IET nanobiotechnology最新文献_第8页

Preparation and characterisation of polycaprolactone–fibroin nanofibrous scaffolds containing allicin 蒜素聚己内酯-丝素纳米纤维支架的制备与表征

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-08-05 DOI: 10.1049/nbt2.12092

Bita Mollaghadimi

{"title":"Preparation and characterisation of polycaprolactone–fibroin nanofibrous scaffolds containing allicin","authors":"Bita Mollaghadimi","doi":"10.1049/nbt2.12092","DOIUrl":"10.1049/nbt2.12092","url":null,"abstract":"Polycaprolactone (PCL) and silk fibroin are used to make nanofiber wound dressings, and then allicin is added to PCL and silk fibroin to expand antibacterial properties. The polymer solutions are subjected to various electrospinning parameters, and allicin-containing and non-allicin fibres are prepared. Fibres are examined by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), contact angle analysis, mechanical testing, bacterial culture, and 3-(4 5-dimethylthiazol-2-yl)-2 5-diphenyltetrazolium bromide (MTT). The SEM results show that the addition of fibroin and allicin at a constant voltage provides a direct relationship between the distance and the diameter of the fibres. Also, the total variation algorithm is used for denoising the signal of FTIR that the results confirm the functional groups present in the fibres. Furthermore, the contact angle test for allicin-free fibres shows that the contact angle of these fibres is 133.3° that decreases to 85.5° by adding allicin to the structure. Moreover, the tensile test of allicin-free fibres shows that Young's modulus of these fibres is 2.06 MPa, while the value increases to 5.12 MPa with the addition of allicin to the structure and at the end of the bacterial culture test, a growth inhibition zone is seen after 17 and 24 h. According to the obtained results, these fibres have the potential to be used in burn applications.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"16 7-8","pages":"239-249"},"PeriodicalIF":2.3,"publicationDate":"2022-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/21/5f/NBT2-16-239.PMC9469789.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40683326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Green biosynthesis of magnetic iron oxide nanoparticles using Mentha longifolia for imatinib mesylate delivery 绿色生物合成磁性氧化铁纳米颗粒的薄荷甲磺酸伊马替尼递送

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-06-30 DOI: 10.1049/nbt2.12090

Bahareh Naeimipour, Elham Moniri, Ali Vaziri Yazdi, Raheleh Safaeijavan, Hossein Faraji

{"title":"Green biosynthesis of magnetic iron oxide nanoparticles using Mentha longifolia for imatinib mesylate delivery","authors":"Bahareh Naeimipour, Elham Moniri, Ali Vaziri Yazdi, Raheleh Safaeijavan, Hossein Faraji","doi":"10.1049/nbt2.12090","DOIUrl":"10.1049/nbt2.12090","url":null,"abstract":"In this work, the rapid, facile, and eco-friendly green process was introduced in the preparation of β-cyclodextrin/magnetic iron oxide nanoparticles by using the aqueous Mentha longifolia extracts of Mentha longifolia. The obtained nanoparticles were characterised by Fourier transform infrared spectroscopy, x-ray powder diffraction, field emission scanning electron microscope, and thermogravimetric analysis. Also, effective factors on the synthesis of magnetic nanocomposites including temperature, concentration of the Mentha longifolia extract, and concentration of FeSO4 solution were optimised by Taguchi design. Moreover, important effective parameters on the adsorption efficiency; such as adsorbent dosage, pH, contact time, and temperature were investigated. The prepared magnetic nanocomposite was applied as a nanocarrier for imatinib mesylate delivery. In vitro studies confirmed imatinib mesylate release over 6 h. The nanocarrier showed pH-dependent imatinib mesylate release with higher drug release at simulated cancer fluid (pH = 5.6) compared to neural fluid (pH = 7.4). Moreover, the sorption isotherms and kinetics for the magnetic nanocomposite were fitted into Langmuir and pseudo-second order models, respectively. Based on the thermodynamic results, the adsorption of imatinib mesylate onto the nanoadsorbent was found to be spontaneous and exothermic.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"16 6","pages":"225-237"},"PeriodicalIF":2.3,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40411319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti. 紫叶树和绿色纳米银对登革热媒介蚊子的毒性及其对埃及伊蚊基因组DNA的影响。

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-06-01 DOI: 10.1049/nbt2.12082

Al Thabiani Aziz

{"title":"Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti.","authors":"Al Thabiani Aziz","doi":"10.1049/nbt2.12082","DOIUrl":"https://doi.org/10.1049/nbt2.12082","url":null,"abstract":"Marine seaweeds are known to have a potential role against microbial and pesticidal activities. Ulva lactuca, a green macroalgae extract analysed through gas chromatography mass spectrometry reveals 31 compounds. Resistance of mosquito vectors to synthetic insecticides remains a major problem. Discovering and applying natural agents to act against disease vectors is challenging. The activities of the extract and nano-fabricated green synthesised silver nanoparticles were checked for use against Aedes aegypti and Culex pipiens. The crude extract and synthesised silver nanoparticles exhibited a notable larvicidal effect, and very effective inhibition of pupal and adult emergence. Inhibition of adult emergence of Ae.aegypti was 97.7% and in Cu.pipiens, it was 93.3%. Our genotypic study of Deoxyribonucleic acid from treated larvae utilising random primers MA-09, MA-12 and MA-26 revealed damaged nucleotide sequences when compared with the controls. The antimicrobial activity of both the extract and green synthesised nanomaterials showed prominent activity against pathogenic drug resistant bacteria. Our results contribute to further development of eco-friendly insecticides with lower cost of preparation. This could further contribute to further research helping future generations to be free from these deadly disease-causing vectors and pathogenic microbes.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"16 4","pages":"145-157"},"PeriodicalIF":2.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10249556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Mathematical model and nanoindentation properties of the claws of Cyrtotrachelus buqueti Guer (Coleoptera: Curculionidae) 小圆蝽爪爪的数学模型及纳米压痕特性(鞘翅目:圆蝽科)

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-05-26 DOI: 10.1049/nbt2.12089

Longhai Li, Wei Sun, Ce Guo, Huafeng Guo, Liu Lili, Ping Yu

{"title":"Mathematical model and nanoindentation properties of the claws of Cyrtotrachelus buqueti Guer (Coleoptera: Curculionidae)","authors":"Longhai Li, Wei Sun, Ce Guo, Huafeng Guo, Liu Lili, Ping Yu","doi":"10.1049/nbt2.12089","DOIUrl":"10.1049/nbt2.12089","url":null,"abstract":"Scanning electron microscopy (SEM) was used to observe the macroscopic, microscopic, and cross-sectional structures of the claws of Cyrtotrachelus buqueti Guer (Coleoptera: Curculionidae), and a mathematical model of a claw was used to investigate the structure–function relationships. To improve the quality of the SEM images, a non-local means (NLM) algorithm and an improved NLM algorithm were applied. After comparison and analysis of five classical edge-detection algorithms, the boundaries of the structural features of the claw were extracted based on a B-spline wavelet algorithm, and the results showed that the variable curvature of the beetle claw enhances its adhesion force and improves its strength. Adhesion models of the claw were established, and the mechanical properties of its biomaterials were measured using nanoindentation. Considering that the presence of water can affect the hardness and Young's modulus, both ‘dry’ and ‘wet’ samples were examined. For the dry samples, the hardness and Young's modulus were 0.197 ± 0.074 GPa and 1.105 ± 0.197 GPa, respectively, whereas the respective values for the wet samples were both lower at 0.071 ± 0.030 GPa and 0.693 ± 0.163 GPa. This study provides data that can inform the design of climbing robots.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"16 6","pages":"211-224"},"PeriodicalIF":2.3,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/nbt2.12089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44958724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Investigating preparation and characterisation of diphtheria toxoid-loaded on sodium alginate nanoparticles 藻酸钠纳米粒子负载白喉类毒素的制备及性质研究

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-05-24 DOI: 10.1049/nbt2.12088

Samira Aghamiri, Mojtaba Noofeli, Parvaneh Saffarian, Zahra Salehi Najafabadi, Hamid Reza Goudarzi

{"title":"Investigating preparation and characterisation of diphtheria toxoid-loaded on sodium alginate nanoparticles","authors":"Samira Aghamiri, Mojtaba Noofeli, Parvaneh Saffarian, Zahra Salehi Najafabadi, Hamid Reza Goudarzi","doi":"10.1049/nbt2.12088","DOIUrl":"10.1049/nbt2.12088","url":null,"abstract":"This paper aims to investigate the preparation and characterisation of the alginate nanoparticles (NPs) as antigen delivery system loaded by diphtheria toxoid (DT). For this purpose, both the loading capacity (LC) and Loading efficiency (LE) of the alginate NPs burdened by DT are evaluated. Moreover, the effects of different concentrations of sodium alginate and calcium chloride on the NPs physicochemical characteristics are surveyed in addition to other physical conditions such as homogenization time and rate. To do so, the NPs are characterised using particle size and distribution, zeta potential, scanning electron microscopy, encapsulation efficiency, in vitro release study and FT-IR spectroscopy. Subsequently, the effects of homogenization time and rate on the NPs are assessed. At the meantime, the NPs LC and efficiency in several DT concentrations are estimated. The average size of the NPs was 400.7 and 276.6 nm for unloaded and DT loaded, respectively. According to the obtained results, the zeta potential of the blank and DT loaded NPs are estimated as −23.7 mV and −21.2 mV, respectively. Whereas, the LC and LE were >80% and >90%, in that order. Furthermore, 95% of the releasing DT loaded NPs occurs at 140 h in the sustained mode without any bursting release. It can be concluded that the features of NPs such as morphology and particle size are strongly depended on the calcium chloride, sodium alginate concentrations and physicochemical conditions in the NPs formation process. In addition, appropriate concentrations of the sodium alginate and calcium ions would lead to obtaining the desirable NPs formation associated with the advantageous LE, LC (over 80%) and sustained in vitro release profile. Ultimately, the proposed NPs can be employed in vaccine formulation for the targeted delivery, controlled and slow antigen release associated with the improved antigen stability.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"16 5","pages":"199-209"},"PeriodicalIF":2.3,"publicationDate":"2022-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/nbt2.12088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47319247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Retraction 收缩

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-05-08 DOI: 10.1049/nbt2.12087

引用次数: 0

Nanocomposite of electrochemically reduced graphene oxide and gold nanourchins for electrochemical DNA detection 电化学还原氧化石墨烯和金纳米海胆的纳米复合物用于电化学DNA检测

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-04-20 DOI: 10.1049/nbt2.12086

Mostafa Azimzadeh, Zahra Aghili, Behrooz Jannat, Saeid Jafari, Saeed Rafizadeh Tafti, Navid Nasirizadeh

引用次数: 2

Medicinal plants mediated the green synthesis of silver nanoparticles and their biomedical applications 药用植物介导的纳米银绿色合成及其生物医学应用

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-04-15 DOI: 10.1049/nbt2.12078

Haajira Beevi Habeeb Rahuman, Ranjithkumar Dhandapani, Santhoshini Narayanan, Velmurugan Palanivel, R. Paramasivam, Ramalakshmi Subbarayalu, Sathiamoorthi Thangavelu, S. Muthupandian

{"title":"Medicinal plants mediated the green synthesis of silver nanoparticles and their biomedical applications","authors":"Haajira Beevi Habeeb Rahuman, Ranjithkumar Dhandapani, Santhoshini Narayanan, Velmurugan Palanivel, R. Paramasivam, Ramalakshmi Subbarayalu, Sathiamoorthi Thangavelu, S. Muthupandian","doi":"10.1049/nbt2.12078","DOIUrl":"https://doi.org/10.1049/nbt2.12078","url":null,"abstract":"Abstract The alarming effect of antibiotic resistance prompted the search for alternative medicine to resolve the microbial resistance conflict. Over the last two decades, scientists have become increasingly interested in metallic nanoparticles to discover their new dimensions. Green nano synthesis is a rapidly expanding field of interest in nanotechnology due to its feasibility, low toxicity, eco‐friendly nature, and long‐term viability. Some plants have long been used in medicine because they contain a variety of bioactive compounds. Silver has long been known for its antibacterial properties. Silver nanoparticles have taken a special place among other metal nanoparticles. Silver nanotechnology has a big impact on medical applications like bio‐coating, novel antimicrobial agents, and drug delivery systems. This review aims to provide a comprehensive understanding of the pharmaceutical qualities of medicinal plants, as well as a convenient guideline for plant‐based silver nanoparticles and their antimicrobial activity.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"16 1","pages":"115 - 144"},"PeriodicalIF":2.3,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48770701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 63

Diverse biotechnological applications of multifunctional titanium dioxide nanoparticles: An up-to-date review 多功能二氧化钛纳米颗粒的多种生物技术应用:最新综述

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-04-12 DOI: 10.1049/nbt2.12085

Rabia Javed, Noor ul Ain, Ayesha Gul, Muhammad Arslan Ahmad, Weihong Guo, Qiang Ao, Shen Tian

{"title":"Diverse biotechnological applications of multifunctional titanium dioxide nanoparticles: An up-to-date review","authors":"Rabia Javed, Noor ul Ain, Ayesha Gul, Muhammad Arslan Ahmad, Weihong Guo, Qiang Ao, Shen Tian","doi":"10.1049/nbt2.12085","DOIUrl":"10.1049/nbt2.12085","url":null,"abstract":"Titanium dioxide (TiO2) nanoparticles (NPs) are one of the topmost widely used metallic oxide nanoparticles. Whether present in naked form or doped with metals or polymers, TiO2 NPs perform immensely important functions. However, the alteration in size and shape by doping results in improving the physical, chemical, and biological behaviour of TiO2 NPs. Hence, the differential effects of various TiO2 nanostructures including nanoflakes, nanoflowers, and nanotubes in various domains of biotechnology have been elucidated by researchers. Recently, the exponential growth of research activities regarding TiO2 NPs has been observed owing to their chemical stability, low toxicity, and multifaceted properties. Because of their enormous abundance, plants, humans, and environment are inevitably exposed to TiO2 NPs. These NPs play a significant role in improving agricultural attributes, removing environmental pollution, and upgrading the domain of nanomedicine. Therefore, the currently ongoing studies about the employment of TiO2 NPs in enhancement of different aspects of agriculture, environment, and medicine have been extensively discussed in this review.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"16 5","pages":"171-189"},"PeriodicalIF":2.3,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ietresearch.onlinelibrary.wiley.com/doi/epdf/10.1049/nbt2.12085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45130538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Rheological properties of wood/bacterial cellulose and chitin nano‐hydrogels as a function of concentration and their nano‐films properties 木材/细菌纤维素和几丁质纳米水凝胶的流变性能随浓度的变化及其纳米膜特性

IF 2.3 4区工程技术

IET nanobiotechnology Pub Date : 2022-04-04 DOI: 10.1049/nbt2.12083

Hesamoddin Jannatamani, A. Motamedzadegan, M. Farsi, H. Yousefi

{"title":"Rheological properties of wood/bacterial cellulose and chitin nano‐hydrogels as a function of concentration and their nano‐films properties","authors":"Hesamoddin Jannatamani, A. Motamedzadegan, M. Farsi, H. Yousefi","doi":"10.1049/nbt2.12083","DOIUrl":"https://doi.org/10.1049/nbt2.12083","url":null,"abstract":"Abstract In this study, rheological properties of the Wood Cellulose NanoFibers (WCNF), Bacterial Cellulose NanoFibers (BCNF), and Chitin NanoFibers (ChNF) as well as physical properties of films prepared from each nano‐hydrogel were investigated. Each nano‐hydrogel was prepared in 2 concentrations of 0.5 and 1 wt% for rheological study. Rheological properties were measured using a rotational rheometer. The flow behaviour data were fitted with rheological models. Apparent viscosity was higher in higher concentrations of nano‐hydrogels. Herschel‐Bulkley model was the best model for flow behaviour data fitting. BCNF nano‐hydrogels had the highest hysteresis loop while WCNF nano‐hydrogels had the best structure recovery and lowest hysteresis loop. At LVE (Linear Viscoelastic Region), G′ (storage modulus) and G″ (loss modulus) had a constant value, but as strain increased their values decreased. Storage modulus was found to be greater than loss modulus in all samples during frequency sweep test. BCNF nano‐hydrogel showed the lowest frequency dependency. Chitin nanofilms had the highest elongation and stress value.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"16 1","pages":"158 - 169"},"PeriodicalIF":2.3,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49143140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4