{"title":"Reply to the letter \"Therapeutic plasma exchange in hepatitis A-related acute liver failure: Does study design influence interpretation?\"","authors":"Asisha M Janeela, Ashish Goel, C E Eapen","doi":"10.1007/s12664-026-02094-1","DOIUrl":"https://doi.org/10.1007/s12664-026-02094-1","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hepatocellular carcinoma with bile duct tumor thrombosis: An uncommon cause for obstructive jaundice.","authors":"Arshia Bhardwaj, Arshdeep Singh, Chandan Kakkar, Vandana Midha, Ajit Sood","doi":"10.1007/s12664-026-02100-6","DOIUrl":"https://doi.org/10.1007/s12664-026-02100-6","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Shahzil, Fariha Hasan, Ammad Javaid Chaudhary, Syeda Hafsa Qadri, Muhammad Saad Faisal, Anza Muhammad, Abdullah Ejaz, Shuhaib Ali, Rimmel Ali, Oasima Muner, Muhammad Ali Khaqan, Syed-Mohammed Jafri
{"title":"Outcomes of Clostridium difficile infection in liver transplant patients: A systematic review and meta-analysis.","authors":"Muhammad Shahzil, Fariha Hasan, Ammad Javaid Chaudhary, Syeda Hafsa Qadri, Muhammad Saad Faisal, Anza Muhammad, Abdullah Ejaz, Shuhaib Ali, Rimmel Ali, Oasima Muner, Muhammad Ali Khaqan, Syed-Mohammed Jafri","doi":"10.1007/s12664-026-02040-1","DOIUrl":"https://doi.org/10.1007/s12664-026-02040-1","url":null,"abstract":"<p><strong>Background: </strong>Clostridioides difficile infection (CDI) is a significant healthcare-associated complication, especially for liver transplant (LT) recipients who are at increased risk due to their immuno-suppressed status and antibiotic use. This systematic review and meta-analysis aimed at elucidating the outcomes of CDI in LT recipients.</p><p><strong>Methods: </strong>We adhered to PRISMA guidelines and searched databases including CENTRAL, PubMed, Embase and Scopus until December 2024. Studies included LT recipients with and without CDI. Outcomes were pooled using meta-analytic techniques with risk ratios (RR) for dichotomous data and mean differences for continuous data.</p><p><strong>Results: </strong>Among 10 included studies (1,216,500 LT recipients; 3.2% with CDI), the primary pooled analysis showed no significant difference in mortality (OR, 1.34; 95% CI, 0.38-4.72; I<sup>2</sup> = 100%). Sensitivity analyses excluding influential studies showed higher mortality in LT recipients with CDI (OR, 1.87; 95% CI, 1.45-2.41; I<sup>2</sup> = 43%). Length of stay was longer among LT recipients with CDI (mean difference, 6.00 days; 95% CI, 2.83-9.17; I<sup>2</sup> = 100%), with sensitivity analysis showing a mean difference of seven days after exclusion of one study (I<sup>2</sup> = 0%). Elevated model for end-stage liver disease (MELD) scores were significantly higher in CDI cases (mean difference, 2.77; 95% CI, 1.34-4.20), indicating higher disease severity at baseline. Proton pump inhibitor (PPI) use was not significant in the primary pooled analysis (OR, 2.18; 95% CI, 0.29-16.27; I<sup>2</sup> = 69%) but was significant after sensitivity analysis excluding one study (OR, 5.87; 95% CI, 2.65-13.03; I<sup>2</sup> = 0%).</p><p><strong>Conclusion: </strong>In addition to a significant association between PPI use and increased risk of CDI, CDI significantly affects mortality, duration of hospital stays and pre-operative MELD scores in LT recipients, underscoring its impact on post-operative outcomes.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Albumin-bilirubin grade and sarcopenia as predictors of prognosis in patients with unresectable intermediate and advanced-stage hepatocellular carcinoma\".","authors":"Abdul Basit Munir, Haider Imran, Nashmia Faraz","doi":"10.1007/s12664-026-02093-2","DOIUrl":"https://doi.org/10.1007/s12664-026-02093-2","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Himsikhar Khataniar, Hany Habib, Hussam Almasri, Rahul Karna, Stuart K Amateau
{"title":"Trends and geographic patterns of retractions in clinical gastrointestinal literature: A retrospective analysis of the retraction watch database.","authors":"Himsikhar Khataniar, Hany Habib, Hussam Almasri, Rahul Karna, Stuart K Amateau","doi":"10.1007/s12664-026-02058-5","DOIUrl":"https://doi.org/10.1007/s12664-026-02058-5","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149136433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fahri Yetişir, Oguzhan Özdemir, Ömer Kurt, Ramazan Tiken, Osman Yüksel
{"title":"Laparoscopic median arcuate ligament release: Outcomes of 59 cases.","authors":"Fahri Yetişir, Oguzhan Özdemir, Ömer Kurt, Ramazan Tiken, Osman Yüksel","doi":"10.1007/s12664-025-01825-0","DOIUrl":"10.1007/s12664-025-01825-0","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"932-934"},"PeriodicalIF":2.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahyaar Omouri-Kharashtomi, Mohammad Mohammadi, Iman Menbari Oskouie, Faraz Mahdizadeh, Amir Anushiravani
{"title":"Prognostic value of albumin-bilirubin grade in patients with pancreatic cancer: A systematic review and meta-analysis.","authors":"Mahyaar Omouri-Kharashtomi, Mohammad Mohammadi, Iman Menbari Oskouie, Faraz Mahdizadeh, Amir Anushiravani","doi":"10.1007/s12664-025-01945-7","DOIUrl":"10.1007/s12664-025-01945-7","url":null,"abstract":"<p><strong>Background: </strong>With a five-year survival rate near 10%, pancreatic cancer is among the cancers with poor survival. Understanding the prognostic factors provides clinical insights for better decision-making. This meta-analysis aims to assess the prognostic value of the albumin-bilirubin (ALBI) grade in patients with pancreatic cancer.</p><p><strong>Method: </strong>A comprehensive search using \"pancreatic cancer\" and \"ALBI grade\" as keywords was conducted on the PubMed, Web of Science, Embase and Scopus until August 14, 2025. Studies investigating the prognostic value of the ALBI grade in patients with pancreatic cancer were included. The prognostic value was assessed through the hazard ratio (HR) with a 95% confidence interval (95% CI). The meta-analysis was performed using R version 4.2.3.</p><p><strong>Results: </strong>The meta-analysis comprised six studies with 1665 patients for overall survival (OS) analysis and three studies with 936 patients for recurrence-free survival/disease-free survival (RFS/DFS). A higher ALBI grade was associated with decreased OS in patients with pancreatic cancer (HR = 2.14, 95% CI [1.53, 3.00]). A higher ALBI grade was associated with decreased RFS/DFS (HR = 2.39, 95% CI [1.02, 5.58]). A sub-group analysis based on ALBI grade revealed that no significant differences between different grading approaches (high vs. low, 2 vs. 1 and 3 vs. 1) were observed in predicting OS.</p><p><strong>Conclusion: </strong>A higher ALBI grade was significantly associated with decreased OS and RFS/DFS in patients with pancreatic cancer. The ALBI grade could be considered a reliable prognostic marker for clinical applications in patients with pancreatic cancer.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"816-827"},"PeriodicalIF":2.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changing etiology of acute pancreatitis in Kashmir: Implications for outcomes and healthcare utilization.","authors":"Tahir Majeed, Mehreen Syed Gurcoo, Sahil Hassan Sheikh","doi":"10.1007/s12664-026-01975-9","DOIUrl":"10.1007/s12664-026-01975-9","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"935-936"},"PeriodicalIF":2.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147283806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A typical case of IgG4 related sclerosing cholangitis.","authors":"Varsha Vishwakarma, Kaushal Madan, Pallavi Garg, Richa Bhargava","doi":"10.1007/s12664-024-01687-y","DOIUrl":"10.1007/s12664-024-01687-y","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"966-967"},"PeriodicalIF":2.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142345941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to Editor: Non-invasive liver fibrosis screening and referral patterns in women with dependence due to psychoactive substance use: A single-centre retrospective study.","authors":"Sana Banu Asari","doi":"10.1007/s12664-025-01955-5","DOIUrl":"10.1007/s12664-025-01955-5","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":"947-948"},"PeriodicalIF":2.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146179463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}