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Refractory Metastatic Vulvar Crohn's Disease Mimicking Tuberculosis. 难治性转移性外阴克罗恩病模拟结核。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-04 DOI: 10.1007/s13312-025-00031-7
Vaibhav S Bellary, Jitendra S Oswal
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引用次数: 0
Utility of Fecal Biomarkers to Predict Invasive Nature of Acute Infectious Diarrhea in Indian Children. 粪便生物标志物在预测印度儿童急性感染性腹泻侵袭性方面的实用性
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-04 DOI: 10.1007/s13312-025-00030-8
Prabhav Aggarwal, Raghvendra Singh, Masoom Nathani, Sonal Saxena, Oves Siddiqui
{"title":"Utility of Fecal Biomarkers to Predict Invasive Nature of Acute Infectious Diarrhea in Indian Children.","authors":"Prabhav Aggarwal, Raghvendra Singh, Masoom Nathani, Sonal Saxena, Oves Siddiqui","doi":"10.1007/s13312-025-00030-8","DOIUrl":"https://doi.org/10.1007/s13312-025-00030-8","url":null,"abstract":"<p><strong>Objective: </strong>To determine role of fecal calprotectin (FC) and fecal lactoferrin (FL) in diagnosis of invasive diarrhea.</p><p><strong>Methods: </strong>Stool samples from 75 children (≤ 12 years) with acute diarrhea were analysed using wet mount microscopy, culture, multiplex polymerase chain reaction, rapid tests for Rotavirus/ Adenovirus and quantitative ELISA for FC and FL.</p><p><strong>Results: </strong>The mean (SD) FC levels (μg/g) [774 (626.59) vs. 213 (251.48), P < 0.001] and FL levels (μg/g) [7.95 (4.72) vs. 4.22 (3.91), P = 0.004] were significantly higher in children with invasive diarrhea (n = 38) compared to those with non-invasive diarrhea (n = 37). Cut-off values of FC > 243 μg/g (sensitivity 81.57%, specificity 67.56%, AUC 0.813) and for FL > 6.02 μg/g (sensitivity 71.05%, specificity 81.08%, AUC 0.732) have diagnostic potential.</p><p><strong>Conclusions: </strong>FC and FL can aid diagnosis of acute invasive diarrhea.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reforming Medical Education to Address the Challenge of Professional Identity for Medical Students. 改革医学教育应对医学生职业认同的挑战。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-01 Epub Date: 2025-03-28 DOI: 10.1007/s13312-025-00054-0
Hongnan Ye
{"title":"Reforming Medical Education to Address the Challenge of Professional Identity for Medical Students.","authors":"Hongnan Ye","doi":"10.1007/s13312-025-00054-0","DOIUrl":"10.1007/s13312-025-00054-0","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"318-319"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Chloride Diarrhea in Infancy: Unveiling a Rare Clinical Case. 婴儿先天性氯化物腹泻：揭示一个罕见的临床病例。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1007/s13312-025-00041-5
P N V Sneharika, Mukesh Kumar Jain, Sibabratta Patnaik, Parthasarathy Lall
{"title":"Congenital Chloride Diarrhea in Infancy: Unveiling a Rare Clinical Case.","authors":"P N V Sneharika, Mukesh Kumar Jain, Sibabratta Patnaik, Parthasarathy Lall","doi":"10.1007/s13312-025-00041-5","DOIUrl":"10.1007/s13312-025-00041-5","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"293-294"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Levofloxacin Preventive Therapy for Children Living with Adults with MDR-TB: Evidence-Based Medicine Viewpoint. 左氧氟沙星预防治疗与耐多药结核病成人一起生活的儿童：循证医学观点。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00069-7
Joseph L Mathew
{"title":"Levofloxacin Preventive Therapy for Children Living with Adults with MDR-TB: Evidence-Based Medicine Viewpoint.","authors":"Joseph L Mathew","doi":"10.1007/s13312-025-00069-7","DOIUrl":"10.1007/s13312-025-00069-7","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"306-309"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simplifying Strategies to Enable Universal, Decentralized Cord Blood TSH Screening: Lessons from a Tertiary Care Center in North India. 简化策略以实现普遍、分散的脐带血TSH筛查：来自印度北部三级保健中心的经验教训。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-01 Epub Date: 2025-03-14 DOI: 10.1007/s13312-025-00003-x
Dhruv Singh Gaur, Varun Vij, Anju Virmani, Ganesh Jevalikar, Manish Malik
{"title":"Simplifying Strategies to Enable Universal, Decentralized Cord Blood TSH Screening: Lessons from a Tertiary Care Center in North India.","authors":"Dhruv Singh Gaur, Varun Vij, Anju Virmani, Ganesh Jevalikar, Manish Malik","doi":"10.1007/s13312-025-00003-x","DOIUrl":"10.1007/s13312-025-00003-x","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the utility of cord blood thyroid stimulating hormone (CBTSH) for improving the universal newborn screening (UNBS) strategy, and  to generate regional normative data.</p><p><strong>Methods: </strong>Data of UNBS using CBTSH and cord blood free thyroxine (CBfT4) over two years (01 April 2022 to 31 March 2024) in all inborn deliveries was analyzed using descriptive statistics.</p><p><strong>Results: </strong>Out of 2218 neonates delivered to 2094 mothers, data was available for 2116 newborns (54.4% males; 68.2% term gestation; 27%, 3.5%, and 0.9% late, early and extreme preemies, respectively; 61% appropriate-for-gestational age). The mean (SD) CBTSH was 7 (5.3) mIU/L (3rd-97th percentiles: 2.6-18.8 mIU/ml); higher in extreme preterms, extremely low birth weight (< 1000 g) and sick babies. Mean (SD) cord blood free thyroxine (CBfT4) was 0.99 (0.2) ng/dL (3rd-97th percentiles: 0.7-1.4 ng/dL), lower in extreme preterms. 58 newborns (recall rate 2.7%) had CBTSH > 20 mIU/L (all had normal CBfT4) and were recalled: 5 did not return, 52/53 were normal on retesting. Only 2/58 newborns had CBTSH > 40 mIU/L: one had confirmed CH. With CBTSH cutoff > 40 mIU/L, recall rate could have been reduced to 0.09%.</p><p><strong>Conclusion: </strong>We propose simplified screening strategies of \"retest and recall\", and using three CBTSH categories, i.e., (a) < 20 mIU/L: normal, discharge; (b) 20-40 mIU/L: test CBfT4, if < 0.7 ng/dL, do confirmatory venous TSH & fT4 at 72 h age (before discharge); (c) > 40 mIU/L: confirmatory venous TSH & fT4 at 72 h (before discharge): if venous TSH < 20 mIU/L: normal; TSH 20-40 mIU/L or fT4 < 0.7 ng/dL: recall and retest at 7-10 days age. If confirmatory venous TSH is high or fT4 is low, start replacement. This would improve decision-making and minimize burden of unnecessary recalls while ensuring early identification.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"276-282"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breaking the Chains of Childhood Obesity. 打破儿童肥胖的枷锁。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00070-0
Vasant Khalatkar
{"title":"Breaking the Chains of Childhood Obesity.","authors":"Vasant Khalatkar","doi":"10.1007/s13312-025-00070-0","DOIUrl":"10.1007/s13312-025-00070-0","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"259"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum: Transcranial Doppler: The Bedside Window to Explore Cerebral Hemodynamics. 勘误：经颅多普勒：探索脑血流动力学的床边窗口。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00074-w
Muthu Chidambaram
{"title":"Erratum: Transcranial Doppler: The Bedside Window to Explore Cerebral Hemodynamics.","authors":"Muthu Chidambaram","doi":"10.1007/s13312-025-00074-w","DOIUrl":"10.1007/s13312-025-00074-w","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"323"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcranial Doppler: The Bedside Window to Explore Cerebral Hemodynamics. 经颅多普勒：探索脑血流动力学的床边窗口。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00011-x
Muthu Chidambaram
{"title":"Transcranial Doppler: The Bedside Window to Explore Cerebral Hemodynamics.","authors":"Muthu Chidambaram","doi":"10.1007/s13312-025-00011-x","DOIUrl":"10.1007/s13312-025-00011-x","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"260-261"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clippings: Pediatric Neurology. 剪报：儿科神经病学。
IF 1.7 4区 医学
Indian pediatrics Pub Date : 2025-04-01 DOI: 10.1007/s13312-025-00056-y
Indar Kumar Sharawat
{"title":"Clippings: Pediatric Neurology.","authors":"Indar Kumar Sharawat","doi":"10.1007/s13312-025-00056-y","DOIUrl":"10.1007/s13312-025-00056-y","url":null,"abstract":"","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"321-322"},"PeriodicalIF":1.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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