Mrinal Kanti Das , Amit Malviya , Geevar Zachariah , Sivasubramanian Ramakrishnan , Abdullakutty Jabir , Venugopal Krishnan Nair , Neil Bardoloi , Dhurjati Prasad Sinha , Partho Sartha Banrjee , S. Shanmugasundaram , Gurpreet Singh Wander , Dhiman Kahali , Debabrata Roy , Rakesh Yadav
{"title":"Gender bias in acute myocardial infarction care in India: Nationwide retrospective study of 41832 patients","authors":"Mrinal Kanti Das , Amit Malviya , Geevar Zachariah , Sivasubramanian Ramakrishnan , Abdullakutty Jabir , Venugopal Krishnan Nair , Neil Bardoloi , Dhurjati Prasad Sinha , Partho Sartha Banrjee , S. Shanmugasundaram , Gurpreet Singh Wander , Dhiman Kahali , Debabrata Roy , Rakesh Yadav","doi":"10.1016/j.ihj.2025.01.001","DOIUrl":"10.1016/j.ihj.2025.01.001","url":null,"abstract":"<div><h3>Background</h3><div>Various studies have documented gender differences in the management and outcomes of acute myocardial infarction (AMI) in developed countries. Gender differences in the management of AMI in India is not known.</div></div><div><h3>Objectives</h3><div>To document the gender differences in the management and outcomes of AMI in India.</div></div><div><h3>Methods</h3><div>The current study was a nationwide retrospective, multicenter, cross-sectional study including all consecutive AMI patients admitted from 15th March to 15th June in the year 2020 using a historical control of all cases of AMI admitted during the corresponding period in the year 2019.</div></div><div><h3>Results</h3><div>There were only 9018 females (21.6 %) among the 41832 patients with AMI in the study. Females were older and were more likely to present with non ST-elevation MI than men (41.6 % vs. 33.2 %). Significantly fewer number of females underwent primary percutaneous coronary intervention (29.5 % vs 31.2 % <em>p</em> value < 0.001), thrombolysis (32.9 % vs 34.7 %, <em>p</em> value < 0.001), pharmaco-invasive therapy (18.6 % vs 20.7 % <em>p</em> value 0.001). Females had higher in-hospital mortality (7.07%vs 4.07 %, p < 0.001), length of hospital stay (3.9 ± 2.98 days vs 3.8 ± 2.88 days, p < 0.001) and complications of AMI [cardiogenic shock (8.6 % vs 6.3 %), mechanical complications (4.6 % vs 3.8 %), heart failure (13.9%vs 11.7 %) and malignant arrhythmias (3.4%vs2.8 %)] than males.</div></div><div><h3>Conclusions</h3><div>Differences between gender in the presentation, management, and outcomes of acute MI are prevalent in India. Women with acute MI presented at older age, had higher in-hospital mortality and complications, and received revascularization therapy less often compared to men.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 1","pages":"Pages 22-27"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142948095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hager Allam, Shaimaa Mostafa, El-Sayed Abd Khalek, Sara Abdalla
{"title":"Predictive role of CHA₂DS₂-VASc score in acute coronary syndrome patients and value of adding global longitudinal strain to CHA₂DS₂-VASc score","authors":"Hager Allam, Shaimaa Mostafa, El-Sayed Abd Khalek, Sara Abdalla","doi":"10.1016/j.ihj.2024.12.001","DOIUrl":"10.1016/j.ihj.2024.12.001","url":null,"abstract":"<div><h3>Background</h3><div>Future clinical management would be improved by accurate and early identification of ACS patients at high CV risk. In non-valvular atrial fibrillation patients, the prognostic risk of thromboembolism has been evaluated using CHA₂DS₂-VASc scores. It has recently been shown to assess the severity of CAD and foresee patient outcomes. Also, LV global longitudinal strain is an independent predictor of outcome. <strong>Our study aimed</strong> to determine the added value of LV longitudinal strain (GLS) to CHA₂DS₂-VASc in predicting the outcome and severity of CAD in patients with acute coronary syndrome (ACS).</div></div><div><h3>Methods</h3><div>A total of 577 patients with primary diagnosis of ACS were included between January and July 2021. All patients had evaluations based on history, clinical examination, 12-lead ECG, TTE, and coronary angiography. Six months follow-up had been provided to all patients.</div></div><div><h3>Results</h3><div>Syntax score was significantly higher among patients with high-risk CHA₂DS₂-VASc score (30.5 ± 6.1 <strong>vs.</strong> 17.34 ± 8.7 <strong>vs.</strong> 11.11 ± 8.2), <em>p</em>-value <0. 001. GLS was significantly lower among high SYNTAX score (−10.97 ± 2.68 vs. −12.61 ± 3.46 vs. −17.81 ± 2.89), <em>p</em>-value = 0.0001. There was a significant negative correlation between the CHA₂DS₂-VASc score and GLS. Moreover, adding GLS to CHA₂DS₂-VASc score significantly improved overall accuracy for the prediction of outcome and severity of CAD in ACS patients.</div></div><div><h3>Conclusions</h3><div>CHA₂DS₂-VASc score is an easy and simple parameter that can be used in predicting the severity of CAD & adverse clinical outcome in ACS patients and adding GLS to the CHA₂DS₂-VASc score significantly improved overall accuracy.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 1","pages":"Pages 1-6"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IVUS derived plaque characteristics and outcomes in patients with acute coronary syndrome undergoing percutaneous intervention","authors":"Sajan Narayanan , Vijayakumar Subban , Parayaru Kottayil Asokan , Ramesh Natarajan , K. Latchumanadhas , V.V. Krishnakumar , Gopi Aniyathodiyil , Ravi Cheriyan Mathew , M. Shifas Babu , ArjunS. Shenoi , UdayKhanolkar , C.G. Bahuleyan","doi":"10.1016/j.ihj.2025.02.001","DOIUrl":"10.1016/j.ihj.2025.02.001","url":null,"abstract":"<div><h3>Background</h3><div>No/slow flow after percutaneous intervention(PCI) for acute coronary syndromes (ACS) is common. Whether a comprehensive intravascular ultrasound (IVUS) analysis of atherosclerotic plaque can define characteristics which predict suboptimal flow following PCI is largely unknown.</div></div><div><h3>Objectives</h3><div>To identify IVUS correlates of suboptimal flow in patients with ACS undergoing PCI.</div></div><div><h3>Materials & methods</h3><div>We performed a prospective multicentre, investigator initiated study. Patients with ACS, who underwent IVUS guided PCI were enrolled. Clinical, angiographic and imaging characteristics of patients who developed suboptimal flow after PCI were analysed and compared with patients with normal flow.</div></div><div><h3>Results</h3><div>Between October 2021 and August 2022, we enrolled 187 patients (195 lesions) with ACS who underwent IVUS guided PCI. Mean age of patients was 58 ± 10.4 years; Incidence of slow/no reflow in our study was 14/195 (7.2 %). Presentation as ST elevation myocardial infarction, presence of angiographically complex lesion type (type B2/C) and pre procedural TIMI flow 0 were significantly more in patients who developed suboptimal flow after PCI. Pre PCI plaque attenuation length (9.51 mm Vs 4.35 mm p = 0.037), lesion site positive remodelling (Odds ratio 6.4 : 95 % CI; 1.1–38.4 p = 0.042) were predictors of slow flow.Post PCI length of plaque prolapse (9.73 mm Vs 6.58 mm p = 0.029) correlated with slow flow.</div></div><div><h3>Conclusions</h3><div>Plaque characteristics on IVUS in patients with ACS helps to identify patients who may develop suboptimal flow following PCI.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 1","pages":"Pages 36-41"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Titrating statin therapy according to lipid response - Can dose of statins be reduced during long term follow up of revascularized patients?","authors":"Satish Poshattiwar, Niteen Deshpande, Mohan Deshpande, Parag Admane, Namrata Khandelwal, Manjush Mardikar","doi":"10.1016/j.ihj.2024.11.040","DOIUrl":"10.1016/j.ihj.2024.11.040","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"76 ","pages":"Pages S19-S20"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gender Based Differences in Circulating Micro RNA Levels in Patient Presenting with Acute Myocardial Infarction and Their Correlation with Treatment Outcome and 30 Day Mortality","authors":"Shanky Jain, Girish M. P, Mohit Gupta, Subrat Muduli, Binita Goswami","doi":"10.1016/j.ihj.2024.11.038","DOIUrl":"10.1016/j.ihj.2024.11.038","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"76 ","pages":"Pages S18-S19"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echocardiographic Assessment of Different Mechanisms of Ischemic Mitral Regurgitation in Patients with Inferior and Anterior Myocardial Infarction","authors":"Arvind Kumar, Gopi A","doi":"10.1016/j.ihj.2024.11.090","DOIUrl":"10.1016/j.ihj.2024.11.090","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"76 ","pages":"Pages S43-S44"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left Ventricular longitudinal and circumferential function assessment by two-dimensional speckle tracking echocardiography in Type 2 Diabetes Mellitus: Effect of glycemic control and microalbuminuria on left ventricular strain in asymptomatic Type 2 DM patients","authors":"Rahul Gudaghe, Atul Kaushik","doi":"10.1016/j.ihj.2024.11.068","DOIUrl":"10.1016/j.ihj.2024.11.068","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"76 ","pages":"Pages S31-S32"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prayaag Kini , Reeta Varyani , B. Barooah , Yalavarthy
{"title":"A Novel Multi-Modality based Risk-Prediction model for Ventricular Arrhythmias in HCM/HOCM using the Electro-mechanical window - Opening a “Window of opportunity”","authors":"Prayaag Kini , Reeta Varyani , B. Barooah , Yalavarthy","doi":"10.1016/j.ihj.2024.11.017","DOIUrl":"10.1016/j.ihj.2024.11.017","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"76 ","pages":"Pages S7-S8"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of Right Ventricular Function following Permanent Pacemaker Implantation by Echocardiography (Including 3D Echocardiography)","authors":"Dinesh Kumar, Bornali Dutta, Farhin Iqbal","doi":"10.1016/j.ihj.2024.11.004","DOIUrl":"10.1016/j.ihj.2024.11.004","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"76 ","pages":"Page S1"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}