Indian Dermatology Online Journal最新文献

{"title":"Reverse Isotopic Response: A Novel Phenomenon in Xeroderma Pigmentosum.","authors":"Febin Ashraf","doi":"10.4103/idoj.idoj_1292_24","DOIUrl":"https://doi.org/10.4103/idoj.idoj_1292_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Case of Scalp Actinomycosis.","authors":"Shreya K Gowda, Sonali Gupta, Poonam Singh, Dinesh P Asati","doi":"10.4103/idoj.idoj_886_24","DOIUrl":"https://doi.org/10.4103/idoj.idoj_886_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assisted Devices in Geriatric Dermatology and How to 'Roll' with It.","authors":"Sharad Mutalik, Shibhani S Hegde","doi":"10.4103/idoj.idoj_220_25","DOIUrl":"https://doi.org/10.4103/idoj.idoj_220_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lichen Planus Pemphigoides: A Clinical, Histopathological, and Immunological Report of 12 Indian Patients.","authors":"Dipankar De, Akash P Mustari, Debajyoti Chatterjee, Rahul Mahajan, Vinod Kumar, Sanjeev Handa","doi":"10.4103/idoj.idoj_763_24","DOIUrl":"10.4103/idoj.idoj_763_24","url":null,"abstract":"<p><strong>Background: </strong>Lichen planus pemphigoides (LPP) is a rare autoimmune subepidermal blistering disease presenting with lichenoid papules and plaques and tense blisters. There is a paucity of literature on LPP globally.</p><p><strong>Objective: </strong>To report the clinico-demographic profile, histopathology, immunological features, and associated comorbidities in LPP patients.</p><p><strong>Patients and methods: </strong>This was a retrospective study, where past records of all LPP patients diagnosed and treated between November 2013 and October 2022 were included. Patients having a compatible clinical presentation with histopathological and immunological (direct immunofluorescence) evidence of LPP were included.</p><p><strong>Results: </strong>There were 12 LPP patients, with a female-to-male ratio of 2:1. The mean age at diagnosis was 49.6 years and the mean duration of illness before presentation was 3.1 years. Clinical presentation included tense blisters and lichenoid lesions. Oral mucosal involvement was seen in six (50%) patients. Comorbidities were present in three patients. Histopathology showed a subepidermal split in 10 (83.3%), basal cell damage and pigment incontinence in four (33.3%), hypergranulosis and apoptotic keratinocytes in two (16.7%), and lichenoid infiltrate in papillary dermis in one (8.3%) patient. Perilesional direct immunofluorescence (DIF) revealed linear deposits of immunoglobulin G (IgG) and complement component 3 (C3) at the dermo-epidermal junction. The salt-split indirect immunofluorescence done in three patients showed roof binding. Enzyme-linked immunosorbent assay (ELISA) done in three patients showed antibodies against BP180. The majority of patients (83.3%) were treated with oral prednisolone, either alone (16.7%) or in combination (83.3%) with adjuvants.</p><p><strong>Limitations: </strong>Retrospective design and small sample size are the limitations.</p><p><strong>Conclusion: </strong>LPP is a rare subepidermal blistering disorder seen more commonly in adult females. DIF, ELISA, and salt-split indirect immunofluorescence are helpful tools in confirming the diagnosis of LPP and differentiating from bullous lichen planus. Oral corticosteroids comprised the mainstay of therapy. Azathioprine or dapsone were commonly used adjuvants.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"751-754"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Brief Review of Scalp Biopsy and its Interpretation.","authors":"Shreya K Gowda, Biswanath Behera, Madhusmita Sethy, Pavithra Ayyanar","doi":"10.4103/idoj.idoj_820_24","DOIUrl":"10.4103/idoj.idoj_820_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"785-791"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Trace Metal Imbalances: Serum Levels of Zinc, Selenium, Copper, Lead, Cadmium, and Mercury, and their Ratios in Acne Vulgaris Patients: An Analytical Cross-sectional Study.","authors":"Soumya Agarwal, Shivani Singh, Sonal Singh, Vandana Tiwari, Vikram Singh","doi":"10.4103/idoj.idoj_954_24","DOIUrl":"10.4103/idoj.idoj_954_24","url":null,"abstract":"<p><strong>Background: </strong>Acne vulgaris is one of the most problematic skin disorders among young adults with evolving etiopathogenesis. The study aimed to determine the correlation between serum levels of copper (Cu), zinc (Zn), selenium (Se), lead (Pb), mercury (Hg), cadmium (Cd), and Cu/Pb, Cu/Hg, Cu/Cd, Cu/Se, and Cu/Zn ratios in patients of acne vulgaris.</p><p><strong>Patients and methods: </strong>In our study, we enrolled 139 acne vulgaris patients as cases and 86 normal adults as controls. Using the global acne grading system (GAGS score), these cases were categorized into mild (n 1 = 32), moderate (n 2 = 82), and severe (n 3 = 25). Venous blood samples of all study participants (aged 15-25 years) were examined for serum levels of zinc, copper, selenium, lead, mercury, and cadmium using inductively coupled plasma mass spectrometry (ICPMS). SPSS.21 version software was used for the analysis of data.</p><p><strong>Results: </strong>We noted statistically significant ( P value < 0.001, student's t test) difference in mean serum levels of Cu, Zn, Se, Pb, and Hg (microgram/liter) between cases and controls denoted as 2773.60 ± 1234.45 vs.1672.10 ± 696.70, 904.19 ± 644.48 vs.1621.50 ± 554.80, 175.24 ± 88.96 vs.292.86 ± 119.39, 0.84 ± 0.18 vs.0.10 ± 0.02, 2.61 ± 0.42 vs.1.99 ± 0.72, respectively. Serum Cd was undetectable in all the study participants. Low levels of serum Cu, and Cu/Se ratio and high levels of Pb, Hg, Cu/Hg, and Cu/Pb ratios were associated with the severity of acne vulgaris ( P value < 0.001). A significantly low Cu/Zn ratio was observed in cases compared to controls.</p><p><strong>Limitations: </strong>Small sample size and non-assessment of the method of cooking.</p><p><strong>Conclusion: </strong>Low levels of Zn and Se, and high levels of Pb and Hg could play a crucial role in the etiopathogenesis of acne, especially in moderate to severe cases. Copper, which, although elevated overall in acne cases, was found to be lower in severe cases compared to mild and moderate cases.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"725-731"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimizing the Dermatological Consequences of Exposure to E-waste.","authors":"Saurabh RamBihariLal Shrivastava, Prateek Sudhakar Bobhate, Sudhir Singh, Sabiha Quazi, Sugat Jawade","doi":"10.4103/idoj.idoj_128_25","DOIUrl":"10.4103/idoj.idoj_128_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 5","pages":"882-884"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disseminated Molluscum Contagiosum Treated with Cidofovir in a 16 Year Old with Acute Lymphoblastic Leukemia.","authors":"Deepthy Sara Sen, Sebastian Criton, A K Adarsh","doi":"10.4103/idoj.idoj_216_24","DOIUrl":"10.4103/idoj.idoj_216_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"850-851"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Huriez Syndrome.","authors":"Sonal Singh, Sudip Das","doi":"10.4103/idoj.idoj_523_24","DOIUrl":"10.4103/idoj.idoj_523_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"815-816"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morpheaform Sarcoidosis - A Very Rare Presentation of Sarcoidosis with a Brief Review of Literature.","authors":"Cinderella Xson, S Pradeep Nair, T Kabilan","doi":"10.4103/idoj.idoj_596_24","DOIUrl":"10.4103/idoj.idoj_596_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"854-856"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}