Indo Global Journal of Pharmaceutical Sciences最新文献_第2页

Booster Dose for Tackling Emerging Variant of SARS-CoV-2 应对新出现的SARS-CoV-2变体的加强剂

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12028

Ajay Kumar, Anupam Kumar, R. Banerjee, Nayan Das

{"title":"Booster Dose for Tackling Emerging Variant of SARS-CoV-2","authors":"Ajay Kumar, Anupam Kumar, R. Banerjee, Nayan Das","doi":"10.35652/igjps.2022.12028","DOIUrl":"https://doi.org/10.35652/igjps.2022.12028","url":null,"abstract":"A novel species of coronavirus has engulfed the entire world. Its severity and rate at which it transmits have left no country untouched. Massive replication has brought mutation in the genomic sequence of the virus. Due to this, many newer variants of SARS-COV-2 have come into play. Many therapies are available for covid 19, such as Remdesivir, Baricitinib, Molnupiravir, etc., but none are effective at preventing SARS-CoV-2 infection. Even most of the efficacious vaccines against the earlier variants are now inefficacious against, the newer variants. So, the people already vaccinated with the primary course of vaccination are at risk of reinfection and symptomatic COVID 19 illness.Furthermore, the initial immune response produced by these vaccines may have diminished with time, paving the pathway for discussion on the absolute need for time off and booster doses for vaccinated people. Some developed countries like the U.K and Israel favor the booster dose strategy, while some defy it, claiming it is necessary to vaccinate unvaccinated people first rather than giving vaccines multiple times. In this article, we have explained the necessity of booster doses in tackling newer variants. However, for the time being, devising a variant-specific vaccine seems promising to hiatus this transmission.©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91230790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Translation of Gold Nanoparticles into Effective Neuromedicines: Bottlenecks & Future Prospects 金纳米颗粒转化为有效神经药物的临床研究:瓶颈与未来展望

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12005

N T Pramathesh Mishra, Shalini Yadav, Mayank Khantwal, Wasim Khan, Salman Khan

引用次数: 2

Emulgel –Emerging as a Smarter Value-Added Product Line Extension for Topical Preparation 乳液-作为外用制剂的智能增值产品线的延伸

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12008

Neelam Patel, S. Chaudhary, Ankit Chaudhary

引用次数: 2

Biased Studies and Sampling from LGBTQ Communities Created a Next-Level Social Stigma in Monkeypox: A Public Health Emergency of International Concern (PHEIC) 来自LGBTQ社区的有偏见的研究和抽样造成了猴痘的下一级社会耻辱:国际关注的突发公共卫生事件(PHEIC)

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12025

Rajeev K. Singla, Shailja Singla, Bairong Shen

{"title":"Biased Studies and Sampling from LGBTQ Communities Created a Next-Level Social Stigma in Monkeypox: A Public Health Emergency of International Concern (PHEIC)","authors":"Rajeev K. Singla, Shailja Singla, Bairong Shen","doi":"10.35652/igjps.2022.12025","DOIUrl":"https://doi.org/10.35652/igjps.2022.12025","url":null,"abstract":"Since 2020, we are witnessing a COVID-19 pandemic that has ruled out all other pandemics ever happened in our history. Countries are still not be able to manage the COVID-19 threat properly, and while we are still dealing with it, here comes another deadlyinfectious disease, monkeypox. Rapid circulation of monkeypox infections worldwide has forced the WHO to declared it as PHEIC. As per the current reports available on WHO, though the monkeypox is alarmingly spreading, but this threat seems to be quite manageable if dealt properly with smallpox vaccine and other antibiotic regimens in proper place. Key challenge now is actually how to control misinformation and misleading news that flooded the social media and news outlets. We have gathered studies available on the PubMed search engine since the starting of 2022, and also collected relevant information from WHO and other reliable news sources. As on 27.07.2022, WHO reported 19,178 laboratory confirmed cases, and out of these, on the white paper, only for 31.8% cases, there was recorded information about the sexual orientation. But if we look at the scientific publications and social media, it is only men having sex with men (MSM) who are the main victims and having monkeypox infections. Same message is being circulated to the common public through such channels. It is thus becoming responsibility of WHO, government and public health agencies to properly guide the public and aware them about the misleading information. Further, the presence of monkeypox DNA in the urine and feces have again showcased the role of wastewater management and proper surveillance.©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82932366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

In vitroAxillary Mass Multiplication of Trichodesma indicum 籼稻赤霉病的体外腋窝大量增殖

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12015

Shameema Yousuf, Santosh Kumar Singh

引用次数: 0

Nutraceuticals in the Work of Scribonius Largus, a Pioneer of Clinical Pharmacy in Ancient Rome 古罗马临床药学先驱斯克里博尼乌斯·拉格斯著作中的营养药品

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12021

C. Tsagkaris, L. Matiashova, Andreas S. Papazoglou, Dimitrios V. Moysidis, A. Loudovikou, A. Alexiou, S. Papadakos

引用次数: 0

A Brief Overview on the Health Benefits of Nyctanthes arbor-tristisLinn.-A Wonder of Mother Nature 菊科植物三叶草的保健作用综述。-大自然的奇迹

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12024

Ria Chakraborty, Santa Datta(De)

{"title":"A Brief Overview on the Health Benefits of Nyctanthes arbor-tristisLinn.-A Wonder of Mother Nature","authors":"Ria Chakraborty, Santa Datta(De)","doi":"10.35652/igjps.2022.12024","DOIUrl":"https://doi.org/10.35652/igjps.2022.12024","url":null,"abstract":"Ayurveda is one of the oldest systems of drugs. It principally uses plants and their extracts for treatment and management of assorted diseases. Nyctanthes arbor-tristisLinn.(NAT) is documented Indian ancient plant that has high medicative worth in Ayurveda. It’s popularly called Parijat or Harsingar principally found in southern elements of Asian nation & Nepal etc. Phytochemicals like flavanol organic compound, oleanic acid, essential oils, phenol, carotene, friedeline, lupeol, glucose, benzoic acid have been reported for vital hepatoprotective, anti-allergy, antianxiety, anti-filarial, antianemia, antidiabetic, antimalarial, antibacterial, anti-inflammatory, anticancer activities. Each a district of the plant has some specifichealthful price and is so commercially exploitable. Thus,it’s thought of as a valuable supply of some distinctive medicative, merchandise formation against numerous diseases. The descriptions of scientific classification, family and genus characters, vernacular names, habitat, morphology, ancient medicine, therapeutic use etc. are richly mentioned throughout this criticism. ©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78838192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Microsponge as Novel Drug Delivery System: A Review 微海绵作为新型给药系统的研究进展

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12002

Pratima Jayasawal, N. G. R. Rao, V. Jakhmola

{"title":"Microsponge as Novel Drug Delivery System: A Review","authors":"Pratima Jayasawal, N. G. R. Rao, V. Jakhmola","doi":"10.35652/igjps.2022.12002","DOIUrl":"https://doi.org/10.35652/igjps.2022.12002","url":null,"abstract":"During the last few decades, pharmaceutical industry gave more importance to the controlled release of dosage forms like solid formulation, semi solid formulation, and topicalpreparation dueto efficacy and patient compliance. Normal topical preparations have some disadvantages like unpleasant odour, greasiness, and skin irritation reported in study cases. Also many topicalpreparations fail to reach the systemic circulation in sufficient amounts in few cases. This problem is achieved by the present formulation as microsponge in the areas of research. MDS is amicroscopic sphere capable of absorbing skin secretions, therefore reducing the oiliness of the skin. Microspongehaving particle size of 10-25 microns in diameter, have wide range of entrapmentof various ingredients in a single microsponges system and release them at desired rates.Microsponge is recent novel technique for control release and targetspecific drug delivery system. Microsponges are polymeric delivery system composed of porous microspheres. They are tiny sponge-like sphericalparticle with a large porous surface.Drug release in microsponge is done by the external stimuli like (pH, temperature, rubbing). It hasseveral advantageous over the other topical preparations are non allergenic, non toxic, non irritant, non mutagenic. Microsponges are designed to deliver apharmaceutical active ingredient efficiently at the minimum dose and alsoto enhance stability, reduce side effects and modify drug release.©2022iGlobal Research and PublishingFoundation. All rights reserved.","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73361205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Stability Study of Vata(Ficus bengalensisLinn.)Jata(Aerial Roots) Kwatha(Decoction) with Respect to Baseline Microbial Diagnostic Modalities 榕树(Ficus bengalensisLinn.)的稳定性研究芥(气根)瓜他(汤)与基线微生物诊断方式

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12004

Pravin Jawanjal, Cholera M.S., P. Bedarkar, B. Patagiri

{"title":"Stability Study of Vata(Ficus bengalensisLinn.)Jata(Aerial Roots) Kwatha(Decoction) with Respect to Baseline Microbial Diagnostic Modalities","authors":"Pravin Jawanjal, Cholera M.S., P. Bedarkar, B. Patagiri","doi":"10.35652/igjps.2022.12004","DOIUrl":"https://doi.org/10.35652/igjps.2022.12004","url":null,"abstract":"Background:Kwatha,one of the most popular Kalpanaamongst five basic Kalpana, is widely used therapeutically as well as pharmaceutically. Although a clear description is not available in Vedicliteraturewhereasa detailed description is available in all Samhitasregarding its preparation, the proportion of water to be added, reduction in the volume of liquid,etc.Aims:To check the stability of classical liquid dosage form, Vata(Ficus Bengalensis Linn.)Jata(aerial roots)Kwatha (decoction) with respect to its microbial profile. Materials and Methods:Sample of Vata Jata Kwatha wasprepared and studied to check microbial contamination at regular intervals. Results:Sixbatchesweresubjected to the microbiological study from the date of the preparation to the date of the last microbiological study. No,any contaminations were found in the microbiological study in a minimum of one day and a maximum of 7 days after the preparation of the sample. Discussion: Hence the present study was carried out to observe the stability study of Vata Jata Kwathawith respect to Microbial Contamination of the sample prepared and preserved in different climatic and temperature conditions. Thus, a baseline Microbial profile was studied at a regular interval.At the end of the study, it was found that the shelf life of Vata Jata Kwatha was varied as per humidity and temperature.Conclusion: In the microbiological study of Vata Jata Kwatha shows its stability in a minimum of one day and a maximumofseven days after the preparation of the sample.©2022iGlobal Research and PublishingFoundation. All rights reserved","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81692019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Polymers in the Design and Characterization of Sustained Release Aceclofenac Microspheres 高分子材料对乙酰氯芬酸缓释微球设计与表征的影响

Indo Global Journal of Pharmaceutical Sciences Pub Date : 2022-01-01 DOI: 10.35652/igjps.2022.12020

Pooja D. Vaghela

{"title":"Effect of Polymers in the Design and Characterization of Sustained Release Aceclofenac Microspheres","authors":"Pooja D. Vaghela","doi":"10.35652/igjps.2022.12020","DOIUrl":"https://doi.org/10.35652/igjps.2022.12020","url":null,"abstract":"Purpose:Theaim of present work was to design and characterize sustained release Aceclofenac, model drug, microspheres by emulsion solvent evaporation technique.Methods:Aceclofenac microspheres were prepared by emulsion solvent evaporation process by using Ethyl cellulose and Hydroxy propyl methyl cellulose as polymers. The microspheres were evaluated by drug release study, drug content, drug loading and encapsulation efficiency, and determination of percentage yield.Results:The present study shows that as the polymer concentration increases the percentage encapsulation efficiency, and drug content in the microsphere formulation also increases. The microspheres of all the formulated batches were spherical, discrete and free flowing. Increasing the polymer concentration in microsphere formulation decreases the rate of drug release dramatically.Conclusions:It might be concluded that drug loaded microspheres appear to be a suitable delivery system for a model drug, Aceclofenac, and may help to reduce dose of drug andfrequency of administration. Sustained release of Aceclofenac microspheres could be formulated by using ethyl cellulose and HPMC as a release retardant by emulsion solvent evaporation technique.©2022iGlobal Research and PublishingFoundation. All rights reserved","PeriodicalId":13366,"journal":{"name":"Indo Global Journal of Pharmaceutical Sciences","volume":"217 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76720737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0