International journal of cardiology最新文献

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Transcaval access for transcatheter aortic valve implantation: A meta-analysis and systematic review 经腔镜主动脉瓣植入术:荟萃分析和系统综述。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-12 DOI: 10.1016/j.ijcard.2024.132720
Bishoy Abraham , Mina Sous , Sara Kaldas , Michael Nakhla , John Sweeney , Kwan Lee , Santiago Garcia , Marwan Saad , Sachin S. Goel , F. David Fortuin
{"title":"Transcaval access for transcatheter aortic valve implantation: A meta-analysis and systematic review","authors":"Bishoy Abraham ,&nbsp;Mina Sous ,&nbsp;Sara Kaldas ,&nbsp;Michael Nakhla ,&nbsp;John Sweeney ,&nbsp;Kwan Lee ,&nbsp;Santiago Garcia ,&nbsp;Marwan Saad ,&nbsp;Sachin S. Goel ,&nbsp;F. David Fortuin","doi":"10.1016/j.ijcard.2024.132720","DOIUrl":"10.1016/j.ijcard.2024.132720","url":null,"abstract":"<div><h3>Background</h3><div>Anatomical factors may preclude transfemoral (TF) arterial access for transcatheter aortic valve implantation (TAVI). Transcaval (TCav) access has been utilized as an alternative access for these patients. We aimed to investigate the outcomes of TCav access in patients undergoing TAVI.</div></div><div><h3>Methods</h3><div>We performed a systematic review and meta-analysis including all published studies from 1996 to November 2023 that examined TCav access in patients undergoing TAVI. The main outcomes included all cause mortality, major vascular complications, major bleeding, stroke, and myocardial infarction (MI). Outcomes were reported at 30-day and 1-year follow-up.</div></div><div><h3>Results</h3><div>We included 8 observational studies with a total of 517 patients (mean age 78.1±8 years, 56.6 % women, mean STS score 7 ± 4.5). Mean (SD) procedure time was 35 ± 9.8 mins and mean (SD) contrast volume was 136.3 ± 77.4 ml. Procedure success was achieved in 94.3 % of the patients. At 30-day follow-up, all-cause mortality occurred in 6.4 %, major bleeding in 12.2 %, blood transfusion in 23.3 %, retroperitoneal bleeding in 19 %, major vascular complications in 7.9 %, MI in 2.8 %, and AKI in 6.4 % of patients. At 1-year, all-cause mortality was 14.7 %. In a sub-group analysis including 3 studies comparing TCav (<em>n</em> = 316) to alternative accesses (including transcarotid, transaxillary, and transapical) (<em>n</em> = 303), there were no differences in all-cause mortality, major bleeding, major vascular complications, blood transfusion, or stroke at 30-day.</div></div><div><h3>Conclusion</h3><div>Transcaval approach is feasible and non-inferior to other alternative accesses in TAVI patients with prohibitive iliofemoral anatomy.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preclinical evaluation of the sirolimus-eluting iron bioresorbable scaffold in canine below-the-knee artery. 西罗莫司洗脱铁生物可吸收支架在犬膝下动脉中的临床前评估。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-11 DOI: 10.1016/j.ijcard.2024.132722
Guoyi Sun, Wanqian Zhang, Tao Li, Gui Zhang, Haifeng Li, Xian Gao, Guoxian Zhu, Deyuan Zhang, Wei Guo
{"title":"Preclinical evaluation of the sirolimus-eluting iron bioresorbable scaffold in canine below-the-knee artery.","authors":"Guoyi Sun, Wanqian Zhang, Tao Li, Gui Zhang, Haifeng Li, Xian Gao, Guoxian Zhu, Deyuan Zhang, Wei Guo","doi":"10.1016/j.ijcard.2024.132722","DOIUrl":"https://doi.org/10.1016/j.ijcard.2024.132722","url":null,"abstract":"<p><strong>Background and aims: </strong>Infrapopliteal artery intervention has yielded suboptimal results in below-the-knee (BTK) arterial disease. However, bioresorbable scaffolds are a potential treatment for this condition. This study compared the support performance, anti-hyperplastic effects, and histological manifestations between a sirolimus-eluting iron bioresorbable scaffold (IBS) and an everolimus-eluting stent (EES) within 6 months and the corrosion profile during 12 months in canine BTK arteries.</p><p><strong>Methods: </strong>Eighteen IBS and twelve EES systems were implanted into nonatherosclerotic BTK arteries in dogs. Support performance and inhibit intimal hyperplasia, histological manifestations, and the corrosion profile were compared between the two systems using angiography, optical coherence tomography (OCT), micro-computed tomography, and histopathologic evaluation at 1, 3, 6, and 12 months.</p><p><strong>Results: </strong>All systems were successfully implanted. There was no significant difference in the area of stenosis between the IBS and EES groups within 6 months. Semi-quantitative OCT revealed degradation of the IBS at 3 months, with strut corrosion rates of 24.6 %, 45.0 %, and 69.2 % at 3, 6, and 12 months. Micro-computed tomography showed that the IBS maintained its integrity at 1 month without corrosion, with more struts fractured because of degradation at 6 and 12 months. Endothelialization was complete at 1 month in both groups. There was no significant between-group difference in cell responses during 6 months of follow-up, with the exception of macrophages.</p><p><strong>Conclusion: </strong>This preclinical study suggests that the IBS has performance support, anti-hyperplastic effects, and histological manifestations comparable to those of the EES within 6 months, with a reasonable corrosion profile over 12 months.</p>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deferral of left main coronary artery revascularization via IVUS or coronary physiology - Long-term outcomes from the SWEDEHEART registry. 通过 IVUS 或冠状动脉生理学推迟左冠状动脉主干再通术 - SWEDEHEART 登记的长期结果。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-11 DOI: 10.1016/j.ijcard.2024.132726
Karolina Berntorp, Moman A Mohammad, Sasha Koul, Troels Yndigegn, Sofia Bergman, Sammy Zwackman, Rikard Linder, Sebastian Völz, Ole Fröbert, David Erlinge, Matthias Götberg
{"title":"Deferral of left main coronary artery revascularization via IVUS or coronary physiology - Long-term outcomes from the SWEDEHEART registry.","authors":"Karolina Berntorp, Moman A Mohammad, Sasha Koul, Troels Yndigegn, Sofia Bergman, Sammy Zwackman, Rikard Linder, Sebastian Völz, Ole Fröbert, David Erlinge, Matthias Götberg","doi":"10.1016/j.ijcard.2024.132726","DOIUrl":"https://doi.org/10.1016/j.ijcard.2024.132726","url":null,"abstract":"<p><strong>Background: </strong>Intravascular ultrasound (IVUS) guides deferral decision-making regarding the left main coronary artery (LMCA) and improves outcomes. Further studies regarding coronary physiology to guide revascularization in the LMCA are needed. Our aim was to evaluate the outcome of LMCA deferral using IVUS or coronary physiology via instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR).</p><p><strong>Methods: </strong>Between January 2014 and February 2022, patients undergoing evaluation with either IVUS or coronary physiology in the LMCA were included from the SWEDEHEART registry. Exclusion criteria were a minimum luminal area < 6 mm<sup>2</sup>, iFR ≤ 0.89, FFR ≤ 0.80, ad hoc percutaneous coronary intervention of lesions in the LMCA, proximal left anterior descending artery, and proximal circumflex artery, planned elective revascularization, and planned valvular surgery. The primary outcome was major adverse cardiac events (MACE), defined as a composite of all-cause death, myocardial infarction, and unplanned revascularization. Kaplan-Meier event rates and multivariable Poisson regression were used for the statistical analyses.</p><p><strong>Results: </strong>Deferral of revascularization in the LMCA was performed in 1552 patients, 33.6 % with IVUS and 66.4 % with coronary physiology (iFR 11.3 % vs. FFR 55.0 %). The median follow-up time was 2.7 years. No significant difference was seen in MACE (IVUS 40.2 % vs. coronary physiology 35.5 %; adjusted RR: 1.18; 95 %CI: 0.97-1.44; p = 0.09). The results were consistent across all investigated subgroups. The rate of all-cause death was higher in the IVUS group (adjusted RR: 1.38; 95 %CI: 1.03-1.83; p = 0.03).</p><p><strong>Conclusions: </strong>Deferral of coronary revascularization in LMCA lesions using IVUS or coronary physiology did not differ in our combined endpoint. We observed a higher risk of all-cause death using IVUS.</p>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac magnetic resonance in patients with Takotsubo syndrome: Clinical correlates of T2 mapping Takotsubo 综合征患者的心脏磁共振:T2 映射的临床相关性。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-10 DOI: 10.1016/j.ijcard.2024.132716
Luca Arcari , Giovanni Camastra , Federica Ciolina , Emanuela Belmonte , Domenico De Santis , Massimiliano Danti , Damiano Caruso , Viviana Maestrini , Francesco Santoro , Natale Daniele Brunetti , Andrea Laghi , Stefano Sbarbati , Luca Cacciotti
{"title":"Cardiac magnetic resonance in patients with Takotsubo syndrome: Clinical correlates of T2 mapping","authors":"Luca Arcari ,&nbsp;Giovanni Camastra ,&nbsp;Federica Ciolina ,&nbsp;Emanuela Belmonte ,&nbsp;Domenico De Santis ,&nbsp;Massimiliano Danti ,&nbsp;Damiano Caruso ,&nbsp;Viviana Maestrini ,&nbsp;Francesco Santoro ,&nbsp;Natale Daniele Brunetti ,&nbsp;Andrea Laghi ,&nbsp;Stefano Sbarbati ,&nbsp;Luca Cacciotti","doi":"10.1016/j.ijcard.2024.132716","DOIUrl":"10.1016/j.ijcard.2024.132716","url":null,"abstract":"<div><h3>Background</h3><div>Extensive myocardial edema is a key feature of acute takotsubo syndrome (TTS) and it can be quantitatively assessed by T2 mapping cardiac magnetic resonance (CMR) imaging. Clinical correlates of myocardial edema in TTS are not well characterized.</div></div><div><h3>Methods</h3><div>Sixty patients with acute TTS underwent CMR with T2 mapping within one week of hospitalization. Disease severity was assessed by a validated risk score (GEIST-score).</div></div><div><h3>Results</h3><div>Mean age of the study population was 71 ± 12 years (92 % females). Mean mid-septal T2 time was 58 ± 6 ms. Higher T2 mapping values were found in patients with left ventricular ejection fraction (LVEF) ≤40 % (60 ± 6 ms vs 56 ± 5 ms; <em>p</em> = 0.006), male sex (66 ± 7 ms vs 58 ± 6 ms; <em>p</em> = 0.010), dyspnea on admission (63 ± 7 ms vs 58 ± 6 ms; p = 0.006), absence of an emotional trigger (60 ± 7 ms vs 57 ± 5 ms; <em>p</em> = 0.039), intermediate-to-severe GEIST-score (63 ± 7 ms vs 58 ± 6 ms; <em>p</em> = 0.045) and in-hospital complications (61 ± 1 ms vs 58 ± 6 ms; <em>p</em> = 0.009). A trend towards higher values was observed in patients who died at follow-up (62 ± 8 ms vs 58 ± 6 ms; <em>p</em> = 0.098). On linear regression analysis, T2 mapping did not correlate with the timing of CMR (Beta −0.182, <em>p</em> = 0.170), whereas after multivariable correction, lack of emotional trigger (Beta 0.262, <em>p</em> = 0.031), decreasing LVEF (Beta −0.254, <em>p</em> = 0.024) and increasing GEIST score (Beta 0.282, p = 0.024) remained independently associated with T2 mapping.</div></div><div><h3>Conclusions</h3><div>In patients with acute TTS undergoing a timely CMR within the first week after admission, T2 mapping was not affected by timing of the examination, was higher in patients displaying high-risk features, and independently associated with the GEIST risk score.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized comparison of rapid versus oximetry guided deflation of the transradial-band after coronary angiography or angioplasty 冠状动脉造影术或血管成形术后经桡动脉带快速放气与血氧饱和度引导放气的随机比较。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-10 DOI: 10.1016/j.ijcard.2024.132708
Christel Gry Aagren Nielsen , Martin Bøhme Rasmussen , Pernille Thordahl Rhode , Dorte Vitt Bagner , Rebekka Vibjerg Jensen , Lars Jakobsen , Nicolaj Brejnholt Støttrup , Karsten Tange Veien , Ellen Nyholm Larsen , Mette Gitz Charlot , Anne Elisabeth Boesgaard , Christian Juhl Terkelsen
{"title":"Randomized comparison of rapid versus oximetry guided deflation of the transradial-band after coronary angiography or angioplasty","authors":"Christel Gry Aagren Nielsen ,&nbsp;Martin Bøhme Rasmussen ,&nbsp;Pernille Thordahl Rhode ,&nbsp;Dorte Vitt Bagner ,&nbsp;Rebekka Vibjerg Jensen ,&nbsp;Lars Jakobsen ,&nbsp;Nicolaj Brejnholt Støttrup ,&nbsp;Karsten Tange Veien ,&nbsp;Ellen Nyholm Larsen ,&nbsp;Mette Gitz Charlot ,&nbsp;Anne Elisabeth Boesgaard ,&nbsp;Christian Juhl Terkelsen","doi":"10.1016/j.ijcard.2024.132708","DOIUrl":"10.1016/j.ijcard.2024.132708","url":null,"abstract":"<div><h3>Background</h3><div>Transradial access is recommended for coronary angiography and angioplasty, and is associated with fewer complications when compared to femoral access. Nevertheless, there is a risk of hematoma and radial artery occlusion (RAO), and substantial time may elapse until hemostasis is achieved.</div></div><div><h3>Aims</h3><div>We aimed to evaluate if an oximetry-guided deflation technique compared to a traditional rapid deflation technique was associated with earlier removal of the transradial band (TR-band) and lower rates of RAO following radial coronary intervention.</div></div><div><h3>Methods</h3><div>Between October 2018 and December 2021, we randomized 3600 patients to either traditional rapid deflation where 1/3 of volume in the TR-band was removed every 20 min and reinflated if bleeding, or oximetry-guided deflation aiming at patent hemostasis and full deflation of the TR-band after 60 min, with cross-over to traditional deflation if bleeding at the time of deflation.</div></div><div><h3>Results</h3><div>A TR-band was applied in 3540 patients, and data on time to removal was available in 3288 (93 %) of these. The time to full deflation of the TR-band was 92 versus 74 min, <em>P</em> &lt; 0.01 and the time to removal of the TR-band was 112 versus 100 min, P &lt; 0.01 in patients randomized to traditional rapid (<em>n</em> = 1767) versus oximetry-guided deflation (<em>n</em> = 1773). The rate of RAO or sub- occlusion evaluated by oximetry after TR-band removal was 1.2 % versus 1.8 %, <em>P</em> = 0.16.</div></div><div><h3>Conclusion</h3><div>Traditional rapid deflation of the TR-band with the first deflation attempt after 20 min is associated with re-bleeding and prolonged time to removal of the TR-band, as compared to a strategy where the first deflation attempt is performed after 60 min. Oximetry-guided deflation, however, was not associated with lower rates of RAO or subocclusion.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic utility of dynamic changes in epicardial adipose tissue in patients undergoing transcatheter aortic valve replacement 经导管主动脉瓣置换术患者心外膜脂肪组织动态变化的预后作用。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-10 DOI: 10.1016/j.ijcard.2024.132697
Shuangxiang Lin , Yao Zhang , Shuyue Wang , Xingfa Ding , Jiaxing Wu , Xinhong Wang , Jianzhong Sun
{"title":"Prognostic utility of dynamic changes in epicardial adipose tissue in patients undergoing transcatheter aortic valve replacement","authors":"Shuangxiang Lin ,&nbsp;Yao Zhang ,&nbsp;Shuyue Wang ,&nbsp;Xingfa Ding ,&nbsp;Jiaxing Wu ,&nbsp;Xinhong Wang ,&nbsp;Jianzhong Sun","doi":"10.1016/j.ijcard.2024.132697","DOIUrl":"10.1016/j.ijcard.2024.132697","url":null,"abstract":"<div><h3>Background</h3><div>Epicardial Adipose Tissue (EAT) volume is associated with the risk of cardiovascular events, which can be assessed by cardiac computed tomography. However, he optimal method and their prognostic utility in patients following transcatheter aortic valve replacement (TAVR) is unknown.</div></div><div><h3>Methods</h3><div>We evaluated 258 participants, focusing on changes in EAT volume using cardiac CT enhancement. EAT volume was automatically computed as three-dimensional voxels between −190 to −30 HU on contrast-enhanced slices. Univariate and multivariable Cox regression analyses were conducted to assess the association of various clinical parameters and EAT volume indices with major adverse cardiovascular events (MACE).</div></div><div><h3>Results</h3><div>During a median follow-up of 2.0 years [IQR, 1.8–2.3 years], 34 participants (median age 73 [IQR: −13.1 to −8.3) years, 55.4 % male) experiencing MACE. The optimal cutoff values for EAT volume change fraction (EATVCF) was 15.2 %, determined by the Youden-index. Kaplan-Meier curve analysis revealed that patients with high EATVCF were at higher risk (<em>p</em> &lt; .01). In Cox regression, EATVCF (hazard ratio [HR]: 0.92, 95 % CI: 0.87 to 0.97, <em>p</em> = .001) remained significantly associated with MACE after adjusting for clinical factors. The addition of EATVCF to the clinical model increased the net Reclassification Improvement (NRI) by 30.1 % (95 % CI: 0.07–1.16).</div></div><div><h3>Conclusion</h3><div>EAT volume change fraction emerged as a significant predictor of MACE post-TAVR, highlighting the clinical value of EAT volume assessment in cardiovascular risk stratification.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review. 循环生物标志物对预测先天性心脏病患者不良心脏事件的临床影响。系统综述。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-10 DOI: 10.1016/j.ijcard.2024.132723
W J van Genuchten, H Averesch, Q M van Dieren, D Bonnet, M Odemarsky, M Beghetti, J W Roos-Hesselink, Z Reinhardt, C Male, E Naumburg, E Boersma, D De Wolf, W A Helbing
{"title":"Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.","authors":"W J van Genuchten, H Averesch, Q M van Dieren, D Bonnet, M Odemarsky, M Beghetti, J W Roos-Hesselink, Z Reinhardt, C Male, E Naumburg, E Boersma, D De Wolf, W A Helbing","doi":"10.1016/j.ijcard.2024.132723","DOIUrl":"https://doi.org/10.1016/j.ijcard.2024.132723","url":null,"abstract":"<p><strong>Introduction: </strong>Patients with congenital heart disease (ConHD) are at increased risk for adverse cardiac events. Predicting long-term outcomes and guidance of patient management might benefit from a range of (new) biomarkers. This is a rapidly evolving field with potentially large consequences for clinical decision making. With a systematic review of available biomarkers in ConHD we identified the clinical role of these markers, knowledge gaps and future research directions.</p><p><strong>Methods: </strong>We systematically reviewed the literature on associations between blood biomarkers and outcome measures (mortality or composite adverse outcomes in patients with ConHD.</p><p><strong>Results: </strong>The inclusion criteria were met by 102 articles. Biomarkers assessed in more than studies are discussed in the main text, those studied in 3 or less studies are summarized in the supplement. Thus, we discuss 15 biomarkers from 92 studies. These biomarkers were studied in 32,399 / 10,735 patients for the association with mortality and composite adverse outcomes, respectively. Biomarkers that were studied most and had statistically significant associations with mortality or composite adverse outcomes were (NT-pro)BNP, MELD-XI score, Hs-CRP, creatinine, albumin and sodium. Most of these biomarkers are involved in intracardiac processes associated with inflammation or are markers of renal function.</p><p><strong>Conclusion: </strong>For (NT-pro)BNP, clinical value for prediction of mortality and composite adverse outcomes in adult and paediatric ConHD has been shown. For MELD-XI, hs-CRP, albumin, creatinine, sodium, RDW, and GDF-15, correlations with mortality and composite adverse outcomes have been demonstrated in patient groups with mixed types of ConHD, but clinical utility needs additional exploration.</p>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bundle branch block patterns during atrial fibrillation rhythm for heart failure events 心衰事件心房颤动节律期间的束支传导阻滞模式。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-09 DOI: 10.1016/j.ijcard.2024.132710
Tetsuma Kawaji , Yasuhiro Hamatani , Masashi Kato , Takafumi Yokomatsu , Shinji Miki , Mitsuru Abe , Masaharu Akao , on behalf of the Fushimi AF Registry investigators
{"title":"Bundle branch block patterns during atrial fibrillation rhythm for heart failure events","authors":"Tetsuma Kawaji ,&nbsp;Yasuhiro Hamatani ,&nbsp;Masashi Kato ,&nbsp;Takafumi Yokomatsu ,&nbsp;Shinji Miki ,&nbsp;Mitsuru Abe ,&nbsp;Masaharu Akao ,&nbsp;on behalf of the Fushimi AF Registry investigators","doi":"10.1016/j.ijcard.2024.132710","DOIUrl":"10.1016/j.ijcard.2024.132710","url":null,"abstract":"<div><h3>Aims</h3><div>The clinical significance of bundle branch block (BBB) during atrial fibrillation (AF) rhythm in relation to heart failure (HF) events remains to be elucidated. This study aimed to explore the associations between BBB patterns and HF in AF patients.</div></div><div><h3>Methods and results</h3><div>We enrolled 2721 AF patients whose baseline electrocardiography during AF rhythm was available from a community-based prospective survey, the Fushimi AF Registry. Associations between complete left or right BBB (CLBBB/CRBBB) and the composite HF endpoint (a composite of hospitalization due to HF or cardiac death) were examined. CLBBB and CRBBB were observed in 31 patients (1.2%) and 218 patients (8.2%), respectively. Patients with BBB were older, and had a higher prevalence of chronic kidney disease, pre-existing HF, and lower left ventricular function than those without BBB. During a median follow-up period of 6.0 (2.2–9.0) years, the incidence of the primary composite HF endpoint was significantly higher in patients with CLBBB and CRBBB than those without BBB (CLBBB: 10.2% versus 3.5% per patient-year, log-rank <em>P</em> &lt; 0.001; CRBBB: 6.5% versus 3.5% per patient-year, log-rank P &lt; 0.001). In multivariable analysis, both CLBBB and CRBBB were independent predictors of the primary composite HF endpoint (adjusted hazard ratio 1.83 and 1.46, respectively).</div></div><div><h3>Conclusions</h3><div>CRBBB as well as CLBBB during AF rhythm were associated with higher risk of HF events in AF patients.</div></div>","PeriodicalId":13710,"journal":{"name":"International journal of cardiology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GP73 promotes the ox-LDL-induced inflammation in macrophages by activating the ERK/AKT pathway GP73 通过激活 ERK/AKT 通路促进氧化-LDL 诱导的巨噬细胞炎症。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-09 DOI: 10.1016/j.ijcard.2024.132718
Xian Liu , Yu-Ping Wang , Shao-Yang Sun , Lin Zhu , Kun Ren
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引用次数: 0
Why the Athlete's heart matters: Insights into Arrhythmogenic cardiomyopathy 运动员的心脏为何重要?了解心律失常性心肌病。
IF 3.2 2区 医学
International journal of cardiology Pub Date : 2024-11-08 DOI: 10.1016/j.ijcard.2024.132699
Liliana Szabo , Hajnalka Vago
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引用次数: 0
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