{"title":"Evaluation of respiratory toxicity and peritoneal mesothelioma induced by heat-treated and milled amosite following intratracheal and intraperitoneal injection in rats.","authors":"Hiroshi Yamauchi, Ayako Takata, Kiyotsugu Yamashita, Masahito Aminaka, Toshiaki Hitomi, Norihiko Kohyama","doi":"10.2486/indhealth.2025-0210","DOIUrl":"10.2486/indhealth.2025-0210","url":null,"abstract":"<p><p>Amoste is highly carcinogenic, and its incomplete removal from the environment continues to pose significant health risks. High temperatures are known to alter the crystal structure of asbestos. In this study, we evaluated the carcinogenicity and respiratory toxicity of heat-treated amosite (AM-1000; heated at 1,000°C) and its milled derivative (AM-1000G; heat-treated at 1,000°C and milled), using untreated amosite as a positive control. Physicochemical analyses confirmed that AM-1000G predominantly consisted of non-asbestiform structures with an aspect ratio of less than 3. In a single intratracheal administration study in rats (2 mg; observation period up to 540 d), AM-1000G induced much less severe acute and chronic pulmonary inflammation than amosite or AM-1000 and did not cause fibrosis. No pulmonary adenoma, lung cancer, or pleural mesothelioma was observed in any group. Following intraperitoneal administration (10 mg; two-year observation period), peritoneal mesotheliomas developed in 56% (14/25) of rats in the amosite group, whereas only one (1/25) rat in the AM-1000 group developed mesotheliomas. In contrast, no peritoneal mesothelioma was observed in the AM-1000G group. This study demonstrated that AM-1000G is non-carcinogenic and exhibits markedly reduced acute and chronic respiratory toxicity. These findings provide the first scientific evidence supporting the feasibility of amosite detoxification through heat treatment, based on its biological evaluation.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":"64 5","pages":"421-438"},"PeriodicalIF":1.6,"publicationDate":"2026-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149030404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2026-09-20Epub Date: 2026-02-16DOI: 10.2486/indhealth.2025-0216
Mikiko Kawasaki, Akinori Nakata, Shuhei Izawa
{"title":"Association of effort-reward imbalance with fingernail cortisol levels in apparel manufacturing workers.","authors":"Mikiko Kawasaki, Akinori Nakata, Shuhei Izawa","doi":"10.2486/indhealth.2025-0216","DOIUrl":"10.2486/indhealth.2025-0216","url":null,"abstract":"<p><p>In this prospective cross-sectional epidemiological study, we aimed to investigate the relationship between psychosocial job-related stress (effort-reward imbalance [ERI]) and fingernail cortisol levels. In total, 136 daytime employees (109 women and 27 men; age 18-72 [38.9 ± 12.9] yr) at a school uniform sewing factory were recruited. Fingernail-based cortisol analysis was performed in September 2017 (Time 1, baseline) and December 2017 (Time 2). The participants completed a short version of the Japanese ERI questionnaire at baseline. Multiple linear regression analyses controlling for potential confounders revealed that the effort score was positively associated with cortisol levels at Time 1 (β=0.252, p=0.004) and Time 2 (β=0.188, p=0.048), whereas no significant associations were observed for reward or ERI ratio. These findings suggest that linking adverse psychological working conditions to stress-related disorders may be biologically plausible. This study also highlights the importance of evaluating specific components of psychosocial stress at work in relation to chronic biological stress markers to enhance understanding of stress-related health risks and inform effective occupational health interventions.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":"491-500"},"PeriodicalIF":1.6,"publicationDate":"2026-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2026-09-16DOI: 10.2486/indhealth.2026-0176
Young-Jae Kim, Ki-Youn Kim
{"title":"Assessment of carcinogenic, mutagenic, and reprotoxic (CMR) substance exposure levels outside supplied-air respirators during shipboard spray painting in confined spaces.","authors":"Young-Jae Kim, Ki-Youn Kim","doi":"10.2486/indhealth.2026-0176","DOIUrl":"https://doi.org/10.2486/indhealth.2026-0176","url":null,"abstract":"<p><p>Ship spray painting in confined shipboard spaces poses significant risks of chemical exposure, particularly to carcinogenic, mutagenic, and reprotoxic (CMR) substances. This case report documents occupational exposure levels to CMR substances during spray painting operations at five shipyard companies in South Korea. Sampling was conducted during active spray painting, excluding preparation time, at eight measurement sites involving 15 workers using three painting products. Sampling devices were placed outside the supplied-air respirator facepiece to assess actual environmental exposure levels using activated charcoal tubes and passive samplers. The Exposure Index for mixed organic solvents exceeded 1 at all sites. Several CMR substances-including 2-methoxyethanol, 2-ethoxyethanol, toluene, ethylbenzene, methyl isobutyl ketone, and cyclohexanone-were detected above their occupational exposure limits, with 2-methoxyethanol reaching up to 44 times its TWA. These findings highlight the high-risk nature of confined-space spray painting and underscore the need for stringent protective measures and further research on CMR substance exposure management in shipbuilding.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2026-09-15DOI: 10.2486/indhealth.2026-0064
Jiyoun Jung, Seong-Sik Cho, Jaesung Choi, May Young Loh, Mo-Yeol Kang
{"title":"Psychosocial work environment and fertility intention among wage workers: a cross-sectional analysis of the general working population in Korea.","authors":"Jiyoun Jung, Seong-Sik Cho, Jaesung Choi, May Young Loh, Mo-Yeol Kang","doi":"10.2486/indhealth.2026-0064","DOIUrl":"https://doi.org/10.2486/indhealth.2026-0064","url":null,"abstract":"<p><p>South Korea has the lowest total fertility rate globally, and policies focused on economic incentives have failed to reverse this trend. Workplace conditions may influence fertility decisions, yet the role of the work environment remains underexplored. We examined associations between psychosocial working conditions and fertility intention among Korean wage workers. This cross-sectional study used data from the sixth wave of the Korean Work, Sleep, and Health Study (2025), including 1,249 paid employees aged <50 yr. Fertility intention was assessed as a binary outcome. Occupational factors included working-time characteristics, employment stability, occupational stress domains, psychosocial safety climate (PSC), and the presence of an occupational safety and health organization. Logistic regression models estimated odds ratios, with adjustment for age, sex, marital status, educational attainment, and equivalised household income. Working hours, shift work, commuting time, and working-time autonomy were not significantly associated with fertility intention. In contrast, employment stability and the presence of an OSH organization were positively associated with fertility intention. PSC showed the most consistent association. Low social support, organizational justice, and inappropriate reward were also linked to lower fertility intention. Fertility intention appears to be shaped more by psychosocial and organizational factors than by objective working-time characteristics.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Industrial HealthPub Date : 2026-09-11DOI: 10.2486/indhealth.2026-0278
Andreas Tsounis
{"title":"Reply to \"Beyond individual perceptions of justice: contextualizing work engagement, burnout, and employee well-being\".","authors":"Andreas Tsounis","doi":"10.2486/indhealth.2026-0278","DOIUrl":"https://doi.org/10.2486/indhealth.2026-0278","url":null,"abstract":"","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adherence to the Japanese Food Guide and chronic insomnia among Japanese male truck drivers: a cross-sectional study.","authors":"Melanie Griffith-Quintyne, Takeichiro Tominaga, Kouta Takahashi, Junpei Koike, Kyoko Nomura","doi":"10.2486/indhealth.2026-0096","DOIUrl":"https://doi.org/10.2486/indhealth.2026-0096","url":null,"abstract":"<p><p>Chronic insomnia is common among truck drivers and is associated with an increased risk of road traffic accidents. However, evidence linking diet quality to insomnia in Japanese working populations remains limited. This cross-sectional study examined the association between adherence to the Japanese Food Guide (JFG) and chronic insomnia among 1,942 male Japanese truck drivers. Dietary intake was assessed using the Brief-type Diet History Questionnaire, and diet quality was evaluated using a modified JFG score. Chronic insomnia was defined according to ICSD-3. Chronic insomnia prevalence was 20.2%. In multivariable logistic regression analyses adjusting for sociodemographic, lifestyle, occupational and psychological factors, participants in the highest JFG adherence quartile had lower odds of chronic insomnia than those in the lowest quartile (OR 0.69, 95% CI 0.49-0.97, p=0.034). No significant associations were observed for the second or third quartiles, and the linear trend was not significant (p for trend=0.056). Psychological distress was the strongest factor associated with chronic insomnia, but no significant interaction with JFG adherence was observed. Greater adherence to the Japanese Food Guide remained independently associated with lower odds of chronic insomnia, suggesting that diet quality may complement workplace mental health strategies.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The eating habits and lifestyle habits of shift workers: findings from the 2018 National Health and Nutrition Survey, Japan.","authors":"Tomomi Yamazaki, Kazuko Ishikawa-Takata, Hidemi Takimoto","doi":"10.2486/indhealth.2026-0057","DOIUrl":"https://doi.org/10.2486/indhealth.2026-0057","url":null,"abstract":"<p><p>Shift work increases chronic disease risk, but specific contributing factors, such as diet and lifestyle remain unclear. We compared eating habits and lifestyle characteristics between male and female shift and daytime workers across a variety of occupations using data from the 2018 Japan National Health and Nutrition Survey (n=1,814). Our analysis focused on food intake, lifestyle characteristics, and considerations in food selection between shift and daytime workers. Both male and female shift workers consumed significantly less fish and shellfish and had a shorter sleep duration than daytime workers. Male shift workers were more likely to select food based on preference and convenience than male daytime workers. Female shift workers consumed less milk and dairy products, and were less likely to choose foods based on seasons and seasonality than female daytime workers. These findings suggest that both male and female shift workers should be encouraged to increase their intake of fish and shellfish, while prioritizing adequate sleep and dietary variety; additionally, female shift workers in particular should be advised to increase their consumption of milk and dairy products for maintaining health. Adopting these nutritional and lifestyle adjustments is essential for mitigating the long-term health risks associated with shift work.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Structural relationships between pain catastrophizing and pain self-efficacy in relation to pain experience and presenteeism: a cross-sectional analysis using path analysis.","authors":"Toshiki Kishimoto, Yoshinori Kitabatake, Miyuki Seki","doi":"10.2486/indhealth.2026-0006","DOIUrl":"10.2486/indhealth.2026-0006","url":null,"abstract":"<p><p>Presenteeism among workers with pain has been linked to various cognitive and psychological factors; however, their structural relationships remain insufficiently understood. This study examined the structural relationships among pain catastrophizing, pain self-efficacy, psychological distress, and presenteeism among workers experiencing pain that interfered with work or daily life. An internet-based survey was conducted among 700 Japanese workers aged 20-60 years, of whom 459 who reported pain interfering with work or daily life during the preceding month were included in the analysis. Pain self-efficacy, pain catastrophizing, psychological distress, and presenteeism were assessed using validated Japanese versions of standardized questionnaires. A hypothesized path model was tested using path analysis to evaluate model fit and structural associations. The results demonstrated good model fit. Pain self-efficacy was directly and indirectly associated with presenteeism, whereas pain catastrophizing was indirectly associated with presenteeism through psychological distress. Notably, pain self-efficacy was broadly associated with multiple factors, including pain catastrophizing and psychological distress, as well as presenteeism. Higher pain self-efficacy was associated with reduced presenteeism, with associations partly observed through pain catastrophizing and psychological distress. These findings suggest that pain self-efficacy may represent a promising focus for future interventions aimed at reducing presenteeism among workers experiencing pain.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148722149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Musculoskeletal health in Swiss bus drivers: findings from the TRAPHEAC study.","authors":"Dusan Petrovic, Viviane Fiona Mathilde Remy, Daniela Prozorovscaia, Thomas Charreau, Irina Guseva Canu","doi":"10.2486/indhealth.2026-0098","DOIUrl":"https://doi.org/10.2486/indhealth.2026-0098","url":null,"abstract":"<p><p>Professional bus drivers are exposed to occupational hazards leading to chronic disease, including musculoskeletal disorders and joint pain. Here, we investigated factors associated with joint pain among Swiss bus drivers. We used data from the Transport Personnel Health Cohort (TRAPHEAC-N=549), a Swiss bus driver cohort, and the Swiss Health Study (SHeS-N=1,364), a population-based study. Joint pain was assessed using the Nordic questionnaire. Exposures included vibrations, ergonomics, work organization, stress, BMI, smoking, and physical activity. Associations were analyzed using logistic regression and random forest models. Joint pain was prevalent in TRAPHEAC, especially in the neck (67%), lower-back (59%), shoulders (54%), and upper-back (45%). Comparatively, back pain prevalence in SHeS was 11% (odds-ratios comparing TRAPHEAC with SHeS: 1.89). Logistic regression showed associations between seat and floor vibrations with neck, upper-back, and elbows (odds-ratios 1.1-1.5), while stress was associated with joint pain across all regions. BMI and ergonomics were associated with selected pain locations. Random forest models, using permutation importance, identified stress (shoulder, upper-back, lower-back, and knee pain) with seat vibrations and ergonomics (neck and ankle pain), as the most influential predictors of joint pain. Despite modern infrastructure, joint pain remains prevalent among Swiss bus drivers, supporting prevention targeting biomechanical and psychosocial factors.</p>","PeriodicalId":13531,"journal":{"name":"Industrial Health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148701182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}