{"title":"Letter to Editor re:Comparison of DIPSS and other interventions in Budd-Chiari syndrome.","authors":"Motij Kumar Dalai, Deepak S, Sanjay Jagdish Chandnani","doi":"10.1007/s12664-025-01855-8","DOIUrl":"10.1007/s12664-025-01855-8","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"786-787"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Indocyanine green fluorescence cholangiography in laparoscopic cholecystectomy: Game changer or just an adjunct.","authors":"Harjeet Singh, Thakur Deen Yadav","doi":"10.1007/s12664-025-01907-z","DOIUrl":"10.1007/s12664-025-01907-z","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"625-626"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Short versus standard esophageal myotomy during peroral endoscopic myotomy for achalasia: A systematic review and meta-analysis of randomized controlled trials.","authors":"Zaheer Nabi, Jahnvi Dhar, Jayanta Samanta, Pradev Inavolu, Raghavender Puri, D Nageshwar Reddy","doi":"10.1007/s12664-025-01897-y","DOIUrl":"10.1007/s12664-025-01897-y","url":null,"abstract":"<p><strong>Background and aims: </strong>Peroral endoscopic myotomy (POEM) is an established treatment for achalasia. Conventionally, esophageal myotomy of 6-10 cm length is performed, although its necessity in type-I and type-II achalasia remains debatable. Recent studies suggest that a shorter myotomy may offer similar efficacy with potential advantages. We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing short vs. standard (long) esophageal myotomy during POEM in patients with type-I and type-II achalasia.</p><p><strong>Methods: </strong>This review was conducted in accordance with PRISMA 2020 guidelines and registered with PROSPERO (CRD42024611252). A systematic search of PubMed, Embase and Scopus was performed to identify RCTs comparing short and long esophageal myotomy during POEM. The primary outcome was clinical success at ≥ 1 year (Eckardt score ≤ 3). Secondary outcomes included procedure time, adverse events, post-POEM integrated relaxation pressure (IRP), barium column height and gastroesophageal reflux disease (GERD). Risk of bias was assessed using the Cochrane RoB 2.0 tool and the certainty of evidence was evaluated using the GRADE framework.</p><p><strong>Results: </strong>Four RCTs including 419 patients (short, n = 206; long, n = 213) were analyzed. Clinical success at one year was comparable between the two groups (OR 2.17; 95% CI = 0.76-6.23; p = 0.15; I2 = 12%). Procedure time was significantly shorter with short myotomy (MD - 17.69 min; p < 0.001). Rates of adverse events and physiological outcomes (IRP, barium retention) were similar. While overall GERD rates were comparable, esophageal acid exposure was significantly lower in the short myotomy group (OR 0.69; p = 0.04).</p><p><strong>Conclusion: </strong>Short esophageal myotomy is non-inferior to long myotomy in clinical efficacy with the added benefit of shorter procedure time and potentially reduced acid exposure. These findings support the use of short myotomy as a safe and efficient alternative in type-I and type-II achalasia.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"637-646"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145700826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to Editor reply: \"Comparison of EUS FNAC and EUS FNB in intra-abdominal masses\".","authors":"Motij Kumar Dalai, Deepak Sasikumar, Sanjay Jagdish Chandnani","doi":"10.1007/s12664-025-01814-3","DOIUrl":"10.1007/s12664-025-01814-3","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"784-785"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Masked hypertension in patients with irritable bowel syndrome: A direction worthy of in-depth study.","authors":"Ting-Ting Ji, Yi-Heng Yao, Liang Liu, Hai-Su Li","doi":"10.1007/s12664-025-01863-8","DOIUrl":"10.1007/s12664-025-01863-8","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"778-779"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelo Christopher, Srujan Lam Sharma, Pranay Gaikwad, Ajith John George, Cecil T Thomas, Emmanuel Lazarus
{"title":"Identification of vasculo-biliary anatomy using indocyanine green during laparoscopic cholecystectomy: A prospective observational study-the IVA green study.","authors":"Angelo Christopher, Srujan Lam Sharma, Pranay Gaikwad, Ajith John George, Cecil T Thomas, Emmanuel Lazarus","doi":"10.1007/s12664-025-01871-8","DOIUrl":"10.1007/s12664-025-01871-8","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study evaluated the feasibility and effectiveness of near-infrared fluorescence using indocyanine green (ICG) for intra-operative identification of cystic duct and artery anatomy, including aberrations, during laparoscopic cholecystectomy.</p><p><strong>Methods: </strong>A prospective observational non-blinding study was conducted from November 2019 to February 2023, enrolling 67 adult patients scheduled for laparoscopic cholecystectomy. Indocyanine green (0.2 mg/kg) was administered six to 10 hours before surgery. Visualization of the cystic duct, common bile duct (CBD) and cystic artery was assessed using near-infrared fluorescence imaging. Univariate and multivariate analysis was done to identify the correlation between demographic and clinical factors with the identification of the cystic duct, CBD and cystic artery. Univariate and multivariate analysis was done to identify the correlation between gender and body mass index (BMI) with the identification of the cystic duct, CBD and cystic artery.</p><p><strong>Results: </strong>The vasculo-biliary structures were visualized with ICG administration. The cystic duct was identified in 88%, the CBD in 92.6% and the cystic artery in 85% (Group-II variant was the commonest). Visualization of the cystic duct was significantly more difficult in male patients, while the visualization of the cystic artery was significantly reduced in patients with a > 25 kg/m<sup>2</sup>.</p><p><strong>Conclusions: </strong>Indocyanine green-based near-infrared fluorescence is a safe, feasible and effective tool for enhancing the visualization of vasculo-biliary anatomy during laparoscopic cholecystectomy. It aids in preventing bile duct injury and supports safe dissection, particularly in patients with normal BMI. While not a replacement for intra-operative cholangiography, ICG fluorescence is a promising adjunct.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"690-696"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145400652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pancreatic exocrine insufficiency beyond pancreatitis.","authors":"Neha Berry, Ajay Kumar","doi":"10.1007/s12664-025-01879-0","DOIUrl":"10.1007/s12664-025-01879-0","url":null,"abstract":"<p><p>Pancreatic exocrine insufficiency (PEI) occurs when the amount of digestive enzymes released from the pancreas in response to a meal is insufficient or the enzymes are prematurely inactivated, thus resulting in maldigestion. The chief reasons for PEI include loss of pancreatic parenchyma, obstruction of the main pancreatic duct, reduced stimulation and pancreatic enzyme inactivation. Loss of pancreatic parenchyma in chronic pancreatitis and after an episode of severe acute necrotizing pancreatitis are the most common causes for PEI. However, PEI is an important cause for malabsorption in many other diseases beyond pancreatitis. These include pancreatic tumors, pancreas resection, cystic fibrosis, diabetes and inflammatory bowel disease. Though the pancreas secretes lipase, amylase and proteases, which are all required for digestion, it is only lipase insufficiency that is clinically important. Fat maldigestion occurs when lipase secretion falls to below 10% of normal. This threshold is defined as severe PEI and is a definite indication for pancreatic enzyme replacement therapy (PERT). In this review, we shall discuss about conditions, other than pancreatitis, which cause PEI, and understand the possible mechanisms by which they cause PEI. We shall also discuss whether the addition of PERT will benefit patient management in such conditions.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"666-679"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145573520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}