{"title":"他汀类药物治疗癫痫:从机制到证据","authors":"Kyung-il Park","doi":"10.35615/epilia.2022.00354","DOIUrl":null,"url":null,"abstract":"While statins were developed as drugs to suppress cholesterol synthesis, they also prevent vascular diseases as off-target effects. Numerous experimental and clinical studies have proven that statins could be beneficial for reducing ictogenesis and epileptogenesis. We aimed to summarize and elabo-rate on up-to-date evidence of the role of statins in epilepsy and consider the mechanisms responsi-ble for their beneficial effects.","PeriodicalId":132321,"journal":{"name":"Epilia: Epilepsy and Community","volume":"31 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Statins in Epilepsy: From Mechanisms to Evidence\",\"authors\":\"Kyung-il Park\",\"doi\":\"10.35615/epilia.2022.00354\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"While statins were developed as drugs to suppress cholesterol synthesis, they also prevent vascular diseases as off-target effects. Numerous experimental and clinical studies have proven that statins could be beneficial for reducing ictogenesis and epileptogenesis. We aimed to summarize and elabo-rate on up-to-date evidence of the role of statins in epilepsy and consider the mechanisms responsi-ble for their beneficial effects.\",\"PeriodicalId\":132321,\"journal\":{\"name\":\"Epilia: Epilepsy and Community\",\"volume\":\"31 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Epilia: Epilepsy and Community\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35615/epilia.2022.00354\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Epilia: Epilepsy and Community","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35615/epilia.2022.00354","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
While statins were developed as drugs to suppress cholesterol synthesis, they also prevent vascular diseases as off-target effects. Numerous experimental and clinical studies have proven that statins could be beneficial for reducing ictogenesis and epileptogenesis. We aimed to summarize and elabo-rate on up-to-date evidence of the role of statins in epilepsy and consider the mechanisms responsi-ble for their beneficial effects.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
