International Journal of Advanced Chemistry最新文献_第8页

High performance liquid chromatography quality control 高效液相色谱质量控制

International Journal of Advanced Chemistry Pub Date : 2020-06-14 DOI: 10.14419/ijac.v8i1.30723

M. Mohammed El Amine, A. E. Ghanjaoui, A. Mandil, A. Ait Sidi Mou, R. Slimani

引用次数: 2

Comparative viscometric study of pure and acetylated gum Arabic using different plot methods 纯阿拉伯胶和乙酰化阿拉伯胶粘度测定方法的比较研究

International Journal of Advanced Chemistry Pub Date : 2020-06-04 DOI: 10.14419/ijac.v8i1.30526

Alhassan S.I, Sule S.Y, M. R., R. H.I, Baso A.A, Sheshe F.A, Jafar S.C

{"title":"Comparative viscometric study of pure and acetylated gum Arabic using different plot methods","authors":"Alhassan S.I, Sule S.Y, M. R., R. H.I, Baso A.A, Sheshe F.A, Jafar S.C","doi":"10.14419/ijac.v8i1.30526","DOIUrl":"https://doi.org/10.14419/ijac.v8i1.30526","url":null,"abstract":"Acetylation of gum Arabic was achieved using acetic anhydride as solvent. The ester group formed was confirmed by FTIR spectra having absorption band of 750 cm-1 – 700 cm-1. Viscometric study of the pure and acetylated samples was carried out. Relative viscosity of acetylated gum was found to be higher than that of the pure gum. Intrinsic viscosity was determined for the two samples using different plot methods taking Huggin’s plot as standard. The intrinsic viscosity was found to be 86.43 cm3/g and 64.59 cm3/g for acetylated and pure gum arabic respectively. Relative errors of other methods for the two samples was compared to that of Huggins and the plots that are most comparable to Huggins with relative errors less than 5% are; Martin, Lyon-Tobolsky, Staudinger-Heuer, Maron-Reznik and our proposed method. The proposed method which was a modification of the Kreiser method gave relative error less than 2 %, for both pure and modified gum. Whereas the Kreiser method gave relative error greater than 15 % for both methods. The critical concentration for the samples was found to be 0.0116 g/cm3 and 0.0155 g/cm3 for acetylated and pure gum respectively. This shows that there was no molecule-molecule entanglements during viscosity measurements. ","PeriodicalId":13723,"journal":{"name":"International Journal of Advanced Chemistry","volume":"105 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75825974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of ternary association of anti-microbial drug 1, 10-phenanthroline and α - amino acid with copper salt, an ultrasonic investigation of competitive interaction 抗微生物药物1,10 -菲罗啉和α -氨基酸与铜盐三元缔合的研究及竞争性相互作用的超声研究

International Journal of Advanced Chemistry Pub Date : 2020-06-04 DOI: 10.14419/ijac.v8i1.30541

Ashok Kumar Sahoo, Sunil Kumar Pradhan, Ajaya Kumar Patnaik, S. Das

{"title":"Study of ternary association of anti-microbial drug 1, 10-phenanthroline and α - amino acid with copper salt, an ultrasonic investigation of competitive interaction","authors":"Ashok Kumar Sahoo, Sunil Kumar Pradhan, Ajaya Kumar Patnaik, S. Das","doi":"10.14419/ijac.v8i1.30541","DOIUrl":"https://doi.org/10.14419/ijac.v8i1.30541","url":null,"abstract":"Molecular interaction studies using ultrasonic technique and spectroscopic investigation in ternary liquid mixture of drug 1,10-Phenanthroline, an α- amino acid Glycine and a transition metal salt like CuCl2 in aqueous medium has been carried out at 300.15K and 2 MHz frequency. Using experimental values of density (ρ),ultrasonic velocity (U) and UV analysis, different acoustical parameters such as adiabatic compressibility (β),intermolecular free length (Lf), acoustic impedance (z),relative association (RA),apparent molar volume (V∅), apparent molar adiabatic compressibility (K∅) are evaluated for the mixture of drug, glycine and inorganic salt CuCl2 at various concentrations. The ultrasonic and spectroscopic investigation clearly shows coordinative association of drug as a ligand with transition metal salt. Further interaction of glycine as an α- amino acid indicates a competitive association in the ternary system. The outcomes were expressed in terms of molecular interactions and the variation in parameters under varying solute concentrations providing conclusive remarks regarding the strength of intermolecular interactions in the ternary system with a bio-physical novelty. ","PeriodicalId":13723,"journal":{"name":"International Journal of Advanced Chemistry","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81729108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination and validation of pregabalin in bulk and pharmaceutical formulations by reversed phase-high performance liquid chromatography 反相高效液相色谱法测定原料药和制剂中普瑞巴林的含量

International Journal of Advanced Chemistry Pub Date : 2020-05-15 DOI: 10.14419/ijac.v8i1.30513

D. N. Vidya, R. Chaithra, G. P. Senthil Kumar, D. R. Bhadresh

引用次数: 0

Synthesis and characterization of pullulan derived hydrogel matrix as carrier for slow release of anti-cancer drug 普鲁兰衍生物缓释抗癌药物载体水凝胶基质的合成与表征

International Journal of Advanced Chemistry Pub Date : 2020-05-15 DOI: 10.14419/ijac.v8i1.30549

K. Bello

引用次数: 0

Validated HPTLC method for the quantitation of levetiracetam in pure and tablet dosage form 采用高效液相色谱法测定左乙拉西坦纯剂型和片剂剂型的含量

International Journal of Advanced Chemistry Pub Date : 2020-05-15 DOI: 10.14419/ijac.v8i1.30542

Likitha T G, J. Gnana Babu C., S. H G

引用次数: 0

Method development and validation of clobazam in bulk and pharmaceutical dosage forms by using high performance thin layer chromatographic method 高效薄层色谱法测定氯巴唑原料药和制剂的方法建立和验证

International Journal of Advanced Chemistry Pub Date : 2020-04-28 DOI: 10.14419/ijac.v8i1.30498

C. R., Senthil Kumar Gp, P. P, Vidya Dn, Bhadresh Dr, M. S

引用次数: 0

Hereditary immunity in cancer 癌症的遗传免疫

International Journal of Advanced Chemistry Pub Date : 2020-04-28 DOI: 10.14419/ijac.v8i1.30607

Alireza Heidari, Katrin E. Schmitt, M. Henderson, E. Besana

引用次数: 12

A chemical review on cancer immunology and immunodeficiency 肿瘤免疫学与免疫缺陷的化学进展

International Journal of Advanced Chemistry Pub Date : 2020-04-18 DOI: 10.14419/ijac.v8i1.30490

Alireza Heidari, Katrin E. Schmitt, M. Henderson, E. Besana

{"title":"A chemical review on cancer immunology and immunodeficiency","authors":"Alireza Heidari, Katrin E. Schmitt, M. Henderson, E. Besana","doi":"10.14419/ijac.v8i1.30490","DOIUrl":"https://doi.org/10.14419/ijac.v8i1.30490","url":null,"abstract":"Cancer is the most popular reason of death worldwide that many people struggle with it. Although the cancer is dangerous, but if it detects in early stages increases the chance of patient survival. The miRNAs are one of the important ways for early cancer detection that it caused to return an interesting field for researches. All the miRNAs haven’t any role in cancer detection. The Quantum Genetic Algorithm (QGA) is a developed Genetic Algorithm (GA) that by using of quantum computing on top of the genetic algorithm to alleviate the pre convergence problem. The interest of this study is to adopt the QGA for solving of informative miRNAs selection and irrelevant miRNAs removing problem. However, in the suggested algorithm, SVM classifier performance and the dimension of the selected feature vector are dependent on heuristic information for QGA. As a result, the proposed approach selects the adaptive feature subset with respect to the shortest feature dimension and the improved performance of the classifier. The performances of this method are evaluated on the popular data set which the experimental results show that since QGA-SVM is used as one of wrapper methods, as a result, its overall performance is better separation between normal and cancer expression for all types of cancer and better classification rate. ","PeriodicalId":13723,"journal":{"name":"International Journal of Advanced Chemistry","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85053827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

A comprehensive review on functional roles of cancerous immunoglobulins and potential applications in cancer immunodiagnostics and immunotherapy 癌症免疫球蛋白的功能作用及其在癌症免疫诊断和免疫治疗中的潜在应用综述

International Journal of Advanced Chemistry Pub Date : 2020-04-18 DOI: 10.14419/ijac.v8i1.30500

Alireza Heidari, Victoria Peterson

引用次数: 21