Indian Journal of Gastroenterology最新文献

{"title":"The right patient, the right time: Revisiting plasma exchange in HAV-related acute liver failure.","authors":"Jitendra Kumar Singh, Rakhi Maiwall","doi":"10.1007/s12664-026-02067-4","DOIUrl":"https://doi.org/10.1007/s12664-026-02067-4","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author's Reply: Reconsidering splenic stiffness measurement for non-invasive esophageal variceal screening in cirrhosis.","authors":"Abhishek Verma, Suprabhat Giri, Saroj Kanta Sahu, Subhadra Priyadarshini, Dibya Lochan Praharaj, Bipadabhanjan Mallick, Preetam Nath, Sarat Chandra Panigrahi, Manoj Kumar Sahu, Anil C Anand, Yogesh K Chawla, Subrat K Acharya","doi":"10.1007/s12664-026-02062-9","DOIUrl":"https://doi.org/10.1007/s12664-026-02062-9","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ALBI, EZ-ALBI and sarcopenia in hepatocellular carcinoma: Prognostic refinement or repackaging of established risk?","authors":"Prajna Anirvan","doi":"10.1007/s12664-026-02068-3","DOIUrl":"https://doi.org/10.1007/s12664-026-02068-3","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mild isolated hyperbilirubinemia in donors and short-term post-liver transplant survival in their recipients: A propensity-matched analysis.","authors":"Mohamad Jamalinia, Seyed Ali Malek-Hosseini, Saman Nikeghbalian, Siavash Gholami, Alireza Shamsaeefar, Hamed Nikoupour Deilami, Kourosh Kazemi, Kamran Bagheri Lankarani","doi":"10.1007/s12664-026-02059-4","DOIUrl":"https://doi.org/10.1007/s12664-026-02059-4","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148828037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased global burden of metabolic dysfunction-associated steatotic liver disease is also seen in women of reproductive age.","authors":"Waseem Amjad, Paul J Thuluvath","doi":"10.1007/s12664-026-02061-w","DOIUrl":"https://doi.org/10.1007/s12664-026-02061-w","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconsidering splenic stiffness measurement for non-invasive esophageal variceal screening in cirrhosis.","authors":"Wenjun Jiang","doi":"10.1007/s12664-026-02055-8","DOIUrl":"https://doi.org/10.1007/s12664-026-02055-8","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond a continental perspective: Geographic heterogeneity of Helicobacter pylori management in Africa.","authors":"Myriam Ayari, Sarrah Ben Azouz, Taieb Jomni","doi":"10.1007/s12664-026-02053-w","DOIUrl":"https://doi.org/10.1007/s12664-026-02053-w","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic plasma exchange in hepatitis A-related acute liver failure: Does study design influence interpretation?","authors":"Tamoghna Biswas, Bikrant Bihari Lal","doi":"10.1007/s12664-026-02060-x","DOIUrl":"https://doi.org/10.1007/s12664-026-02060-x","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of hepatic steatosis and fibrosis with microvascular complications among obese and non-obese individuals with T2D and MASLD.","authors":"Kanika Tyagi, Surya Prakash Bhatt, Irshad Ahmad Ansari, Shivam Pandey, Anoop Misra","doi":"10.1007/s12664-026-02037-w","DOIUrl":"https://doi.org/10.1007/s12664-026-02037-w","url":null,"abstract":"<p><strong>Background and objectives: </strong>Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized in non-obese individuals but remains poorly studied in people with type-2 diabetes (T2D), particularly in India. The study aimed at comparing hepatic steatosis, fibrosis and diabetes-related complications between non-obese (n, 150) and obese (n, 300) individuals with T2D.</p><p><strong>Methods: </strong>This was a comparative cross-sectional study in which the participants underwent clinical, biochemical and anthropometric assessments. Hepatic steatosis and fibrosis were evaluated using ultrasonography and transient elastography, with controlled attenuation parameter (CAP) and liver stiffness (kPa) measurements as key indicators. Diabetes-related complications were assessed using standardized protocols.</p><p><strong>Results: </strong>Non-obese individuals had higher retinopathy prevalence (18%) compared to obese individuals (8%), though this difference was non-significant (p = 0.141). Peripheral neuropathy was significantly more prevalent in non-obese (50.60%) vs. obese individuals (32%, p = 0.035), even after adjusting for confounders such as smoking and duration of diabetes. While CAP and kPa values were significantly higher in obese individuals, notable proportions of non-obese participants exhibited hepatic involvement-35% had CAP > 297 dB/m and 23% had liver stiffness ≥8.2 kPa. Among non-obese individuals, liver stiffness ≥9.7 kPa was associated with higher peripheral neuropathy. The FibroScan-AST score differed significantly between groups (p < 0.001). Non-obese participants had a higher proportion of low-risk scores (78% vs. 59.2%), but 22% still showed intermediate- or high-risk.</p><p><strong>Conclusions: </strong>Although obese individuals showed quantitatively higher CAP and liver stiffness values, non-obese individuals with T2D also exhibited clinically meaningful hepatic steatosis and fibrosis. Among the diabetes-related complications, peripheral neuropathy was the only complication that was more prevalent in the non-obese group.</p><p><strong>Clinical trial registry number: </strong>CTRI/2023/06/054199.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of the international bowel ultrasound segmental activity score for assessing disease activity in Crohn's disease.","authors":"Ashanpreet Kaur, Arshdeep Singh, Arshia Bhardwaj, Saurabh Singla, Suryaveer Singh, Vikram Narang, Ashutosh Bawa, Harmeet Kaur, Riya Sharma, Ramit Mahajan, Nishant Sharma, Kavita Saggar, Vandana Midha, Chandan Kakkar, Ajit Sood","doi":"10.1007/s12664-026-02041-0","DOIUrl":"https://doi.org/10.1007/s12664-026-02041-0","url":null,"abstract":"<p><strong>Background: </strong>Intestinal ultrasound (IUS) has emerged as a promising bedside tool for evaluating disease activity in Crohn's disease (CD), but real-world data using standardized ultrasound activity scores remain limited.</p><p><strong>Methods: </strong>In this cross-sectional observational study, patients with ileal, colonic or ileocolonic CD underwent IUS and ileocolonoscopy within a two-week interval. IUS findings were quantified using the International Bowel Ultrasound Segmental Activity Score (IBUS-SAS). Endoscopic activity was assessed using the Simple Endoscopic Score for Crohn's Disease (SES-CD). Diagnostic performance of IBUS-SAS for detecting endoscopic activity (SES-CD ≥ 3) was evaluated using receiver operating characteristic (ROC) analysis. Construct validity was assessed using Spearman correlation, discordance analyses and multi-variable logistic regression. Segment-level correlations and diagnostic accuracy were also examined.</p><p><strong>Results: </strong>Forty patients (median age 41 years; 18 [45%] female) with 160 bowel segments were analyzed. IBUS-SAS showed a moderate correlation with SES-CD (ρ = 0.45, p = 0.003) and FC (ρ = 0.35, p = 0.03. For detection of endoscopic activity, IBUS-SAS demonstrated an area under the ROC curve (AUC) of 0.75 (95% CI 0.52-0.97), numerically higher than FC, CRP and CDAI. At a cut-off of 24.0, IBUS-SAS achieved high sensitivity (96.7%) and negative predictive value (85.7%). Discordance analyses revealed progressively higher IBUS-SAS values with increasingly stringent composite definitions of disease activity. Segment-level analyses demonstrated stronger correlations and higher diagnostic accuracy in the transverse and left colon compared with the terminal ileum and ascending colon.</p><p><strong>Conclusions: </strong>The IBUS-SAS correlates with disease activity in CD and shows potential utility as a non-invasive rule-out and monitoring tool.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}