Indian Journal of Medical Microbiology最新文献_第2页

Malaria a culprit of Gullian Barre Syndrome (GBS): A case report

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-15 DOI: 10.1016/j.ijmmb.2025.100824

Sara Soomro, Mehmood Alam, Hiba Akber, Sara Ismail, Lubna Iqbal Abbasi, Fivzia Farooq Herekar

引用次数: 0

Kimura disease with Nocardiosis in a child with a novel mutation in IL12RB1gene 一名患有新型 IL12RB1 基因突变的儿童患上木村病并伴有诺卡氏菌病。

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100816

Kranthikumar Karrolla , Gayatri Karuthapandy , Jaikumar Govindaswamy Ramamoorthy , Venkatesh Chandrasekaran , Gunasekaran Dhandapany , Maanasa Bhaskar , Mahalakshmi Kumaresan

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Short-term storage of Candida auris in resource-limited setting

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100823

Yağmur Ekenoğlu Merdan, Kaan Zıkşahna

引用次数: 0

Unleashing the potent synergy of ceftazidime-avibactam and aztreonam against metallo-beta-lactamase producing Enterobacterales in the battle against antibiotic resistance. An in vitro study

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100819

Madhu Rai , Shaoli Basu , Priti Kambli , Lizanne Drego , Priyanka Patel , Anjali Shetty , Camilla Rodrigues

引用次数: 0

Laboratory diagnosis of pleural tuberculosis: An unsolved enigma

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100817

Atish Mohapatra , Ujjwala Gaikwad , Ranganath T. Ganga , Pratibha Sharma

{"title":"Laboratory diagnosis of pleural tuberculosis: An unsolved enigma","authors":"Atish Mohapatra , Ujjwala Gaikwad , Ranganath T. Ganga , Pratibha Sharma","doi":"10.1016/j.ijmmb.2025.100817","DOIUrl":"10.1016/j.ijmmb.2025.100817","url":null,"abstract":"<div><h3>Background</h3><div>Pleural Tuberculosis (TB) diagnosis is challenging and the current diagnostic approach is multidisciplinary involving clinico-radiological methods in addition to laboratory parameters. The study aims to explore the role of all available parameters for pleural TB diagnosis.</div></div><div><h3>Methods</h3><div>A cross-sectional study on suspected pleural TB patients was conducted at a tertiary care hospital in Chhattisgarh from February to November 2021. After obtaining consent and clinico-radiological information, pleural fluid was collected and tested for biochemical profile and detection of <em>Mycobacterium tuberculosis</em> using available microbiological parameters.</div></div><div><h3>Results</h3><div>Out of 170 subjects, 26 had Definite TB (Microbiologically confirmed), 22 had Probable TB (clinico-radiologically confirmed), and 122 had No-TB. Necrotizing mediastinal lymphadenopathy, cervical lymphadenopathy & loculated effusion were significant radiological findings. Amongst biochemical parameters, (Receiver Operating Characteristic (ROC) cut off 40.0 U/L; AUC = 0.889) of Adenosine Deaminase (ADA) was proved to be a better biomarker than LDH (ROC cut off 442.0 IU/L; AUC = 0.645). Out of all available microbiological parameters, Cartridge Based Nucleic Acid Amplification Test (CBNAAT) performed better by identifying (6/7; 85.71 %) pleural TB cases when compared against Microbiological Reference Standards (MRS). While compared against Composite Reference Standards (CRS), Mycobacteria Growth Indicator Tube (MGIT) performed better than other microbiological parameters by identifying (19/48; 39.5 %), while both CBNAAT and Truenat could identify (6/16; 37.5 %) and (12/32; 37.5 %) respectively.</div></div><div><h3>Conclusion</h3><div>In association with clinical and radiological features, ADA estimation is quite helpful in establishing or refuting the diagnosis of microbiologically negative pleural tuberculosis.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100817"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the uncommon: A rare case report of osteomyelitis caused by Enterococcus avium 揭开不常见的面纱：由肠球菌引起骨髓炎的罕见病例报告。

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100818

Priya Sreenivasan , Rishin Raj , J. Kumaravel , Deepak Kumar , Archana Angrup

引用次数: 0

Sebaceous nevus affected by overgrowth of Malassezia restricta 受马拉色菌过度生长影响的皮脂腺痣。

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100812

Ying Huang , Sushmita Pradhan , Yuping Ran

引用次数: 0

Silent escalation: The journey of Shigella from gut to blood

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100815

Ekadashi Rajni , Snigdha Purohit , Rachna Priyadarshini , Gunjan Agarwal

引用次数: 0

Navigating the molecular landscape of Candida auris in a tertiary care setting in Eastern India

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100814

Pritika Gahlot , Vinaykumar Hallur , Bijayini Behera , Prashanth Purushotham , Diptanu Paul , Jawahar Pillai , Swagata Tripathy , Anupam Dey , Krishna Mohan Gulla , Madhuchhanda Das , Shivaprakash M. Rudramurthy

{"title":"Navigating the molecular landscape of Candida auris in a tertiary care setting in Eastern India","authors":"Pritika Gahlot , Vinaykumar Hallur , Bijayini Behera , Prashanth Purushotham , Diptanu Paul , Jawahar Pillai , Swagata Tripathy , Anupam Dey , Krishna Mohan Gulla , Madhuchhanda Das , Shivaprakash M. Rudramurthy","doi":"10.1016/j.ijmmb.2025.100814","DOIUrl":"10.1016/j.ijmmb.2025.100814","url":null,"abstract":"<div><h3>Purpose</h3><div><em>Candida auris</em> was recently listed as a critical priority fungal pathogen by WHO due to its multidrug resistance and enhanced propensity for nosocomial transmission. This study investigated the molecular epidemiology and colonization patterns of <em>C. auris</em> in a tertiary care center in Eastern India.</div></div><div><h3>Methods</h3><div>A total of 201 patients from different intensive care units (ICUs) were enrolled, with colonization rates determined through enrichment followed by culture on chromogenic agar and molecular confirmation using <em>Candida auris</em> specific polymerase chain reaction (PCR) and antifungal susceptibility testing was done using microbroth dilution. For molecular characterization Fluorescent Amplified Fragment Polymorphism (FAFLP) was used.</div></div><div><h3>Results</h3><div>FAFLP revealed multiple clusters of strains, predominantly belonging to clade I, with notable isolates closely associated with clades III, IV, and V, previously unreported in India. Antifungal susceptibility testing found high resistance to amphotericin B (59.6 %) and low resistance to fluconazole compared to older studies (59.6 %), underscoring the need for further investigation. Sustained transmission of <em>C. auris</em> was observed despite infection control measures, emphasizing the ongoing challenges in infection control and the necessity for continuous surveillance.</div></div><div><h3>Conclusion</h3><div>This study contributes valuable insights into the epidemiology and genetic diversity of <em>C. auris</em> in Eastern India, highlighting the need for further investigations to understand transmission dynamics and clinical implications and underscores the importance of ongoing surveillance in combating this emerging pathogen.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100814"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular characterization of methicillin-resistant Staphylococcus aureus: Dissemination of multidrug-resistant community-associated MRSA and emergence of LA-MRSA, in a healthcare setting

IF 1.4 4区医学

Indian Journal of Medical Microbiology Pub Date : 2025-02-25 DOI: 10.1016/j.ijmmb.2025.100810

Vijayan Priya, S. Nagarathna, Kumari HB. Veena

{"title":"Molecular characterization of methicillin-resistant Staphylococcus aureus: Dissemination of multidrug-resistant community-associated MRSA and emergence of LA-MRSA, in a healthcare setting","authors":"Vijayan Priya, S. Nagarathna, Kumari HB. Veena","doi":"10.1016/j.ijmmb.2025.100810","DOIUrl":"10.1016/j.ijmmb.2025.100810","url":null,"abstract":"<div><h3>Background</h3><div>Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) continues to be a significant cause of healthcare-associated infections (HAIs). In this study, we aimed to characterize the MRSA isolates obtained from HAIs.</div></div><div><h3>Methods</h3><div>A total of 200 clinical and 13 nasal MRSA isolates were collected and tested. The samples were analyzed for SCC<em>mec</em> typing by using multiplex PCR. Microtiter for biofilm formation were performed and molecular typing for the samples were performed for spa and agr typing.</div></div><div><h3>Results</h3><div>The isolates showed 100 % sensitivity to vancomycin and linezolid, while 92.5 % were multidrug-resistant. Strong biofilm-forming ability was observed in 47 % of the isolates. SCC mec typing identified 52.5 % of the isolates as classical hospital-associated MRSA or HA-MRSA (SCC mec type III), 23.5 % as community-associated MRSA or CA-MRSA (type IV and V), and 16.5 % as non-typeable, with 7.5 % having multiple SCCmec types.</div></div><div><h3>Conclusion</h3><div>Comparison of HA and CA-MRSA traits revealed that both groups had multidrug resistance, but HA-MRSA was distinguished by its strong capacity for biofilm formation, whereas CA-MRSA was marked by a high count of toxin gene. Our study, to the best of our awareness, documents the presence of LA-MRSA (SCCmec V- t127-agr III) causing HAIs in Indian patients for the first time.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100810"},"PeriodicalIF":1.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0