoxy adhesive in shear strength due to its lower viscosity. Notably, the H_Flat joints exhibited a shear strength of 30.24 ± 1.18 MPa, representing a 41 % increase over the as-printed_Flat joints (21.51 ± 3.57 MPa), a 12 % improvement compared to the S_Flat joints (27.17 ± 1.24 MPa), and an 18 % enhancement relative to the monolithic specimens (25.61 ± 0.53 MPa). Failure analysis revealed that the plastic deformation and interlayer delamination observed in the hexagonal male and female features of H_Flat joints contributed to a load redistribution, ultimately resulting in the highest load-bearing capacity among all configurations.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104132"},"PeriodicalIF":3.5,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144893381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of glycolic acid on the longevity of bond strength, enzymatic activity, and adhesive interface quality of fiberglass posts","authors":"Karen Gisselle Garay Villamayor ,&nbsp;Nathália Mancioppi Cerqueira Bellodi ,&nbsp;Juliana de Lima Gonçalves ,&nbsp;Helena Cristina de Assis ,&nbsp;Gabrielle Jacob ,&nbsp;Manoel D. Sousa-Neto ,&nbsp;Jardel Francisco Mazzi-Chaves ,&nbsp;Aline Evangelista Souza Gabriel ,&nbsp;Francisco Wanderley Garcia de de Paula e Silva ,&nbsp;Fabiane Carneiro Lopes-Olhê","doi":"10.1016/j.ijadhadh.2025.104126","DOIUrl":"10.1016/j.ijadhadh.2025.104126","url":null,"abstract":"<div><h3>Statement of problem</h3><div>Ensuring long-term bond stability between fiberglass posts and root dentin is crucial for the success of both endodontic and coronal restorations.</div></div><div><h3>Purpose</h3><div>To evaluate the effect of glycolic acid on the push-out bond strength, failure pattern, adhesive interface quality, and proteolytic activity of root dentin.</div></div><div><h3>Materials and methods</h3><div>Thirty maxillary canines were sectioned to a length of 16 mm and treated with distilled water (DW), chlorhexidine (CHX), or glycolic acid (GA) after being instrumented with Reciproc R50, obturated with AH Plus sealer, and prepared for post cementation. Fiberglass posts were cemented using RelyX U200, and bond strength (BS) tests were conducted after 7 days and after 6 months. Failure patterns were evaluated under a stereomicroscope, while adhesive quality was analyzed through confocal laser scanning microscopy (CLSM). Proteolytic activity was assessed using in situ zymography and immunofluorescence to detect matrix metalloproteinase (MMP) −2 and −9 expression. Statistical analyses included two-way ANOVA for bond strength, three-way ANOVA for enzymatic activity and immunofluorescence, chi-square test for failure modes, and Kruskal-Wallis test with Dwass-Steel-Critchlow-Fligner post-hoc for resin cement adaptation.</div></div><div><h3>Results</h3><div>CHX and DW showed the highest BS values (10.6 ± 4.1 and 9.7 ± 5.8, respectively), while GA produced the lowest (1.9 ± 1.4). Chi-square analysis indicated more adhesive failures in the GA group at both evaluation times. CLSM revealed poor adhesive adaptation in the GA group, with noticeable gaps. Additionally, GA treatment was associated with increased proteolytic activity and presence of MMP-2 and MMP-9 at the adhesive interface.</div></div><div><h3>Conclusions</h3><div>Overall, GA resulted in lower bond strength compared to CHX and DW, inadequate adaptation at the adhesive interface adaptation, and increased MMP activity.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104126"},"PeriodicalIF":3.5,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical behavior of repaired resin composites, zirconia, and hybrid ceramics fabricated by additive and subtractive manufacturing technologies: An in vitro study","authors":"Rafat Sasany ,&nbsp;Dalndushe Abdulai ,&nbsp;Nese Ciziroğlu ,&nbsp;Seyed Ali Mosaddad ,&nbsp;Pedro Diaz","doi":"10.1016/j.ijadhadh.2025.104128","DOIUrl":"10.1016/j.ijadhadh.2025.104128","url":null,"abstract":"<div><div>The aim of this study was to evaluate the effects of substrate material and repair composite on surface wettability, shear‐bond strength (SBS), and interfacial stress distribution of direct repairs to digitally fabricated restorations. One hundred and twenty disk‐shaped specimens (Ø 10 × 2 mm) were divided into six substrate groups (n = 20): two additively manufactured resin composites (Crowntec, C; NextDent C&amp;B, ND), two printed zirconias (LithaCon 3Y‐TZP, LI; INNI‐Cera 3Y‐TZP, IN) and two subtractively manufactured ceramics (Vita Enamic PICN, EN; IPS e.max ZirCAD MT, IPZ). Each group was repaired with either a microhybrid (Clearfil Majesty Esthetic, CL) or a nanofilled composite (Filtek Z350 XT, FZ; n = 10). Contact angles were measured post-conditioning via sessile drop. Specimens were thermocycled, then SBS was evaluated at 0.5 mm/min. Two-way ANOVA with Tukey post-hoc (α = 0.05) analyzed angle and SBS. Finite element analysis of a 200 N shear load mapped interfacial stress distributions. Contact angles ranged from 58.5 ± 6.1° (IN–FZ) to 71.2 ± 7.7° (C–CL), with significant effects of substrate (<em>p</em> = 0.018), composite (<em>p</em> = 0.041), and their interaction (<em>p</em> = 0.036). SBS was highest on IN (CL: 26.9 ± 4.0 MPa; FZ: 28.5 ± 3.6 MPa) and lowest on C (15.0 ± 2.0 MPa; 15.2 ± 1.8 MPa; <em>p</em> &lt; 0.05). FZ tended toward higher SBS than CL, although within-substrate differences were non-significant. FEA revealed that FZ repairs produced more centralized tensile‐stress cores than CL repairs, and stiffer substrates (IPZ) showed higher compressive stresses. Both substrate and composite type significantly influence wettability, shear-bond strength, and interfacial stress distribution. Nanofilled composites paired with MDP‐based adhesives optimize repair performance on ceramic substrates.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104128"},"PeriodicalIF":3.5,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144887223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of adhesively bonded similar and dissimilar joints under cyclic hygrothermal aging for aerospace applications","authors":"P. Pragathi ,&nbsp;S. Jeba Jenison ,&nbsp;G. Raja Singh ,&nbsp;K. Ashoka Vijayan ,&nbsp;R. Velmurugan","doi":"10.1016/j.ijadhadh.2025.104130","DOIUrl":"10.1016/j.ijadhadh.2025.104130","url":null,"abstract":"<div><div>In this study hygrothermal exterior environment aging condition was selected to perform the aging tests for (0–28 days) on single lap joints (SLJs) of aluminum alloy-mild steel (AL-MS), (MS-MS) and (AL-AL). The change in chemical groups of the adhesive was evaluated using Fourier transform infrared spectroscopy (FTIR). The adhesive joint was evaluated by failure modes and shear strength-displacement behaviour. The microstructure of the fracture surface was examined using High-resolution scanning electron microscopy (HR-SEM). The results indicate that hygrothermal aging conditions accelerate the reduction in displacement for AL-AL joints compared to MS-MS and MS-AL joints. Additionally, the shear strength of AL-MS joints is lower than MS-MS joints but higher than the AL-AL joints. As the duration of hygrothermal aging increased, the fracture surface of the adhesive joints significantly decreased. The failure mode of unaged AL-AL joints is cohesive-adhesive, whereas the aged AL-AL joint exhibits interfacial failure initiating at the edges and propagating toward the center, resulting in a decrease in shear strength. HR-SEM analysis revealed formations of cracks and morphology changes are the effect of hygrothermal aging on the adhesive-bonded joints.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104130"},"PeriodicalIF":3.5,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144878326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrically conductive adhesives based on PMMA resin with tin-coated copper fillers for enhanced conductivity and stability","authors":"M. Najafloo ,&nbsp;R. Pourata ,&nbsp;M.H. Rasoulifard","doi":"10.1016/j.ijadhadh.2025.104127","DOIUrl":"10.1016/j.ijadhadh.2025.104127","url":null,"abstract":"<div><div>Electrically conductive adhesives (ECAs) are gaining attention as environmentally friendly and durable alternatives to traditional lead-based solders. In this study, cost-effective and oxidation-resistant tin-coated copper (Cu@Sn) powders were synthesized via an electroless plating method and employed as conductive fillers in polymethyl methacrylate (PMMA)-based ECAs. The influence of filler type and content on the electrical and mechanical properties of the ECAs was systematically investigated. Cu@Sn fillers formed conductive networks within the PMMA matrix, significantly enhancing charge transport. Notably, at an optimal filler loading of 70 wt%, the ECA exhibited a low bulk resistivity of 1.84 × 10⁻⁵ Ω m and an adhesion strength of 3.21 MPa. Thermogravimetric analysis confirmed the thermal stability of the Cu@Sn/PMMA system, indicating its suitability for high-temperature applications. These findings demonstrate that Cu@Sn-based ECAs offer a promising pathway toward high-performance, cost-efficient, and scalable lead-free interconnect solutions.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104127"},"PeriodicalIF":3.5,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144878463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of fucoxanthin on bond strengths of resin-dentin hybrid layer through matrix metalloproteinase inhibition","authors":"Won Sek Lee ,&nbsp;Yeon Kim ,&nbsp;Moon-Kyoung Bae ,&nbsp;Kyung-Hyeon Yoo ,&nbsp;Youn-Kyung Choi ,&nbsp;Yong-Il Kim","doi":"10.1016/j.ijadhadh.2025.104121","DOIUrl":"10.1016/j.ijadhadh.2025.104121","url":null,"abstract":"<div><div>Fucoxanthin has been widely studied for its anti-inflammatory, antioxidant, and anticancer properties. However, these properties have not yet been studied. This study aimed to evaluate whether pretreatment of dentin with fucoxanthin before resin restoration improved the bond stability of resin-dentin hybrid layers. Fucoxanthin primers at concentrations of 0.1, 0.5, and 1.0 wt% were applied to demineralized dentin and subjected to microtensile bond strength (MTBS) and nanoleakage tests before and after collagenase aging, followed by surface observation using scanning electron microscopy (SEM). Matrix metalloproteinase (MMP) activity was analyzed via in situ zymography, collagen cross-link formation was examined using Fourier-transform infrared spectroscopy (FTIR), and the cytotoxicity of fucoxanthin was evaluated using a cell viability assay with human dental pulp stem cells (HDPSCs). Fucoxanthin treatment improved bond strength and reduced nanoleakage compared with that of controls under both aged and non-aged conditions. SEM revealed enhanced micromechanical integration, and in situ zymography showed reduced MMP activity at higher concentrations. The FTIR spectra suggested the retention of collagen-associated structural features following fucoxanthin treatment. A dose-dependent reduction in HDPSC viability was observed at higher concentrations tested in μg/mL, which differed from the wt% used in bonding tests. These findings suggest that fucoxanthin pretreatment may improve resin–dentin interface stability, potentially by modulating MMP activity and preserving collagen integrity.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"142 ","pages":"Article 104121"},"PeriodicalIF":3.5,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144826500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}