Indian Journal of Pharmacy and Pharmacology最新文献_第9页

Estimation of phytochemicals contents and in-vitro antioxidant activity of Opuntia ficus Indica fruit extract 无花果果实提取物植物化学物质含量及体外抗氧化活性的研究

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-07-15 DOI: 10.18231/j.ijpp.2022.015

Krati Sharma, R. Malviya, V. Gupta

引用次数: 0

Ecopharmacovigilance: Need of the hour 生态药物警戒:时势之需

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-07-15 DOI: 10.18231/j.ijpp.2022.014

Avisek Dutta, Anupam Banerjee, S. Chaudhry

{"title":"Ecopharmacovigilance: Need of the hour","authors":"Avisek Dutta, Anupam Banerjee, S. Chaudhry","doi":"10.18231/j.ijpp.2022.014","DOIUrl":"https://doi.org/10.18231/j.ijpp.2022.014","url":null,"abstract":"Pharmaceuticals in the environment have the potential to be hazardous to human beings. With each passing day it is becoming a major source of concern. Due to recent findings showing the availability of pharmaceutical components in the environment, particularly in ground water bodies, pharmaceuticals have gained a growing amount of attention from worldwide health regulatory bodies and have become one of the most significant water pollutants. The aim of this article is to review the environmental hazards of pharmaceuticals that have been reported in various literature sources to promote awareness on safe usage of medicines, to increase pharmaceutical manufacturers’ knowledge on environmental safety aspects and to arrest the attention of pharmacovigilance practitioners to some of the emerging problems caused by medicines. Pharmaceutical waste has been a source of huge concern amongst environmental scientists. Pharmaceutical manufacturers and pharmacovigilance scientists should invest more attention to these increasing environmental concerns caused by medications. Ecopharmacovigilance is defined by the World Health Organization (WHO) as the science and activities concerned with the detection, assessment, understanding, and prevention of adverse events or other related problems caused by pharmaceuticals in the environment that affect people and other animal species. This review is an attempt to compile information on Ecopharmacovilance, with an emphasis on the Indian perspective.","PeriodicalId":13313,"journal":{"name":"Indian Journal of Pharmacy and Pharmacology","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90863935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transdermal patches of Aegle Marmelos leaves for the management of diabetes 用于治疗糖尿病的鹿茸叶透皮贴片

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-07-15 DOI: 10.18231/j.ijpp.2022.020

C. Singh, Amit Kumar

引用次数: 0

Anthelmintic activity of (Mugwort) extracted with ethanol and rice gruel solvents 乙醇和米粥溶剂提取艾草的驱虫活性

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-07-15 DOI: 10.18231/j.ijpp.2022.016

A. Badarinath, S. Sreenivas, Chepuri Madhavi, Kontham Sadhana, Gundeboina Swathi, Y. Sreelatha

{"title":"Anthelmintic activity of (Mugwort) extracted with ethanol and rice gruel solvents","authors":"A. Badarinath, S. Sreenivas, Chepuri Madhavi, Kontham Sadhana, Gundeboina Swathi, Y. Sreelatha","doi":"10.18231/j.ijpp.2022.016","DOIUrl":"https://doi.org/10.18231/j.ijpp.2022.016","url":null,"abstract":"This laboratory study was carried out to explore the anthelmintic properties of (Mugwort) extracts aligned with Indian earthworms Alcoholic extract and Rice Gruel extract of leaves were used as test. Albendazole was incorporated as standard drug and normal saline as control. Observations were made for the time taken to paralyze and death of the earthworm. Three concentrations 30, 60, 100mg/ml of every extract and standard drug at the concentration of 30mg/ml were studied. The outcome of study indicated that rice gruel extract of exhibited anthelmintic activity significantly higher than standard and also in a dose dependent manner. For the ethanolic extract group the time of paralysis and death time was 3.38 minute and 13.82 minute, while rice gruel extract group showed shortest time of paralysis (P) at 2.12 minute and death (D) at 7.45 minute of earthworms at higher concentration 100mg/ml as compared to standard Albendazole (30mg/ml) paralysis 2.27 minute and death at 6.44 minute respectively. Rice gruel extract showed more pronounced effect than ethanolic extract. Whereas the control group worms were observed for full day and night and there was no paralysis or death was found during that period.","PeriodicalId":13313,"journal":{"name":"Indian Journal of Pharmacy and Pharmacology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72915336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

To study the incidences of needle stick injury among critical care nurses working in rural tertiary care hospital 目的了解农村三级医院危重病护理人员针刺伤发生率

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-07-15 DOI: 10.18231/j.ijpp.2022.022

A. Shetti, Ishita Deshpande, Bhavika Singla, Rachita G Mustilwar

{"title":"To study the incidences of needle stick injury among critical care nurses working in rural tertiary care hospital","authors":"A. Shetti, Ishita Deshpande, Bhavika Singla, Rachita G Mustilwar","doi":"10.18231/j.ijpp.2022.022","DOIUrl":"https://doi.org/10.18231/j.ijpp.2022.022","url":null,"abstract":"Needle-stick injuries (NSIs) are a hazard for nursing staff and public health. Nursing workers are at high risk for occupational exposure to blood-borne pathogens via sharp injuries of the needle-stick. Needle-stick injuries (NSIs) are described as penetrating wounds caused by a device that is contaminated with another person’s body fluids. Needle-stick injuries are injuries acquired by needles like -scalp vein needles, hypodermic needles, blood sample collection needles, intracath stylets, lumbar puncture needles used to connect parts of IV delivery systems. Needle-stick injuries (NSIs) form a medium for the transmission of bloodborne infections. Strict use of personnel protective equipment while working in the hospital should be made compulsory. To study incidences of needle stick injury among nurses working in Rural tertiary care Unit, Loni. Ethical approval for this study was obtained from the Institutional Ethical Committee. Seventy-six nurses, who fulfilled inclusion criteria were included and data was obtained through survey. This study involves 76 nursing staff. Of them all, 27(35.5%) nursing staff experienced NSIsThe administration of medication was common action that caused most of needle-stick injuries mentioned by 14 (18.4%) nursing staff. IV cannula was the device that caused many needle-stick injuries reported by 17 (21.1%) nursing staff. Thenursing professionals are the main key players in both elective and emergency situations. There is a quite higher incidence of needle stick injury among critical care nurses. This might be due to handling of emergency cases and attempting to secure the intravenous line or to deliver the medications. Creating awareness and training appropriately is mandatory for critical care nurses.","PeriodicalId":13313,"journal":{"name":"Indian Journal of Pharmacy and Pharmacology","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84586150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of short term effects of first and second dose COVID-19 vaccination among critical care nurses in rural tertiary care hospital 农村三级医院危重护理护士第一次和第二次新冠肺炎疫苗接种短期效果评价

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-07-15 DOI: 10.18231/j.ijpp.2022.023

D. D. Patel, Bhavika Singla

{"title":"Evaluation of short term effects of first and second dose COVID-19 vaccination among critical care nurses in rural tertiary care hospital","authors":"D. D. Patel, Bhavika Singla","doi":"10.18231/j.ijpp.2022.023","DOIUrl":"https://doi.org/10.18231/j.ijpp.2022.023","url":null,"abstract":"The Corona virus disease 2019 is a contagious disease caused by severe acute respiratory syndrome coronavirus 2. The disease has since spread worldwide, leading to an ongoing pandemic. The attitude and knowledge of health care specialists towards vaccination is very important. Hence we conducted a study among critical care nurses.This cross sectional study is conducted among 76 adult critical care unit nurses who received Covishield vaccine. The survey included 13 questions.Post first dose of vaccination Out of 76 critical care nurse, 49 (64.5%) were males and 27 (35.5%) were females. 42(55.3%) nurses were posted for covid duty while 34( 44.7%) were never posted for covid duty, among these all 31( 40.8%) were suffered with covid infection before vaccination. Post first dose of COVID 19 vaccination, 65(85.5%) nurses developed symptoms while 11 (14.5%) were asymptomatic.Post second dose of vaccination; Out of Out of 76 critical care nurses participated in the study, 50 (66%) were males and 26 (34%) were females. 42(55%) nurses were posted for covid duty while 34 (45%) were never posted for covid duty. Among all critical care nurses 31 (40.8%) were diagnosed with COVID 19 positive before vaccination while 45(59.2%) were found to be COVID negative. Post second dose of COVID 19 vaccination, 50(66%) nurses developed symptoms while 26(34%) were asymptomatic.Based on our study the side effects are present with covishield vaccine. Nurses are willing to take booster dose and to promote vaccination too.","PeriodicalId":13313,"journal":{"name":"Indian Journal of Pharmacy and Pharmacology","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77622441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of angiotensin converting enzyme gene polymorphism with diabetic nephropathy in patients using lisinopril 血管紧张素转换酶基因多态性与赖诺普利患者糖尿病肾病的关系

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-07-15 DOI: 10.18231/j.ijpp.2022.018

Hammad Ullah, A. Razaq, S. Altaf, T. Basharat, S. Tariq, Sami Siraj, A. Azhar, Waheed lqbal, Haroon Khan

{"title":"Association of angiotensin converting enzyme gene polymorphism with diabetic nephropathy in patients using lisinopril","authors":"Hammad Ullah, A. Razaq, S. Altaf, T. Basharat, S. Tariq, Sami Siraj, A. Azhar, Waheed lqbal, Haroon Khan","doi":"10.18231/j.ijpp.2022.018","DOIUrl":"https://doi.org/10.18231/j.ijpp.2022.018","url":null,"abstract":"Angiotensin Converting Enzyme (ACE) plays an important role in the development and progression of Diabetic nephropathy (DN). The present study was designed to determine the possible association between ACE gene polymorphism and DN. The study included 242 samples: DN (n = 121), type 2 Diabetes mellitus (DM2) (n = 60) and control (n = 61). The blood samples were collected from the subjects, followed by DNA extraction. Insertion deletion polymorphism of ACE gene studied using specific primers. Patients using Lisinopril were followed for two months. The ACE genotype distribution in DN patients was as follows: DD (n = 47; 38.84%), II (n = 17; 14.04%) and DI (n = 57; 47.10%). In DM group the genotype distribution was DD (n = 4; 6.66%), II (n = 25; 41.66%) and DI (n = 31; 51.66%) while in control group DD (n = 38; 62.29%), II (n = 1; 1.63%) and DI (n = 22; 36.06%). The comparison of II genotype to DD genotype was reflected by p-value =0.0001, OR=17.28 and 95% CI 5.313-49.58. The percent decrease of micro-albuminuria after two months with the use of Lisinopril 10 mg twice a day in DD, II and DI genotype of DN were 31.27%, 12.37% and 16.81%, respectively. Our findings revealed that DD genotype has strong association with DN but not a risk factor for development of disease.","PeriodicalId":13313,"journal":{"name":"Indian Journal of Pharmacy and Pharmacology","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90935651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Important medicinal plants for management of psoriasis 治疗牛皮癣的重要药用植物

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-07-15 DOI: 10.18231/j.ijpp.2022.021

F. Tamboli, P. Kokate, Arbaz Rahimoddin Shaikh, Anilkumar Jalinder Shinde, A. Namdeo, K. Alaskar

引用次数: 0

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome induced by ceftriaxone with successful treatment — A case report and literature review 头孢曲松治疗成功致嗜酸性粒细胞增多及全身症状(DRESS)综合征的药物反应1例报告并文献复习

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-15 DOI: 10.18231/j.ijpp.2021.053

Arpit Agrawal, P. Kannauje

引用次数: 0

Students’ perception on online learning during COVID pandemic in a tertiary care teaching hospital 某三级医疗教学医院新冠疫情期间学生对在线学习的看法

Indian Journal of Pharmacy and Pharmacology Pub Date : 2022-01-15 DOI: 10.18231/j.ijpp.2021.051

Kranti Tekulapally

{"title":"Students’ perception on online learning during COVID pandemic in a tertiary care teaching hospital","authors":"Kranti Tekulapally","doi":"10.18231/j.ijpp.2021.051","DOIUrl":"https://doi.org/10.18231/j.ijpp.2021.051","url":null,"abstract":"Medical and Dental students are exposed to online classes for the first time during the COVID pandemic. The current study was planned to understand their perceptions about these online classes in contrast to classroom teaching and suggest strategies to improve them.A cross-sectional study was carried out among all the students of Malla Reddy Medical College for Women and Malla Reddy Dental College for Women during September 2020. The study questionnaire containing 20 questions was prepared, prevalidated and distributed to all the study participants as google form. Data from completed questionnaires was entered into an excel sheet and analyzed using descriptive statistics.Analysis of data from 279 students revealed that the 69% of the students used smartphones to attend online classes, 96% of them reported having internet problems and 42% of the students enjoyed the online classes. Understanding of the topic and knowledge gained during online classes were rated average and above average by 59% and 53% of the students respectively. Many students felt that long screen hours have made the classes less interesting and caused health issues like headaches, eyestrain, and backache. They also felt that online classes were less interactive and did not provide much clinical and practical knowledge.Students showed a negative response to online classes. There is a need to make online classes more interactive and interesting by using certain strategies like problem-solving activities, quizzes, discussions, surveys, and polls. Faculty should be trained in good online teaching practices to ensure its success.","PeriodicalId":13313,"journal":{"name":"Indian Journal of Pharmacy and Pharmacology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78523829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0