Indo Global Journal of Pharmaceutical Sciences最新文献_第3页

Human Monkeypox-An Update 人类猴痘——最新进展

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12032

Johra Khan

引用次数: 1

Preparation and Evaluation of Directly Compressible Tablets of Ibuprofen Crystals 布洛芬晶体直接可压片的制备及评价

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12019

Pooja D. Vaghela, N. Patel, H. M. Tank

引用次数: 0

Vaccination Strategies for Monkey Pox: An Update 猴痘疫苗接种策略:最新进展

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12031

Hitesh Chopra, Amanpreet Kaur

引用次数: 1

Formulation of Silver Nanoparticle of Cassia angustifoliaby Using Green Synthesis Method and Screening for In-Vitro Anti-Inflammatory Activity 绿色合成法制备消炎决明子纳米银颗粒及体外抗炎活性筛选

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12022

Priyanka Annaso. Patil, Shubdha Dalvi, Vishwajit D. Dhaygude, Sanmati D. Shete

{"title":"Formulation of Silver Nanoparticle of Cassia angustifoliaby Using Green Synthesis Method and Screening for In-Vitro Anti-Inflammatory Activity","authors":"Priyanka Annaso. Patil, Shubdha Dalvi, Vishwajit D. Dhaygude, Sanmati D. Shete","doi":"10.35652/igjps.2022.12022","DOIUrl":"https://doi.org/10.35652/igjps.2022.12022","url":null,"abstract":"The main objectives in developing nanoparticles as a delivery system are to manage particle size, surface characteristics, and the release of pharmacologically active substancesto achieve the drug's site-specific action at the appropriate rate and dose. They can help boost medication stability and have helpful controlled release features, for example.Nowadays researchers are movingtowards the green chemistry approach which is an alternative routethat is eco-friendly, cheap and fast; in that plant extracts and microorganisms are used in the reduction of the metal salt which is fast gaining demand in the field of nanobiotechnology. In this study, silver nitrate was reduced to its “nanosilver form”through a one-step synthesis protocol using an extract of Cassia Angustifolia.Three different batches namely batch A, B, C of varying temperature and another three batches namely D,E,F of varying pH were synthesized. The prepared nanoparticles were optimized and characterized by practical yield determination, drug entrapment efficiency, particle size determination and measurement of zeta potential. The synthesized nanoparticles were screened for in vitro anti-inflammatory activity.Result found that the percentage practical yield of synthesized nanoparticles waswithin the range of 6.41-52.61%. The drug entrapment efficiency was found to be 99.875%. AgNPs inhibited protein denaturation and showed 75.52% inhibition at 500μg ml-1 whereas standard drug Aspirin exhibited 65.03% protein denaturation.©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85245296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Effect of Temperature and Preservation Period on the Viability of Lyophilized Bacillus subtilis 温度和保存期对枯草芽孢杆菌冻干菌活力的影响

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12017

Kim Vanessa Phoane, E. Tjoa, Shikha Joon, Listya Utami Karmawan, L. Moehario

{"title":"Effect of Temperature and Preservation Period on the Viability of Lyophilized Bacillus subtilis","authors":"Kim Vanessa Phoane, E. Tjoa, Shikha Joon, Listya Utami Karmawan, L. Moehario","doi":"10.35652/igjps.2022.12017","DOIUrl":"https://doi.org/10.35652/igjps.2022.12017","url":null,"abstract":"Objective: We sought to study the effect of temperature and preservation period on the viability of lyophilized Bacillus subtilis. Methods: Forty-five test tubes that contained suspension of B. subtilisATCC 6633 were incubated for 4 hours at37°Candwashedtwicebeforefreeze-drying.Next, thelyophilizedbacteriawereexposed to different temperatures (-20°C, 2-8°C, and 25°C) and storage periods (30 days, 120 days, and 240 days). Further, the lyophilizedbacteriawere evaluated for their viability using the Milesand Misramethod.Finally, the colony count of B.subtilisineach group was compared andanalyzed using the two-way ANOVA and the Tukey-test (post-hoc test).Results: The lyophilized B. subtilisshowed the viability of 93.3% (42/45) of test tubes. All of the lyophilized B.subtilisstored at -20°C for 30, 120, and 240 days remained viable while the bacteria stored at 2-8°C and 25°Cshowed the viability of 93.3% (14/15) and 86.6%, respectively. The lyophilized B. subtilisstored at three grouptemperatures and kept for 120 and 240 days showed a significant decline in their number over thecontrolgroup(p <0.05). Conclusion: In conclusion, the temperature and preservation period significantly affect the viability of the lyophilized B. subtilis.©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"2013 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86221129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

In vitro Evaluation of Physicochemical Properties of Polyherbal Anti-Wrinkle Cream 复方抗皱霜的体外理化性能评价

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12026

Usha Kiranmai G, Shayeda

{"title":"In vitro Evaluation of Physicochemical Properties of Polyherbal Anti-Wrinkle Cream","authors":"Usha Kiranmai G, Shayeda","doi":"10.35652/igjps.2022.12026","DOIUrl":"https://doi.org/10.35652/igjps.2022.12026","url":null,"abstract":"Purpose: Skin ageing can be described as irregular pigmentation, increased wrinkling, loss of elasticity, dryness and roughness. Wrinkling of the skin is the most obvious sign of deterioration of the human body with age. Herbal cosmetics enhance the human appearance by playing a major role in impeding and reversing the ageing of the skin. Method: In this study, anti wrinkle creams were formulated with herbal oils of different concentrations namely AW1, AW2, AW3 and AW4. All cream formulations were evaluated for different parameters like pH, viscosity, spreadability, stability studies etc. The creams were found to be stable during stability studies done according to ICH guidelines. All in vitro tests results were analyzed statistically using SPSS software 17.0 version and compared with standard marketed formulations. Results: The formulated creams were consistent in quality and safe to be used on the skin. The Anti Wrinkle creams showed no evidence of phase separation and ease of removal. The creams were not shownany redness, edema, inflammation and irritation to the skin during skin irritation studies. The formulated creams were found statistical significant difference with that of standard at p<0.05. Conclusion: Formulations AW2 and AW4 showed good pH, viscosity, homogeneity, good spreadability, good extrudability with good appearance during the three months of stability studies. ©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85887917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Indigenous Study on Malassezial Susceptibility Testing by Selected Plant Extracts 植物提取物对马拉塞菌药敏试验的研究

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12033

{"title":"An Indigenous Study on Malassezial Susceptibility Testing by Selected Plant Extracts","authors":"","doi":"10.35652/igjps.2022.12033","DOIUrl":"https://doi.org/10.35652/igjps.2022.12033","url":null,"abstract":"he present study was carried out to evaluate the antifungal activity of tenselected plant extracts of Nelumbo nucifera,Senna auriculata, Salvia officinalis, Tagetes erecta,Psidium guajava,Argemone mexicana,Hibiscussabdariffa, Hemidesmus indicus, Moringa oleifera,andGlycyrrhizaglabrawith ketoconazole as the positive reference standard. Their antimalassezial efficacy was tested using different concentrations of extracts in various solvents. The preliminary screening of plant extracts was determined by Kirby Bauer disc diffusion method and among the tenplantextracts, aqueous extract of S.officinalisand ethanol extract of H.sabdariffaextract exhibited potent antifungal activity against Malasseziafurfur. The purification and partial characterization of H. sabdariffa and S.officinalis were carriedout by Thin layer chromatography (TLC) technique.The Minimum Inhibitory Concentration (MIC) of H.sabdariffa andS.officinalisagainst M. furfur by Kirby Bauer method was0.312mg/mLand 0.625mg/mLrespectively against 50 μg/mLof Ketoconazole which was used as the standard. The phytochemical analysis of S.officinalis and H.sabdariffa revealed the presence of terpenoids, steroids, tannins, and polyphenols of which the concentration of polyphenols and flavonoids were significantly higher in S.officinalisand H.sabdariffa respectively. Thus, the present study concludes that S.officinalisand H.sabdariffa havea potent activity against M. furfur, thereby reducing the prevalence of dandruff, provided the future perspectives of the study that includecharacterization and cytotoxicity of the compound.©2022Caproslaxy Media. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85087778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study to Assess the Efficacy of Wheatgrass Juice Therapy Intervention on Haemoglobin Level in Adolescent Anaemic Females 麦草汁治疗干预青少年贫血女性血红蛋白水平的研究

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12003

Deepak, Lakshmeesha D R

{"title":"Study to Assess the Efficacy of Wheatgrass Juice Therapy Intervention on Haemoglobin Level in Adolescent Anaemic Females","authors":"Deepak, Lakshmeesha D R","doi":"10.35652/igjps.2022.12003","DOIUrl":"https://doi.org/10.35652/igjps.2022.12003","url":null,"abstract":"Background and Objectives:Wheatgrass juice is rich in various minerals like iron, magnesium, calcium, phosphorus, antioxidants like beta carotene,and insoluble dietary fibers. It has a significant amount of medicinal value with a rich source of Chlorophyll. The chemical structure of Chlorophyll is almost identical to Haemoglobin. The only difference is that magnesium is a central element in chlorophyll and iron in Haemoglobin.The vital component of wheatgrasshelps in building Haemoglobin in our body. Thus,it is used therapeutically forvarious clinical conditions involving Haemoglobin deficiency and other chronic disorders ultimately it is considered as green blood.Adolescents are susceptible to both macro and micronutrient deficiencies. Adolescent girls are mainly vulnerable groupsdue to blood loss during menstruation and poor dietary habits.The present study aims to evaluate the effect of wheatgrass fresh juice on the Haemoglobin level of adolescent anemic females. Materials and Methodology:60 subjects were selected with Haemoglobinless than 10mg/dl anddivided into two groups. Group 1-Study group wasgiven 30ml of freshly prepared wheatgrass juice on empty stomach daily for 60 days. Where Group 2-Control groupwere observed with regular activities.Results: After 60 days the symptomatic improvement and increase in Haemoglobin level in the study group was noticed as compared to the control group. Conclusion:Wheatgrass juice consumption will improve the Haemoglobin levels among anemic adolescent femalesIndex.©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85971961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Design and Characterization of Sustained Release Tablet Formulation Containing Metformin Hydrochloride and Simvastatin 盐酸二甲双胍与辛伐他汀缓释片配方设计与表征

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12013

S. Dhobale, Sayali Nilakh, S. Jadhav

{"title":"Design and Characterization of Sustained Release Tablet Formulation Containing Metformin Hydrochloride and Simvastatin","authors":"S. Dhobale, Sayali Nilakh, S. Jadhav","doi":"10.35652/igjps.2022.12013","DOIUrl":"https://doi.org/10.35652/igjps.2022.12013","url":null,"abstract":"The aim of the present work was to develop pharmaceutical combinational dosage form for simultaneous treatment of patients with type 2 diabetes with at high-risk of coronary disease associated co-morbidities. Metformin, an antidiabetic drug is used to treat the diabetic patient and combined with Simvastatin which is HMG-CoA reductase inihibitor drug to treat the high-risk coronary disease simultaneously. In this formulation, three batches were prepared by the direct compression method. Preformulation parameters such as identification, solubility, melting point, compatibility studies, Pre-compression parameters such as bulk density, tapped density, angle of repose, Hausner ratio, compressibility index, and Post-compression parameters like weight uniformity, hardness, drug content, thickness, in-vitrodrug release. In-vitrodrug release of all formulations, B1, B2, and B3 was carried out in 0.1N HCl for 2hrs and 10 hrs in phosphate buffer (pH 6.8) dissolution media. Among all the formulations, B3 was an optimized batch. B3 formulations showed drug release of 85% for Metformin Hydrochloride and 93% for Simvastatin over a period of 12hrs.©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90701153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comprehensive Review on Rising Concern of Transmission Potential of Monkeypox Virus on Healthcare System 猴痘病毒在卫生保健系统传播潜力日益受到关注的综述

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12035

R. Goyal, Mohini Devi, Rupesh K. Gautam, Sumeet Gupta

{"title":"A Comprehensive Review on Rising Concern of Transmission Potential of Monkeypox Virus on Healthcare System","authors":"R. Goyal, Mohini Devi, Rupesh K. Gautam, Sumeet Gupta","doi":"10.35652/igjps.2022.12035","DOIUrl":"https://doi.org/10.35652/igjps.2022.12035","url":null,"abstract":"Over the past few years, thecountriesof the worldhave been afflictedwith numerousinfectious ailments. As the terrorof the COVID-19diseasewidespread decreases, nations throughoutthe worldare facing the terrorof the epidemic surrounding the pervasivenessof the geographical spread of human monkeypox cases worldwide. Thus,several approachesto decimate therisingspread of the monkeypox virus (MPXV) are warranted.MPXVcases received global attention during the 1970s, emanatingfromAfrica has fully-fledgedto be a universalconcern with MPXV cases reportedin Israel, Singapore,the United Kingdom,and the United States.Monkeypoxappears asa zoonotic viral diseasethat isinstigatedviathe monkeypox virus recognizedas the most criticalorthopoxviralinfection in humans. Transmissionof the monkeypoxvirusto human beingsis allegedto occur viadirect exposure toinfected animals or it can probablybe transmittedviaconsuminginfected meat,orblood. The transmission from humanto human takesplacethroughthe respiratory route(droplets),virus-contaminated material,and directcontact(skin-to-skin or sexual). This diseasemay be caused several difficultiesincluding,headache,fever, malaise, back pain, rash, and lymphadenopathies. Presently,there is no proven therapyfor its treatment,thusmonkeypox virus is considered a major threat to global health security. In this review, we discussed thetransmission potential of the monkeypox virus on the healthcare system, itsepidemiology, mode of transmission,and different diagnostic, preventive,and treatment approaches.©2022Caproslaxy Media. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87322900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1