Indian journal of applied research最新文献

{"title":"RELATION OF SERUM TOTAL TESTOSTERONE WITH SYMPTOMATOLOGY, COMPLICATIONS AND SEVERITY OF CHRONIC LIVER DISEASE IN MALE CIRRHOTICS","authors":"Harleen Sood, Rupinderjeet Kaur, R. Garg, K. Shourya","doi":"10.36106/ijar/9300403","DOIUrl":"https://doi.org/10.36106/ijar/9300403","url":null,"abstract":"Background: It has been seen that Testosterone (T) levels are generally low in men with advanced liver disease and\u0000progressively fall with increasing severity of liver disease. This may lead to the development of various clinical sequelae\u0000of advanced liver disease and adverse outcomes. Objectives: The study was done with an objective to assess serum testosterone in liver cirrhosis\u0000and to determine the relation of serum testosterone with symptomatology, complications and severity of liver cirrhosis in male patients.\u0000Methods: The observational study was carried out in G.G.S. Medical College and Hospital, Faridkot (Punjab, India). One hundred males of age\u000020-70 years with ultrasonographically proven cirrhosis of liver were included in the study. Demographic and clinical details of the patients were\u0000noted in the pre-designed proforma. Levels of serum total testosterone were measured in every patient. Laboratory investigations and Ultrasound\u0000of abdomen (with liver elastography) for cirrhosis liver was done. The severity of the disease was assessed by CTP and MELD score. Results:\u0000Signicant negative correlation of serum total testosterone was seen with MELD score, total bilirubin, ALP. Non signicant mild positive\u0000correlation was seen between serum total testosterone with serum albumin levels, blood platelet count, serum sodium levels and AFP. We found\u0000signicant association of low Testosterone levels with high CTP (p=0.007) and high MELD scores (p=0.042). No signicant association of\u0000complications was found with low testosterone. No association was seen with age, etiological factors or symptomatology except presence of\u0000jaundice. Conclusion: We identify low testosterone as a novel biomarker that is associated with increased severity of cirrhosis liver in men. This\u0000study provides a strong rationale to conduct adequately powered interventional trials to determine whether testosterone therapy can improve\u0000survival and other outcomes in this population.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140792016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A STUDY ON HEAVY METAL CONTENT IN SINGHARA FLOUR IN INDIA","authors":"Ashish Mukherjee, Manvi Sharma, Anup K Senapati","doi":"10.36106/ijar/5410183","DOIUrl":"https://doi.org/10.36106/ijar/5410183","url":null,"abstract":"Singhara atta is an excellent source of good carbohydrate and energy boosting nutrients like iron, calcium, zinc and\u0000phosphorous. There are no reports regarding the level of heavy metal content in Singhara our. The objectives of this\u0000study was to determine the concentrations of lead (Pb) and copper (Cu) in Singhara our collected from various part of India. Out of 24 samples of\u0000Singhara our analysed, Lead (Pb) content ranged from 0.0638 ppm to 1.6929 ppm and Copper (Cu) from 0.0011 ppm to 6.1725 ppm. It was\u0000found that 16 samples contain Lead (Pb) and all the samples for copper are within the permissible limit as specied by FSSAI. It is found that\u0000concentration of Lead (Pb) and Copper (Cu) in all Singhara our samples collected from various regions of India is within the safe limits as\u0000prescribed by FSSAI.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140771204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HYPER IgE SYNDROME – A CASE REPORT.","authors":"Shaik Irfani, P. Bi","doi":"10.36106/ijar/7905386","DOIUrl":"https://doi.org/10.36106/ijar/7905386","url":null,"abstract":"Hyper IgE Syndrome is a group of primary immunodeciency\u0000disorders with overlapping and distinct immunologic and non -\u0000immunologic features . It has two types of presentations. Type 1 is an\u0000autosomal dominant disorder with STAT 3 mutation. Type 2 is an\u0000autosomal recessive type with DOCK 8 mutation.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140772075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A SILENT BITE : FACTOR XII DEFICIENCY UNMASKED IN THE WAKE OF A SNAKE ENCOUNTER","authors":"Srutdi Kamalam Natarajan, Sairaksha Sudhakar, Devasena Srinivasan","doi":"10.36106/ijar/9704330","DOIUrl":"https://doi.org/10.36106/ijar/9704330","url":null,"abstract":"Factor 12 or the Hageman factor plays an essential role in the initiation of the intrinsic or the contact pathway of\u0000coagulation. The activation of the pathway occurs either due to direct contact with a negatively charged surface like glass\u0000or kaolin or proteolytic activation through prekallikrein and kallikrein system. Activated partial thromboplastin time or aPTT clotting assay is the\u0000test which is used to evaluate the status of the intrinsic pathway. Factor 12 deciency is a rare genetic disorder which usually follows an autosomal\u0000recessive pattern of inheritance however an autosomal dominant inheritance has also been reported. There is no established data regarding the\u0000prevalence of Factor 12 deciency in the normal population. Based on a study conducted on 300 healthy blood donors, an estimated prevalence of\u00002.3% has been reported according to Halbmayer WM, et al. The incidence of the condition is about 1 in 1,000,000 individuals. In patients with a\u0000deciency of Factor 12, the aPTT is typically prolonged and there are no associated bleeding tendencies. More often there is an increased risk of\u0000arterial or venous thromboembolic events and the patient is usually asymptomatic according to Chaudhry LA, et al.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140779050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CONCEPT OF “VISANKRAMANA”- A COMPREHENSIVE REVIEW ON AYURVEDIC DISINFECTION","authors":"Archana Panchaxarimath","doi":"10.36106/ijar/4203602","DOIUrl":"https://doi.org/10.36106/ijar/4203602","url":null,"abstract":"Ayurveda the ancient science of life emphasizes on prevention of disease and maintenance of health. The personal\u0000hygiene plays a pivotal role in controlling the transmission of disease. The disease-causing microorganisms present in our\u0000environment and may cause infections. Visankramana (Disinfection) is the procedure explained in Ayurvedic classics to prevent the transmission\u0000of infectious diseases. Our ancient Acharya's emphasized the importance of disinfecting the room and articles used by the patients to prevent the\u0000communicability of infectious disease. Several traditional techniques such as Dhoopana and have been adopted in the fumigation process to\u0000minimize microbial load in the environment to non-pathogenic level. Surgical instruments can be disinfected by traditional methods like Payana,\u0000Dhoopana, Parisheka and Agnitapana etc. Similarly, there are various classical references for disinfection of air, water, and land. This suggests\u0000that there is lot scope for the researchers to explore and evaluate the efcacy of traditional methods of disinfection.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140766666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FLAP CAPILLARY BLOOD GLUCOSE MONITORING AS A PREDICTOR OF FLAP SURVIVAL IN LIMBERG FLAP FOR PILONIDAL SINUS SURGERY.","authors":"M. Muralidharan, S. Muthulakshmi, P. Sumitra, Arunshreenivas Arunshreenivas","doi":"10.36106/ijar/5901191","DOIUrl":"https://doi.org/10.36106/ijar/5901191","url":null,"abstract":"Background: Pilonidal sinus is treated with wide local excision and primary closure, which carries high recurrence,\u0000post-operative morbidity and cosmetic implications. In order to overcome that limberg transposition ap is done. Postoperative ap survival is crucial for proper healing. Hence there is a need for a tool to predict ap survival as earliest. Flap capillary blood glucose\u0000monitoring is such a tool which is, done as a clinical basic procedure, with no harm to patient or the ap. To prospectively validate ap Methods:\u0000capillary blood glucose monitoring serially, as an indicator to predict ap survival in limberg ap in pilonidal sinus surgery patients at\u0000Government medical college & ESI hospital-general surgery department. Conducted as a prospective cohort study among 30 patients who\u0000underwent wide local excision and limberg ap for pilonidal sinus in the Department of General Surgery, Government Medical College & ESI\u0000Hospital between June- 2021 to November- 2021. Estimated capillary blood glucose at the edge of ap 3mm away from incision site, using\u0000glucometer at 0, 6, 24- hours following surgery. Of the 30 patients who underwent limberg ap surge Results: ry, 1 patient developed\u0000postoperative ap necrosis due to venous thrombosis. 1 patient developed ap infection which was treated with appropriate antibiotics after\u0000culture and sensitivity and the ap survived. Rest of the 28 patients had healthy aps and uneventful postoperative period. Of the 30 patients who\u0000underwent limberg ap for pilonidal sinus 29 patients in whom the ap survived had ap glucose level more than 62mg/dl, in the rst 24 hours.\u0000Conclusion: Monitoring ap capillary blood glucose serially in postoperative period in order to identify the aps in risk, to start early goal\u0000directed therapy to improve ap survival and the patients can benet. This simple and cheap technique can be used for routine monitoring of\u0000Limberg aps along with the routine clinical evaluation.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140760699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A RARE CASE OF TESTICULAR SEMINOMA WITH RETROPERITONEAL NODAL AND PULMONARY METASTASIS IN A TERTIARY CARE HOSPITAL IN TRIPURA","authors":"Soumyabrata Debnath, Monali Debnath, P. Santoshi","doi":"10.36106/ijar/9204209","DOIUrl":"https://doi.org/10.36106/ijar/9204209","url":null,"abstract":"Testicular neoplasms account for 1% to 2% of all malignant neoplasms in men. Approximately 95% of testicular tumours\u0000are germ cell tumours in young men. Seminomas account for more than 50% of germ cell tumours. Early diagnosis of\u0000testicular cancer leads to proper management and improve the outcome by preservation of future fertility. Whereas ultrasonography (USG) helps\u0000in early detection of testicular tumour, advanced diagnostic modalities such as CT scan and MRI aids in tumour staging, detecting nodal and\u0000distant metastasis as well as in assessing treatment response. We report one case of testicular seminoma with retroperitoneal nodal and pulmonary\u0000metastasis in a 22year old male patient. Very few cases of seminoma with distant metastasis in a young male have been reported in the literature till\u0000date which makes our case a rare entity.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140777453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIABETIC FOOT WITH NECROTISING FASCIITIS IN A 31 YEAR OLD DIABETIC FEMALE - A CASE REPORT.","authors":"Shaik Fazila Banu, P. S. Raghuram","doi":"10.36106/ijar/7101729","DOIUrl":"https://doi.org/10.36106/ijar/7101729","url":null,"abstract":"INTRODUCTION\u0000Diabetic foot can be dened as an infection involving the foot due to chronic or acute injury to the soft tissues of the foot\u0000with evidence of pre existing sensory neuropathy, micro vasculopathy and immunodeciency.\u0000Angiopathy and neuropathy are relatively common complications of diabetes mellitus (DM), causing diabetic foot, which brings enormous social\u0000and economic pressure to the patients. Diabetic foot ulcers combined with necrotizing fasciitis has rapid onset, involves a wide range of lesions.\u0000Necrotizing fasciitis is a rapidly progressive life-threatening infection. The risk factors for necrotizing fasciitis are diabetes, immunosuppression,\u0000hypertension, chronic renal failure. It causes systemic toxemia, septic shock and multiple organ dysfunctions increasing the mortality rate to 15%\u0000to 35%.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140779511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NON RANDOMIZED ASSESSMENT IN CASES OF INGROWN TOENAILVANDENBOS PROCEDURE.","authors":"Anil Kumar Sharma, Pradeep Kumar Verma, Sheetanshu Gupta, Amit Singh","doi":"10.36106/ijar/1005002","DOIUrl":"https://doi.org/10.36106/ijar/1005002","url":null,"abstract":"Background: - This condition usually occurs in patients who have experienced long-term trauma, poor foot hygiene, and\u0000tight-tting shoes causing long-term compression in toes. The Vandenbos procedure involves excising the soft tissue\u0000surrounding the nail without damaging the nail. This study consists of prospective observational asse Method: - ssment in patients with the above\u0000condition using the Vandenbos procedure The analysis included 50 patients who completed 6 months of Result: - postoperative assessment. The\u0000ages ranged from 8 to 35 years (mean 21.5 years). The average time to return to school or work was 10 days and the time to be able to wear enclosed\u0000shoes was 31 days. Within the rst two months of surgery, 11 participants (22%) experienced one or more minor complications like bleeding,\u0000infection, and hyper-granulation. There were no recurrences. The Vandenbos procedure was recommended by 90 % of participants. Conclusion: -\u0000The Vandenbos procedure can produce no recurrence rates, high satisfaction, and overall good cosmetic results.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140782521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A DESCRIPTIVE STUDY TO ASSESS THE KNOWLEDGE REGARDING HOME MANAGEMENT OF DYSMENORRHEA AMONG NURSING STUDENTS OF NEMCARE INSTITUTE OF NURSING SCIENCES, MIRZA, KAMRUP(R), ASSAM.","authors":"Nibedita Boro, Arunima Roy, Dimpi Kalita, Bijumoni Deka","doi":"10.36106/ijar/2100102","DOIUrl":"https://doi.org/10.36106/ijar/2100102","url":null,"abstract":"Background of the study: Dysmenorrhea means painful menstruation. most of the adolescent girls and women suffers\u0000from dysmenorrhea every month. Treatment of dysmenorrhea includes analgesics and few home remedial measure to\u0000alleviate the pain. Measures under home remedies includes hot pad application, herbal tea, massage therapy with aromatic oils etc. Adequate\u0000knowledge &awareness regarding home management plays a crucial role in reducing menstrual cramps during periods. To assess the level Aim:\u0000of knowledge and association of knowledge regarding home management of dysmenorrhea with their demographic variables among the nursing\u0000students. Quantitative research approach, Descriptive Research Design was adopted in this study, th Methods: e samples were collected by using\u0000total enumerative sampling technique from 239 nursing students. Majority, 183(77%) have moderately Results: adequate knowledge followed\u0000by 44(18%) adequate and 12(5%) inadequate knowledge regarding home management of dysmenorrhea. The Conclusion: study shows that\u0000majority of the students have moderately adequate knowledge regarding home management of dysmenorrhea and there is no signicant\u0000association between knowledge and their demographic variables except there dietary pattern and source of information.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140794245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}