Indian Journal of Gastroenterology最新文献

{"title":"Prevalence of hepatitis B infection and its associated factors in rural South India: Response to correspondence.","authors":"Rajalatchumi Poorasamy, Sadhana Subramanian, Palanivel Chinnakali","doi":"10.1007/s12664-025-01878-1","DOIUrl":"https://doi.org/10.1007/s12664-025-01878-1","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of triglyceride-glucose index with disease severity in acute pancreatitis and its prognostic role: A prospective observational study.","authors":"Bobby Mitrolia, Rampartap Swami, Piyush Dadhich, Sunil K Dadhich, Sewaram Chaudhary, Sabir Hussain, Rajendra Bhati, Abhishek Yadav, Vivek Saini","doi":"10.1007/s12664-025-01849-6","DOIUrl":"https://doi.org/10.1007/s12664-025-01849-6","url":null,"abstract":"<p><strong>Background: </strong>Acute pancreatitis (AP) is a common gastrointestinal emergency with variable clinical course. Early identification of severe AP (SAP) is crucial for optimizing patient management. The triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, has been implicated in various metabolic disorders, but its role in predicting AP severity remains underexplored.</p><p><strong>Methods: </strong>In this single-center, prospective study, 138 patients diagnosed with AP were enrolled between January 2022 and December 2024. The severity of AP was classified as per the Revised Atlanta Classification. TyG index was calculated at admission and compared with established severity scores, including the computed tomography severity index (CTSI) and bedside index of severe acute pancreatitis (BISAP). Statistical analyses were performed to assess the correlation of TyG index with disease severity, hospital stay, intensive care unit (ICU) admission and mortality.</p><p><strong>Results: </strong>Among the enrolled patients, 17% developed SAP. The mean TyG index was significantly higher in the SAP group compared to the non-SAP group (5.01 ± 0.33 vs. 4.69 ± 0.22, p < 0.001). Higher TyG index values correlated with prolonged hospital stay (p = 0.009), increased ICU admissions (p < 0.001) and greater mortality (p = 0.004). The predictive accuracy of the TyG index for SAP, as assessed by the area under the curve (AUC), was 0.902, higher than BISAP 0.696 and CTSI 0.751.</p><p><strong>Conclusion: </strong>The TyG index is a simple and accessible biomarker that correlates with AP severity and prognosis. Its predictive value is higher than BISAP and CTSI.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to Editor reply: \"Comparison of EUS FNAC and EUS FNB in intra-abdominal masses\".","authors":"Motij Kumar Dalai, Deepak Sasikumar, Sanjay Jagdish Chandnani","doi":"10.1007/s12664-025-01814-3","DOIUrl":"https://doi.org/10.1007/s12664-025-01814-3","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transjugular intra-hepatic approach for portal vein stenting in post-inflammatory portal vein stenosis.","authors":"Kymentie Ferdinande, Stefano Groff, Alberto Zanetto, Francesco Labella, Michele Battistel, Giulio Barbiero, Marco Senzolo","doi":"10.1007/s12664-025-01873-6","DOIUrl":"https://doi.org/10.1007/s12664-025-01873-6","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic drainage in necrotizing pancreatitis: Is the four-week cut-off still relevant?","authors":"Guru Trikudanathan","doi":"10.1007/s12664-025-01870-9","DOIUrl":"https://doi.org/10.1007/s12664-025-01870-9","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-resolution anorectal manometry profile in patients with chronic constipation versus control.","authors":"Rahul Deshmukh, Shubham Jain, Saurabh Bansal, Anuraag Jena, Jay Chudasama, Sameet Patel, Qais Contractor, Asif Bagwan, Sanjay Chandnani, Pravin Rathi","doi":"10.1007/s12664-025-01830-3","DOIUrl":"https://doi.org/10.1007/s12664-025-01830-3","url":null,"abstract":"<p><strong>Background and aims: </strong>Studies comparing chronic constipation (CC) and asymptomatic subjects are lacking in our population. This study aimed to compare the high-resolution anorectal manometry (HRAM) profiles of patients with CC and healthy volunteers (HV), as well as patients with functional defecation disorders (FDD) and those without in the constipation group.</p><p><strong>Methods: </strong>This retrospective comparative study included patients with CC who underwent HRAM and a balloon expulsion test (BET). As historical controls, healthy volunteers were recruited. If both ARM and BET were abnormal, FDD was diagnosed using ROME-IV criteria.</p><p><strong>Results: </strong>Total 120 CC and 60 HV as controls were included. Maximum anal squeeze pressure (205 ± 62 vs. 170 ± 35 mmHg, p = 0.001), rectal sensations (1st sensation 49 vs. 40 ml, p = 0.024), desire to defecate (125 vs. 105 ml, p = 0.011) and maximum tolerable volume 171 vs. 150 ml, p = 0.018) were found to be significantly higher in CC patients as compared to controls. Median anal relaxation (15.5% [- 8.0 to 37.5] vs. 58.0% [34.0-77.0], p = 0.001), median defecation index (1.27 [0.88-1.74] vs. 2.00 [1.12-3.49], p = 0.001) and median recto-anal pressure gradient (17.50 [- 10.25 to 39.0] vs. 39.50 [7.50-69.0], p = 0.001) were significantly lower in CC patients. BET was not significant between CC and healthy volunteers (53% vs. 45%, p = 0.37). FDD was found in 57.5% of CC patients. Patients with FDD had higher anal residual pressure (95 ± 26 vs. 45 ± 21 mmHg, p = 0.001) and lower recto-anal pressure gradients than those without FDD (- 4.5 vs. 36 mmHg, p = 0.001). Rectal sensations were comparable in both FDD and non-FDD groups.</p><p><strong>Conclusion: </strong>The clinical and manometric profiles of CC and HV patients differed significantly. FDD and rectal hyposensitivity were more common in those with CC. Type-1 recto-anal dyssynergia was the most common FDD sub-type.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term outcomes and quality of life after repair of benign biliary stricture of post-cholecystectomy bile duct injury.","authors":"Jyoti Kharel, Thakur Deen Yadav, Rajesh Gupta, Harjeet Singh","doi":"10.1007/s12664-025-01832-1","DOIUrl":"https://doi.org/10.1007/s12664-025-01832-1","url":null,"abstract":"<p><strong>Introduction: </strong>Bile duct injury (BDI) is a potentially devastating complication of cholecystectomy. Although the repair may be successful, patients often experience a decline in their quality of life (QoL). However, there is a paucity of data regarding the factors influencing long-term outcomes and QOL in these patients.</p><p><strong>Methods: </strong>Patients who underwent benign biliary stricture (BBS) repair with at least three years of follow-up were assessed for inclusion in the study. Long-term outcomes were assessed with MacDonald Grading. QOL assessed using the SF-36 questionnaire, with a control group of patients who had uncomplicated laparoscopic cholecystectomy (LC).</p><p><strong>Results: </strong>Of 156 patients screened, 41 were included in the study, with a median follow-up duration of five (IQR 4.8) years. Successful long-term outcomes with MacDonald outcome grade A were observed in 28 (68.3%) patients, 12 (29.2%) patients had grade B and one (2.4%) had grade-D outcomes. External biliary fistula at the time of repair had grade-D outcome in one patient (14.2%) and grades B and A in three (42.9%) patients each. The higher strictures (types IV and V) were associated with higher MacDonald grade-B outcomes compared to types I-III strictures (7 [53.8%] vs. 5 [17.9%]) , whereas lower strictures were more likely to have grade-A outcomes as compared to higher strictures (22 [78.6%] vs. 6 [46.2%] [p = 0.044]). Patients with BDI repair reported significantly lower scores in all eight SF-36 domains compared to controls (p < 0.05).</p><p><strong>Conclusion: </strong>The long-term outcomes of delayed BBS repair are favorable in high-volume center. Despite the acceptable post operative clinical outcomes, the long-term QOL remains compromised after BBS repairs.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updates in the endoscopic management of colorectal polyps.","authors":"Clarence Kerrison, Nicholas G Burgess","doi":"10.1007/s12664-025-01838-9","DOIUrl":"https://doi.org/10.1007/s12664-025-01838-9","url":null,"abstract":"<p><p>Endoscopic resection of pre-malignant polyps remains a cornerstone of colorectal cancer prevention. This review provides an evidence-based analysis of the current approaches to endoscopic colorectal polyp management. Cold snare resection is recommended for small and diminutive polyps. Sessile serrated lesions are safely and efficiently removed using cold snare with or without sub-mucosal lift. For large non-pedunculated colorectal polyps (LNPCPs), snare tip soft coagulation of the resection margins reduces recurrence, post-resection clip closure of proximal colon lesions prevents post-endoscopic mucosal resection (EMR) bleeding and early recognition of deep mural injury (DMI) using the Sydney DMI Classification guides intervention and prevents delayed perforation. Cold-forceps avulsion with adjuvant snare tip soft coagulation (CAST) is an effective tool for managing residual or recurrent adenoma. Endoscopic sub-mucosal dissection (ESD) is recommended for selected high-risk LNPCPs based on location and endoscopic optical assessment. This comprehensive review synthesises these points based on current evidence and provides practical guidance for endoscopists, aimed at improving resection of colorectal polyps to enhance patient outcomes and safety.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Image-enhanced endoscopy in upper GI tract: State-of-the-art review.","authors":"Zaheer Nabi, Sonmoon Mohapatra, Noriya Uedo, Ashutosh Mohapatra, Pradev Inavolu, Hardik Rughwani, Mohan Ramchandani, D Nageshwar Reddy","doi":"10.1007/s12664-025-01850-z","DOIUrl":"https://doi.org/10.1007/s12664-025-01850-z","url":null,"abstract":"<p><p>Early and accurate identification of upper gastrointestinal (GI) malignancies remains a cornerstone for improving clinical outcomes. Conventional white light endoscopy, although the standard diagnostic modality, often fails to detect subtle premalignant and early neoplastic changes. Image-enhanced endoscopy (IEE) addresses these limitations by improving visualization of surface structures and vascular patterns. Despite its proven diagnostic value, IEE remains underutilized in resource-limited settings, largely due to lack of training and standardization. Adoption of structured training programs and digital learning tools could help bridge these gaps and enhance the detection of early GI neoplasms. This comprehensive review outlines the clinical utility of IEE in upper GI endoscopy, with a particular focus on narrow band imaging. Practical tips for usage are provided on equipment selection, procedural preparation and standardized examination techniques such as the Systematic Screening Protocol for the Stomach (SSS). Pre-medications, use of soft black hoods and anti-peristaltic agents are highlighted as critical adjuncts for optimizing visualization.</p>","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition in achalasia cardia-A neglected frontier.","authors":"Urvashi Rana, Harshal S Mandavdhare","doi":"10.1007/s12664-025-01866-5","DOIUrl":"https://doi.org/10.1007/s12664-025-01866-5","url":null,"abstract":"","PeriodicalId":13404,"journal":{"name":"Indian Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}