HpbPub Date : 2026-04-01Epub Date: 2025-12-01DOI: 10.1016/j.hpb.2025.12.002
Najeeb Aftab
{"title":"Artificial intelligence and the real question behind MRCP selection","authors":"Najeeb Aftab","doi":"10.1016/j.hpb.2025.12.002","DOIUrl":"10.1016/j.hpb.2025.12.002","url":null,"abstract":"","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"28 4","pages":"Page 595"},"PeriodicalIF":2.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145756437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HpbPub Date : 2026-04-01Epub Date: 2025-12-17DOI: 10.1016/j.hpb.2025.12.025
Carlos Manterola , Josue Rivadeneira , Luis Alvarado , Luis Grande
{"title":"Evaluation of Charlson comorbidity index as a predictor of postoperative complications in patients with hepatic cystic echinococcosis. A nested case-control study","authors":"Carlos Manterola , Josue Rivadeneira , Luis Alvarado , Luis Grande","doi":"10.1016/j.hpb.2025.12.025","DOIUrl":"10.1016/j.hpb.2025.12.025","url":null,"abstract":"<div><h3>Background</h3><div>Postoperative complications (POC) in surgery for hepatic cystic echinococcosis (HCE) still being frequent. Comorbidities as a risk factor has not yet been studied. The aim of this study was to evaluate the predictive value of CCI for POC in surgically treated HCE patients.</div></div><div><h3>Methods</h3><div>Nested case–control study. Patients undergoing elective surgery for HCE between 2011 and 2019; matched (1:1) by sex, cyst diameter and time follow-up were included. Cases were patients with CCI≥3; and controls, patients with CCI≤2. Primary outcome was POC. Descriptive statistics and bivariate analyses were applied. Logistic regression was used, odds ratios (OR) and their respective 95 % confidence intervals (CI95 %), were calculated.</div></div><div><h3>Results</h3><div>226 patients (113 cases and 113 controls) were analyzed. Significant differences were verified between cases and controls in frequency of evolutionary complications of HCE (OR: 5.5; <em>p</em> = 0.0003); and major rate of ASA I-II in controls (OR: 0.07; <em>p</em> < 0.0001). A great rate of POC (OR: 3.58; <em>p</em> = 0.0002); and Clavien ≥ IIIb POC more frequent in cases were found (OR: 7.00; <em>p</em> = 0.031). Applying logistic regression model, CCI score≥3 was identified as an independent prognostic factor for POC (OR: 6.29 [CI95 %: 2.1–18.8; <em>p</em> < 0.01]).</div></div><div><h3>Conclusion</h3><div>In this study, cases showed higher frequency and severity of POC than controls.</div></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"28 4","pages":"Pages 508-514"},"PeriodicalIF":2.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HpbPub Date : 2026-03-26DOI: 10.1016/j.hpb.2026.03.006
Mei-Ling Zhou, Yong-Gang Huang
{"title":"Optimal timing and surgical expertise in early cholecystectomy for mild biliary pancreatitis.","authors":"Mei-Ling Zhou, Yong-Gang Huang","doi":"10.1016/j.hpb.2026.03.006","DOIUrl":"https://doi.org/10.1016/j.hpb.2026.03.006","url":null,"abstract":"","PeriodicalId":13229,"journal":{"name":"Hpb","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HpbPub Date : 2026-03-24DOI: 10.1016/j.hpb.2026.03.005
Kjetil Søreide, Kim Waardal, Dyre Kleive
{"title":"Pancreatoduodenectomy with vascular resection in a population-derived cohort: time-trends, effect on short-term composite outcome and relevance for overall survival.","authors":"Kjetil Søreide, Kim Waardal, Dyre Kleive","doi":"10.1016/j.hpb.2026.03.005","DOIUrl":"https://doi.org/10.1016/j.hpb.2026.03.005","url":null,"abstract":"<p><strong>Background: </strong>Pancreatoduodenectomy with vascular resections increase complexity and potentially also morbidity and mortality. Data outside single-institution cohorts are limited. Thus, we analysed population-derived trends in pancreatoduodenectomy with vascular resection.</p><p><strong>Methods: </strong>A registry-based, population-derived cohort (years 2018-2023) of pancreatoduodenectomy ± vascular resection in a universal health care system analysed for effect on short-term composite textbook outcome and overall survival.</p><p><strong>Results: </strong>Of 860 pancreatoduodenectomies, 138 (16%) had concomitant vascular resection (vein resections, n = 120; 87%); n = 14 (10%) artery; n = 4 (3%) combined artery + vein). Vascular resection-rate increased (13.8%-18.3%) over time and most were done for malignancy (n = 113, 82%). Inhospital mortality (2.2% vs. 1.9%) did not differ when adding vascular resection. Composite textbook rates were comparable for pancreatoduodenectomy ± vascular resection (n = 75, 54.3% and n = 430, 59.6%, P = 0.255). Pancreatoduodenectomy with vascular resection had a higher rate of reoperation (16.7% compared to 10.0%; OR 1.81, 95% c.i. 1.09-3.01; P = 0.022), which also differed between regions. Overall long-term survival was significantly shorter if vascular resection was performed without neoadjuvant treatment; no difference was observed after neoadjuvant treatment for pancreatoduodenectomy ± vascular resection.</p><p><strong>Conclusion: </strong>The population-derived vascular resection rates increased over time with no noted negative effects on overall complication rate nor for achieved textbook outcome, but a significantly higher risk for reoperations.</p>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HpbPub Date : 2026-03-24DOI: 10.1016/j.hpb.2026.03.004
Ibelema Datubo-Brown, Prudence U Ikejiofor, Ibrahim U Garzali, Lahja Negumbo, Vihar Kotecha, Olusegun I Alatise
{"title":"Hepato-pancreato-biliary surgery in sub-saharan Africa: challenges and charting the way forward.","authors":"Ibelema Datubo-Brown, Prudence U Ikejiofor, Ibrahim U Garzali, Lahja Negumbo, Vihar Kotecha, Olusegun I Alatise","doi":"10.1016/j.hpb.2026.03.004","DOIUrl":"https://doi.org/10.1016/j.hpb.2026.03.004","url":null,"abstract":"<p><strong>Background: </strong>Hepato-pancreato-biliary (HPB) surgery is highly specialized, requiring advanced training and infrastructure. Despite significant disease burden, sub-Saharan Africa has limited HPB capacity. This survey evaluated current HPB surgical practice across the region.</p><p><strong>Methods: </strong>A cross-sectional survey targeting surgeons in sub-Saharan Africa assessed training background, institutional infrastructure, surgical capabilities, equipment availability, and surgical volume.</p><p><strong>Results: </strong>Fifty-seven valid responses from 43 institutions across 11 countries were analyzed. Most respondents (71.9%) were based in tertiary hospitals. Only 24.6% received HPB training; ERCP training was 12.3%. Training prevalence increased significantly with surgical experience (≤5 years: 14.3% vs > 10 years: 60.0%, p = 0.012). CT scanning was available in 80.7%, but advanced imaging was scarce (EUS 8.8%, PET 7.0%). Laparoscopic capability was reported by 66.7%, though open surgery predominated (77.2% for biliary procedures). Nearly half (48.2%) lacked suitable retraction systems. Access to advanced energy devices was significantly associated with training status (71.4% trained vs 27.9% untrained, p = 0.010).</p><p><strong>Conclusion: </strong>HPB surgical capacity in sub-Saharan Africa shows critical deficits in training, infrastructure, and equipment, with regional heterogeneity. Associations between experience, training, and equipment reveal concentration patterns demanding coordinated capacity-building.</p>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147722953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HpbPub Date : 2026-03-19DOI: 10.1016/j.hpb.2026.03.003
Karl J Oldhafer, Kim C Wagner, Mohammad Fard-Aghaie, Jörg Böcker, Naruhiko Honmyo
{"title":"Parenchyma-preserving hepatectomy in pCCA: additional evidence supporting central hepatectomy.","authors":"Karl J Oldhafer, Kim C Wagner, Mohammad Fard-Aghaie, Jörg Böcker, Naruhiko Honmyo","doi":"10.1016/j.hpb.2026.03.003","DOIUrl":"https://doi.org/10.1016/j.hpb.2026.03.003","url":null,"abstract":"","PeriodicalId":13229,"journal":{"name":"Hpb","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147615965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HpbPub Date : 2026-03-14DOI: 10.1016/j.hpb.2026.03.001
Lina Aguilera Munoz, Lucie Laurent, Sandra Salmeron, Diane Lorenzo, Alain Sauvanet, François Paye, Magali Svrcek, Julie Navez, Claire Michoud, Jean-Christophe Saurin, Julie Périnel, Mustapha Adham, Julien Branche, Lilian Schwarz, Thomas Chaigneau, Benoit Dupont, Ecoline Tribillon, Charles de Ponthaud, Sébastien Gaujoux, Bertrand Napoléon, Christelle d'Engremont, Teddy Deregnaucourt, Fanny Foubert, Marc Le Rhun, Maxime Ronot, Rémy Nicolle, Olivier Ernst, Jérôme Cros, Marie-Pierre Vullierme, Vinciane Rebours
{"title":"Risk prediction model for high-grade dysplasia in resected pancreatic mucinous cystic neoplasms: a nomogram-based approach.","authors":"Lina Aguilera Munoz, Lucie Laurent, Sandra Salmeron, Diane Lorenzo, Alain Sauvanet, François Paye, Magali Svrcek, Julie Navez, Claire Michoud, Jean-Christophe Saurin, Julie Périnel, Mustapha Adham, Julien Branche, Lilian Schwarz, Thomas Chaigneau, Benoit Dupont, Ecoline Tribillon, Charles de Ponthaud, Sébastien Gaujoux, Bertrand Napoléon, Christelle d'Engremont, Teddy Deregnaucourt, Fanny Foubert, Marc Le Rhun, Maxime Ronot, Rémy Nicolle, Olivier Ernst, Jérôme Cros, Marie-Pierre Vullierme, Vinciane Rebours","doi":"10.1016/j.hpb.2026.03.001","DOIUrl":"https://doi.org/10.1016/j.hpb.2026.03.001","url":null,"abstract":"<p><strong>Background: </strong>Mucinous cystic neoplasms (MCN) are precancerous pancreatic lesions. Their management is challenged by the lack of robust predictors of malignancy. This study aimed to identify preoperative predictors of high-grade dysplasia (HGD) or invasive carcinoma and to develop a predictive nomogram.</p><p><strong>Methods: </strong>This multicenter retrospective study included patients who underwent resection for MCN between 2008 and 2021 across 13 centers. Surgical decisions were based on European guideline criteria. Diagnosis required ovarian-type stroma. Preoperative CT/MRI were centrally reviewed by an expert radiologist blinded to pathology. Independent predictors of ≥HGD were identified using multivariable logistic regression.</p><p><strong>Results: </strong>Among 198 patients, 32 (16 %) had ≥ HGD, including 14 (7 %) with invasive carcinoma. Independent predictors were older age (median 52.5 vs 45 years, p = 0.01), symptomatic presentation (72% vs 47%, OR 2.88, p = 0.01), larger cyst size (85 vs 46.5 mm, p < 0.001), and mural nodules (56% vs 15 %, OR 7.25, p < 0.001). The nomogram achieved an accuracy of 0.89 and an AUC of 0.86; a 10% risk threshold provided 85 % sensitivity. An interactive web-based calculator is publicly available.</p><p><strong>Conclusion: </strong>Age, symptoms, cyst size, and mural nodules independently predict malignancy in resected MCNs. A validated nomogram and online calculator may support individualized surgical versus surveillance strategies.</p>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147573722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HpbPub Date : 2026-03-12DOI: 10.1016/j.hpb.2026.03.002
Preeti Lamba
{"title":"Reconsidering the optimal timing of cholecystectomy in mild acute biliary pancreatitis: implications for surgical decision-making.","authors":"Preeti Lamba","doi":"10.1016/j.hpb.2026.03.002","DOIUrl":"https://doi.org/10.1016/j.hpb.2026.03.002","url":null,"abstract":"","PeriodicalId":13229,"journal":{"name":"Hpb","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147520683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}