IET nanobiotechnology最新文献_第6页

Corrigendum to “Chitosan nanoparticle loaded by epidermal growth factor as a potential protein carrier for wound healing: In vitro and in vivo studies” “表皮生长因子负载壳聚糖纳米颗粒作为伤口愈合的潜在蛋白质载体：体外和体内研究”的勘误表

IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2025-04-18 DOI: 10.1049/nbt2/9824354

{"title":"Corrigendum to “Chitosan nanoparticle loaded by epidermal growth factor as a potential protein carrier for wound healing: In vitro and in vivo studies”","authors":"","doi":"10.1049/nbt2/9824354","DOIUrl":"10.1049/nbt2/9824354","url":null,"abstract":"[Montazeri, S., et al.: Chitosan nanoparticle loaded by epidermal growth factor as a potential protein carrier for wound healing: in vitro and in vivo studies. IET Nanobiotechnol. 17(3), 204–211 (2023). https://doi.org/10.1049/nbt2.12116]In Section 2.9 [In vivo wound healing study], the statement “In the present study, 20 mature Sprague-Dawley rats weighing 200–300 g were used” was incorrect. This should have read: “In the present study, 25 mature Sprague-Dawley rats weighing 200–300 g were used.”In Section 2.9 [In vivo wound healing study], the statement “The treatment started on day 0, wound dressing of each group was changed every day until the 14th day.” Was missing and is now included in the paragraph.In Section 2.9 [In vivo wound healing study], the ethical approval statement was missing. The statement has now been provided below:“All animal experiments in this study were performed with the approval of the Animal Ethics Committee of the Avicenna Research Institute under reference number IR.ACECR.Avicenna.REC.1396.19.”In Section 2.10 [Wound histological analysis], the statement “After 14 days, the animals were sacrificed by spinal cord injury under anaesthesia” was incorrect. This should have read: “After 14 days, the animals were euthanized using carbon dioxide (CO2).”In Table 1, the standard deviation (SD) values were missing. The correct version of the table [with the SD values] is provided below:The quality of the images in Figure 5a was inadvertently altered and decreased during the preparation and publication process. They have been replaced with images of higher quality.The conclusions reached within the study remain unaffected. The authors apologize for these errors.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"2025 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/nbt2/9824354","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143846138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2025-04-18

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RETRACTION: Trace elements-based Auroshell gold@hematite nanostructure: Green synthesis and their hyperthermia therapy 摘要：基于微量元素的aurroshell gold@hematite纳米结构：绿色合成及其热疗

IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2025-02-28 DOI: 10.1049/nbt2/9878750

IET Nanobiotechnology

{"title":"RETRACTION: Trace elements-based Auroshell gold@hematite nanostructure: Green synthesis and their hyperthermia therapy","authors":"IET Nanobiotechnology","doi":"10.1049/nbt2/9878750","DOIUrl":"10.1049/nbt2/9878750","url":null,"abstract":"RETRACTION: H. M. Alahdal, S. A. Abdullrezzaq, H. I. M. Amin, S. F. Alanazi, A. T. Jalil, M. Khatami, and M. M. Saleh, “Trace elements-based Auroshell gold@hematite nanostructure: Green synthesis and their hyperthermia therapy,” IET Nanobiotechnology 17, no. 1 (2023): 22–31, https://doi.org/10.1049/nbt2.12107.The above article, published online on 24 November 2022 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief; The Institution of Engineering and Technology; and John Wiley & Sons Ltd.The retraction has been agreed due to concerns raised by a third party. An investigation revealed several inconsistencies regarding the experiments described and the results presented. The experimental methods are not described in detail, and so the research described is not fully comprehensible for readers, not reproducible, and the editors consider the conclusions invalid. The authors were contacted for an explanation but have not addressed any of the concerns. They have been informed of the decision to retract and they disagree with it.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"2025 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/nbt2/9878750","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143513500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2025-02-28

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IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2025-02-19

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Silver Nanoparticles Seed Priming for Sustainable Enhancement of Durum Wheat Growth, Yield, and Nutrient Enrichment 纳米银种子注入对硬粒小麦生长、产量和养分富集的可持续促进

IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2025-02-19 DOI: 10.1049/nbt2/6152486

Yasser Al Salama, Ibrahim Alghoraibi, Raghad Zein, Mohammad Alsouse

{"title":"Silver Nanoparticles Seed Priming for Sustainable Enhancement of Durum Wheat Growth, Yield, and Nutrient Enrichment","authors":"Yasser Al Salama, Ibrahim Alghoraibi, Raghad Zein, Mohammad Alsouse","doi":"10.1049/nbt2/6152486","DOIUrl":"10.1049/nbt2/6152486","url":null,"abstract":"Achieving food security stands as a primary challenge confronting global societies today. This necessitates the development of effective strategies to increase crop productivity and enhance their specifications, aiming to meet the growing market demands sustainably and efficiently. This research was conducted over two agricultural seasons and emphasizes the ability of silver nanoparticles (AgNPs) to promote the growth and productivity of durum wheat (variety Sham 7) cultivated under the conservative conditions of Deir ez-Zor. The wheat seeds were soaked before planting with a colloidal suspension of AgNPs, prepared through an eco-friendly method utilizing an aqueous extract of Eucalyptus camaldulensis leaves. The best plant morphological indicators (plant height, chlorophyl content, number of branches, and number of spikes) were observed when colloidal AgNPs were used as a soaking solution compared with silver nitrate (AgNO3)and deionized (DI) water as a control. The highest productivity parameters (grain yield, straw yield, and 1000-grain weight) were obtained when seeds were soaked in 40 ppm of AgNPs. Furthermore, the results revealed an increase in the nutrient content of grain (nitrogen, phosphorus, and potassium). This study offers valuable insights into the prospective use of AgNPs for significant improvement in wheat cultivation, increasing productivity, and improving crop quality. As a contribution to facing future challenges in the field of agriculture and ensuring sustainable food security.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"2025 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/nbt2/6152486","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Mesenchymal Stem Cell Membrane-Derived Composite System for Enhancing the Tumor Treatment Efficacy of Metal–Organic Framework Nanoparticles 间充质干细胞膜衍生复合系统用于增强金属有机框架纳米粒子的肿瘤治疗功效

IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2024-12-04 DOI: 10.1049/nbt2/1069307

Ying Tong, Meng Gao, Yingli Luo

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PLGA-PEG-c(RGDfK)-Kushenol E Micelles With a Therapeutic Potential for Targeting Ovarian Cancer PLGA-PEG-c(RGDfK)-Kushenol E胶束具有靶向卵巢癌的治疗潜力

IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2024-11-29 DOI: 10.1049/nbt2/7136323

Xue Chen, Haopeng Wan, Lijuan Lu, Ran Li, Bo Sun, Juan Ren

{"title":"PLGA-PEG-c(RGDfK)-Kushenol E Micelles With a Therapeutic Potential for Targeting Ovarian Cancer","authors":"Xue Chen, Haopeng Wan, Lijuan Lu, Ran Li, Bo Sun, Juan Ren","doi":"10.1049/nbt2/7136323","DOIUrl":"10.1049/nbt2/7136323","url":null,"abstract":"Background: As a naturally derived inhibitor of autophagy, Kushenol E (KE) is a biprenylated flavonoid and is isolated from Sophora flavescens, which has been used for the treatment of cancer, hepatitis, and skin diseases. However, KE, as a poorly soluble drug, exhibited strong autophagy regulating activity in in vitro cancer cell lines, but no related studies have reported its antiovarian cancer property. Therefore, it is very beneficial to enhance the antineoplastic properties of KE by establishing an ovarian tumor-targeting nanoparticle system modified with tumor-homing c(RGDfK) peptides.Materials and Methods: In the current study, poly(lactic-co-glycolic acid)-poly(ethylene glycol)-modified with cyclic RGDfK peptide (PLGA-PEG-c(RGDfK))-KE micelles (PPCKM) were prepared to overcome the poor water solubility of KE to meet the requirement of tumor-active targeting. The effect of PPCKM on ovarian cancer was evaluated on SKOV-3 cells and xenograft models in BALB/c nude mice.Results: The PPCKM showed a higher drug cumulative release ratio (82.16 ± 7.69% vs. 34.96 ± 3.05%, at 1.5 h) with good morphology, particle size (93.41 ± 2.84 nm), and entrapment efficiency (89.7% ± 1.3%). The cell viability, migration, and apoptosis analysis of SKOV-3 cells demonstrated that PPCKM retained potent antitumor effects and promoted apoptosis at early and advanced stages with concentration-dependent. Based on the establishment of xenograft models in BALB/c nude mice, we discovered that PPCKM reduced tumor volume and weight, inhibited proliferating cell nuclear antigen (PCNA) and Ki67 expression, as well as promoted apoptosis by targeting the tumor site.Conclusion: The findings in this study suggest that PPCKM may serve as an effective therapeutic option for ovarian cancer.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"2024 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/nbt2/7136323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Nanocodelivery of 5-Fluorouracil and Curcumin by RGD-Decorated Nanoliposomes Achieves Synergistic Chemotherapy for Breast Cancer 通过RGD蜕变纳米脂质体纳米递送5-氟尿嘧啶和姜黄素实现乳腺癌的协同化疗

IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2024-11-25 DOI: 10.1049/nbt2/4959295

Reza Mahmoudi, Somayeh Mohammadi, Rouzbeh Mahmoudi, Mohamad Hassan Fouani, Maryam Tajali Ardakani, Amin Hadi, Mohsen Nikseresht, Mehrzad Jafari Barmak, Farzad Karimpour, Hassan Bardania

{"title":"Nanocodelivery of 5-Fluorouracil and Curcumin by RGD-Decorated Nanoliposomes Achieves Synergistic Chemotherapy for Breast Cancer","authors":"Reza Mahmoudi, Somayeh Mohammadi, Rouzbeh Mahmoudi, Mohamad Hassan Fouani, Maryam Tajali Ardakani, Amin Hadi, Mohsen Nikseresht, Mehrzad Jafari Barmak, Farzad Karimpour, Hassan Bardania","doi":"10.1049/nbt2/4959295","DOIUrl":"10.1049/nbt2/4959295","url":null,"abstract":"In the present study, arginine–glycine–aspartic acid peptide (RGD) surface functionalized liposomes (Lips) were formulated for the concomitant targeted delivery of two antineoplastic drugs, namely curcumin (Cur) and 5-fluorouracil (5FU) to breast cancer cells. The Lips’ measured size values where 50–100 nm by transmission electron microscopy (TEM) and 169 ± 10.2 nm by dynamic light scattering (DLS), which fall within the desired range required for drug delivery purposes. In this study, we assessed the antineoplastic effects of various liposomal formulations for the codelivery of Cur and 5FU to MCF-7 breast cancer cells. We evaluated two liposomal formulations (Lip–Cur–5FU) and (Lip–Cur–5FU–RGD). The treatment of MCF-7 cells with 32 µg/mL of Cur exhibited a significant (p < 0.0001) drop in cell viability among the three formulations, namely Cur and 5Fu in the free form (Lip–Cur–5FU) and liposomal form (Lip–Cur–5FU–RGD); the least viability rate (9.91% ± 1.65%) corresponded to the RGD functionalized concomitantly Cur and 5Fu loaded Lips (Lip–Cur–5FU–RGD) formulation. On the other hand, liposomal Cur increased the rate of early apoptotic cell by 4.88% without altering the rate of late apoptotic cells. Furthermore, the concomitant treatment of MCF-7 cells with Cur and 5FU enhanced the overall apoptosis rate, where Cur–5FU in the RGD functionalized-liposomal form induced the highest (16.8%) apoptosis rate, while other Cur–5FU formulations, free and nonfunctionalized liposomal form, induced lower apoptosis rates (10.4% and 10.9%, respectively). Collectively our results demonstrated that the implementation of RGD-functionalized Lips for the concomitant delivery of Cur and 5FU enhanced their therapeutic efficacy against this breast cancer model.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"2024 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/nbt2/4959295","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142708391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Linum usitatissimum Delivery over Chitosan Nanobiopolymer: Enhanced Effects on Polycystic Ovary Syndrome Condition 壳聚糖纳米生物聚合物输送亚麻：增强对多囊卵巢综合征的疗效

IF 4.9 4区工程技术

IET nanobiotechnology Pub Date : 2024-07-17 DOI: 10.1049/2024/6693566

Abolfazl Bayrami, Maryam Sojoudi, Shima Rahim Pouran, Aziz Habibi-Yangjeh, Sanaz Sojoudi

{"title":"Linum usitatissimum Delivery over Chitosan Nanobiopolymer: Enhanced Effects on Polycystic Ovary Syndrome Condition","authors":"Abolfazl Bayrami, Maryam Sojoudi, Shima Rahim Pouran, Aziz Habibi-Yangjeh, Sanaz Sojoudi","doi":"10.1049/2024/6693566","DOIUrl":"10.1049/2024/6693566","url":null,"abstract":"Herein, chitosan nanoparticle (CHIT) was used as a safe and biocompatible matrix to carry flaxseed (Linum usitatissimum L.) extract (FSE). The number of main features and bio-interface properties of CHIT-FSE were determined by SEM, DLS, FTIR, XRD, TGA, and zeta potential analyses and compared to those of chitosan lacking FSE. A GC–MS analysis was also conducted to reveal the bioactive compounds of FSE. The active anchoring of the FSE phytomolecules over chitosan nanoparticles with enhanced thermal and structural stability was correspondingly verified. Subsequently, the influence of CHIT-FSE, CHIT-TPP, and FSE supplementation was assessed on hormonal and biochemical markers of polycystic ovary syndrome (PCOS) in female rats and compared with untreated and healthy control groups. After 16 days of treatment, CHIT-FSE represented the best performance for controlling the serum levels of the studied biochemical (lipid profile and blood glucose level) and hormonal (insulin, testosterone, luteinizing, and follicle-stimulating hormone) parameters. Considering the negligible therapeutic activity of CHIT-TPP, the enhanced activity of CHIT-FSE compared to only FSE was expounded based on the potent action of chitosan nanoparticles in enhanced stabilization, bioavailability, transport, and permeability of the therapeutically important phytomolecules. As per the results of this investigation, supporting medically important biomolecules over chitosan can enhance their therapeutic effectiveness in controlling PCOS.","PeriodicalId":13393,"journal":{"name":"IET nanobiotechnology","volume":"2024 1","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/2024/6693566","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141639570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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