{"title":"Mesothelioma carcinogenesis of chrysotile and forsterite compared and validated by intraperitoneal injection in rat.","authors":"Ayako Takata, Hiroshi Yamauchi, Kiyotsugu Yamashita, Masahito Aminaka, Toshiaki Hitomi, Tadao Toya, Norihiko Kohyama","doi":"10.2486/indhealth.2024-0025","DOIUrl":"10.2486/indhealth.2024-0025","url":null,"abstract":"<p><p>Asbestos, especially chrysotile, continues to be exposed to humans globally. Hence, it should be disposed properly to prevent asbestos-related diseases, including mesothelioma and lung cancer. This study aimed to verify whether forsterite, a heating product of chrysotile, can cause carcinogenicity, particularly mesothelioma. Forsterite (FO-1000) and enstatite (EN-1500) produced by heating chrysotile at 1,000°C and 1,500°C, respectively, were subjected. We injected 10 mg of chrysotile, FO-1000, or EN-1500 in rats intraperitoneally and observed the development of peritoneal mesothelioma until 24 months. The incidence of peritoneal mesothelioma in the chrysotile group was 91.2%, whereas in the FO-1000 and EN-1500 groups, peritoneal mesothelioma did not develop. Urinary 8-hydroxy-2'-deoxyguanosine and serum N-ERC/mesothelin concentrations significantly increased in the chrysotile group that developed peritoneal mesothelioma, while they only temporarily changed in the FO-1000 or EN-1500 groups during early treatment. Furthermore, there was a significant homozygous deletion of the CDKN2A/p16 gene in the chrysotile group compared to the control group, in contrast to no significant difference in the FO-1000 and EN-1500 groups. Therefore, this study provides clear evidence that forsterite is a nonmesothelioma carcinogen and suggests that forsterite and enstatite are sufficient substances for chrysotile detoxification.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":"14-28"},"PeriodicalIF":1.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11779520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2025-01-24Epub Date: 2024-05-20DOI: 10.2486/indhealth.2024-0027
Tianchang Ji, May Young Loh, Jan DE Jonge, Maria C W Peeters, Toon W Taris, Maureen F Dollard
{"title":"\"Are you feeling safe?\": an investigation of psychosocial safety climate in the relations of job characteristics and employee exhaustion and engagement.","authors":"Tianchang Ji, May Young Loh, Jan DE Jonge, Maria C W Peeters, Toon W Taris, Maureen F Dollard","doi":"10.2486/indhealth.2024-0027","DOIUrl":"10.2486/indhealth.2024-0027","url":null,"abstract":"<p><p>Psychosocial safety climate (PSC) is defined as the corporate climate in relation to employees' perceptions of organizational policies, procedures, and practices for the protection of employee psychosocial safety and well-being. The present study was based on the Demand-Induced Strain Compensation (DISC) Model and proposed that the interplay between identical job demands and resources would be conditioned by PSC. Particularly, high levels of PSC would enable employees to optimally perceive and utilize more job resources in dealing with corresponding job demands. A study was conducted among 406 Chinese workers from various occupational sectors. The findings of hierarchical regression analyses suggested that PSC a) mitigates the negative relation between emotional resources and exhaustion, b) enhances the positive relation between emotional resources and work engagement, and c) mitigates the negative relation between emotional demands and work engagement. We also found that PSC is a compensatory factor for low cognitive resources and demands encouraging high work engagement. Although we did not find the proposed three-way interactions, the present findings support the idea that high PSC is a fundamental contextual factor conducive to workers' health and well-being, especially in perceiving and obtaining emotional resources.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":"3-13"},"PeriodicalIF":1.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11779518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2025-01-23DOI: 10.2486/indhealth.2024-0160
Yu Min Lee, Jae Yoon Kim, Hyoungseob Yoo, Mo-Yeol Kang
{"title":"Association of workplace toilet access with urinary tract symptoms and productivity loss among female workers.","authors":"Yu Min Lee, Jae Yoon Kim, Hyoungseob Yoo, Mo-Yeol Kang","doi":"10.2486/indhealth.2024-0160","DOIUrl":"https://doi.org/10.2486/indhealth.2024-0160","url":null,"abstract":"<p><p>This study investigated workplace toilet access related to lower urinary tract symptoms (LUTS) among women in the Korean workforce. A cross-sectional survey was conducted to determine demographic characteristics, occupational risk factors, and urinary tract symptoms among employed Korean women. Occupational risk factors included two survey questions about access to toilets at work. LUTS were assessed using the overactive bladder symptom score (OABSS) and international consultation on incontinence questionnaire-urinary incontinence short form (ICIQ-SF). Health-related productivity losses (HRPL) were estimated using the work productivity and activity impairment questionnaire for urinary symptoms (WPAI-US). Multiple logistic regression was used to determine the association between workplace toilet access and LUTS. In addition, generalised linear regression analysis was performed to assess HRPL according to workplace toilet access. Of the 1057 participants, 260 (24.6%) and 294 (27.81%) had overactive bladder and urinary incontinence, respectively. More than 50% reported poor access to toilet. Multiple logistic regression analysis showed that the lower the access to toilets in the workplace, the higher the incidence of LUTS and the higher HRPL. In conclusion, restricted access to toilets at work are associated with poor urinary health and loss of productivity.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effective management for the duration and quality of working time.","authors":"Masaya Takahashi","doi":"10.2486/indhealth.63_100","DOIUrl":"10.2486/indhealth.63_100","url":null,"abstract":"","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":"63 1","pages":"1-2"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of different break patterns during driving on cardiovascular responses in male drivers.","authors":"Xinxin Liu, Hiroki Ikeda, Yuki Nishimura, Shun Matsumoto, Tomohide Kubo","doi":"10.2486/indhealth.2024-0144","DOIUrl":"https://doi.org/10.2486/indhealth.2024-0144","url":null,"abstract":"<p><p>We examined cardiovascular responses during driving and investigated the effects of different break patterns on these responses. Forty-seven males in their 40s and 50s participated, and the protocol included three driving sets with four break patterns. One driving set consisted of 1 hour of city driving and 1 hour of highway driving. The four break patterns were a 30-min lunch break (short/one: SO, n=12), a 60-minute lunch break (long/one: LO, n=12), a 10-min break and a 50-min lunch break (long/two: LT, n=12), and a 10-min break and a 20-min lunch break (short/two: ST, n=11). The results showed that the lunch break was significantly effective in moderating diastolic blood pressure, mean arterial pressure and heart rate for all conditions, but the long-break conditions (LO and LT) were also effective in moderating cardiac output and stroke volume. Additionally, for the same total break length, one longer break was more effective in moderating cardiovascular and subjective burden than two shorter breaks. The results of this study suggest that it is important for drivers to take a lunch break, especially a long break around an hour, to reduce cardiovascular and subjective burden during their shift.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors and their age differences associated with low back pain among Japanese workers: a cross-sectional study.","authors":"Koichi Sato, Kiyohide Tomooka, Setuko Sato, Takeshi Tanigawa","doi":"10.2486/indhealth.2024-0067","DOIUrl":"https://doi.org/10.2486/indhealth.2024-0067","url":null,"abstract":"<p><p>This study aimed to examine the factors and their age differences associated with low back pain (LBP), including lifestyle and psychosocial factors, among Japanese workers at a large company. The study population consisted of 25,610 workers (mean ± SD age, 44.7 ± 9.6 yr) who underwent annual health checkups and completed the Brief Job Stress Questionnaire (BJSQ) at a Japanese company in 2017. The self-administered questionnaire was used to assess gender, age, occupation, smoking status, exercise status, alcohol intake, job stress, and sleep duration. LBP presence was assessed using a part of the BJSQ. Multivariable-adjusted logistic regression analyses were performed to examine the factors associated with LBP according to age category. The prevalence of LBP in the study group was 23.3%. After stratification by age, overweight status and job stress were found to be significantly associated with LBP in all age groups. However, smoking status was significantly associated with LBP among individuals aged <40 yr (effect of interaction p=0.03) whereas exercise was significantly associated only among individuals aged ≥40 yr (effect of interaction p<0.01). This study shows that LBP factors may differ by age, highlighting the importance of age-appropriate measures for preventing LBP in workers.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2024-12-11DOI: 10.2486/indhealth.2024-0089
Idris Sula, Juliann Saquib, Abdulrahman Almazrou, Abdulrahman Farhat, Tarek Djoudjou, Abdulrahman Zakaria, Ibrahim Omar, Muhammad Lengga, Ali Aal Ibrahim, Mohammad Alfattal, Mohammed Alrabeei, Mohammed Albabakri, Ahmad Alshomar, Nazmus Saquib
{"title":"Work-related injuries and compliance with personal protective equipment among migrant workers in Al-Qassim, Saudi Arabia.","authors":"Idris Sula, Juliann Saquib, Abdulrahman Almazrou, Abdulrahman Farhat, Tarek Djoudjou, Abdulrahman Zakaria, Ibrahim Omar, Muhammad Lengga, Ali Aal Ibrahim, Mohammad Alfattal, Mohammed Alrabeei, Mohammed Albabakri, Ahmad Alshomar, Nazmus Saquib","doi":"10.2486/indhealth.2024-0089","DOIUrl":"https://doi.org/10.2486/indhealth.2024-0089","url":null,"abstract":"<p><p>Migrant workers constitute nearly one-third of Saudi Arabia's population, with a significant portion engaged in low-skilled manual labour. Limited data exists on work-related injuries and the use of personal protective equipment (PPE) among workers. The current cross-sectional survey focused on seven occupational groups, (i.e., auto-repair workers, city cleaners, construction workers, hairdressers, hospital cleaners, poultry factory workers, and restaurant workers) in the Al-Qassim region of Saudi Arabia. The sample of 2123 workers were predominantly men (85.3%) and from the Indian subcontinent (64.9%). Among the workers, 21.5% reported having one or more work-related injuries, with cuts (27%), slipping/falling (17%), and thermal injuries (9%) being the most common. Compliance with PPE varied across professions, with city cleaners (86.1%) and restaurant workers (85%) being the most compliant. The study highlights a concerning prevalence of injuries and insufficient PPE usage among migrant workers, emphasizing the need to enhance workplace safety.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between andropause symptoms and work functioning impairment: a cross-sectional study in two Japanese companies.","authors":"Makoto Okawara, Seiichiro Tateishi, Shigeo Horie, Toshiyuki Yasui, Yoshihisa Fujino","doi":"10.2486/indhealth.2024-0168","DOIUrl":"https://doi.org/10.2486/indhealth.2024-0168","url":null,"abstract":"<p><p>The study aimed to assess the relationship between andropause, or male menopause, and work functioning in aging Japanese male workers. A cross-sectional study was conducted on 561 male employees from two Japanese companies. We measured andropause symptoms using the Aging Male's Symptoms (AMS) scale, and work functioning impairment using the Work Functioning Impairment Scale (WFun). The data were analyzed using Poisson regression with robust variance to estimate the relationship between andropause severity and work functioning impairment. The findings indicated a significant association between severe symptoms of andropause and increased work functioning impairment among male workers. Higher AMS scores, reflecting more severe symptoms, correlated with greater work functioning impairment, particularly with regard to physical and psychological health issues, such as muscle weakness and depressive symptoms. This study highlights the need for workplace health programs that include middle-aged and older male workers to address and manage symptoms of andropause. Further, it emphasizes the importance of recognizing andropause as a significant health issue that can adversely affect work performance and productivity. Future studies should incorporate the measurement of testosterone to ensure the more accurate assessment of andropause and its impact on work functioning.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2024-11-26Epub Date: 2024-09-10DOI: 10.2486/indhealth.2024-0115
Mayumi Saiki, Wendie Robbins, Dante Anthony Tolentino, Paul M Macey, Akinori Nakata, Jian Li
{"title":"Associations of work-family conflict with changes in metabolic risk factors: a four-year longitudinal study.","authors":"Mayumi Saiki, Wendie Robbins, Dante Anthony Tolentino, Paul M Macey, Akinori Nakata, Jian Li","doi":"10.2486/indhealth.2024-0115","DOIUrl":"10.2486/indhealth.2024-0115","url":null,"abstract":"<p><p>Cardiovascular disease (CVD) is becoming prevalent among younger people who have dual roles at both work and home. A possible contributor to CVD is conflict between work and home life. Thus, this study investigated the impact of work-to-family conflict (WFC) and family-to-work conflict (FWC) on metabolic risk factors. We used longitudinal data with a 4-yr interval from the Midlife in Japan study. 152 participants who were employed at baseline without missing variables of interest were included. We assessed the associations of baseline WFC and FWC with changes in metabolic risk factors between baseline and follow-up using Generalized Estimating Equations. After adjusting for baseline sociodemographic, work and family-related, and lifestyle factors, the fully adjusted model showed WFC was significantly associated with changes in low-density lipoprotein cholesterol (LDL-C) and Total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio. However, FWC was not significantly associated with changes in any metabolic risk factors. Our findings indicated a significant impact of WFC on LDL-C and TC/HDL-C ratio but no significant impact of FWC on metabolic health. Since these metabolic risk factors cause CVD, understanding the physiological responses to occupational psychosocial stress could help create primary prevention interventions and assess their effects on workers' metabolic health.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":"367-376"},"PeriodicalIF":1.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2024-11-26Epub Date: 2024-05-10DOI: 10.2486/indhealth.2023-0135
Madeline Evans, Meagan E Crowther, Brandon W J Brown, Sian Wanstall, Tim Rayner, Andrew Vakulin, Robert J Adams, Amy C Reynolds
{"title":"Sleep disorder risk, perceived control over sleep, and mental health symptoms in paramedicine students.","authors":"Madeline Evans, Meagan E Crowther, Brandon W J Brown, Sian Wanstall, Tim Rayner, Andrew Vakulin, Robert J Adams, Amy C Reynolds","doi":"10.2486/indhealth.2023-0135","DOIUrl":"10.2486/indhealth.2023-0135","url":null,"abstract":"<p><p>Paramedics commonly experience both poor sleep and mental health symptoms. Clarifying whether sleep or mental health symptoms are a challenge prior to commencement of employment is important, as early prevention and intervention initiatives during training could support these workers. Paramedicine students (n=53) were included, with sleep disorder screening (obstructive sleep apnea, insomnia and restless legs syndrome), and mental health outcomes (depressive symptoms: Patient Health Questionnaire-9, and anxiety symptoms: General Anxiety Disorder-7). Data were analysed using robust regression models, adjusted for age, sex, and shift work status. Meeting criteria for a sleep disorder (n=21) was associated with higher scores for anxiety (8.2 [95% CI: 5.9-10.5] v 4.6, [3.4-5.8]) and depressive symptoms (11.1 [8.6-13.6] v 4.4 [3.1-5.7)] compared to those who did not meet the criteria for a sleep disorder (n=32). Depressive symptoms were lower in those with perceived control over sleep (5.2 [3.2-7.2] v 9.8 [7.7-11.8]). There was no interaction between sleep disorder risk and perceived control over sleep on mental health symptoms. Investigation and management of factors contributing to low perceived control over sleep, together with early screening and management of sleep disorders, are likely to be important priorities to support paramedic student wellbeing prior to commencing shift work.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":"408-416"},"PeriodicalIF":1.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}