Infectious diseases now最新文献_第5页

Pooled sample testing strategy for Aspergillus IgG-IgM serology in Uganda: A proof-of-concept and cost-effectiveness analysis 乌干达曲霉菌 IgG-IgM 血清学联合样本检测策略：概念验证和成本效益分析。

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-07 DOI: 10.1016/j.idnow.2024.104936

Felix Bongomin , Quinto Ogwang , Shamim Katusabe , Claudine Mukashyaka , Joseph Baruch Baluku , Martha Namusobya , Norman van Rhijn , David W. Denning

引用次数: 0

The role of systemic corticosteroids when treating infections in adult primary care 在成人初级保健中治疗感染时全身使用皮质类固醇的作用。

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-01 DOI: 10.1016/j.idnow.2024.104925

Jean-Pierre Bru

{"title":"The role of systemic corticosteroids when treating infections in adult primary care","authors":"Jean-Pierre Bru","doi":"10.1016/j.idnow.2024.104925","DOIUrl":"10.1016/j.idnow.2024.104925","url":null,"abstract":"<div><p>Inflammatory response to aggressive infection is responsible not only for symptoms, especially pain, but also for severity, when the inflammatory cascade is violent, and provokes a deleterious cytokine storm.</p><p>Due to their anti-inflammatory properties, corticosteroids are widely used in ambulatory medical practice. While their beneficial effects on some symptoms, particularly pain, are undeniable, so are the risks associated with their other properties (immunosuppression, neurostimulation, hypermetabolism), even during short-term administration at low doses.</p><p>Following robust risk–benefit assessment, the role of corticosteroids in the treatment of a number of serious pathologies (septic shock, severe acute community-acquired pneumonia, and some forms of bacterial meningitis such as hypoxia-related pneumocystosis, etc.) is presently well-defined. The objective of this review is not to consider the role of corticosteroids in cases of severe infectious disease necessitating hospital-based management, or in contexts where there exists a clear consensus in favor of their utilization.</p><p>This work represents an attempt to apprise the current state of knowledge on the interest of corticosteroids in the management of infections in adults in primary care.</p><p>Corticosteroid treatment can be beneficial with regard to some of the infectious diseases treated in primary care. That said, when the benefit actually appears, it remains modest, and the level of evidence supporting the utilization of corticosteroids is low or moderate. In no situation is an indication for corticosteroid therapy official or even, at the very least, indisputable.</p><p>With regard to the pathologies under consideration, corticosteroid prescription must imperatively be based on impeccable characterization of the clinical situation, diagnosis of severity, knowledge of the disease field, and risk–benefit assessment for a given patient.</p></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"54 4","pages":"Article 104925"},"PeriodicalIF":3.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666991924000873/pdfft?md5=8c1ab84d6438e368c9223f941cf1ecbe&pid=1-s2.0-S2666991924000873-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141070922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sports and Immunity, from the recreational to the elite athlete 运动与免疫，从休闲运动员到精英运动员。

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-01 DOI: 10.1016/j.idnow.2024.104893

Richard Baskerville , Linda Castell , Stéphane Bermon

{"title":"Sports and Immunity, from the recreational to the elite athlete","authors":"Richard Baskerville , Linda Castell , Stéphane Bermon","doi":"10.1016/j.idnow.2024.104893","DOIUrl":"10.1016/j.idnow.2024.104893","url":null,"abstract":"<div><p>The pivotal role of the immune system in physical activity is well-established. While interactions are complex, they tend to constitute discrete immune responses. Moderate intensity exercise causes leukocytosis with a mild anti-inflammatory cytokine profile and immunoenhancement. Above a threshold of intensity, lactate-mediated IL-6 release causes a proinflammatory state followed by a depressed inflammatory state, which stimulates immune adaptation and longer term cardiometabolic enhancement. Exercise-related immune responses are modulated by sex, age and immunonutrition. At all ability levels, these factors collectively affect the immune balance between enhancement or overload and dysfunction. Excessive training, mental stress or insufficient recovery risks immune cell exhaustion and hypothalamic pituitary axis (HPA) stress responses causing immunodepression with negative impacts on performance or general health. Participation in sport provides additional immune benefits in terms of ensuring regularity, social inclusion, mental well-being and healthier life choices in terms of diet and reduced smoking and alcohol, thereby consolidating healthy lifestyles and longer term health. Significant differences exist between recreational and professional athletes in terms of inherent characteristics, training resilience and additional stresses arising from competition schedules, travel-related infections and stress. Exercise immunology examines the central role of immunity in exercise physiology and straddles multiple disciplines ranging from neuroendocrinology to nutrition and genetics, with the aim of guiding athletes to train optimally and safely. This review provides a brief outline of the main interactions of immunity and exercise, some influencing factors, and current guidance on maintaining immune health.</p></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"54 4","pages":"Article 104893"},"PeriodicalIF":3.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666991924000484/pdfft?md5=b8cf2769ce8f88f2aea5d31c4fa52a0c&pid=1-s2.0-S2666991924000484-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140293457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Freshwater sports and infectious diseases: A narrative review 淡水运动与传染病：叙述性综述。

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-01 DOI: 10.1016/j.idnow.2024.104883

Hugues Delamare , Alexandra Septfons , Serge Alfandari , Alexandra Mailles

{"title":"Freshwater sports and infectious diseases: A narrative review","authors":"Hugues Delamare , Alexandra Septfons , Serge Alfandari , Alexandra Mailles","doi":"10.1016/j.idnow.2024.104883","DOIUrl":"10.1016/j.idnow.2024.104883","url":null,"abstract":"<div><p>Freshwater sports involve a wide range of practices leading to contact with soil and water that can entail exposure to agents of potential infectious diseases. The pathogens can be multiple (bacteria, parasites, viruses, fungi), and be either well-known or more unfamiliar and exotic.</p><p>We conducted a literature review to describe various infections contracted following exposure to water and mud during freshwater sport activities. Out of the 1011 articles identified, 50 were finally included. Our findings encompassed bacterial infections (leptospirosis and gastrointestinal infections); parasitic infections (schistosomiasis, cercarial dermatitis); viral infections (norovirus and other gastrointestinal viruses; seaweed contamination; and fungal infections. These infections were reported in various countries worldwide among diverse freshwater sport activities, including swimming, surfing, kayaking, as well as extreme sports such as adventure races and mud runs. Water sports in freshwater can expose participants to infectious risks according to geographical location and type of sport. Because regular sport practice is beneficial for health, freshwater sports should not be avoided due to potential exposure to pathogens; that much said, certain precautions should be taken. In addition to adoption of preventive measures, participants should be informed about infectious risks and seek medical advice if symptoms appear after exposure. Current guidelines for assessment of bathing water quality do not suffice to ensure comprehensive evaluation of freshwater quality. Event organizers are called upon to pay close attention to environmental factors and meteorological events, to conduct timely sensitization campaigns, and to enforce appropriate safety measures.</p></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"54 4","pages":"Article 104883"},"PeriodicalIF":3.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666991924000381/pdfft?md5=0ee357e3cfc76adbf5454c45c915837f&pid=1-s2.0-S2666991924000381-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Staphylococcus aureus: No ticket for the Paris 2024 Olympic Games! 金黄色葡萄球菌：没有 2024 年巴黎奥运会的入场券！

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-01 DOI: 10.1016/j.idnow.2024.104882

Anne-Lise Maucotel, Camille Kolenda, Frédéric Laurent, Anne Tristan

{"title":"Staphylococcus aureus: No ticket for the Paris 2024 Olympic Games!","authors":"Anne-Lise Maucotel, Camille Kolenda, Frédéric Laurent, Anne Tristan","doi":"10.1016/j.idnow.2024.104882","DOIUrl":"10.1016/j.idnow.2024.104882","url":null,"abstract":"<div><p>Athletes are vulnerable to <em>Staphylococcus aureus</em> infections due to skin-to-skin contact and skin abrasions during training and competitions involving sharied sport equipment or toiletries, which promote the spread of the bacteria between athletes and within sport teams. This results not only in higher prevalence of <em>S.aureus</em> carriage among athletes compared to the general population, but also in outbreaks of infections, particularly skin infections, within sports teams. To limit the spread of <em>S. aureus</em> among athletes, a decolonization protocol can be applied when clustered cases of <em>S. aureus</em> infections occur, especially if Panton-Valentine leukocidin-producing strains are implicated. Finally, to avoid exposing athletes to <em>S.aureus</em> transmission/colonization, it is recommended to establish strict and clearly formulated individual and collective hygiene rules and to regularly disinfect shared sports equipment.</p></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"54 4","pages":"Article 104882"},"PeriodicalIF":3.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266699192400037X/pdfft?md5=43386285d359f36fc53e054814c4a056&pid=1-s2.0-S266699192400037X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CV2 : Editorial board CV2：编辑委员会

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-01 DOI: 10.1016/S2666-9919(24)00089-7

引用次数: 0

Sport and infections 运动与感染。

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-01 DOI: 10.1016/j.idnow.2024.104920

Jean-Paul Stahl (Editor-in-chief of Infectious Diseases Now)

引用次数: 0

Infectious risks associated with outdoor sports activities 与户外体育活动相关的感染风险。

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-01 DOI: 10.1016/j.idnow.2024.104862

Aurélie Velay , Florian Baquer , Julie Brunet , Julie Denis , Assilina Parfut , Emilie Talagrand-Reboul , Yves Hansmann

{"title":"Infectious risks associated with outdoor sports activities","authors":"Aurélie Velay , Florian Baquer , Julie Brunet , Julie Denis , Assilina Parfut , Emilie Talagrand-Reboul , Yves Hansmann","doi":"10.1016/j.idnow.2024.104862","DOIUrl":"10.1016/j.idnow.2024.104862","url":null,"abstract":"<div><p>In France, outdoor sports and activities account for 36% of sports engagement, making outdoor venues the most popular settings for sports participation. Discussing the links between sports and health almost always highlights the beneficial impact of engaging in sports. However, due to a lack of specific notifications, infectious risks are not subject to epidemiological monitoring, and need to be better understood. Since the practice of outdoor sports has become part and parcel of many individuals’ daily routines, it is essential to more accurately characterize the knowledge we have gained about the risks associated with exposure. However, directly associating the practice of a sport with an elevated risk of infectious diseases is a challenging endeavor. Sociological factors based on risk awareness and adoption of protective behaviors in response to the risk are crucial to the orientation of prevention efforts.</p><p>This review deals with several (bacteriological, viral, parasitic, and mycological) infectious risks related to outdoor activities practiced in a natural field via contamination routes such as tick-bite, enteric pathogen, skin, and aerosol transmission. We have also detailed a number of preventive measures taking into account the outdoor setting (e.g., vaccination).</p></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"54 4","pages":"Article 104862"},"PeriodicalIF":3.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666991924000174/pdfft?md5=512f327686626d988b03aac425fa567f&pid=1-s2.0-S2666991924000174-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141283651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological surveillance and infectious disease outbreaks during mass international summertime sports gatherings: A narrative review 夏季国际体育运动群众集会期间的流行病监测和传染病爆发：叙述性综述。

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-06-01 DOI: 10.1016/j.idnow.2024.104889

Yves Gallien , Nelly Fournet , Hugues Delamare , Laetitia Haroutunian , Arnaud Tarantola

{"title":"Epidemiological surveillance and infectious disease outbreaks during mass international summertime sports gatherings: A narrative review","authors":"Yves Gallien , Nelly Fournet , Hugues Delamare , Laetitia Haroutunian , Arnaud Tarantola","doi":"10.1016/j.idnow.2024.104889","DOIUrl":"10.1016/j.idnow.2024.104889","url":null,"abstract":"<div><p>The XXXIII<sup>rd</sup> Paris Summer Olympics followed by the XVII<sup>th</sup> Paralympics Games will take place in France, predominantly in and around Paris, from July 26 to September 8, 2024. Public health stakeholders and decision-makers are called upon to set up or strengthen surveillance systems in areas hosting Olympic or Paralympic Games (OPGs) or large-scale international competitions, the objective being to detect and manage outbreaks should they occur during that period. We undertook a narrative review of the literature so as to identify major reported infectious disease outbreaks linked with or during OPGs / international sporting events during warm seasons. Our review found that since 1992, Summer Olympic and Paralympic games and international football competitions have been associated with sporadic cases of infectious diseases, principally respiratory, gastrointestinal/foodborne, but not with any major communicable or other infectious disease outbreak. Communicable disease risks should be assessed for the population taken as a whole, an integrated ecosystem with several population compartments potentially exchanging pathogens among one another. Although the Games afford an opportunity to federate or invent new surveillance systems to fill a gap, surveillance should be based on existing medical and laboratory systems, proven tools reinforced with the necessary human and financial resources. The performance of the public health surveillance system is ultimately predicated on trust on the part of participating clinicians, policymakers and international partners.</p></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"54 4","pages":"Article 104889"},"PeriodicalIF":3.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666991924000447/pdfft?md5=7a9eb9cd0bd479a075cef5f6c839cc49&pid=1-s2.0-S2666991924000447-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of a cluster of acute epiglottitis in Vendée, western France, October – December 2022 2022 年 10 月至 12 月法国西部旺代省急性会厌炎群集调查。

IF 3.5 4区医学

Infectious diseases now Pub Date : 2024-05-31 DOI: 10.1016/j.idnow.2024.104934

Gwénola Picard , Pascaline Loury , Ronan Ollivier , Thomas Guimard , Jean-Claude Lacherade , Yves-Marie Vandamme , Farah Boukraa , Lisa A. King

{"title":"Investigation of a cluster of acute epiglottitis in Vendée, western France, October – December 2022","authors":"Gwénola Picard , Pascaline Loury , Ronan Ollivier , Thomas Guimard , Jean-Claude Lacherade , Yves-Marie Vandamme , Farah Boukraa , Lisa A. King","doi":"10.1016/j.idnow.2024.104934","DOIUrl":"10.1016/j.idnow.2024.104934","url":null,"abstract":"<div><h3>Objectives</h3><p>In our investigation of an episode of clustered acute epiglottitis occurring in Vendée, western France, between October and December 2022, we described the reported cases and confirmed its unusual character at several geographic levels.</p></div><div><h3>Methods</h3><p>The investigation relied on three data sources: hospitalization and emergency department reports; national reference centre data; and data from the French syndromic surveillance system.</p></div><div><h3>Results</h3><p>The six patients were male, with an average age of 42 years [32–66]; all were hospitalized in an ICU, and one of them died. Documented risk factors for epiglottitis (active smoking, regular alcohol consumption, overweight) were present in the majority of cases. No causal pathogen was identified. Syndromic surveillance data confirmed increased acute epiglottitis at the local, regional and national levels.</p></div><div><h3>Conclusion</h3><p>We not only characterized the episode of serious clustered acute epiglottitis in Vendée, but also observed a nationwide increase in this pathology occurring concomitantly with increased circulation in France of streptococcus A.</p></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"54 5","pages":"Article 104934"},"PeriodicalIF":3.5,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666991924000988/pdfft?md5=cb0b28ac86976f52b209065a9d5bbe29&pid=1-s2.0-S2666991924000988-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0