{"title":"A Review of the Fate and Effects of Selected Low- and No-Calorie Sweeteners and Their Probabilistic Risk to Aquatic Organisms.","authors":"Patrick D Guiney, Christopher M Holmes","doi":"10.1093/inteam/vjag122","DOIUrl":"https://doi.org/10.1093/inteam/vjag122","url":null,"abstract":"<p><p>Low- and no-calorie sweeteners (LNCS) are increasingly prevalent in food and beverages, with significant consumption growth in recent decades. This trend has led to heightened research into monitoring these non-nutritive sugar substitutes in environmental matrices, especially surface water. Many LNCS are excreted largely unchanged and are highly soluble in water, resulting in their detection in aquatic environments at concentrations ranging from ng/L to µg/L, primarily due to municipal or household wastewater discharge. While LNCS are generally considered safe for human consumption with established Acceptable Daily Intakes (ADI), their ecological risks remain an interest due to their global ubiquitous use, eventual entry into surface waters, and limited use of contemporary ecological risk assessment methodologies for these substances. We investigated five common LNCS: aspartame (ASP), cyclamate (CYC), saccharin (SAC), sucralose (SUC), and steviol glycosides (SG), an emerging natural sweetener. Utilizing data from Euromonitor International, we assessed global consumption patterns in food and beverages and generated probabilistic exposure distributions using models for the U.S. (iSTREEM®) and Europe (HydroFATE). These were compared to retrospective exposure values based on 75 curated aquatic concentration monitoring studies spanning the world. A relative exposure index was created to contextualize modeled results globally across seven regions. We integrated comprehensive aquatic ecotoxicity data from 54 additional studies with our exposure assessments for a probabilistic ecological risk evaluation. Predicted no-effect concentration (PNEC) values were established for ASP (68.8 µg/L), CYC (20-20,000 µg/L), SAC (2,000 µg/L), SG (10,000 µg/L), and SUC (9,300 µg/L). These PNECs were significantly higher than predicted environmental concentrations and observed data by one to four orders of magnitude, depending on the LNCS and exposure scenario. This suggests high margins of safety and minimal ecological risk at current usage levels. Routine updates of this risk assessment are recommended to maintain on-going aquatic safety as LNCS usage evolves.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148663780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yajie Gao, Marja Roitto, Teng Hu, Tapani Jokiniemi, Mari Sandell, Hanna L Tuomisto
{"title":"Comparing farm-level carbon footprint calculators for dairy production with a case study of Viikki Research Farm in Finland.","authors":"Yajie Gao, Marja Roitto, Teng Hu, Tapani Jokiniemi, Mari Sandell, Hanna L Tuomisto","doi":"10.1093/inteam/vjag127","DOIUrl":"https://doi.org/10.1093/inteam/vjag127","url":null,"abstract":"<p><p>Dairy farms are under pressure to reduce greenhouse gas (GHG) emissions. Various carbon footprint (CF) accounting tools have been developed for calculating GHG emissions and pinpointing hotspots to support mitigation efforts. However, inconsistent methodologies often lead to variations of their results, unclear discrepancies pose barriers to credible reporting and decision making. Five open access, farm-level CF accounting tools applicable to EU livestock production were evaluated and compared for their methodologies. They were further tested through a case study of a dairy Farm in Finland for their consistency in quantifying emissions of milk production. The sensitivity of each tool was analyzed across nine mitigation scenarios to evaluate their practical utility in guiding mitigation strategies. A significant variability in total GHG emissions was observed, ranging from 415 to 913 t CO2 eq y-1, derived mainly from differences in scopes and the adoption of varying method tiers (in IPCC 2006 or IPCC 2019). While enteric fermentation and feed production remained the primary emission sources across all tools, their contributions fluctuated based on calculation methods. Solagro and the Cool Farm Tool were most responsive to mitigation strategies regarding manure management and yield improvements, while GLEAM-i and CAP'2ER (level 1) lacked the flexibility to model specific management shifts. The lack of methodological harmony causes inconsistent results, requiring careful tool selection to align with specific goals and data availability. Methodological frameworks can be harmonized with evolving standards (Product environmental footprint category rules for dairy products), meanwhile adapting scientific advances into calculations to ensure transparency and comparability.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148669367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giulia Minolfi, Fabio Rosada, Elisa Giubilato, Alex Zabeo, Stephane Belbèze, Virginie Derycke, Timo Tarvainen, Isadora Antoniano Villalobos, Elena Semenzin, Lisa Pizzol
{"title":"Regional risk assessment Part I: prioritization of potentially contaminated sites.","authors":"Giulia Minolfi, Fabio Rosada, Elisa Giubilato, Alex Zabeo, Stephane Belbèze, Virginie Derycke, Timo Tarvainen, Isadora Antoniano Villalobos, Elena Semenzin, Lisa Pizzol","doi":"10.1093/inteam/vjag123","DOIUrl":"https://doi.org/10.1093/inteam/vjag123","url":null,"abstract":"<p><p>Soil contamination remains a critical barrier to endurable land use and environmental health worldwide. A stepwise and risk-based approach to identify, assess and manage potentially contaminated sites across complex land uses, is presented. Unlike traditional site-specific risk assessments, which are often limited to detailed studies of individual locations, this large-scale approach (known as regional risk assessment - RRA) integrates diverse data sources - historical or current data on anthropogenic activities - with pathways relevance information and receptors vulnerability to support prioritisation when dealing with a very large number of sites. The methodology is implemented within a GIS-based framework, and integrate spatial data on hazards, pathways, and receptors to produce regional-scale risk maps. The output provides a relative ranking of potentially contaminated sites based on estimated risk levels, supporting the prioritisation of sites requiring further site-specific investigation or remediation. Applied to the metropolitan area of Toulouse, the framework demonstrates its applicability across urban and peri-urban landscapes. This methodology responds to emerging regulatory requirements, such as the Soil Monitoring and Resilience Directive, and offers practical support to strategic planning efforts aligned with EU policy initiatives. By enabling more efficient and risk-based site management, the framework contributes to the protection of human health and the land resources.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148619509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adriana C Bejarano, Ann-Hayward Walker, Stephen R Gittings
{"title":"Scientific Storytelling: Considerations and Implications for Research Communication and Engagement.","authors":"Adriana C Bejarano, Ann-Hayward Walker, Stephen R Gittings","doi":"10.1093/inteam/vjag119","DOIUrl":"https://doi.org/10.1093/inteam/vjag119","url":null,"abstract":"<p><p>Effective engagement between scientists and layperson audiences can enhance public understanding of scientific research, strengthen trust and foster support for scientific advancement. Among the various forms of science communication strategies available, narrative approaches, particularly storytelling, have gained attention for their ability to frame scientific findings within meaningful contexts. When used as a complementary form to traditional formats (e.g., technical documents), storytelling can help scientists connect more personally with layperson audiences and strengthen the impact of the intended message. By reducing cognitive barriers and presenting information in clear, relatable and human-centered ways, storytelling can support the interpretation of complex scientific concepts across diverse contexts. This paper examines the foundations and elements of scientific storytelling, including relevant cognitive and psychological principles, narrative structure and the role of soft skills in effective communication. It also explores challenges and ethical considerations associated with narrative approaches and illustrates how storytelling principles have been applied through selected case studies in environmental sciences. These insights highlight how thoughtful and context-appropriate use of storytelling can broaden the reach, impact and appreciation of scientific research, support shared understanding and strengthen engagement and connections between science and society.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148602413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mathieu Renaud, Louveline Lépeule, Laura Centeno, Dominique Grandjean, Florian Breider, Sophie Campiche, Benoit Jean Dominique Ferrari
{"title":"Natural variability of four ecotoxicological test species in soils-proof of concept at a regional scale and first step towards a national reference response.","authors":"Mathieu Renaud, Louveline Lépeule, Laura Centeno, Dominique Grandjean, Florian Breider, Sophie Campiche, Benoit Jean Dominique Ferrari","doi":"10.1093/inteam/vjag114","DOIUrl":"https://doi.org/10.1093/inteam/vjag114","url":null,"abstract":"<p><p>Ecotoxicological indicators could be an important tool in soil monitoring programs to help understand the effects and ecotoxicity of potentially contaminated soils. For soil, one of the most complex environmental matrices, they can elucidate questions regarding the bioavailability of contaminants. However, the use of ecotoxicological indicators in retrospective risk assessment, in particular monitoring, struggles with the lack of adequate reference sites and/or responses. In this study we aim to define a reference or normal response range by evaluating the natural variability in soils of 4 ecotoxicological indicators species (Folsomia candida, Enchytraeus crypticus, Brassica napus, Allium cepa) including 3 endpoints (reproduction, shoot length and root length). Two approaches were used to establish the normal response range, one based on variability towards a control response (minimum detectable differences and maximum tolerable inhibition) and a percentile response based on the variability within the natural test soils. For this, 32 natural soils from the Jura region of Switzerland were tested with the 4 ecotoxicological indicators. To ensure responses were not driven by background chemical concentrations samples were analysed for metal concentrations, as regulated by Swiss legislation and for 144 pesticide residuess. Pesticides concentrations in the selected soils were very low and higher metals concentrations were mostly of geogenic origin and did not appear to influence biological responses. Regarding biological variability, it was possible to determine normal operating ranges for all four ecotoxicological test species, and the percentile approach seems better suited for natural soils from the Jura region, for which LUFA 2.2 is not always very representative. The percentile approach shows a high potential as a methodology for setting reference response ranges based on the natural variability in soils. The approach now needs to be compared to potentially contaminated soils and extended to other biogeochemical regions to allow its use in monitoring programs.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148602354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Damaris Cristine Marios Ferreira Pinto, Elisa Castro Wille Nonino, Natália Vita de Albuquerque, Andrezza Canavez Di Pietro Micali, Desiree Schuck Cigaran, Cynthia Pestana, Daniela Morais Leme
{"title":"The applicability of New Approach Methodologies (NAMs) in aquatic hazard and risk assessments of cosmetic ingredients: a case study of UV filters.","authors":"Damaris Cristine Marios Ferreira Pinto, Elisa Castro Wille Nonino, Natália Vita de Albuquerque, Andrezza Canavez Di Pietro Micali, Desiree Schuck Cigaran, Cynthia Pestana, Daniela Morais Leme","doi":"10.1093/inteam/vjag121","DOIUrl":"https://doi.org/10.1093/inteam/vjag121","url":null,"abstract":"<p><p>Transitioning to Safe and Sustainable by Design (SSbD) in cosmetics requires reliable non-animal methods for early ingredient selection. This study proposes an approach that integrates New Approach Methodologies (NAMs) to screen for persistence, bioaccumulation, and toxicity (PBT), endocrine active substance (EAS), and environmental risk (predicted environmental concentration-to-predicted no-effect concentration (PEC/PNEC) ratio) to support the selection of less toxic ingredients for product formulation. A case study of nine organic ultraviolet (UV) filters commonly used in cosmetics, with exposure scenarios adapted to the Brazilian context, was used to demonstrate the applicability of the proposed approach. The selected UV filters were: bis-ethylhexyloxyphenol methoxyphenyl triazine (BEMT), butyl methoxydibenzoylmethane (BMD), diethylamino hydroxybenzoyl hexyl benzoate (DHHB), ethylhexyl methoxycinnamate (EMC), ethylhexyl salicylate (ES), ethylhexyl triazone (ET), octocrylene (OC), phenylbenzimidazole sulfonic acid (PSA), and tris- biphenyl triazine (TBT). For hazard predictions, PBT and endocrine activity were predicted using the freely available in silico tools QSAR Toolbox, VEGA, JANUS, Danish QSAR, T.E.S.T., and Endocrine Disruptome. In vitro data from the EPA ToxCast were included in the EAS evaluation. Using a majority consensus approach for integrating the in silico tools, ER activity was predicted only for ES. ToxCast data showed EAS potential for three of the four UV filters: OC and BMD (ER and AR antagonists), and ES as an ER agonist. Although results indicated some ingredients were toxic to aquatic life, under a conservative exposure scenario, PEC/PNEC ratios for water and sediment indicated acceptable environmental margins of exposure for PSA, BEMT, DHHB and TBT. In conclusion, hazard and risk assessments using NAMs data can be employed to identify UV filters of lower concern for aquatic environments and support the implementation of SSbD within the cosmetic industry.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J A Rezende, O A de Carvalho Júnior, R P Scorza Júnior
{"title":"Environmental risk assessment of atrazine in a tropical river basin using regulatory exposure modeling in Brazil.","authors":"J A Rezende, O A de Carvalho Júnior, R P Scorza Júnior","doi":"10.1093/inteam/vjag120","DOIUrl":"https://doi.org/10.1093/inteam/vjag120","url":null,"abstract":"<p><p>Mathematical modeling and predictive simulation have improved Environmental Risk Assessment (ERA) of pesticides, particularly in exposure characterization. This research applied the regulatory tool Pesticide in Water Calculator (PWC) to estimate environmental exposure to atrazine in surface waters of the Rio Preto Basin (Federal District, Brazil), a predominantly agricultural region within the Cerrado biome. Six conservative Tier 1 exposure scenarios for maize were developed to represent worst-case conditions under local edaphoclimatic and land-use conditions. Estimated Environmental Concentrations (EECs) were integrated with standard aquatic ecotoxicological endpoints to calculate Risk Quotients (RQs). Risk quotients (RQs) exceeded regulatory Levels of Concern (LOCs) for some exposure scenarios, particularly for algae, indicating greater sensitivity of primary producers among the evaluated taxa. A Tier 2 refinement incorporating conservation practices as mitigation measures reduced exposure estimates and associated risk. Refining exposure scenarios reduced atrazine EECs by more than 50%, rendering the risk acceptable under the analyzed conditions. The findings indicate that the development of exposure scenarios under tropical environmental conditions enhances the representativeness of risk estimates, strengthens the ERA process, and provides robust technical support for regulatory decision-making.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integrated assessment of wastewater pollution in a karstic coastal lagoon: linking nutrients, caffeine, stable isotopes, and fish physiological responses.","authors":"Xurxo Barral-Pintos, Jorge Herrera-Silveira, Elsa Noreña-Barroso, Gabriela Gaxiola, Vanesa Papiol","doi":"10.1093/inteam/vjag118","DOIUrl":"https://doi.org/10.1093/inteam/vjag118","url":null,"abstract":"<p><p>Coastal water pollution is a global problem, especially in karstic areas, where pollutants from point and non-point sources reach coastal systems. The Chelem Lagoon in the Yucatan Peninsula exemplifies such environments, where the presence and effects of pollutants have been previously reported. This study presents and evaluates an integrated assessment framework to characterize pollution sources and ecotoxicological impacts in complex coastal systems. This approach combines nutrient concentrations, caffeine (as an urban wastewater tracer), carbon and nitrogen stable isotopes, and a suite of physiological and biochemical biomarkers in the resident fish Sphoeroides testudineus and provides a valuable basis for informing environmental management in karstic environments. The results showed that our integrated approach successfully defined a longitudinal pollution gradient and revealed a complex, tissue-specific physiological response in S. testudineus. In the mid-lagoon (Chuburna area), the presence of caffeine indicated recent or ongoing wastewater inputs. The pollution gradient induced distinct stress profiles: the east (Progreso), characterized by high ammonium concentrations, showed biomarker responses consistent with localized physiological stress, including increased liver protein oxidation. Conversely, the west (accumulation zone), characterized by higher nitrate concentrations and δ15N in suspended and sedimentary particulate organic matter, exhibited different biomarker responses, including muscle acetylcholinesterase inhibition, catalase depletion, and higher liver lipid peroxidation. Overall, this integrated multi-biomarker framework, using S. testudineus as a sentinel species, provides a useful basis for characterising complex pollution patterns and assessing wastewater influence in coastal karstic lagoons. This framework is scalable and can support environmental monitoring and management in similar high-priority ecosystems.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oluwafemi Adebayo Oyewole, Samuel Adeniyi Oyegbade, Abdullah Albaqami
{"title":"Nanotechnology and Plant-Microbe Interactions: Enhancing Symbiotic Relationships for Crop Resilience.","authors":"Oluwafemi Adebayo Oyewole, Samuel Adeniyi Oyegbade, Abdullah Albaqami","doi":"10.1093/inteam/vjag117","DOIUrl":"https://doi.org/10.1093/inteam/vjag117","url":null,"abstract":"<p><p>The integration of nanomaterials (NMs) with plant-beneficial microorganisms has emerged as a promising strategy to improve crop resilience to abiotic stresses. Evidence from multiple studies indicates that NM-microbe co-application often enhances plant growth, nutrient uptake, biomass accumulation, and stress tolerance more effectively than either approach alone. Under drought and salinity stress, these combinations help maintain ionic balance, particularly higher K+/Na+ ratios, sustain photosynthesis, and reduce oxidative damage by increasing the activities of antioxidant enzymes such as superoxide dismutase, catalase, and peroxidase. Nanoparticles, including ZnO, Fe3O4, and SiO2, when combined with plant growth-promoting rhizobacteria (PGPR) or arbuscular mycorrhizal fungi (AMF), stimulate root development, increasing water and nutrient acquisition. Additionally, NMs can reshape rhizosphere microbial communities by enriching beneficial taxa such as Pseudomonas, Bacillus, and Trichoderma while suppressing certain phytopathogens. Nanoformulated fertilizers and micronutrients further enhance nutrient use efficiency and may reduce dependence on conventional agrochemicals, supporting sustainable agricultural practices. However, the benefits of NM-microbe integration are not universal. Several studies report that some nanomaterials can inhibit beneficial microorganisms, including nitrogen-fixing bacteria and AMF, at concentrations only slightly above stimulatory levels, highlighting a narrow safety margin. Concerns also remain regarding NM persistence, soil-dependent mobility, trophic transfer through food webs, and potential disruption of soil microbial communities. This review evaluates both the advantages and risks of NM-microbe interactions, emphasizing the importance of dose, soil characteristics, and microbial strain selection. Current evidence, largely derived from short-term laboratory studies, remains insufficient to support widespread field application without long-term ecological monitoring, standardized assessment protocols, and evaluation of economic feasibility for smallholder farming systems.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irantzu Garmendia-Aguirre, Mónica Martinez-Junquera, Julio Gómez, Elvira Villaro Ábalos, Hubert Rauscher, Lya G Soeteman-Hernández, Ana Serrano-Lotina
{"title":"Navigating through Safe-and-Sustainable-by-Design (SSbD): Scoping Analysis with functionalized graphene oxide as a case study.","authors":"Irantzu Garmendia-Aguirre, Mónica Martinez-Junquera, Julio Gómez, Elvira Villaro Ábalos, Hubert Rauscher, Lya G Soeteman-Hernández, Ana Serrano-Lotina","doi":"10.1093/inteam/vjag115","DOIUrl":"https://doi.org/10.1093/inteam/vjag115","url":null,"abstract":"<p><p>Safe and sustainable by design (SSbD) is key to the European Chemicals Strategy for Sustainability (CSS), which aims to reduce the negative impacts of chemicals, materials and products introduced onto the EU market on human health and the environment associated. The EC Joint Research Centre (JRC) SSbD methodological guidance published in 2024 introduced a Scoping Analysis that supports the contextualization of the assessment phase of the SSbD framework in R&I activities that now has been included in the revision of the SSbD framework. This article describes the application of the Scoping Analysis to a case study on graphene oxide functionalized with chitosan (N-acetylglucosamine) to be used as an alternative to the currently used flame-retardant additives for its application in battery cases in electric vehicles. The SSbD scoping analysis supports safety and sustainability assessments and identifies areas for improvement iteratively as the innovation progress towards full SSbD implementation.</p>","PeriodicalId":13557,"journal":{"name":"Integrated Environmental Assessment and Management","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}