International journal of cardiology最新文献

{"title":"Serial quantitative flow ratio measurements of a successfully recanalized coronary chronic total occlusion","authors":"Mohamed Samy ,&nbsp;Abdelhakim Allali ,&nbsp;Sultan Alotaibi ,&nbsp;Ralph Toelg ,&nbsp;Volker Geist ,&nbsp;Marwa Zakaria ,&nbsp;Stephan Fichtlscherer ,&nbsp;Holger Nef ,&nbsp;Gert Richardt ,&nbsp;Nader Mankerious ,&nbsp;Karim Elbasha","doi":"10.1016/j.ijcard.2025.133897","DOIUrl":"10.1016/j.ijcard.2025.133897","url":null,"abstract":"<div><h3>Background</h3><div>Physiological assessment is useful in detecting suboptimal results after percutaneous coronary intervention (PCI). However, after angiographically successful PCI of a chronic total occlusion (CTO), coronary perfusion changes over time, which may impact physiological assessment.</div></div><div><h3>Purpose</h3><div>To evaluate the functional results of CTO PCI measured by quantitative flow ratio (QFR) immediately and 6 months following the PCI.</div></div><div><h3>Methods</h3><div>We retrospectively included patients with a successful CTO-PCI from a single center between 2017 and 2020. A total of 139 patients who fulfilled the QFR eligibility criteria, out of 470 CTO-PCIs, were enrolled. The QFR was measured off-line in the target vessel immediately post-index procedure and after a follow-up of 6 months.</div></div><div><h3>Results</h3><div>The mean age was 67.3 ± 10 years, and 80.6% were males. 74.8% of lesions had J-CTO score ≥2, retrograde approach was used in 10.8%. The median QFR immediately after successful CTO-PCI was 0.96 IQR [0.92-0.99] which increased to 0.97 IQR [0.94-0.99] after follow-up (p=0.045). Immediately post CTO-PCI, 19.4% (n=27) of patients had QFR &lt; 0.91, and 80.6% (n=112) had QFR ≥ 0.91. After 6 months, QFR increased significantly in patients with initial suboptimal QFR (0.87 IQR [0.85-0.88] vs 0.97 IQR [0.92-0.99], p&lt;0.001). Patients with persistent high QFR or those with improving QFR ≥ 0.91 at follow up had lower rates of two-year target vessel failure (HR 0.22, 95% CI: 0.09-0.54, p=0.002).</div></div><div><h3>Conclusion</h3><div>After CTO recanalization, QFR increased significantly at 6 months in most of the patients with low initial values. Patients with persistent high QFR or those with improving QFR ≥ 0.91 after a short-term follow up had lower rates of two-year TVF.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"442 ","pages":"Article 133897"},"PeriodicalIF":3.2,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to a comment re: \"Impact of diagnosis-to-ablation time (DAT) on rhythm outcomes after catheter ablation for atrial fibrillation (AF)\".","authors":"Takafumi Okuyama, Tomonori Watanabe","doi":"10.1016/j.ijcard.2025.133892","DOIUrl":"10.1016/j.ijcard.2025.133892","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":" ","pages":"133892"},"PeriodicalIF":3.2,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra-aortic balloon pump implantation in early-stage cardiogenic shock reduces 30-day mortality in patients with ventricular septal defect following myocardial infarction","authors":"Linsong Leng ,&nbsp;Xiangjuan Liu ,&nbsp;Chunfei Song ,&nbsp;Xiangzhen Ran ,&nbsp;Zongwei Lin ,&nbsp;Chungang Zhai ,&nbsp;Xiaoteng Qin ,&nbsp;Guangqing Cao ,&nbsp;Cheng Zhang ,&nbsp;Jianmin Yang","doi":"10.1016/j.ijcard.2025.133895","DOIUrl":"10.1016/j.ijcard.2025.133895","url":null,"abstract":"<div><h3>Background</h3><div>Ventricular septal defect (VSD) is a serious mechanical complication of acute myocardial infarction, with an extremely high mortality. Intra-aortic balloon pump (IABP) has become a bridge to surgical repair. However, its effect on mortality varies partly because of shock severity.</div></div><div><h3>Aims</h3><div>This study aims to evaluate the association between IABP implantation in early-stage cardiogenic shock and the 30-day all-cause mortality in patients with VSD after myocardial infarction (MI-VSD).</div></div><div><h3>Methods</h3><div>The retrospective data were collected based on MI-VSD patients who were admitted to Qilu Hospital of Shandong University from 2013 to 2024. Patients were stratified according to IABP implantation. We determined the severity of shock according to the Society for Cardiovascular Angiography and Interventions (SCAI) SHOCK stage classification system. The primary outcome was all-cause mortality within 30 days after VSD. Logistic regression models were constructed to evaluate the factors associated with the 30-day all-cause mortality. We conducted subgroup analysis and assessed interaction effects to evaluate the relationship between IABP use and 30-day mortality in various subgroups. The Kaplan-Meier curves were used to determine the cumulative incidence of 30-day mortality. We also compared the long-term outcomes of the patients.</div></div><div><h3>Results</h3><div>This study included a total of 57 patients, 33 of whom received IABP implantation. The SCAI SHOCK stage was associated with 30-day all-cause mortality. IABP implantation significantly reduced 30-day mortality in patients with SCAI SHOCK stages A/B (6.7 % versus 55.6 %; OR 0.06, 95 % CI 0.01–0.64, <em>P</em> = 0.020), while no significant difference was observed in stages C/D/E patients. We also found that IABP implantation effectively prevented progression to stages C/D/E in stages A/B patients. In addition, IABP treatment in SCAI SHOCK stages A/B significantly elevated the long-term survival rate.</div></div><div><h3>Conclusions</h3><div>Implantation of IABP in SCAI SHOCK stages A/B could reduce 30-day all-cause mortality in MI-VSD patients.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"442 ","pages":"Article 133895"},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145045677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: Diastolic dysfunction as predictive parameter for the development of post-TIPS cardiac decompensation.","authors":"Max F G H M Venner, Job A J Verdonschot, Christian Knackstedt","doi":"10.1016/j.ijcard.2025.133886","DOIUrl":"10.1016/j.ijcard.2025.133886","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":" ","pages":"133886"},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145052900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interleukin-1 blockade in patients with ST-segment elevation myocardial infarction with and without history of coronary artery disease","authors":"Rocio I. Lopez ,&nbsp;Matteo Morello ,&nbsp;Michele Golino ,&nbsp;Austin C. Hogwood ,&nbsp;Michele Marchetta ,&nbsp;Marco G. Del Buono ,&nbsp;Francesco Moroni ,&nbsp;James Mbualungu ,&nbsp;Carla R. Agatiello ,&nbsp;Benjamin W. Van Tassell ,&nbsp;Antonio Abbate","doi":"10.1016/j.ijcard.2025.133888","DOIUrl":"10.1016/j.ijcard.2025.133888","url":null,"abstract":"<div><h3>Background</h3><div>Patients with a history of coronary artery disease (CAD) presenting with ST-elevation myocardial infarction (STEMI) have high risk. We aimed to determine whether patients with CAD history presenting with STEMI had greater systemic inflammation and/or whether they benefitted similarly from IL-1 blockade.</div></div><div><h3>Methods</h3><div>We pooled data from three randomized clinical trials, including 139 patients with STEMI treated with anakinra or placebo. Patients were stratified by history of CAD defined as prior documented CAD, MI or coronary revascularization. The area under the curve (AUC) for C-reactive protein (CRP) was used to assess systemic inflammation. Event-free survival defined as the time from enrollment to the occurrence of a predefined adverse outcome, including new-onset heart failure, hospitalization for heart failure, or death, was compared using Cox regression analysis.</div></div><div><h3>Results</h3><div>Of the 139 patients, 113 (81 %) had no history of CAD, while 26 (19 %) had a history of CAD. The CRP-AUC was significantly lower in the anakinra group compared placebo, independent of history of CAD: 85 [47–137] vs. 349 [154–580] mg·day/L for anakinra and placebo, respectively, in patients with history of CAD, and 86 [43–179] vs. 213 [115–341] mg·day/L in patients without CAD history; p for interaction = (0.27). No significant interactions were found between history of CAD and treatment allocation for the composite outcome for patients with and without history of CAD, respectively, p for interaction = (0.48).</div></div><div><h3>Conclusion</h3><div>IL-1 blockade with anakinra in STEMI leads to similar reductions in systemic inflammation and improvement in HF-related outcomes inpatients both with and without history of CAD.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"442 ","pages":"Article 133888"},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145052977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to\"Exploring the role of lipid biomarkers in linking dysglicemia to subclinical atherosclerosis\" from Guo-Ming Zhang and Yanmin Song.","authors":"Bruna Gigante, Carl Johan Östgren","doi":"10.1016/j.ijcard.2025.133891","DOIUrl":"10.1016/j.ijcard.2025.133891","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":" ","pages":"133891"},"PeriodicalIF":3.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reappraising the role of MAFLD in myocardial strain: The importance of infarct burden and fibrosis phenotype.","authors":"Jinzhen Huang, Nan He, Zeming Wu","doi":"10.1016/j.ijcard.2025.133869","DOIUrl":"10.1016/j.ijcard.2025.133869","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":" ","pages":"133869"},"PeriodicalIF":3.2,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to \"Rethinking MCS metrics and regional disparities in AMI-CS\".","authors":"Hong Wang, Yuwei Liu, Xiaotong Hou","doi":"10.1016/j.ijcard.2025.133879","DOIUrl":"10.1016/j.ijcard.2025.133879","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":" ","pages":"133879"},"PeriodicalIF":3.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconsidering thyroid hormone assessment in heart failure risk prediction.","authors":"Xuesi Chen, Qijun Zhang, Yingchun Bao","doi":"10.1016/j.ijcard.2025.133872","DOIUrl":"10.1016/j.ijcard.2025.133872","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":" ","pages":"133872"},"PeriodicalIF":3.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Experience matters: Optimizing alcohol septal ablation outcomes in obstructive hypertrophic cardiomyopathy","authors":"Alfredo Mauriello ,&nbsp;Adriana Correra ,&nbsp;Vincenzo Russo ,&nbsp;Antonello D’Andrea","doi":"10.1016/j.ijcard.2025.133890","DOIUrl":"10.1016/j.ijcard.2025.133890","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"442 ","pages":"Article 133890"},"PeriodicalIF":3.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}