Integrative zoology最新文献_第7页

Host Trait–Based Patterns of Parasite Species Co-occurrence in Component Communities: A Case Study With Fleas Parasitic on Small Mammals 基于寄主性状的组成群落寄生虫共生模式——以小型哺乳动物寄生蚤为例

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-14 Epub Date: 2025-04-11 DOI: 10.1111/1749-4877.12981

Boris R. Krasnov, Georgy I. Shenbrot, Irina S. Khokhlova

{"title":"Host Trait–Based Patterns of Parasite Species Co-occurrence in Component Communities: A Case Study With Fleas Parasitic on Small Mammals","authors":"Boris R. Krasnov, Georgy I. Shenbrot, Irina S. Khokhlova","doi":"10.1111/1749-4877.12981","DOIUrl":"10.1111/1749-4877.12981","url":null,"abstract":"<div>\u0000 \u0000 We applied a novel eigenvector ellipsoid method to investigate patterns of flea species co-occurrences on small mammalian hosts from six biogeographic realms. We asked whether the application of this method that links host trait–associated requirements of flea species (represented by eigenvector ellipsoids based on the traits of hosts exploited by them) with their among-host distribution would allow us to detect the same patterns as those identified by traditional methods for detecting non-randomness in species co-occurrences. We also asked whether (a) congeneric and heterogeneric species pairs differ in their pairwise pattern of co-occurrence and (b) the patterns of flea species co-occurrences in regional compound communities are associated with the regions’ environmental characteristics. Although flea species seem to be randomly associated in the majority of communities, the values of average ellipsoid overlap suggested different degrees of species aggregation rather than segregation. Clear patterns of nestedness and modularity, in among-host flea distribution, were detected in a few communities only. Congeneric species pairs showed higher ellipsoid overlap and longer distances between their centroids than heterogeneric pairs. The relationship between the overlap of host-associated flea niches in a region and regional precipitation was either positive or negative, depending on the realm. The results of the application of the eigenvector ellipsoid method appeared to be more reliable than those produced by traditional methods, which overestimated the degree of species aggregation and underestimated differences in co-occurrence patterns between conspecific and heterogeneric species pairs.\u0000 </div>","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":"21 5","pages":"1158-1172"},"PeriodicalIF":3.7,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RNA Virus Diversity, Cross-Species Transmission, and Molecular Constraints in Two Closely Related Rat Species RNA病毒多样性、跨种传播和两种亲缘关系密切的大鼠的分子限制。

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-14 Epub Date: 2026-04-25 DOI: 10.1111/1749-4877.70104

Zhiming Li, Mingyu Zhang, Ruidong Cao, Chengmin Shi, Le Yang, Jianxu Zhang, Yaohua Zhang

{"title":"RNA Virus Diversity, Cross-Species Transmission, and Molecular Constraints in Two Closely Related Rat Species","authors":"Zhiming Li, Mingyu Zhang, Ruidong Cao, Chengmin Shi, Le Yang, Jianxu Zhang, Yaohua Zhang","doi":"10.1111/1749-4877.70104","DOIUrl":"10.1111/1749-4877.70104","url":null,"abstract":"<div>\u0000 \u0000 Viral infection involves co-evolution with hosts, yet the molecular determinants that constrain viral cross-species transmission remain poorly understood. Here, we established conspecific and heterospecific co-housing models for two closely related rat species, Rattus norvegicus (RN) and Rattus tanezumi (RT), both maintained in laboratory settings for over 10 generations, together with wild-caught RT individuals. Using meta-transcriptomic sequencing and population genomic analyses, we compared their RNA virus profiles and investigated the potential molecular constraints on cross-species viral transmission. From 63 rats, we characterized an extensive RNA virome comprising more than 600 viruses, including 7 zoonotic viruses, 29 viruses with cross-species transmission potential, and 335 novel viruses. Notably, the prevalence of Seoul orthohantavirus (SEOV) was significantly higher in RN than in RT. Population genomic analysis revealed that RN exhibited higher heterozygosity in Itgb3 (the gene encoding the SEOV receptor, β3-integrin) and Tlr7 (the gene encoding the receptor for viral ssRNA, Toll-like receptor 7) compared to RT. These genetic variations likely represent the molecular determinants responsible for the differential susceptibility to SEOV between the two species. Our findings clarify the diversity and prevalence of RNA viruses in closely related rodent species and highlight host genetic barriers that may influence zoonotic spillover risk.\u0000 </div>","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":"21 5","pages":"1145-1157"},"PeriodicalIF":3.7,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Melanocortin 1 Receptor Signaling Protects Against Tubular Epithelial Cell Injury and M1 Macrophage Polarization in Acute Kidney Injury 黑素皮质素1受体信号传导对急性肾损伤小管上皮细胞损伤和M1巨噬细胞极化的保护作用

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-14 Epub Date: 2026-04-22 DOI: 10.1111/1749-4877.70113

Zhan Chen, Wenqing Chen, Yong Liu, Shaokang Pan, Jiayu Duan, Dongwei Liu, Jiancheng Dong, Zhangsuo Liu, Yingjin Qiao

{"title":"Melanocortin 1 Receptor Signaling Protects Against Tubular Epithelial Cell Injury and M1 Macrophage Polarization in Acute Kidney Injury","authors":"Zhan Chen, Wenqing Chen, Yong Liu, Shaokang Pan, Jiayu Duan, Dongwei Liu, Jiancheng Dong, Zhangsuo Liu, Yingjin Qiao","doi":"10.1111/1749-4877.70113","DOIUrl":"10.1111/1749-4877.70113","url":null,"abstract":"<div>\u0000 \u0000 Acute kidney injury (AKI) is characterized by high incidence and mortality rates, and a lack of specific targeted therapies. Inflammatory responses mediated by immune cells and direct damage to renal tubular epithelial cells underlie AKI development. Melanocortin exerts renoprotective effects through systemic immune regulation; however, the renoprotective role of melanocortin 1 receptor (MC1R) remains unclear. MC1R-deficient (e/e) mice developed higher serum creatinine levels, more severe renal dysfunction, and greater histological damage than wild-type (WT) mice following folic acid-induced AKI. Treatment with MC1R agonist MS05 improved experimental nephritis in WT mice; however, this effect was less pronounced in e/e mice. The exacerbation of AKI in e/e mice was associated with damage to renal tubular epithelial cells and macrophage infiltration, where MC1R is highly expressed. MC1R alleviates tubular cell inflammation by inhibiting the nuclear factor-κB pathway and suppresses the polarization of M1 macrophages. Chimeric mice were generated through transplantation of bone marrow-derived macrophages after irradiation. Macrophages from e/e mice with MC1R dysfunction exacerbated kidney injury in WT mice, whereas those from WT mice mitigated kidney injury in e/e mice. Targeting MC1R in renal tubular epithelial cells and macrophages provides a novel treatment concept for AKI.\u0000 </div>","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":"21 5","pages":"1173-1189"},"PeriodicalIF":3.7,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Echolocators Are Smaller Than Their Non-Echolocating Relatives: Agility Counts in Dark, Three-Dimensional Habitats 回声定位器比非回声定位器更小：在黑暗的三维栖息地中，敏捷性很重要。

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-14 Epub Date: 2026-01-12 DOI: 10.1111/1749-4877.70052

Jinyu Guo, Jie Wang, Chris Newman, Juncheng Li, Hanyu Xiang, Christina D. Buesching, David W. Macdonald, Youbing Zhou, Nan Wu

{"title":"Echolocators Are Smaller Than Their Non-Echolocating Relatives: Agility Counts in Dark, Three-Dimensional Habitats","authors":"Jinyu Guo, Jie Wang, Chris Newman, Juncheng Li, Hanyu Xiang, Christina D. Buesching, David W. Macdonald, Youbing Zhou, Nan Wu","doi":"10.1111/1749-4877.70052","DOIUrl":"10.1111/1749-4877.70052","url":null,"abstract":"<div>\u0000 \u0000 Evolutionary and behavioral adaptations are frequently linked to animal sensory perception. Echolocators have evolved instantaneous and highly adaptive control over their sensory and motor actions enabling them to detect and capture rapidly moving, evasive prey in three-dimensional space. Specifically, among volant bats, maneuverability decreases with increasing mass, while toothed whales and dolphins have evolved tight turning rates and radii to enable them to capture small and elusive fish. We thus hypothesize that selection pressures should have driven the evolution of relatively smaller body size among echolocators to enhance their agility. To test this, we conducted PGLS and GLMM model analyses comparing the body mass of 1327 echolocating species with 4878 non-echolocating species. In support of our body size filtering hypothesis, echolocating species tended to be significantly smaller than their non-echolocating relatives across the entire body mass range, both generally and at the order and family levels. Furthermore, our findings transcended the concurrent effects of habitat type and dietary preferences on modulating body size distributions, as well as ecogeographical rules relating to the evolution of body size. This shows that the echolocator–body size relationship has evolved independently across vertebrate taxa that diverged millions of years ago. Nevertheless, the resultant diversity of extant, relatively small echolocating species and the key functional roles they play in ecosystems may be vulnerable to contemporary anthropogenic disturbances.\u0000 </div>","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":"21 5","pages":"1254-1265"},"PeriodicalIF":3.7,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145951778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparisons Between Large-Scale Genomic Variants and SNPs in Driving Population Divergence and Local Adaptation. 大规模基因组变异和snp在驱动种群分化和局部适应中的比较。

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-09 DOI: 10.1111/1749-4877.70183

Qianghui Zhu, Hongrui Lv, Yalin Cheng, Shangyu Wang, Dezhi Zhang, Yan Hao, Gang Song, Fumin Lei

{"title":"Comparisons Between Large-Scale Genomic Variants and SNPs in Driving Population Divergence and Local Adaptation.","authors":"Qianghui Zhu, Hongrui Lv, Yalin Cheng, Shangyu Wang, Dezhi Zhang, Yan Hao, Gang Song, Fumin Lei","doi":"10.1111/1749-4877.70183","DOIUrl":"https://doi.org/10.1111/1749-4877.70183","url":null,"abstract":"Genomic variations, such as indels (2-49 bp) and structural variants (SVs, ≥50 bp), are larger-scale mutations than single nucleotide polymorphisms (SNPs) and can substantially impact evolutionary processes, including speciation, adaptation, and phenotypes. Despite their functional importance, integrative population genetic analyses that jointly consider genome-wide SNPs, indels, and SVs remain under-explored. The ground tit (Pseudopodoces humilis), an endemic species to the Qinghai-Tibet Plateau (QTP), exhibits divergence across distinct glacial refugia, accompanied by habitat and morphological divergence, making it an excellent example for investigating how different types of genomic variants contribute to population divergence and local adaptation. Here, by retrieving 81 whole-genome sequence data, over 13 million SNPs, 2 million indels, and 22,101 SVs were identified. Variants were unevenly distributed across the genome, characterized by distinct hotspot regions. Indels and SVs revealed four genetic clusters consistent with previous SNP-based results, thereby validating the reliability of our variant datasets. FST and genotype-environment association (GEA) analyses independently revealed numerous candidate indels and SVs; each showed minimal overlap with previously identified SNPs, and were enriched in similar functional pathways such as signal transduction, skeletal muscle development, water transport, DNA repair, reproduction, nervous system development, and immunity. Collectively, our results demonstrated that indels and SVs could capture additional signatures besides SNPs. Furthermore, similar but distinct gene functions among different types of genomic variants collectively and complementarily drive genomic divergence across environmental gradients in such a high-elevation endemic species, underscoring its evolutionary relevance in local adaptation.","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148911622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Matrine-Tea Saponin Synergism Involves Suppressed Detoxification and Digestion in a Leaf Beetle. 苦参-茶皂素协同作用涉及抑制叶甲虫的解毒和消化。

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-09 DOI: 10.1111/1749-4877.70203

Owais Khan, Xiayu Li, Yanping Zhang, Runhua Han, Letian Xu

{"title":"Matrine-Tea Saponin Synergism Involves Suppressed Detoxification and Digestion in a Leaf Beetle.","authors":"Owais Khan, Xiayu Li, Yanping Zhang, Runhua Han, Letian Xu","doi":"10.1111/1749-4877.70203","DOIUrl":"10.1111/1749-4877.70203","url":null,"abstract":"Botanical pesticide mixtures offer a sustainable strategy to enhance insecticidal activity and mitigate resistance. The leaf beetle Plagiodera versicolora, a destructive defoliator in forests and urban ecosystems, poses a growing management challenge. This study investigates the individual toxicity, synergistic effects, and underlying molecular mechanisms of two representative botanical agents, matrine and tea saponin, against P. versicolora. Bioassays revealed strong individual toxicity, with 6-day LC50 values of 1.948 µg/L for matrine and 5.589 mg/L for tea saponin. Notably, their binary mixture exhibited synergism (AI = 0.27), reducing the lethal concentrations required compared to individual treatments. Transcriptomic analysis revealed that this synergy was associated with coordinated suppression of key metabolic processes. Genes downregulated under combined exposure were enriched in detoxification-related genes (GSTs and CYP450s) and genes encoding digestive enzymes, including trypsins, chitinases, and lipases, suggesting impaired detoxification and digestive capacity. RNA interference further showed that silencing the trypsin-encoding gene Pver105950 or the chitinase-encoding gene Pver001190 significantly increased susceptibility to tea saponin or matrine, respectively, with Pver001190 knockdown producing survival comparable to that under the combined treatment. In conclusion, the synergistic toxicity of matrine and tea saponin is associated with impaired larval digestion and putative gut barrier dysfunction, together with transcriptional suppression of detoxification pathways in P. versicolora. The identification of Pver105950 and Pver001190 as critical molecular targets provides a theoretical foundation for developing high-efficiency botanical formulations for the environmentally friendly control of this pest.","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148911765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reproductive Biology, Mating System, and Extended Natal Association in the Echolocating Dalou Mountains Tree Mouse (Typhlomys daloushanensis): Insights Into Sensory Adaptation and Life-History Strategy. 回声定位的大娄山树鼠（Typhlomys daloushanensis）的生殖生物学、交配系统和扩展的出生关联：感觉适应和生活史策略的见解。

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-04 DOI: 10.1111/1749-4877.70188

Juncheng Li, Tianyu Ren, Tian Tian, Chris Newman, Rui Yuan, Nan Wu, Christina D Buesching, Youbing Zhou, Jinwei Wu

{"title":"Reproductive Biology, Mating System, and Extended Natal Association in the Echolocating Dalou Mountains Tree Mouse (Typhlomys daloushanensis): Insights Into Sensory Adaptation and Life-History Strategy.","authors":"Juncheng Li, Tianyu Ren, Tian Tian, Chris Newman, Rui Yuan, Nan Wu, Christina D Buesching, Youbing Zhou, Jinwei Wu","doi":"10.1111/1749-4877.70188","DOIUrl":"https://doi.org/10.1111/1749-4877.70188","url":null,"abstract":"Understanding mating systems is central to ecology and evolution because reproduction shapes population dynamics, social organization, and species persistence. Interpreting these processes is especially important in rodents because of the key ecological role they play in seed dispersal and terrestrial food webs. The reproductive biology of the blind, echolocating rodent Typhlomys daloushanensis is currently not known, yet this knowledge would provide a unique opportunity to link sensory biology with life history and social organization. Here, we characterize reproduction, neonatal development, and social structure for this species under laboratory conditions. We established a captive breeding colony of T. daloushanensis and quantified key reproductive parameters, including gestation length, litter size, inter-birth interval, and offspring development to puberty. Successful reproduction occurred exclusively in male-female pairs, with no mating behavior observed in group housing. The species exhibited a life history consistent with other small rodents, with gestation lasting 28-30 days, weaning at ∼21-28 days, and maturation at >60 days, contrasting with the slower reproductive schedules of echolocating bats. Litter size ranged from 2 to 5, and offspring remained with parents well beyond weaning, indicating prolonged natal association. These findings link reproduction to social organization in this species. More broadly, our results establish foundational knowledge of reproduction in this echolocating rodent and provide a basis for future work on sensory ecology, social behavior, and the development of Typhlomys as a tractable experimental system.","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrated Multi-Omics Analysis Reveals the Genetic Basis of Phenotypic Variation in Tibetan Sheep. 综合多组学分析揭示藏羊表型变异的遗传基础。

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-04 DOI: 10.1111/1749-4877.70179

Dehui Liu, Xue Li, Fei Tian, Xuexia Li, Wenxia Li, Buying Han, Ming Jiang, Yanlan Liu, Xiliu Hu, Xue Xiang, Wulong Ma, Guangcai Bao, Rong Li, Guoxiang Bao, Sijia Liu, Kai Zhao, Dehong Tian

{"title":"Integrated Multi-Omics Analysis Reveals the Genetic Basis of Phenotypic Variation in Tibetan Sheep.","authors":"Dehui Liu, Xue Li, Fei Tian, Xuexia Li, Wenxia Li, Buying Han, Ming Jiang, Yanlan Liu, Xiliu Hu, Xue Xiang, Wulong Ma, Guangcai Bao, Rong Li, Guoxiang Bao, Sijia Liu, Kai Zhao, Dehong Tian","doi":"10.1111/1749-4877.70179","DOIUrl":"https://doi.org/10.1111/1749-4877.70179","url":null,"abstract":"Body size is a key economic trait influencing the profitability of farmed animals. This study used genome-wide association studies (GWAS) to identify five single nucleotide polymorphisms (SNPs) significantly associated with body size in the Tibetan sheep population, advancing molecular breeding and providing a basis for genomic selection. These SNPs are located within five candidate genes. SNaPshot validated GWAS results, demonstrating significant correlations between candidate SNPs and body size traits in Tibetan sheep. Concurrently, hematoxylin and eosin staining, alongside muscle fiber analysis, confirmed pronounced morphological differences in muscle tissue between sheep of varying conformation. Therefore, transcriptome and proteomics were performed on the longest dorsi muscle from large and small Tibetan sheep of both sexes. The transcriptome, together with weighted gene co-expression network analysis (WGCNA), identified VEPH1 and PRKG1 as core genes regulating body characteristics in Tibetan sheep through their involvement in the PI3K-Akt signaling pathway and pathways related to fat deposition. The integrative analyses demonstrated significantly different expression of CARNS1 and CRYAB at both transcriptional and protein levels between the muscles of large- and small-sized Tibetan sheep of both sexes, suggesting their importance in body size traits by influencing muscle morphology. This study provides valuable genomic resources that advance sheep genetics research.","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gut Microbiota Analysis and Comparison in Forest Musk Deer (Moschus berezovskii) of Different Ages and Musk-Secreting Periods. 不同年龄和不同麝香分泌期森林麝肠道菌群分析与比较

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-04 DOI: 10.1111/1749-4877.70181

Jiuyan Jiang, Qiuping Huang, Fei Wu, Pingwei Liang, Linping Fan, Xia Zhou, Chengli Zheng, Xin Shi, Huina Song, Ji Wang, Jing Xue Luo, Ji Chen, Qinlin Yang, Siqi Peng, Lingqian Yin, Dejun Zeng, Hang Jie, Guangxiang Zhu

{"title":"Gut Microbiota Analysis and Comparison in Forest Musk Deer (Moschus berezovskii) of Different Ages and Musk-Secreting Periods.","authors":"Jiuyan Jiang, Qiuping Huang, Fei Wu, Pingwei Liang, Linping Fan, Xia Zhou, Chengli Zheng, Xin Shi, Huina Song, Ji Wang, Jing Xue Luo, Ji Chen, Qinlin Yang, Siqi Peng, Lingqian Yin, Dejun Zeng, Hang Jie, Guangxiang Zhu","doi":"10.1111/1749-4877.70181","DOIUrl":"10.1111/1749-4877.70181","url":null,"abstract":"Under homeostatic conditions, the gut microbiota are closely associated with host health, undergoing co-evolution with the host through complex interactions to maintain mutually beneficial symbiosis. However, dynamic changes in the gut microbiota of forest musk deer (Moschus berezovskii; FMD) at different age stages and musk-secreting periods remain unclear. In this study, we analyzed the fecal microbiota of FMD using metagenomic sequencing across four age groups (subadult, young adult, adult, and old) and four musk-secreting period groups (before musk-secreting period, during musk-secreting period, after musk-secreting period, and musk collection). The results showed that the gut microbiota structure of FMD demonstrated stability across different age stages and musk-secreting periods and was dominated by Firmicutes. Moreover, changes in musk-secreting periods had a greater effect on the gut microbiota of subadult and old FMD, while age-associated differences in gut microbial composition were mainly evident during AMSP. LDA effect size (LEfSe) and STAMP analyses further revealed significant age-associated and musk-secreting period-associated differences in the structure and function of the gut microbiota in FMD. In addition, subadult FMD showed enhanced immune response-associated and potential pathogen-associated functions during musk collection, accompanied by the enrichment of potential opportunistic pathogenic bacteria, suggesting that musk collection may be associated with host stress responses and gut microecological disturbance. In summary, this study explored the relationships among age stages, musk-secreting periods, and gut microbiota of FMD, providing a certain strategic reference for the healthy captive breeding of FMD and the improvement of musk production.","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can Food Acquisition Priority Alter Emotion, Physiological Responses, and Social Rank in Fish? 食物获取优先性能否改变鱼的情绪、生理反应和社会等级？

IF 3.7 1区生物学

Integrative zoology Pub Date : 2026-09-03 DOI: 10.1111/1749-4877.70176

Dongxing Tan, Wen Wang, Shijian Fu, Cheng Fu

{"title":"Can Food Acquisition Priority Alter Emotion, Physiological Responses, and Social Rank in Fish?","authors":"Dongxing Tan, Wen Wang, Shijian Fu, Cheng Fu","doi":"10.1111/1749-4877.70176","DOIUrl":"https://doi.org/10.1111/1749-4877.70176","url":null,"abstract":"Whether non-human animals can perceive and respond to inequitable resource distribution has become a prominent topic in behavioral and cognitive sciences. Fish possess notable cognitive capacities and display physiological and behavioral indicators of \"emotion-like states\" under stress, pain, or adverse conditions. However, it remains unclear whether fish can perceive inequitable resource allocation and exhibit emotion-related physiological and behavioral responses. Here, we investigated this question in a group-living cichlid, Chindongo demasoni, by manipulating the feeding order to create inequity in food acquisition order (priority-fed vs. delayed-fed). We examined whether this manipulation could elicit emotion-like states and whether these states were associated with variation in growth, hormone levels (dopamine and cortisol), metabolism (standard and routine metabolic rates), personality traits (activity, sociability, and aggression), and anxiety-like behaviors, ultimately influencing social hierarchy. Relative to delayed-fed individuals, priority-fed individuals consumed more food and exhibited a higher condition factor, and showed lower whole-body cortisol levels. However, no significant differences were detected between the two groups in personality traits, anxiety-like behaviors, metabolic rates, dopamine levels, or social rank. These findings suggest that Demasoni cichlids may perceive inequity in food distribution, with differences in food intake and cortisol levels consistent with emotion-like states. However, because cortisol levels and feeding/nutritional state can influence each other, the extent to which these differences reflect emotional processes versus nutritional effects remains unclear. This study provides new evidence for understanding whether and how non-human animals perceive social inequity and highlights the importance of minimizing persistent feeding-order differences in laboratory and aquaculture welfare management.","PeriodicalId":13654,"journal":{"name":"Integrative zoology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0