International journal of cardiology最新文献

{"title":"Outcomes of the Qatar Transcatheter aortic valve implantation- registry (QATAVI-registry) –first report 24/7/2024","authors":"Abdulrahman Alnabti ,&nbsp;Salem Abujalala ,&nbsp;Mohammed Al-Hijji ,&nbsp;Khaled Othman ,&nbsp;Ihsan Rafie ,&nbsp;Jassim Al Suwaidi ,&nbsp;Huseyin C. Yalcin ,&nbsp;Ruba Sulaiman ,&nbsp;Ahmed Seri ,&nbsp;Tahir Hamid","doi":"10.1016/j.ijcard.2025.133029","DOIUrl":"10.1016/j.ijcard.2025.133029","url":null,"abstract":"<div><h3>Background</h3><div>Transcatheter aortic valve implantation (TAVI) is a therapeutic modality for high-surgical-risk patients with severe aortic stenosis. This study describes the outcomes of TAVI performed in Qatar.</div></div><div><h3>Methods</h3><div>The Qatar TAVI registry (QATAVI) was established to report the outcomes of TAVI procedures performed at Hamad Medical Corporation- Heart Hospital between October 2012 and December 2023. Data were collected both prospectively and retrospectively.</div></div><div><h3>Results</h3><div>241 patients underwent TAVI, with a mean age of 73 ± 8 years. The device success rate was 98.8 %. In-hospital para-valvular leak (PVL) was as follows; mild 8.3 %, moderate 0.8 %, and severe 0.0 %. At 1-year, PVL was mild 2.9 %, moderate 0.4 %, and severe 0.0 %. At 2 years, 0.4 % had mild PVL, moderate 0.4 %, and severe 0.0 %. The incidence of stroke was 2.1 % during hospitalization, 2.1 % at 1 year, and 1.2 % at 2 years. For myocardial infarction, the in-hospital rate was 0.8 %, at 1 year 3.3 %, and 1.2 % at 2 years. 3.7 % developed heart failure during the hospital stay, 15.4 % at 1 year, and 4.6 % at 2 years. The 30-day mortality rate was 2.0 %, while a 1-year survival rate was 91 %. Among the 1-year mortality, 67 % died from non-cardiovascular causes.</div></div><div><h3>Conclusion</h3><div>The inaugural report of QATAVI demonstrates a success rate that matches international standards, favorable early and late valvular functions, and improved clinical outcomes related to major adverse cardiovascular events. Moreover, the survival rates observed in this cohort align with those reported in global registries, demonstrating the safety and effectiveness of the TAVI procedure in Qatar.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"424 ","pages":"Article 133029"},"PeriodicalIF":3.2,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leaflet tethering in mitral transcatheter edge-to-edge repair: No longer a barrier","authors":"Tetsu Tanaka","doi":"10.1016/j.ijcard.2025.133025","DOIUrl":"10.1016/j.ijcard.2025.133025","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"423 ","pages":"Article 133025"},"PeriodicalIF":3.2,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left atrial strain: A newly emerging prognostic marker for ST-elevation myocardial infarction.","authors":"Shi Fang Mo, Qing Ping Zeng, Li Yang","doi":"10.1016/j.ijcard.2025.133034","DOIUrl":"https://doi.org/10.1016/j.ijcard.2025.133034","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":" ","pages":"133034"},"PeriodicalIF":3.2,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clarifying the crossroads of autonomy, authority, and adherence","authors":"Alina Yang","doi":"10.1016/j.ijcard.2025.133035","DOIUrl":"10.1016/j.ijcard.2025.133035","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"423 ","pages":"Article 133035"},"PeriodicalIF":3.2,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The particular anatomy of atrioventricular septal defect with a common valvar orifice in patients with Down syndrome: an echocardiographic study","authors":"Zahra Belhadjer ,&nbsp;Margaux Pontailler ,&nbsp;Manon Hily ,&nbsp;Régis Gaudin ,&nbsp;Olivier Raisky ,&nbsp;Damien Bonnet ,&nbsp;Lucile Houyel","doi":"10.1016/j.ijcard.2025.133003","DOIUrl":"10.1016/j.ijcard.2025.133003","url":null,"abstract":"<div><h3>Objectives</h3><div>Atrioventricular septal defect with a common valvar orifice is associated with Down syndrome in almost half of cases. Clinical studies have shown that associated tetralogy of Fallot is more frequent in Down patients. The aim of this study was to compare the anatomy of the ventricles and of the ventricular component of the atrioventricular septal defect, looking for an outlet septum malalignment like in tetralogy of Fallot, in patients with and without Down syndrome.</div></div><div><h3>Methods</h3><div>We reviewed retrospectively the echocardiographic examinations of all consecutive patients hospitalized with atrioventricular septal defect with a common orifice between 01/01/2016 and 01/09/2023. Anatomic and functional characteristics were compared between Down and non-Down patients.</div></div><div><h3>Results</h3><div>A total of 310 patients were included (Down syndrome 210, 67.7 %). Outlet extension of the ventricular component of the defect with outlet septum anterior malalignment was found in 90.6 % of Down vs 12.8 % of non-Down patients (<em>p</em> &lt; 0.001). Hypoplasia and apical filling of the right ventricle were more frequent in Down patients (p &lt; 0.001). Associated tetralogy of Fallot was found in 16 Down vs 1 non-Down patients (<em>p</em> = 0.04). Atrioventricular septal malalignment was observed only in Down patients.</div></div><div><h3>Conclusion</h3><div>Outlet extension of the ventricular component of the defect is the rule in atrioventricular septal defect with a common orifice in Down patients, which could influence surgical repair. Hypoplastic right ventricle occurs only in Down patients. The presence of these characteristics in a fetus with atrioventricular septal defect with a common orifice should raise awareness of the high risk of associated Down syndrome.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"423 ","pages":"Article 133003"},"PeriodicalIF":3.2,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of rate-adaptive pacing on patients with chronotropic incompetence: Systematic review and meta-analysis of randomized controlled trials","authors":"Shunsuke Kuroda ,&nbsp;Iwanari Kawamura ,&nbsp;Yuki Sahashi ,&nbsp;Reina Tonegawa-Kuji ,&nbsp;Toshiki Kuno","doi":"10.1016/j.ijcard.2025.133022","DOIUrl":"10.1016/j.ijcard.2025.133022","url":null,"abstract":"<div><h3>Background</h3><div>Rate-adaptive pacing (RAP) complements heart rate (HR) responses in patients with cardiac pacing devices and chronotropic incompetence, although improvements in exercise capacity have varied across reported studies. The purpose of this study was to evaluate the effectiveness of the RAP mode across different clinical settings.</div></div><div><h3>Methods</h3><div>A systematic review and meta-analysis were conducted according to PRISMA guidelines. MEDLINE and EMBASE databases were searched through May 2024. Randomized controlled trials comparing RAP-on with RAP-off modes in patients with chronotropic incompetence were included. Outcomes related to exercise capacity, such as peak oxygen uptake (VO2), exercise duration, and patient-reported outcomes (PROs), were analyzed.</div></div><div><h3>Results</h3><div>Twelve trials with a total of 1199 patients were included. The meta-analysis showed that RAP-on significantly improved peak VO2 (mean difference [MD]: 1.35 ml/kg/min, 95 % confidence interval [CI]: 0.47 to 2.23) and exercise duration (MD:0.74 min, 95 % CI: 0.14 to 1.33) with augmenting peak HR (MD: 19 bpm, 95 % CI: 13 to 26) during cardiopulmonary exercise tests. The effectiveness of RAP on exercise capacity blunted particularly in patients with heart failure (HF) (MD: 0.36 ml/kg/min, 95 % CI: −0.88 to 1.60) compared with those without HF (MD: 1.95 ml/kg/min, 95 % CI: 0.66 to 3.23). PROs showed no significant improvement with RAP-on except for one study including non-HF.</div></div><div><h3>Conclusions</h3><div>RAP-on mode significantly enhances exercise capacity in patients with chronotropic incompetence, however, the benefits are less pronounced in patients with concomitant HF. In patient with HF, careful assessment is crucial to identify potential need for advanced therapeutic approach following the RAP-on pacing.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"423 ","pages":"Article 133022"},"PeriodicalIF":3.2,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The emerging roles of cardiac sympathetic innervation in arrhythmogenic cardiomyopathy","authors":"Tania Zaglia ,&nbsp;Marco Mongillo","doi":"10.1016/j.ijcard.2025.133006","DOIUrl":"10.1016/j.ijcard.2025.133006","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"423 ","pages":"Article 133006"},"PeriodicalIF":3.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eligibility for and practical implications of Semaglutide in overweight and obese patients with acute coronary syndrome","authors":"Vincenzo De Sio ,&nbsp;Felice Gragnano ,&nbsp;Antonio Capolongo ,&nbsp;Natale Guarnaccia ,&nbsp;Pasquale Maddaluna ,&nbsp;Vincenzo Acerbo ,&nbsp;Mattia Galli ,&nbsp;Martina Berteotti ,&nbsp;Simona Sperlongano ,&nbsp;Arturo Cesaro ,&nbsp;Elisabetta Moscarella ,&nbsp;Francesco Pelliccia ,&nbsp;Giuseppe Patti ,&nbsp;Emilia Antonucci ,&nbsp;Plinio Cirillo ,&nbsp;Pasquale Pignatelli ,&nbsp;Gualtiero Palareti ,&nbsp;Vittorio Pengo ,&nbsp;Paolo Gresele ,&nbsp;Rossella Marcucci ,&nbsp;Paolo Calabrò","doi":"10.1016/j.ijcard.2025.133028","DOIUrl":"10.1016/j.ijcard.2025.133028","url":null,"abstract":"<div><h3>Aims</h3><div>Semaglutide has been shown to reduce cardiovascular events in non-diabetic patients with preexisting cardiovascular disease and overweight/obesity in the SELECT trial. Data on the applicability of these results to clinical practice are limited. We evaluated the eligibility for and practical implications of semaglutide in overweight/obese non-diabetic patients with recent acute coronary syndrome (ACS) from a contemporary real-world registry.</div></div><div><h3>Methods</h3><div>Patients from the multicenter START-ANTIPLATELET registry (<span><span>NCT02219984</span><svg><path></path></svg></span>) were stratified to investigate the proportion of patients eligible for semaglutide &gt;60 days after discharge for ACS (post-acute phase), according to the SELECT trial eligibility criteria: age ≥ 45 years; body mass index ≥27 kg/m²; history of myocardial infarction (MI), stroke, or peripheral artery disease; no diabetes. Major adverse cardiovascular events (MACE), defined as a composite of all-cause death, MI, target vessel revascularization, or stroke, and net adverse clinical events (NACE), a composite of all-cause death, MI, stroke, or major bleeding, were assessed at 1-year follow-up.</div></div><div><h3>Results</h3><div>The study population comprised 2940 consecutive ACS patients. At 60 days after discharge, 807 patients (27.4 %) met the SELECT eligibility criteria (SELECT-like group) and 2133 patients were ineligible (not-eligible group). At 1 year, incidence of MACE (4.6 % vs. 8.2 %; <em>p</em> = 0.004) and NACE (3.6 % vs. 7.6 %; <em>p</em> &lt; 0.001) was lower in the SELECT-like group compared to the not-eligible group.</div></div><div><h3>Conclusions</h3><div>In a contemporary real-world registry, a significant proportion of post-ACS patients were eligible for semaglutide according to the SELECT trial criteria. Future studies are needed to evaluate the potential implications of semaglutide for secondary prevention.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"423 ","pages":"Article 133028"},"PeriodicalIF":3.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of left atrial strain for left ventricular reverse remodeling in dilated cardiomyopathy","authors":"Qimin Fang ,&nbsp;Ao Kan ,&nbsp;Shuhao Li ,&nbsp;Yaohan Yu ,&nbsp;Jiankun Dai ,&nbsp;Yipei Song ,&nbsp;Xiwen Wang ,&nbsp;Xuan Xiao ,&nbsp;Lin Xu ,&nbsp;Lianggeng Gong","doi":"10.1016/j.ijcard.2025.133020","DOIUrl":"10.1016/j.ijcard.2025.133020","url":null,"abstract":"<div><h3>Background</h3><div>Early prediction of left ventricular reverse remodeling (LVRR) can guide the subsequent treatment in dilated cardiomyopathy (DCM) patients. We aimed to investigate the value of left atrium (LA) strain for predicting LVRR in DCM patients.</div></div><div><h3>Methods</h3><div>Clinical and imaging data of DCM patients were gather between January 2018 and January 2023. The participators were divided into LVRR group and non-LVRR group according to the ultrasound follow-up results. CMR images were process to yield LA fast long-axis strain parameters. Univariate and multivariate logistic regression analysis was used to screen the predictors and establish the prediction model.</div></div><div><h3>Results</h3><div>The study included 116 participants. LVRR occurred in 69 participants within 1 year. Compared with the non-LVRR group, the LVRR group has smaller left ventricular end-diastolic volume index (LVEDVi), late gadolinium enhancement extent (LGE%) and higher left atrial passive eject fraction (LAPEF), left atrial reservoir strain (LARS) and left atrial conduit strain (LACS). In multivariable logistic regression analysis, LVEDVi (HR: 0.990; 95 % CI: 0.981, 0.999; <em>P</em> = 0.037), LACS (HR: 1.434; 95 % CI: 1.025, 2.007; <em>P</em> = 0.035) and LGE% (HR: 0.713; 95 % CI: 0.584, 0.870; <em>P</em> = 0.001) were independent predictors of LVRR. The model based on NYHA, LVEDVi, LGE% and LACS had a better performance in predicting LVRR (AUC = 0.807; 95 % CI: 0.723; 0.874).</div></div><div><h3>Conclusions</h3><div>LVEDVi, LACS and LGE% were independent predictors of LVRR within 1 year in DCM patients. The combination of NYHA, LVEDVi, LACS and LGE% has a better predictive performance.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"423 ","pages":"Article 133020"},"PeriodicalIF":3.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrence of atrial fibrillation: Low dose colchicine and allopurinol","authors":"Ertan Yetkin","doi":"10.1016/j.ijcard.2025.133013","DOIUrl":"10.1016/j.ijcard.2025.133013","url":null,"abstract":"","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":"423 ","pages":"Article 133013"},"PeriodicalIF":3.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}