{"title":"Revised Classification and Definition of Epilepsy Syndromes with Onset in Childhood by the International League Against Epilepsy Task Force","authors":"Sunho Lee, J. Yeom","doi":"10.35615/epilia.2023.00403","DOIUrl":"https://doi.org/10.35615/epilia.2023.00403","url":null,"abstract":"","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123163376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Epilepsy Syndrome Classification of International League Against Epilepsy: Idiopathic Generalized Epilepsy Syndromes","authors":"H. Moon","doi":"10.35615/epilia.2023.00396","DOIUrl":"https://doi.org/10.35615/epilia.2023.00396","url":null,"abstract":"","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130398169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The International League Against Epilepsy Classification and Definitions of Epilepsy Syndromes with Onset in Neonates and Infants","authors":"S. Choi","doi":"10.35615/epilia.2023.00389","DOIUrl":"https://doi.org/10.35615/epilia.2023.00389","url":null,"abstract":"","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124632847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Headache in patients with epilepsy: ictal epileptic headache and postictal headache","authors":"Jung-Won Shin","doi":"10.35615/epilia.2023.00375","DOIUrl":"https://doi.org/10.35615/epilia.2023.00375","url":null,"abstract":"","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133422404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The History of Neuroscience 7: Localization of Brain Function after Broca","authors":"Sang Kun Lee","doi":"10.35615/epilia.2023.00382","DOIUrl":"https://doi.org/10.35615/epilia.2023.00382","url":null,"abstract":"","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"277 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114380641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statins in Epilepsy: From Mechanisms to Evidence","authors":"Kyung-il Park","doi":"10.35615/epilia.2022.00354","DOIUrl":"https://doi.org/10.35615/epilia.2022.00354","url":null,"abstract":"While statins were developed as drugs to suppress cholesterol synthesis, they also prevent vascular diseases as off-target effects. Numerous experimental and clinical studies have proven that statins could be beneficial for reducing ictogenesis and epileptogenesis. We aimed to summarize and elabo-rate on up-to-date evidence of the role of statins in epilepsy and consider the mechanisms responsi-ble for their beneficial effects.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132210138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis and Treatment of Depression in Patients with Epilepsy","authors":"Sung-Pa Park","doi":"10.35615/epilia.2022.00347","DOIUrl":"https://doi.org/10.35615/epilia.2022.00347","url":null,"abstract":"Depression has not been highlighted in the field of epilepsy research and treatment despite its harm-ful effects on patients’ daily living. Depression in patients with epilepsy is still underrecognized and undertreated by neurologists due to a lack of training about the psychiatric aspects of neurological disorders, lack of knowledge about the management of depression and the use of antidepressants, lack of time in the outpatient setting, misconceptions about seizure risk with psychotropic medications, and lack of communication with psychiatrists. Therefore, it is critical to acknowledge depression in patients with epilepsy through education and the application of screening tools and establish evidence-based medicine for its treatment. The Neurological Disorders Depression Inventory for Epilepsy is the most efficient and practical screening tool for depression and is also effective to de-tect suicidality in patients with epilepsy. The International League Against Epilepsy recently provided practical recommendations for the treatment of depression in patients with epilepsy. For mild depression, psychotherapy is the first-line treatment, and where medication is used, selective serotonin reuptake inhibitors (SSRIs) are first-choice medications. For moderate to severe depression, SSRIs remain the first-choice medications and psychotherapy can be combined with antidepressants. An-tidepressant treatment should be maintained for at least 6 months following remission from a first depressive episode but it should be prolonged to 9 months in patients with a history of previous epi-sodes and should continue even longer in cases of residual symptomatology until such symptoms have subsided and in those with severe depression.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133668306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Decitabine-Induced Posterior Reversible Encephalopathy Syndrome in a Patient with Myelodysplastic Syndrome","authors":"K. Kang, Y. Kang, Seo-Yeon Ahn, Myeong-Kyu Kim","doi":"10.35615/epilia.2022.00368","DOIUrl":"https://doi.org/10.35615/epilia.2022.00368","url":null,"abstract":"Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterized by its reversibility both radiologically and clinically, and it typically has a favorable prognosis. Its etio-pathogenesis is not clear, although it is known that it involves endothelial dysfunction of the posterior cerebral vasculature, leading to failed cerebral autoregulation. We report a patient with PRES that may have been caused by an immune-mediated response to decitabine.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133473671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eslicarbazepine: Pharmacokinetics and Drug Interactions","authors":"Keuntae Kim, Y. Cho","doi":"10.35615/epilia.2022.00375","DOIUrl":"https://doi.org/10.35615/epilia.2022.00375","url":null,"abstract":"Eslicarbazepine acetate is an advanced antiseizure medication that is an improvement upon carbamazepine and oxcarbazepine. This novel antiseizure medication regulates voltage-gated sodium channels and provides fewer adverse effects and better tolerability. Herein, we present the character-istics, pharmacokinetics, and drug interactions of eslicarbazepine acetate based on the research that has been conducted to date.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128527373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The History of Neuroscience 6: Reflexes and Learning","authors":"S. K. Lee","doi":"10.35615/epilia.2022.00361","DOIUrl":"https://doi.org/10.35615/epilia.2022.00361","url":null,"abstract":"A reflex is an involuntary physiological response evoked by external stimuli. Robert Whytt, though he believed in the spirit, identified the neural pathways that elicit some involuntary actions, including the pupillary light reflex. Bell and Magendie found the ventral and dorsal spinal roots responsible for separate motor and sensory functions. Marshall Hall elucidated the spinal and medullary control of complex reflex behaviors. Charles Sherrington explained in detail the integrative nature of the reflexes, including the importance of both excitation and inhibition. Reflexes became recognized as important factors in the mental process through the contributions of Ivan Sechenov. He highlighted that simple reflexes were the fundamental blocks that create more complex behaviors. Ivan Pavlov discovered the presence of the learned (conditional) reflexes as well as the inborn ones, which had a major impact on the development of psychology. He proposed that all learned behavior was a long chain of conditioned reflexes. Donald Hebb brilliantly described synapses as the key sites in creating learned behavior and memory, which involve large circuits of reflex activities.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124335116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}