Insights into Imaging最新文献

筛选
英文 中文
Cost-effectiveness of contrast-enhanced breast MRI in suspicious mammographic microcalcifications. 对比增强乳房MRI在可疑乳房微钙化中的成本-效果。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-06-12 DOI: 10.1186/s13244-025-01990-y
Barbara J Fueger, Fabian Tollens, Clemens G N Kaiser, Thomas H Helbich, Nina Pötsch, Paola Clauser, Pascal A T Baltzer
{"title":"Cost-effectiveness of contrast-enhanced breast MRI in suspicious mammographic microcalcifications.","authors":"Barbara J Fueger, Fabian Tollens, Clemens G N Kaiser, Thomas H Helbich, Nina Pötsch, Paola Clauser, Pascal A T Baltzer","doi":"10.1186/s13244-025-01990-y","DOIUrl":"10.1186/s13244-025-01990-y","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the cost-effectiveness of supplemental breast magnetic resonance imaging (MRI) in women with BI-RADS 4 mammographic microcalcifications in order to avoid unnecessary stereotactic biopsies.</p><p><strong>Methods: </strong>Decision analysis and Markov modeling were used to compare the short-term costs and effects of two diagnostic strategies: supplemental breast MRI in women with mammographic microcalcifications to avoid needle biopsies in MRI negative cases vs stereotactic biopsies of all BI-RADS 4 microcalcifications.</p><p><strong>Results: </strong>Applying supplemental breast MRI resulted in comparable costs and outcomes. Average cumulative costs of US$ 56,918 and 2.932 quality adjusted life years (QALYs) per woman were achieved for the supplemental breast MRI-strategy, whereas stereotactic biopsies as standard of care resulted in cumulative costs of US$ 56,898 and 2.930 QALYs, resulting in an incremental cost effectiveness ratio (ICER) of US$ 10,047 per QALY gained.</p><p><strong>Conclusion: </strong>Due to comparable diagnostic safety at similar costs, the non-invasive breast MRI alternative for workup of mammographically detected suspicious calcifications should be offered to patients within the context of shared decision making.</p><p><strong>Critical relevance statement: </strong>Contrast-enhanced MRI of the breast should be offered as an alternative to stereotactic biopsy within the context of shared decision-making.</p><p><strong>Key points: </strong>Breast MRI and stereotactic biopsy enable accurate risk stratification of suspicious calcifications. Breast MRI and stereotactic biopsy yield comparable cost-effectiveness and clinical outcomes. Breast MRI should be considered as an option regarding shared clinical decision-making.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"122"},"PeriodicalIF":4.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Added value of multifrequency magnetic resonance elastography in predicting pathological grading of pancreatic neuroendocrine neoplasms. 多频磁共振弹性成像预测胰腺神经内分泌肿瘤病理分级的附加价值。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-06-12 DOI: 10.1186/s13244-025-02008-3
Jiaxin Yuan, Jiawei Liu, Tingting Wen, Liqin Wang, Zhenpeng Peng, Ning Zhang, Shi-Ting Feng, Jinhui Yu, Siya Shi, Yanji Luo
{"title":"Added value of multifrequency magnetic resonance elastography in predicting pathological grading of pancreatic neuroendocrine neoplasms.","authors":"Jiaxin Yuan, Jiawei Liu, Tingting Wen, Liqin Wang, Zhenpeng Peng, Ning Zhang, Shi-Ting Feng, Jinhui Yu, Siya Shi, Yanji Luo","doi":"10.1186/s13244-025-02008-3","DOIUrl":"10.1186/s13244-025-02008-3","url":null,"abstract":"<p><strong>Objectives: </strong>To prospectively investigate the pancreatic stiffness (c) and fluidity (φ) of pancreatic neuroendocrine neoplasms (pNENs), measured using multifrequency magnetic resonance elastography (MRE), and evaluate their performance in predicting pNENs pathological grade.</p><p><strong>Materials and methods: </strong>This study included 96 untreated patients with pathologically confirmed pNENs who underwent multifrequency MRE within 2 weeks before surgery between September 2021 and November 2023. Independent predictors of pathological grade were identified using multivariate regression analysis, and predictive performance was assessed using receiver operating characteristic curves.</p><p><strong>Results: </strong>The study included 76 patients with low-grade pNENs (45 men; mean age: 48.7 ± 14.0 years; Grade 1: 34 patients, Grade 2: 42 patients) and 20 patients with high-grade pNENs (10 men; mean age: 54.4 ± 13.8 years; Grade 3: 15 patients, neuroendocrine carcinoma: 5 patients). The two radiologists showed substantial or near-perfect interobserver agreement in evaluating the quantitative parameters. The multivariate regression analysis identified c and relative enhancement in the portal venous phase (V) as independent predictors of pathological grade. The combined model (V + c) had the best predictive performance (area under the curve (AUC) = 0.930; sensitivity: 95.0%; specificity: 82.9%) and outperformed V (AUC = 0.806, p = 0.010), c (AUC = 0.847, p = 0.021), and φ (AUC = 0.709, p = 0.003) alone, as well as other clinical and conventional MRI parameters (all p < 0.05) in Delong's test.</p><p><strong>Conclusions: </strong>Tumour stiffness quantified via multifrequency MRE improved the predictive performance for the pathological grade of pNENs when combined with conventional MRI parameters.</p><p><strong>Critical relevance statement: </strong>Tumour stiffness quantified using multifrequency magnetic resonance elastography provides a non-invasive, preoperative method for predicting the pathological grade of pancreatic neuroendocrine neoplasms. Predictive performance improves when combined with conventional MRI parameters, facilitating clinical decision-making and prognostic prediction.</p><p><strong>Key points: </strong>Multifrequency magnetic resonance elastography (MRE) can indicate stiffness and fluidity of pancreatic neuroendocrine neoplasms (pNENs). Tumour stiffness combined with conventional MRI parameters can independently predict pNENs pathological grade. Multifrequency MRE can serve as a biomarker for the prediction of pNENs pathological grade.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"119"},"PeriodicalIF":4.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Problem-based learning in radiology achieves similar results in classroom and metaverse settings. 放射学中基于问题的学习在课堂和虚拟环境中取得了类似的结果。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-06-12 DOI: 10.1186/s13244-025-01987-7
Teodoro Rudolphi-Solero, Fernando Bajos-Ariza, Rocío Lorenzo-Álvarez, Dolores Domínguez-Pinos, Miguel José Ruiz-Gómez, Francisco Sendra-Portero
{"title":"Problem-based learning in radiology achieves similar results in classroom and metaverse settings.","authors":"Teodoro Rudolphi-Solero, Fernando Bajos-Ariza, Rocío Lorenzo-Álvarez, Dolores Domínguez-Pinos, Miguel José Ruiz-Gómez, Francisco Sendra-Portero","doi":"10.1186/s13244-025-01987-7","DOIUrl":"10.1186/s13244-025-01987-7","url":null,"abstract":"<p><strong>Objectives: </strong>The metaverse (MV) is a simulated virtual world enabling simultaneous interaction and communication between students, teachers, and colleagues. This study compared a problem-based learning experience in radiology conducted face-to-face in real life (RL) and within the MV.</p><p><strong>Methods: </strong>During a radiology clinical rotation, groups of approximately 25 sixth-year medical students participated over 2 years in real life and 2 years in the MV. Each group was divided into eight teams of 3-4 students, each assigned a radiological clinical case for study, presentation, and debate with classmates. Students evaluated other teams, assessed case difficulty, and completed a perception questionnaire.</p><p><strong>Results: </strong>A total of 348 students participated in the real-life group and 342 in the MV group, with average teacher evaluation scores of 8.11 ± 1.15 and 7.97 ± 1.54, respectively, showing no significant differences (p = 0.883). No significant differences were found in peer evaluations or case difficulty assessments. Both groups reported positive experiences, with overall satisfaction scores out of 10 points being 7.91 ± 1.32 for RL and 7.54 ± 1.87 for the MV, without significant differences (p = 0.073).</p><p><strong>Conclusions: </strong>Problem-based learning activities in radiology can be effectively conducted in the MV, yielding academic results and experiential perceptions comparable to RL. The MV presents a viable alternative to face-to-face learning when in-person problem-based learning activities are impractical or challenging.</p><p><strong>Critical relevance statement: </strong>This study highlights the potential of the metaverse for effectively conducting radiology problem-based learning activities. It provides evidence for its viability as an alternative educational tool, particularly when face-to-face learning is not feasible.</p><p><strong>Key points: </strong>Radiology problem-based learning in the metaverse achieved academic results comparable to traditional real-life classroom settings. The metaverse offers unique learning advantages, including remote access, 24/7 availability, and teamwork opportunities. The metaverse provides an excellent problem-based learning alternative when in-person activities are impractical or impossible.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"121"},"PeriodicalIF":4.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Entrustable professional activities in Finnish radiology training: a national survey. 芬兰放射学培训中可信赖的专业活动:一项全国性调查。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-06-05 DOI: 10.1186/s13244-025-01992-w
Jussi Hirvonen, Suvi Marjasuo, Sanna Huhtaniska, Mervi Tiihonen, Milja Holstila
{"title":"Entrustable professional activities in Finnish radiology training: a national survey.","authors":"Jussi Hirvonen, Suvi Marjasuo, Sanna Huhtaniska, Mervi Tiihonen, Milja Holstila","doi":"10.1186/s13244-025-01992-w","DOIUrl":"10.1186/s13244-025-01992-w","url":null,"abstract":"<p><strong>Objectives: </strong>This study assessed the practical implementation, experiences, and attitudes toward entrustable professional activities (EPAs) in radiology training across Finland.</p><p><strong>Methods: </strong>A nationwide, anonymous online survey targeted radiology residents, recently graduated specialists (within 3 years), and instructor specialists. Distributed to all Finnish hospitals involved in radiology training, the survey evaluated EPA completion rates, perceived value, and future development needs. Responses were analyzed to identify trends and differences across groups.</p><p><strong>Results: </strong>Of 150 respondents (42% residents, 43% instructors, and 14% recent graduates), 65% were from university hospitals. Among residents and recent graduates, 37% had completed EPA assessments, with 87% valuing the feedback received and 73% finding EPAs effective for competency assessment. Overall, 64% considered EPAs well-suited to radiology. Residents showed higher completion rates (43%) than recent graduates (19%), with fourth- and fifth-year residents more engaged (69% vs. 15%). Instructors, while supportive (67% viewed EPAs as meaningful), emphasized a need for more training (54% vs. 49% of residents).</p><p><strong>Conclusion: </strong>Most Finnish radiology respondents considered EPAs well-suited for training. Residents and recent graduates who completed EPAs greatly valued the feedback and found them effective for assessing competencies, with residents participating more actively than recent graduates. Instructors' desire for better guidance suggests a priority for enhanced support and education. These findings endorse EPA integration and inform refinements in national and European radiology curricula.</p><p><strong>Critical relevance statement: </strong>Finnish radiologists and residents strongly support EPAs in radiology training, valuing their feedback and competency assessment, though instructors seek enhanced guidance.</p><p><strong>Key points: </strong>Finnish radiology residents and specialists reported positive experiences and strong support for entrustable professional activity (EPAs). Finland's mandatory, nationally coordinated EPA framework contrasts with subspecialty-focused models elsewhere. Instructors seek more EPA training, signaling a need for enhanced education to sustain their engagement as adoption grows.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"118"},"PeriodicalIF":4.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12141187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impaired right atrial function preceding right ventricular systolic dysfunction: clinical utility and long-term prognostic value in pulmonary hypertension. 右心房功能受损前右心室收缩功能障碍:肺动脉高压的临床应用和长期预后价值。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-06-04 DOI: 10.1186/s13244-025-01996-6
Fan Yang, Yan Yan, Wang Jiang, Zhouming Wang, Caixin Wu, Qian Wu, Yuanlin Deng, Yamin Du, Zhenwen Yang, Zhang Zhang, Dong Li
{"title":"Impaired right atrial function preceding right ventricular systolic dysfunction: clinical utility and long-term prognostic value in pulmonary hypertension.","authors":"Fan Yang, Yan Yan, Wang Jiang, Zhouming Wang, Caixin Wu, Qian Wu, Yuanlin Deng, Yamin Du, Zhenwen Yang, Zhang Zhang, Dong Li","doi":"10.1186/s13244-025-01996-6","DOIUrl":"10.1186/s13244-025-01996-6","url":null,"abstract":"<p><strong>Objectives: </strong>Pulmonary hypertension (PH) in patients with right ventricular systolic dysfunction (RVSD) is associated with a poor prognosis. This study assessed the characteristics of right atrial (RA) function using cardiac magnetic resonance feature tracking (CMR-FT) before RVSD onset and evaluated the long-term prognostic significance of these characteristics.</p><p><strong>Materials and methods: </strong>A total of 96 PH patients, including 36 without RVSD (PH-nonRVSD) and 60 with RVSD (PH-RVSD), were compared to 20 healthy controls (HCs). The RA reservoir, conduit, booster pump functions, and the right ventricular global longitudinal strain (RVGLS) were evaluated. Ventricular morphological and functional parameters of the RA and right ventricle (RV) were also acquired.</p><p><strong>Results: </strong>Compared with HCs, both RA reservoir and conduit functions were significantly reduced (p<sub>s</sub> < 0.05) in the PH-nonRVSD, without significant morphological changes in either the RA or RV (p<sub>s</sub> > 0.05). The RA reservoir and conduit function were significantly correlated with the right ventricular ejection fraction (RVEF), RVGLS, pulmonary vascular resistance, brain natriuretic peptide, cardiac index, and 6-min walk distance. Receiver operating characteristic analysis demonstrated that RA conduit function outperformed RVGLS and RVEF in differentiating PH-nonRVSD and HCs. However, a reduction in RA booster pump function was observed only in the PH-RVSD group (p < 0.001). During a median follow-up period of 97 (80-106) months, 45% of the included patients died. RA reservoir function was an independent predictor of all-cause mortality (HR = 0.963, 95% CI: 0.935-0.992, p = 0.014).</p><p><strong>Conclusions: </strong>RA function can detect right heart dysfunction prior to RVSD and monitor disease progression in patients with PH. Moreover, RA reservoir function independently predicts long-term prognosis.</p><p><strong>Critical relevance statement: </strong>Impairment of right atrial (RA) function, assessed by cardiac magnetic resonance feature tracking (CMR-FT), in pulmonary hypertension (PH) patients is sensitive in detecting right-sided heart dysfunction before right ventricular systolic dysfunction and can be utilized to monitor disease progression and long-term prognosis.</p><p><strong>Key points: </strong>RA function is sensitive in detecting early right heart dysfunction in PH patients. The disease progression of PH can be monitored by assessing RA function. RA function can serve as a tool for predicting long-term prognosis.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"115"},"PeriodicalIF":4.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in CT use in an emergency department in Western Australia: 2015-2022. 西澳大利亚州急诊科CT使用趋势:2015-2022
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-06-04 DOI: 10.1186/s13244-025-01993-9
Fouziah Almouqati, Thi Ninh Ha, Sharmani Barnard, Ashu Gupta, Elizabeth Thomas, Tracey Bhar, Colleen Taylor, Delia Hendrie
{"title":"Trends in CT use in an emergency department in Western Australia: 2015-2022.","authors":"Fouziah Almouqati, Thi Ninh Ha, Sharmani Barnard, Ashu Gupta, Elizabeth Thomas, Tracey Bhar, Colleen Taylor, Delia Hendrie","doi":"10.1186/s13244-025-01993-9","DOIUrl":"10.1186/s13244-025-01993-9","url":null,"abstract":"<p><strong>Objectives: </strong>We examined trends in CT use within the emergency department (ED) and their association with trends in subsequent hospital admission.</p><p><strong>Methods: </strong>This retrospective study analyzed administrative data on episodes of adults aged 18+ years who presented to the ED of a tertiary hospital in Western Australia (WA) from March 2015 to December 2022. Adjusted annual rates of CT use and hospital admission, stratified by CT status, were estimated using multivariable regression models.</p><p><strong>Results: </strong>Between 2015 and 2022, while the number of ED episodes increased by 8%, the number of CT scans rose by 90%. The crude rate of scans per 1000 ED episodes rose from 111 [95% CI: 108, 113] to 195 [95% CI: 192, 199]. After adjusting for variations in patients' characteristics, the rate increased from 118 [95% CI: 115, 121] to 173 [95% CI: 169, 176]. Admission rates were consistently higher for patients with CT but declined over time in both groups: from 47.6% [95% CI: 46.46, 48.75] to 42.01% [95% CI: 41.12, 42.9] for those with CT, and from 27.25% [95% CI: 26.86, 27.64] to 23.83% [95% CI: 23.47, 24.2] for those without. Compared to those without CT, the admission rate in those who underwent CT decreased by 2.17% [95% CI: 3.68, 0.66] over the period.</p><p><strong>Conclusions: </strong>CT use in the ED has continued to increase since 2015, coinciding with a greater decrease in admissions among patients who underwent CT. The appropriateness of this increase remains undetermined, warranting further investigation.</p><p><strong>Critical relevance statement: </strong>Given the ongoing efforts to optimize CT scan use, this study evaluates its current utilization in the emergency department and its usefulness in patient management, particularly in hospital admission.</p><p><strong>Key points: </strong>Examining CT use and usefulness is vital given ongoing optimization efforts. CT rates rose significantly, with a clear upward shift from 2020. This coincided with a greater drop in admission for CT patients than non-CT.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"116"},"PeriodicalIF":4.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of sarcopenia on the progression of chronic non-bacterial osteomyelitis. 肌肉减少症对慢性非细菌性骨髓炎进展的影响。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-06-04 DOI: 10.1186/s13244-025-02001-w
Daniel Vogele, Janine Akbulut, Franziska Müller-Reichart, Aleš Janda, Henner Morbach, Hermann J Girschick, Matthias C Schaal, Meinrad Beer, Clemens Benoit
{"title":"The impact of sarcopenia on the progression of chronic non-bacterial osteomyelitis.","authors":"Daniel Vogele, Janine Akbulut, Franziska Müller-Reichart, Aleš Janda, Henner Morbach, Hermann J Girschick, Matthias C Schaal, Meinrad Beer, Clemens Benoit","doi":"10.1186/s13244-025-02001-w","DOIUrl":"10.1186/s13244-025-02001-w","url":null,"abstract":"<p><strong>Objectives: </strong>Chronic non-bacterial osteomyelitis (CNO) is the most common autoinflammatory bone disease in children and adolescents. This study investigated the progression of CNO lesions during therapy and the potential impact of sarcopenia on disease progression, utilizing routine MRI.</p><p><strong>Methods: </strong>A retrospective analysis of MRI examinations was conducted on 29 children and adolescents with CNO. CNO lesions were segmented. Sarcopenia was assessed using the total psoas muscle index (PMI) at lumbar vertebral levels L3/4 and L4/5. Measurements were taken at four time points during the disease course (T1: baseline, T2-T4: follow-up). Based on the PMI, patients were classified as sarcopenic or non-sarcopenic, and the progression of CNO lesions and the impact of sarcopenia were analyzed.</p><p><strong>Results: </strong>A total of 29 patients, aged 1-16 years, were included in the study, with 13 males and 16 females. Patients with sarcopenia had a significantly larger mean lesion area (868.95 mm<sup>2</sup>, SD = 684.49) compared to those without sarcopenia (636.11 mm<sup>2</sup>, SD = 832.41); p = 0.042, d = 0.4). The comparison between the two patient groups revealed a consistently lower percentage reduction in lesion size for the sarcopenic patients at all time points. Notably, the difference between T1 and T3 was statistically significant (p = 0.045, d = 0.82).</p><p><strong>Conclusion: </strong>The present study indicates that sarcopenia may serve as a negative prognostic factor in the treatment of CNO. Incorporating sarcopenia assessment as an additional parameter in routine whole-body MRI examinations could enhance the evaluation process.</p><p><strong>Critical relevance statement: </strong>Sarcopenia can be assessed using routine whole-body MRI in patients with CNO and may serve as a negative prognostic factor, potentially enhancing the evaluation process.</p><p><strong>Key points: </strong>Whole-body MRI is crucial for diagnosing and monitoring CNO. Routine whole-body MRI in CNO patients can also be used to assess sarcopenia as an additional parameter. Sarcopenia may act as a negative prognostic factor in CNO treatment, potentially improving the evaluation process.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"117"},"PeriodicalIF":4.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Added value of 3D fast-field-echo (FRACTURE) sequences for cervical spondylosis diagnosis: a prospective multi-reader non-inferiority study. 三维快速场回波(骨折)序列对颈椎病诊断的附加价值:一项前瞻性多阅读器非效性研究。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-06-03 DOI: 10.1186/s13244-025-01997-5
Qizheng Wang, Xiaoying Xing, Zixian Zhang, Xiaoxi Ji, Shipei He, Yuxin Yang, Jiajia Xu, Qiang Zhao, Ning Lang
{"title":"Added value of 3D fast-field-echo (FRACTURE) sequences for cervical spondylosis diagnosis: a prospective multi-reader non-inferiority study.","authors":"Qizheng Wang, Xiaoying Xing, Zixian Zhang, Xiaoxi Ji, Shipei He, Yuxin Yang, Jiajia Xu, Qiang Zhao, Ning Lang","doi":"10.1186/s13244-025-01997-5","DOIUrl":"10.1186/s13244-025-01997-5","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the potential of fast field echo resembling a CT using restricted echo-spacing (FRACTURE) sequence to enhance conventional MRI in detecting bone abnormalities of cervical spondylosis.</p><p><strong>Materials and methods: </strong>137 consecutive patients with cervical spondylosis who underwent clinically indicated paired CT and MRI within 2 weeks between January and June 2024. After routine MRI, the 3D-FRACTURE sequences were performed. Three radiologists independently evaluated the data during three sessions: (1) CT with consensus, (2) routine MRI, and (3) FRACTURE, with a 4-week interval between sessions. Assessments included osteophytes, bony foraminal stenosis, posterior longitudinal ligament ossification (OPLL), their anatomical location, and diagnostic confidence, using CT as the reference standard. Inter- and intra-reader reproducibility was assessed using multi-rater Fleiss κ and the intraclass correlation coefficient (ICC), respectively. The non-inferiority assessment compared routine MRI/FRACTURE and CT diagnoses using a relative reduction margin of 0.5.</p><p><strong>Results: </strong>The study sample comprised 82 males and 55 females (age 56.9 ± 9.8 years). ICC indicated good to excellent inter-rater reliability for FRACTURE (osteophytes: ICC, 0.83-1.00; OPLL: ICC, 0.73-0.92; bony foraminal stenosis: ICC, 0.76-0.98), which was superior to conventional MRI (most ICC values < 0.7). The diagnostic confidence by FRACTURE sequences was significantly higher than by routine MRI (p < 0.001). Non-inferiority analysis demonstrated that FRACTURE and CT detection were similar for osteophyte, bony foraminal stenosis, and OPLL within a margin of 0.5.</p><p><strong>Conclusion: </strong>The FRACTURE sequence demonstrated comparable performance to CT in bone abnormalities detection in cervical spondylosis, superior to the routine MRI protocol.</p><p><strong>Critical relevance statement: </strong>The FRACTURE sequence addresses the limitations of conventional MRI in evaluating bone abnormalities, potentially minimizing radiation exposure and streamlining the diagnostic process for patients.</p><p><strong>Key points: </strong>MRI has advantages in the evaluation of cervical spondylosis, but is still insufficient in bone abnormalities evaluation. The FRACTURE sequence performed comparably to CT in bone abnormalities detection in cervical spondylosis. MRI with FRACTURE sequences may provide a non-ionizing method for assessing cervical spondylosis in some clinical settings.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"114"},"PeriodicalIF":4.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-model quantitative MRI of uterine cancers in precision medicine's era-a narrative review. 精准医学时代子宫癌多模型定量MRI研究述评。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-05-28 DOI: 10.1186/s13244-025-01965-z
Marco Gennarini, Rossella Canese, Silvia Capuani, Valentina Miceli, Federica Tomao, Innocenza Palaia, Valentina Zecca, Alessandra Maiuro, Ilaria Balba, Carlo Catalano, Stefania Maria Rita Rizzo, Lucia Manganaro
{"title":"Multi-model quantitative MRI of uterine cancers in precision medicine's era-a narrative review.","authors":"Marco Gennarini, Rossella Canese, Silvia Capuani, Valentina Miceli, Federica Tomao, Innocenza Palaia, Valentina Zecca, Alessandra Maiuro, Ilaria Balba, Carlo Catalano, Stefania Maria Rita Rizzo, Lucia Manganaro","doi":"10.1186/s13244-025-01965-z","DOIUrl":"10.1186/s13244-025-01965-z","url":null,"abstract":"<p><strong>Purpose: </strong>This review aims to summarize the current applications of quantitative MRI biomarkers in the staging, treatment response evaluation, and prognostication of endometrial (EC) and cervical cancer (CC). By focusing on functional imaging techniques, we explore how these biomarkers enhance personalized cancer management beyond traditional morphological assessments.</p><p><strong>Methods: </strong>A structured search of the PubMed database from January to May 2024 was conducted to identify relevant studies on quantitative MRI in uterine cancers. We included studies examining MRI biomarkers like Dynamic Contrast-Enhanced MRI (DCE-MRI), Diffusion-Weighted Imaging (DWI), and Magnetic Resonance Spectroscopy (MRS), emphasizing their roles in assessing tumor physiology, microstructure, and metabolic changes.</p><p><strong>Results: </strong>DCE-MRI provides valuable quantitative biomarkers such as Ktrans and Ve, which reflect microvascular characteristics and tumor aggressiveness, outperforming T2-weighted imaging in detecting critical factors like myometrial and cervical invasion. DWI, including advanced models like Intravoxel Incoherent Motion (IVIM), distinguishes between normal and cancerous tissue and correlates with tumor grade and treatment response. MRS identifies metabolic alterations, such as elevated choline and lipid signals, which serve as prognostic markers in uterine cancers.</p><p><strong>Conclusion: </strong>Quantitative MRI offers a noninvasive method to assess key biomarkers that inform prognosis and guide treatment decisions in uterine cancers. By providing insights into tumor biology, these imaging techniques represent a significant step forward in the precision medicine era, allowing for a more tailored therapeutic approach based on the unique pathological and molecular characteristics of each tumor.</p><p><strong>Critical relevance statement: </strong>Biomarkers obtained from MRI can provide useful quantitative information about the nature of uterine cancers and their prognosis, both at diagnosis and response assessment, allowing better therapeutic strategies to be prepared.</p><p><strong>Key points: </strong>Quantitative MRI improves diagnosis and management of uterine cancers through advanced imaging biomarkers. Quantitative MRI biomarkers enhance staging, prognosis, and treatment response assessment in uterine cancers. Quantitative MRI biomarkers support personalized treatment strategies and improve patient management in uterine cancers.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"113"},"PeriodicalIF":4.1,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12119420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solitary fibrous tumors from A to Z: a pictorial review with radiologic-pathologic correlation. 孤立性纤维性肿瘤从A到Z:影像学回顾与影像学病理相关性。
IF 4.1 2区 医学
Insights into Imaging Pub Date : 2025-05-28 DOI: 10.1186/s13244-025-01991-x
Fatmaelzahraa Abdelfattah Denewar, Mitsuru Takeuchi, Doaa Khedr, Fatma Mohamed Sherif, Farah A Shokeir, Misugi Urano, Ahmed E Eladl
{"title":"Solitary fibrous tumors from A to Z: a pictorial review with radiologic-pathologic correlation.","authors":"Fatmaelzahraa Abdelfattah Denewar, Mitsuru Takeuchi, Doaa Khedr, Fatma Mohamed Sherif, Farah A Shokeir, Misugi Urano, Ahmed E Eladl","doi":"10.1186/s13244-025-01991-x","DOIUrl":"10.1186/s13244-025-01991-x","url":null,"abstract":"<p><p>Solitary fibrous tumors (SFTs) represent a rare subset of mesenchymal neoplasms, affecting 1-2 per million people, with no gender preference. They demonstrate indolent behavior, frequent asymptomatic presentation, and widespread anatomical involvement. At imaging, SFTs typically appear as well-defined, predominantly hypervascular masses with varying degrees of cystic change and necrosis, though calcification is rare. Avid heterogeneous enhancement is typical following intravenous contrast administration, with multiple blood vessels observed at the periphery. Although findings on CT and MRI alone are generally nonspecific, a frequent feature of SFTs at MRI is the presence of rounded or linear low signal intensity foci on T1- and T2-weighted images, corresponding to the fibrous and collagenous content. Nevertheless, because the imaging features of SFTs overlap with those of many benign and malignant tumors, histologic confirmation is required for the final diagnosis. A comprehensive understanding of SFTs' multifaceted clinical, pathological, and radiological presentations across various organs is crucial for accurate diagnosis and effective management. CRITICAL RELEVANCE STATEMENT: A comprehensive understanding of the classic radiological and pathological features of solitary fibrous tumors across various organs is crucial for accurate diagnosis and effective management. KEY POINTS: Solitary fibrous tumors (SFTs) are rare hypervascular fibrous tumors with indolent behavior. Imaging features of SFTs overlap with many other tumors, necessitating histologic confirmation. Understanding SFTs' radiological presentations is crucial for accurate diagnosis and effective management.</p>","PeriodicalId":13639,"journal":{"name":"Insights into Imaging","volume":"16 1","pages":"112"},"PeriodicalIF":4.1,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信