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Machine Learning-Based Prediction of Drug-Resistant Epilepsy 基于机器学习的耐药癫痫预测
Epilia: Epilepsy and Community Pub Date : 2021-09-30 DOI: 10.35615/epilia.2021.00298
Y. Shin, Heesang Eum, Kwang Su Cha, Ki-Young Jung
{"title":"Machine Learning-Based Prediction of Drug-Resistant Epilepsy","authors":"Y. Shin, Heesang Eum, Kwang Su Cha, Ki-Young Jung","doi":"10.35615/epilia.2021.00298","DOIUrl":"https://doi.org/10.35615/epilia.2021.00298","url":null,"abstract":"data from used a a convolutional neural network, a temporal convolutional network to learn the EEG patterns of patients with drug-resistant epilepsy. Data from 978 EEG examinations were available for training and testing. best performance an accuracy of of Our models predicted drug-resistant epilepsy better than drug-sensitive epilepsy. that EEG contain information predictive of epilepsy; the performance of the current model insufficient for clinical use to predict drug-resis-tant epilepsy. Our findings warrant further investigation to identify EEG markers of drug-resistance and to increase model performance to a level sufficient to aid in clinical decision-making.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"402 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126673503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possible Effect of Perampanel on Epilepsia Partialis Continua after Generalized Tonic-Clonic Status Epilepticus 泛强直-阵挛性癫痫持续状态后，Perampanel对部分持续性癫痫的可能影响
Epilia: Epilepsy and Community Pub Date : 2021-09-30 DOI: 10.35615/epilia.2021.00291
Tae-won Yang, Do-Hyung Kim, Young-Soo Kim
{"title":"Possible Effect of Perampanel on Epilepsia Partialis Continua after Generalized Tonic-Clonic Status Epilepticus","authors":"Tae-won Yang, Do-Hyung Kim, Young-Soo Kim","doi":"10.35615/epilia.2021.00291","DOIUrl":"https://doi.org/10.35615/epilia.2021.00291","url":null,"abstract":"amino-3-hydroxy-5-meth-Epilepsia defined a syndrome of a of is approved antiepileptic and generalized epilepsy and has a distinct and selective mode of action on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepro-pionic acid receptors. There are also anecdotal reports on its use in status epilepticus. Herein, present a case where was the last antiepileptic drug introduced for the treatment of EPC before its termination 48 hours later. PER might be a safe choice that can be considered as an additional option for patients with The effect of PER on various of in seizure-controlling","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121324899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Felt Stigma in Korean Persons with Epilepsy 韩国癫痫患者感到耻辱
Epilia: Epilepsy and Community Pub Date : 2021-09-30 DOI: 10.35615/epilia.2021.00256
Sang-Ahm Lee
{"title":"Felt Stigma in Korean Persons with Epilepsy","authors":"Sang-Ahm Lee","doi":"10.35615/epilia.2021.00256","DOIUrl":"https://doi.org/10.35615/epilia.2021.00256","url":null,"abstract":"The presence of felt stigma has considerable impacts on psychological well-being, including depression, anxiety, and poor health-related quality of life. These findings may provide a basis for further studies to clarify the causative factors generating felt stigma and to develop potential therapeutic interventions for felt stigma of epilepsy. In conclusion, nationwide educational programs are necessary to eliminate misconceptions about and negative attitudes toward epilepsy, which still remain present to a considerable extent in Korean society.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132562490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Associated with Hospital Selection by Epilepsy Patients: Medically Intractable versus Pharmacoresponsive Epilepsy 癫痫患者选择医院的相关因素:医学上难治性与药物反应性癫痫
Epilia: Epilepsy and Community Pub Date : 2021-09-30 DOI: 10.35615/epilia.2021.00234
Y. Cho, Keuntae Kim
{"title":"Factors Associated with Hospital Selection by Epilepsy Patients: Medically Intractable versus Pharmacoresponsive Epilepsy","authors":"Y. Cho, Keuntae Kim","doi":"10.35615/epilia.2021.00234","DOIUrl":"https://doi.org/10.35615/epilia.2021.00234","url":null,"abstract":"Background: Hospital selection reflects the decision-making of patients or their caregivers. We in-vestigated the factors related to hospital selection by patients with epilepsy and compared them between patients with medically intractable epilepsy and pharmacoresponsive epilepsy. Methods: This questionnaire-based cross-sectional study evaluated the patients with epilepsy at a university hospital. The patients were asked to complete a series of questions including their demographic information, socio-economic status, and hospital- and patient-related factors related to their selection of a hospital. Results: In total, 230 patients with epilepsy were analyzed, including 66 patients with medically intractable epilepsy and 164 patients with pharmacoresponsive epilepsy. Acquaintances constituted the primary information source that patients with epilepsy used to select a hospital, followed by information from the internet. No patients with pharmacoresponsive epilepsy gathered information from print media. Approximately 94% of patients with medically intractable epilepsy had visited another medical center. As the most important factors for choosing a hospital, the patients gave an av-erage score of at least four out of five for simple administrative procedures (4.03 ± 0.82), the competence of clinicians (4.06 ± 0.89), excellent equipment (4.04 ± 0.85), and reputation of the hospital (4.02 ± 0.88). Conclusions: This is the first study to analyze the factors related to hospital selection among patients with epilepsy in South Korea. This study may contribute to improvements in the medical sys-tem by presenting insights into the medical behavior of patients with epilepsy.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130487718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vagus Nerve Stimulation for Patients with Epilepsy 迷走神经刺激治疗癫痫
Epilia: Epilepsy and Community Pub Date : 2021-09-30 DOI: 10.35615/epilia.2021.00277
S. Nam
{"title":"Vagus Nerve Stimulation for Patients with Epilepsy","authors":"S. Nam","doi":"10.35615/epilia.2021.00277","DOIUrl":"https://doi.org/10.35615/epilia.2021.00277","url":null,"abstract":"approved as an adjunctive therapy for patients with intractable epilepsy in 1999 and has been covered by National Health Insurance in Korea since 2005. VNS is a particularly good option for patients with intractable epilepsy who are not eligible for epilepsy surgery or patients with a high drug load or nonadherence to anticonvulsants. The effect of seizure re-duction by VNS tends to gradually increase in proportion to the duration of treatment. Common side effects are usually mild and transient, including voice change, paresthesia in the neck or throat, and cough. The role of VNS is expected to expand in the future as a substantial proportion of patients show better quality of life with improvements in cognition, language, and behavior, as well as seizure reduction.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131106298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contraception for Women with Epilepsy 女性癫痫患者的避孕措施
Epilia: Epilepsy and Community Pub Date : 2020-09-30 DOI: 10.35615/EPILIA.2020.00164
Jin-Sun Jun
{"title":"Contraception for Women with Epilepsy","authors":"Jin-Sun Jun","doi":"10.35615/EPILIA.2020.00164","DOIUrl":"https://doi.org/10.35615/EPILIA.2020.00164","url":null,"abstract":"뇌전증(epilepsy)은 세계적으로 흔한 신경계 질환으로 여성 1,000명당 약 6.85명의 유병률을 보인다. 가임기 여성 뇌전증 환자들 절반 이상이 계획하지 않은 임신을 한다고 알려져 있는 데, 일부 항경련제가 태아의 주기형 발생을 증가시키고, 조절되 지 않는 경련은 태아에게 위험을 초래할 수 있으므로 안전한 임 신이나 효과적인 피임을 위한 지속적인 관심이 필요하다. 여 성 뇌전증 환자들은 호르몬 피임법과 항경련제가 상호작용을 하 여 각각의 효과를 떨어뜨릴 수 있다는 사실을 인지하지 못하는 경우가 많고 이로 인해 원치 않는 임신을 하거나 경련 조절에 실 패하게 된다. 본 종설에서는 가임기 여성 뇌전증 환자에서 항 경련제와 호르몬 피임법이 서로 어떤 영향을 미치는지 알아보고 여성 뇌전증 환자에서 효과적인 피임법에 대해서 논의해보고자 한다. Epilepsy is a common neurological disease in women worldwide, and more than 50% of women with epilepsy experience unplanned pregnancy. Effective contraception for women with epilepsy of childbearing potential is important, as many antiepileptic drugs interact with hormonal contraception and have the risk of teratogenicity. However, many clinicians and women with epilepsy have insufficient knowledge regarding proper contraception. This article reviews the interactions of antiepileptic drugs with hormonal contraception and offers practical recommendations for contraception management in women with epilepsy.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132684749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Technological Progress and the Human Mind 技术进步与人类思维
Epilia: Epilepsy and Community Pub Date : 2020-03-17 DOI: 10.35615/epilia.2020.00087
J. Ku
{"title":"Technological Progress and the Human Mind","authors":"J. Ku","doi":"10.35615/epilia.2020.00087","DOIUrl":"https://doi.org/10.35615/epilia.2020.00087","url":null,"abstract":"we can hardly conceive of our lives without machines. In particular, as our understanding of the brain—the physical substrate of our minds—deepens, technology is increasingly able to interact directly with the human brain, with profound impacts in many areas. This article will provide an opportunity to reflect on how technical advances interact with our minds and how they will affect our lives in the future.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133679363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Finding the Present with My Son 与我的儿子一起寻找礼物
Epilia: Epilepsy and Community Pub Date : 2019-09-30 DOI: 10.35615/epilia.2019.00045
Su-bin Hwang
{"title":"Finding the Present with My Son","authors":"Su-bin Hwang","doi":"10.35615/epilia.2019.00045","DOIUrl":"https://doi.org/10.35615/epilia.2019.00045","url":null,"abstract":"","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"519 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134239152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Need to more Pay Social Attention and Support to Patients with Epilepsy 社会对癫痫患者需要更多的关注和支持
Epilia: Epilepsy and Community Pub Date : 2019-09-30 DOI: 10.35615/epilia.2019.00002
Ki-Young Jung
{"title":"Need to more Pay Social Attention and Support to Patients with Epilepsy","authors":"Ki-Young Jung","doi":"10.35615/epilia.2019.00002","DOIUrl":"https://doi.org/10.35615/epilia.2019.00002","url":null,"abstract":"뇌전증은 고대메소포타미아 및 이집트 문헌에 기록이 남아있을 만큼 인류의 오래된 질병이다. Epilepsy의 어원은, 고대그리스어인 “epilambanein”에서 유래하였으며, 이는 “신성 혹은 악령에 사로잡 히다”라는 의미로, 고대에서부터 공포나 혐오를 일으키는 대표적인 질환으로 인식되고 있다. 뇌전증에 대한 부정적인 관념은 병태생리가 규명되고 치료제가 개발되고 있는 현 시점에서도 여전 히 남아있어 뇌전증 환자의 삶을 어렵게 하는 요인이 되고 있다. 국내외를 막론하고 뇌전증 환자는 일 반인에 비해 상대적으로 사회관계에서 소외되고, 해고를 당하는 경우가 많고, 결혼이 어려우며, 운전 이나 보험가입에 제약을 받고 있는 것이 현실이다. 이에 뇌전증에 대한 편견과 사회적 차별을 줄이 기 위해서는 뇌전증에 대한 정확한 이해가 선행되어야 하며, 사회의 한 구성원으로서 뇌전증 환우를 포용하는 정책적인 배려가 필요하다. 뇌전증은 경제적 문제보다는 뇌전증으로 받게 될 차별과 사회 로부터 받게 될 부정적인 시선을 우려하여 질병을 드러내는 것을 두려워해 병을 숨기고 치료를 받지 않는 소위 치료간극(treatment gap)이 높은 질환이다. 국내 역학 연구에서 뇌전증 환자는 적어도 20만 명이 될 것으로 추청하고 있으나, 서양보다 높은 사회적 편견과 치료간극을 고려한다면 30여 만 명이 될 것으로 추산하고 있다. 따라서 일반인 뿐만 아니라 환자와 보호자도 사회적 낙인을 타 파하여 자신감을 갖고 당당히 나설 수 있도록 사회적 분위기를 조성하는 것이 필요하다. 뇌전증에 대한 사회적 편견을 줄이고 뇌전증 환자의 삶의 질을 향상시키기 위한 다양한 연구 및 정책을 논할 자리가 필요하나, 기존의 수많은 뇌전증 관련 간행물들은 학술적인 측면이나 임상적인 측면에만 주안점을 두었다. 이에 반해 “에필리아: 뇌전증과 사회”는 대한임상뇌전증연구학회 에필 리아에서 발간하는 공식간행물로서 뇌전증의 최신진단과 치료를 포함한 학술적인 측면 뿐만 아니 라, 사회적·정책적 문제, 뇌전증과 연관된 예술과 역사 등 전인적인 측면으로 접근하고자 하는 것 이 본 간행물의 주 발간목적이다. 에필리아는 뇌전증을 의미하는 epilepsy와 누구나 차별없이 살기 좋은 이상향을 의미하는 utopia의 합성어로서 뇌전증에 대한 편견과 차별을 없애고자 하는 의미이 다. 이러한 소기의 목적을 달성하기 위하여 “에필리아: 뇌전증과 사회”는 임상의사 뿐만 아니라 간 호사, 심리학자, 사회사업가, 정책당국, 언론 및 법조계 등 사회 각계각층의 전문가로부터 소중한 의견과 토론을 담을 것이다. 아울러 환자 및 보호자들의 진솔한 경험과 정책적 바람도 원고로 실릴 것이다. 이에 독자들의 많은 관심과 참여를 바란다. pISSN 2672-0442 eISSN 2672-0450 Epilia: Epilepsy Commun 2019;1(1):2-3 https://doi.org/10.35615/epilia.2019.00002 Editorial","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131031696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Recovery from Complex Regional Pain Syndrome after Super Refractory Status Epilepticus 超级难治性癫痫持续状态后复杂局部疼痛综合征的恢复
Epilia: Epilepsy and Community Pub Date : 2019-09-30 DOI: 10.35615/epilia.2019.00038
Wonshik Kim, Dayoung Kim, Hyemi Lee, D. W. Kim
{"title":"Recovery from Complex Regional Pain Syndrome after Super Refractory Status Epilepticus","authors":"Wonshik Kim, Dayoung Kim, Hyemi Lee, D. W. Kim","doi":"10.35615/epilia.2019.00038","DOIUrl":"https://doi.org/10.35615/epilia.2019.00038","url":null,"abstract":"","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123977663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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