Internal Medicine Journal最新文献

{"title":"Efficient use of the BioFire® FilmArray® Meningitis/Encephalitis Panel: a diagnostic stewardship approach.","authors":"Nalian H Ibrahim, Paul Kinsella, Eddie Chan, Katie Cronin, Katherine Bond","doi":"10.1111/imj.70391","DOIUrl":"https://doi.org/10.1111/imj.70391","url":null,"abstract":"<p><strong>Background: </strong>The BioFire® FilmArray® Meningitis/Encephalitis Panel (FA/ME) (BioFire Diagnostics, LLC, Salt Lake City, UT, USA) is a multiplex polymerase chain reaction (PCR) assay which detects pathogens causing community-acquired meningitis/encephalitis.</p><p><strong>Aims: </strong>This study aimed to evaluate the performance, clinical impact and potential of a diagnostic stewardship algorithm to optimise FA/ME use in an Australian tertiary hospital.</p><p><strong>Methods: </strong>This retrospective study evaluated microbiological data from 712 patients who underwent FA/ME testing between July 2018 and April 2024 at the Royal Melbourne Hospital and clinical data from a subset of 439 patients.</p><p><strong>Results: </strong>The FA/ME positivity rate was 12.2%. The panel showed 69.70% sensitivity and 93.04% specificity compared with comparator methods. FA/ME positivity was associated with targeted antimicrobial therapy and shorter hospital stays. The cerebrospinal fluid white cell count (WCC) strongly predicted FA/ME positivity (area under the curve = 0.80, P < 0.0001).</p><p><strong>Conclusions: </strong>A diagnostic stewardship algorithm employing a WCC threshold of >50 × 10⁶/L for FA/ME testing, with reflex testing of specimens with lower WCC on an alternative viral multiplex PCR, would have reduced annual costs from $23 302 (without stewardship) to $14 646, doubled the positivity rate to 29.54% and detected all clinically significant infections. This study provides insights into optimising FA/ME use in Australia to improve patient management.</p>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147456799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TSANZSRS Annual Scientific Meeting 2026 Abstracts","authors":"","doi":"10.1111/imj.70364","DOIUrl":"10.1111/imj.70364","url":null,"abstract":"","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 S1","pages":"4-202"},"PeriodicalIF":1.5,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/imj.70364","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147443264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trainee experiences and attitudes to phase 1 oncology trials: a cross-sectional survey of Australian medical oncology trainees","authors":"Roger Liang,&nbsp;Raja Chaganti,&nbsp;Su Saint Lee,&nbsp;Adnan Nagrial,&nbsp;Mark Wong","doi":"10.1111/imj.70306","DOIUrl":"10.1111/imj.70306","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Phase 1 oncology trials (POTs) are challenging to discuss with patients due to safety and efficacy uncertainties. In Australia, there is currently no formal training on POTs for oncology trainees.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This study aims to assess trainees' experiences and attitudes towards POTs to identify gaps that could inform the development of training and educational resources.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A 25-item online questionnaire was distributed to recently fellowed or current medical oncology advanced trainees in Australia. Responses regarding experience, perceptions and confidence in POT patient care and communication were analysed descriptively. Wilcoxon rank sum tests were performed to identify factors positively associated with confidence in POT domains.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty trainees completed the questionnaire. Although trainees typically had considerable clinical experience with POTs, half (<i>n</i> = 10) received ‘None’ or ‘Slight’ training, and only three (15%) evaluated the quality of their training to be above average. Trainees expressed confidence in assessing POT eligibility (mean score 3.55) and tumour response evaluation (mean score 3.3). Trainees reported lower confidence with discussing efficacy, toxicity and logistics of POTs (combined mean score 2.8). Higher levels of oncology experience (<i>P</i> = 0.011) and training in POTs (<i>P</i> = 0.034) were significantly associated with greater confidence in POT clinical domains.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Australian medical oncology trainees are highly involved in the care of patients on POTs despite receiving minimal training. Trainees report greater confidence in performing trial-specific clinical assessments than in discussing clinical aspects of POTs. This study highlights the need for formalised training and the development of education resources to enhance conduct and information provision regarding POTs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 3","pages":"425-432"},"PeriodicalIF":1.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145804406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary management of intermediate and high-risk pulmonary embolism in the era of mechanical thrombectomy: a local practice guideline","authors":"Anna Dunn,&nbsp;Elleanor Lee,&nbsp;Benjamin Harrison,&nbsp;Steel Scott,&nbsp;Joseph McCaffrey,&nbsp;Andrew Owen","doi":"10.1111/imj.70293","DOIUrl":"10.1111/imj.70293","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Risk stratification and management of pulmonary embolism (PE) continues to evolve, particularly for patients in the intermediate- and high-risk category, where treatment decisions are complicated by patient heterogeneity and limited guidance on reperfusion strategies. Catheter-based therapy (CBT) is becoming commonplace internationally; however, there is no published guidance on a standard approach to when to use these therapies in the Australian setting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>We aimed to develop a consensus-based, evidence-informed algorithm for risk stratification and management of PE at our institution, with a focus on effective utilisation of CBT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a retrospective audit of PE patients treated at our hospital. reviewed current evidence and international guidelines and convened a PE working group comprising respiratory physicians, interventional radiologists, intensive care physicians and anaesthetists. This group developed consensus guidelines and a standardised treatment algorithm.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The resulting treatment algorithm provides a clear, evidence-based approach to risk stratifying and managing PE patients, with a particular focus on the intermediate risk group. It facilitates uniform, multidisciplinary, physician-led decision-making and supports safe and effective integration of CBT. This treatment algorithm is novel in the Australian setting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>As CBT and other advanced therapies become increasingly available, the absence of national consensus guidelines presents a challenge. By integrating emerging clinical evidence expert opinion, we provide a pragmatic model that may support decision-making in similarly resourced centres.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 3","pages":"383-391"},"PeriodicalIF":1.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/imj.70293","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145846497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five-year outcomes of a dedicated, multidisciplinary clinic for decompensated cirrhosis","authors":"Natalie L. Y. Ngu,&nbsp;Edward Saxby,&nbsp;Thomas Worland,&nbsp;Stephanie Yung,&nbsp;Patricia Anderson,&nbsp;Jo Hunter,&nbsp;Erin Russell,&nbsp;Alexander Mitropoulos,&nbsp;Chania Lobo,&nbsp;Poh Wein Loh,&nbsp;William Sievert,&nbsp;Sally Bell,&nbsp;Suong Le","doi":"10.1111/imj.70321","DOIUrl":"10.1111/imj.70321","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Novel models of ambulatory care have been used in chronic disease management, but implementation in advanced chronic liver disease remains limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>We aimed to explore clinical outcomes of a multidisciplinary clinic for patients with chronic liver disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We performed a retrospective cohort study of patients attending a multidisciplinary liver clinic between February 2019 and May 2024. The clinic comprised co-located hepatologists, a dietitian, a pharmacist and an addiction medicine specialist, coordinated by a hepatology nurse. Patients accessed on-site point-of-care ultrasound, abdominal paracentesis and albumin infusions. The primary outcome was liver-related admission. Secondary outcomes were 12-month admission-free survival and change in liver disease prognostic scores at 3 and 6 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 285 patients were included, of whom 61% were men, 56% had alcohol-related liver disease and 95% had cirrhosis. The median baseline model for end-stage liver disease (MELD) score was 14.6 (interquartile range (IQR): 10.6–18.9) and 52% were in Child-Pugh B class at index appointment. The liver-related admission rate was 33% at a median of 546 days (IQR: 149–1095 days) from index appointment, and 12-month admission-free survival was 40.4% (IQR: 34.6–46.1). Median MELD improved at 3 months (12.8 months (IQR: 9.8–15.9 months), <i>P</i> &lt; 0.05) and plateaued by 6 months (11.9 months (IQR: 9.4–16.2 months), <i>P</i> = 0.29). The proportion of patients with ascites decreased at each time point (54% vs 35% vs 27%, <i>P</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Two-thirds of patients attending a multidisciplinary liver clinic had no subsequent liver-related admissions, with a median 18-month latency to admission in the remainder. Co-location of clinicians and supportive measures may contribute to these findings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 3","pages":"442-449"},"PeriodicalIF":1.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145948702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between retinal vascular disease and subsequent stroke risk: a nationwide cohort study","authors":"Yejin Lee,&nbsp;Seung Won Lee,&nbsp;Yoonjin Lee,&nbsp;Hohyun Jung,&nbsp;Youngoh Bae","doi":"10.1111/imj.70308","DOIUrl":"10.1111/imj.70308","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Retinal vascular diseases (RVDs), including retinal vascular occlusion (RVO), diabetic retinopathy (DR) and retinal haemorrhage (RH), share pathophysiologic features with cerebral microvasculature and may serve as indicators of subsequent stroke risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This study aimed to evaluate the associations of RVDs with ischemic stroke (IS) and hemorrhagic stroke (HS) in a nationwide cohort.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using data from the Korean National Health Insurance Service–National Sample Cohort (2002–2013), patients diagnosed with RVD were matched 1:10 with age- and sex-matched controls. Cox proportional hazards models were applied to estimate adjusted hazard ratios (aHRs) for IS and HS, adjusting for demographic, lifestyle and clinical covariates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 1365 patients with RVO, 975 with DR and 836 with RH were included. Compared with controls, patients with RVO (aHR: 1.82; 95% CI: 1.45–2.28), DR (aHR: 1.70, 95% CI: 1.32–2.21) and RH (aHR: 1.55, 95% CI: 1.18–2.05) had significantly higher IS risk. RVO was also associated with increased HS risk (aHR: 2.44, 95% CI: 1.39–4.29). Stratified analyses demonstrated stronger relative risks in individuals younger than 60 years. Socioeconomic disadvantage, obesity, smoking and heavy alcohol consumption further modified the risk of stroke.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>RVDs, particularly RVO, were significantly associated with elevated risks of both IS and HS. These findings highlight the potential value of retinal assessment in early identification of high-risk individuals and underscore the importance of tailored stroke prevention strategies, particularly in younger and socioeconomically vulnerable populations.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 3","pages":"433-441"},"PeriodicalIF":1.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145804390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotyping of acute heart failure with preserved ejection fraction: real-world outcomes in a cohort of older patients","authors":"Maria Livia Burzo *,&nbsp;Giuseppe De Matteis,&nbsp;Amato Serra,&nbsp;Davide Antonio Della Polla,&nbsp;Mariella Fuorlo,&nbsp;Maria Anna Nicolazzi,&nbsp;Benedetta Simeoni,&nbsp;Antonio Gasbarrini,&nbsp;Francesco Franceschi,&nbsp;Giovanni Gambassi,&nbsp;Marcello Covino","doi":"10.1111/imj.70324","DOIUrl":"10.1111/imj.70324","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Previous studies have identified distinct subgroups (phenogroups) of patients with heart failure with preserved ejection fraction (HFpEF).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This study aims to identify distinct phenotypes in older patients with HFpEF hospitalised for acute heart failure (AHF) and investigate the relationship between subgroups and outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Retrospective, single-center study, including patients ≥65 years hospitalised for AHF over a 4-year period. We used electronic medical records to collect clinical data, including hospital outcomes. Latent class analysis (LCA) was performed to identify clusters of clinical phenogroups. The primary outcome was all-cause in-hospital mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 770 patients were included. Based on LCA, three phenogroups were identified. Phenogroup 1 (<i>n</i> = 323) had both the lowest burden of comorbidities and N-terminal pro-brain natriuretic peptides (NT proBNP) values. Phenogroup 2 (<i>n</i> = 224) had the oldest patients (median age 82 years), the highest prevalence of women (62%) and atrial fibrillation and the worst right ventricular function. Phenogroup 3 (<i>n</i> = 223) consisted mainly of men (57%) and had a higher prevalence of diabetes, obesity and established cardiovascular disease and the worst renal function. Phenogroups 2 and 3 showed a significantly higher risk of primary outcome than phenogroup 1. In addition, survival analysis showed that phenogroup 2 had the worst prognosis, with more than double the risk of in-hospital death.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In this real-world cohort of older patients with HFpEF hospitalised for AHF, we identified three subgroups with significantly different features and prognoses. Phenomapping may be an effective tool to identify individuals most likely to experience adverse outcomes, providing a basis for phenotype-specific treatment strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 3","pages":"373-382"},"PeriodicalIF":1.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145948735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommendations for bone-directed therapy in patients with neuroendocrine tumour skeletal metastases at the New Zealand National Neuroendocrine Tumour Multidisciplinary Meeting","authors":"Gayle Radley,&nbsp;Marianne S Elston,&nbsp;Ben Lawrence,&nbsp;Veronica Boyle","doi":"10.1111/imj.70268","DOIUrl":"10.1111/imj.70268","url":null,"abstract":"<p>The role of anti-resorptive agents in patients with bone metastases from neuroendocrine neoplasms is unclear. Our aim was to review bone-specific treatment recommendations by the New Zealand National Neuroendocrine Tumour Multidisciplinary Meeting (MDM). Recommendations for bone-specific treatment were given at 29/365 MDMs (7.9%); 44.8% were confirmed to have received the recommended therapy. Bone-specific treatment recommendations were infrequent; there is a need for more data on the role of anti-resorptive agents in this group.</p>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 3","pages":"465-468"},"PeriodicalIF":1.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145966268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the American College of Surgeons National Surgical Quality Improvement Programme surgical risk calculator in predicting geriatric outcomes in patients with neck of femur fractures","authors":"Tessa Lo,&nbsp;Shiu Lai,&nbsp;Tanita Botha,&nbsp;Stephanie Than","doi":"10.1111/imj.70311","DOIUrl":"10.1111/imj.70311","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Hip fractures are associated with poor functional outcomes and increased mortality. The American College of Surgeons National Surgical Quality Improvement Programme (NSQIP) surgical risk calculator is an open access tool that estimates the probability of postoperative outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To externally validate the calculator in predicting geriatric outcomes (delirium, functional decline, pressure injury), 30-day inpatient mortality and discharge destination in patients aged 65 and older undergoing surgical fixation of neck of femur fractures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective single-centre cohort study of patients admitted from July 2022 to June 2023 to a large, metropolitan health service in Melbourne, Australia, was conducted. The calculator's performance was analysed using the area under the receiver operating characteristic curve (AUC), the Hosmer-Lemeshow test and the Brier score.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 305 patients in the study. Mean age was 82.4 ± 7.8 years and 215 (70.5%) were female. The calculator performed well for predicting delirium (AUC 0.859, 95% CI 0.811–0.902, Brier score 0.150), functional decline (AUC 0.883, 95% CI 0.826–0.935, Brier score 0.120) and mortality (AUC 0.854, 95% CI 0.774–0.917, Brier score 0.065). Results from the Hosmer-Lemeshow test for all of these outcomes demonstrated good calibration. The calculator had reduced performance in predicting discharge destination and pressure-injury risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The calculator is a moderately reliable predictor of delirium, functional decline and inpatient mortality in older patients who undergo hip fracture surgery. Further prospective research is required to validate it across other Australian healthcare settings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 3","pages":"401-409"},"PeriodicalIF":1.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145846462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Much ado about mentorship: a qualitative analysis of participant feedback from the inaugural Australian National Oncology Mentorship Programme","authors":"Udit Nindra,&nbsp;Gowri Shivasabesan,&nbsp;Rhiannon Mellor,&nbsp;Wei Chua,&nbsp;Deme Karikios,&nbsp;Bethan Richards,&nbsp;Jia Liu","doi":"10.1111/imj.70328","DOIUrl":"10.1111/imj.70328","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The inaugural Australian National Oncology Mentorship Programme 2023 (NOMP23) demonstrated that virtual matching of trainee oncologists (mentees) with senior clinicians (mentors) for a 1-year mentorship programme was associated with significant reductions in burnout and improved professional fulfilment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This sub-study sought to determine the bidirectional benefits of the programme for both mentees and mentors and unpack themes discussed at mentorship meetings to provide an insight into the benefit of top-down-led mentorship programmes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The NOMP23 programme methodology has been previously reported. Additionally, participants were invited to partake in semi-structured interviews that were transcribed and thematic analyses conducted to assess benefits, themes discussed and future directions to improve NOMP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 112 participants enrolled, 86% completed the baseline questionnaire, 62% completed the mid-programme questionnaire and 54% completed the end-of-programme questionnaire. Nine participants – four mentors and five mentees – were interviewed at NOMPs conclusion. A high level of connection between matched pairs with adequate ability for pairs to meet was identified. The most common topics discussed were career planning, professional fulfilment, research and time management. The benefits of the mentoring relationship fell into five themes: (i) professional guidance; (ii) personal connection; (iii) support and reassurance; (iv) external perspectives; and (v) future perspectives. Benefits of providing mentorship fell into two themes: (i) personal connection and (ii) future-proofing oncology as a profession.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Qualitative analyses of the NOMP23 programme demonstrated a positive effect on trainee and mentor well-being with benefits including personal guidance for trainees, fulfilment for mentors and instilling hope for the future.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13625,"journal":{"name":"Internal Medicine Journal","volume":"56 3","pages":"417-424"},"PeriodicalIF":1.5,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/imj.70328","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}