IEEE Transactions on Biomedical Circuits and Systems最新文献_第7页

Proceedings of the 2013 IEEE Biomedical Circuits and Systems Conference (BioCAS 2013) on Advancing Healthcare Technology, October 31-November 2, 2013, Rotterdam, Netherlands. 2013年IEEE生物医学电路与系统会议论文集(BioCAS 2013):推进医疗技术，2013年10月31日至11月2日，荷兰鹿特丹。

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2014-10-01

引用次数: 0

18.7 A remotely controlled locomotive IC driven by electrolytic bubbles and wireless powering 18.7一种电解气泡驱动、无线供电的遥控机车集成电路

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2014-03-06 DOI: 10.1109/ISSCC.2014.6757453

Po-Hung Kuo, J. Hsieh, Yi-Chun Huang, Yu-Jie Huang, Rong-Da Tsai, Tao Wang, Hung-Wei Chiu, Shey-Shi Lu

{"title":"18.7 A remotely controlled locomotive IC driven by electrolytic bubbles and wireless powering","authors":"Po-Hung Kuo, J. Hsieh, Yi-Chun Huang, Yu-Jie Huang, Rong-Da Tsai, Tao Wang, Hung-Wei Chiu, Shey-Shi Lu","doi":"10.1109/ISSCC.2014.6757453","DOIUrl":"https://doi.org/10.1109/ISSCC.2014.6757453","url":null,"abstract":"As implantable medical CMOS devices become a reality [1], motion control of such implantable devices has become the next challenge in the advanced integrated micro-system domain. With integrated sensors and a controllable propulsion mechanism, a micro-system will be able to perform tumor scan, drug delivery, neuron stimulation, bio-test, etc, in a revolutionary way and with minimum injury. Such devices are especially suitable for human hollow organs, such as urinary bladder and stomach. Motivated by the art reported in ISSCC 2012 [2], we demonstrate a remotely-controlled locomotive CMOS IC which is realized in TSMC 0.35μm technology. As illustrated in Fig. 18.7.1, a bare CMOS chip flipped on a liquid surface can be moved to the desired position without any wire connections. Instead of Lorentz forces [2], this chip utilizes the gas pressure resulting from electrolytic bubbles as the propulsive force. By appointing voltages to the on-chip electrolysis electrodes, one can decide the electrolysis location and thereby control the bubbles emissions as well as the direction of motion. With power management circuits, wireless receiver and micro-control unit (MCU), the received signal can be exploited as the movement control as well as wireless power. Experiments show a moving speed of 0.3mm/s of this chip. The total size is 21.2mm2 and the power consumption of the integrated circuits and the electrolysis electrodes are 125.4μW and 82μW, respectively.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"1 1","pages":"322-323"},"PeriodicalIF":5.1,"publicationDate":"2014-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ISSCC.2014.6757453","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62165926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

An Energy-Efficient, Dynamic Voltage Scaling Neural Stimulator for a Proprioceptive Prosthesis 一种用于本体感觉假体的节能、动态电压缩放神经刺激器

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2012-05-20 DOI: 10.1109/ISCAS.2012.6271420

I. Williams, T. Constandinou

{"title":"An Energy-Efficient, Dynamic Voltage Scaling Neural Stimulator for a Proprioceptive Prosthesis","authors":"I. Williams, T. Constandinou","doi":"10.1109/ISCAS.2012.6271420","DOIUrl":"https://doi.org/10.1109/ISCAS.2012.6271420","url":null,"abstract":"This paper presents an 8 channel energy-efficient neural stimulator for generating charge-balanced asymmetric pulses. Power consumption is reduced by implementing a fully-integrated DC-DC converter that uses a reconfigurable switched capacitor topology to provide 4 output voltages for Dynamic Voltage Scaling (DVS). DC conversion efficiencies of up to 82% are achieved using integrated capacitances of under 1 nF and the DVS approach offers power savings of up to 50% compared to the front end of a typical current controlled neural stimulator. A novel charge balancing method is implemented which has a low level of accuracy on a single pulse and a much higher accuracy over a series of pulses. The method used is robust to process and component variation and does not require any initial or ongoing calibration. Measured results indicate that the charge imbalance is typically between 0.05%-0.15% of charge injected for a series of pulses. Ex-vivo experiments demonstrate the viability in using this circuit for neural activation. The circuit has been implemented in a commercially-available 0.18 μm HV CMOS technology and occupies a core die area of approximately 2.8 mm2 for an 8 channel implementation.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"7 1","pages":"129-139"},"PeriodicalIF":5.1,"publicationDate":"2012-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ISCAS.2012.6271420","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62145716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 95

Proceedings of the 2011 IEEE International Symposium on Circuits and Systems (ISCAS 2011), May 15-18, 2011, Rio de Janeiro, Brazil. 2011年IEEE电路与系统国际研讨会论文集，2011年5月15-18日，巴西里约热内卢。

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2012-04-01

引用次数: 0

Dielectrophoresis-Based Integrated Lab-on-Chip for Nano and Micro-Particles Manipulation and Capacitive Detection 基于介电泳的纳米和微粒子操作和电容检测集成芯片实验室

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2012-03-02 DOI: 10.1109/TBCAS.2013.2271727

M. A. Miled, G. Massicotte, M. Sawan

{"title":"Dielectrophoresis-Based Integrated Lab-on-Chip for Nano and Micro-Particles Manipulation and Capacitive Detection","authors":"M. A. Miled, G. Massicotte, M. Sawan","doi":"10.1109/TBCAS.2013.2271727","DOIUrl":"https://doi.org/10.1109/TBCAS.2013.2271727","url":null,"abstract":"We present in this paper a new Lab-on-Chip (LoC) architecture for dielectrophoresis-based cell manipulation, detection, and capacitive measurement. The proposed LoC is built around a CMOS full-custom chip and a microfluidic structure. The CMOS chip is used to deliver all parameters required to control the dielectrophoresis (DEP) features such as frequency, phase, and amplitude of signals spread on in-channel electrodes of the LoC. It is integrated to the LoC and experimental results are related to micro and nano particles manipulation and detection in a microfluidic platform. The proposed microsystem includes an on-chip 27-bit frequency divider, a digital phase controller with a 3.6° phase shift resolution and a 2.5 V dynamic range. The sensing module is composed of a 3 × 3 capacitive sensor array with 10 fF per mV sensitivity, and a dynamic range of 1.5 V. The obtained results show an efficient nano and micro-particles (PC05N, PA04N and PS03N) separation based on frequency segregation with low voltages less than 1.7 V and a fully integrated and reconfigurable system.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"6 1","pages":"120-132"},"PeriodicalIF":5.1,"publicationDate":"2012-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2013.2271727","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62964615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 59

CMOS Low Current Measurement System for Biomedical Applications 生物医学应用CMOS低电流测量系统

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2011-05-15 DOI: 10.1109/ISCAS.2011.5937741

Brian Goldstein, Dongsoo Kim, A. Rottigni, Jian Xu, T. Vanderlick, E. Culurciello

引用次数: 64

A VLSI Neural Monitoring System With Ultra-Wideband Telemetry for Awake Behaving Subjects 基于超宽带遥测技术的清醒行为对象VLSI神经监测系统

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2010-08-03 DOI: 10.1109/ISCAS.2010.5537299

Elliot Greenwald, M. Mollazadeh, N. Thakor, Wei Tang, E. Culurciello

{"title":"A VLSI Neural Monitoring System With Ultra-Wideband Telemetry for Awake Behaving Subjects","authors":"Elliot Greenwald, M. Mollazadeh, N. Thakor, Wei Tang, E. Culurciello","doi":"10.1109/ISCAS.2010.5537299","DOIUrl":"https://doi.org/10.1109/ISCAS.2010.5537299","url":null,"abstract":"Long-term monitoring of neuronal activity in awake behaving subjects can provide fundamental information about brain dynamics for neuroscience and neuroengineering applications. Here, we present a miniature, lightweight, and low-power recording system for monitoring neural activity in awake behaving animals. The system integrates two custom designed very-large-scale integrated chips, a neural interface module fabricated in 0.5 μm complementary metal-oxide semiconductor technology and an ultra-wideband transmitter module fabricated in a 0.5 μm silicon-on-sapphire (SOS) technology. The system amplifies, filters, digitizes, and transmits 16 channels of neural data at a rate of 1 Mb/s. The entire system, which includes the VLSI circuits, a digital interface board, a battery, and a custom housing, is small and lightweight (24 g) and, thus, can be chronically mounted on small animals. The system consumes 4.8 mA and records continuously for up to 40 h powered by a 3.7-V, 200-mAh rechargeable lithium-ion battery. Experimental benchtop characterizations as well as in vivo multichannel neural recordings from awake behaving rats are presented here.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"1 1","pages":"112-119"},"PeriodicalIF":5.1,"publicationDate":"2010-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ISCAS.2010.5537299","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62145620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 41

Neural dynamics in reconfigurable silicon 可重构硅中的神经动力学

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2010-05-01 DOI: 10.1109/ISCAS.2010.5536960

Arindam Basu, Shubha Ramakrishnan, P. Hasler

引用次数: 0

Pain control on demand based on pulsed radio-frequency stimulation of the dorsal root ganglion using a batteryless implantable CMOS SoC 基于脉冲射频刺激背根神经节的疼痛控制需求，使用无电池植入式CMOS SoC

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2010-03-18 DOI: 10.1109/ISSCC.2010.5433936

Chii-Wann Lin, Hung-Wei Chiu, M. Lin, Chi-Heng Chang, I-Hsiu Ho, Po Hsiang Fang, Yi Chin Li, Chang Lun Wang, Yao-Chuan Tsai, Y. Wen, Win-Pin Shih, Y. Yang, Shey-Shi Lu

{"title":"Pain control on demand based on pulsed radio-frequency stimulation of the dorsal root ganglion using a batteryless implantable CMOS SoC","authors":"Chii-Wann Lin, Hung-Wei Chiu, M. Lin, Chi-Heng Chang, I-Hsiu Ho, Po Hsiang Fang, Yi Chin Li, Chang Lun Wang, Yao-Chuan Tsai, Y. Wen, Win-Pin Shih, Y. Yang, Shey-Shi Lu","doi":"10.1109/ISSCC.2010.5433936","DOIUrl":"https://doi.org/10.1109/ISSCC.2010.5433936","url":null,"abstract":"Although pain is interpreted as the fifth vital sign by many professions, the presence of different degrees of pain significantly affects quality of life for many patients, especially the elderly [1]. Electrical stimulation to the central or peripheral neural conduction paths has been utilized in clinics to achieve effective pain relief [2]. The conventional scheme for pulsed radio-frequency (PRF) pain therapy uses thermal coagulation to permanently damage nerves by heat. This destructive method can cause severe side-effects such as hyper-sensitivity to pain after nerves regenerate. Thus, repeated surgery is needed. Additionally, the conventional design of an implantable system requires a battery for operation, often accounting for over 2/3 of the entire device volume. Therefore, a non-destructive and batteryless method using PRF for pain control is key for implantable systems. This work uses a batteryless implantable pain-control SoC that is effective in pain reduction, using a low stimulation voltage that avoids causing thermal damage to dorsal root ganglion (DRG) tissue. An animal study of neuropathic pain was previously designed with PRF parameters to control tissue temperature at ≪40°C via an external function generator [3]. This work now presents the implementation of this functionality on a CMOS SoC. Its effectiveness is demonstrated by observing the behavior of rats receiving localized bipolar stimulus to the DRG of the lumbar nerve.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"1 1","pages":"234-235"},"PeriodicalIF":5.1,"publicationDate":"2010-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ISSCC.2010.5433936","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62165546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

A Wireless IC for Wide-Range Neurochemical Monitoring Using Amperometry and Fast-Scan Cyclic Voltammetry 应用安培法和快速扫描循环伏安法进行大范围神经化学监测的无线集成电路

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2007-05-27 DOI: 10.1109/ISCAS.2007.378094

M. Roham, P. Mohseni

{"title":"A Wireless IC for Wide-Range Neurochemical Monitoring Using Amperometry and Fast-Scan Cyclic Voltammetry","authors":"M. Roham, P. Mohseni","doi":"10.1109/ISCAS.2007.378094","DOIUrl":"https://doi.org/10.1109/ISCAS.2007.378094","url":null,"abstract":"An integrated circuit for real-time wireless monitoring of neurochemical activity in the nervous system is described. The chip is capable of conducting measurements in both fast-scan cyclic voltammetry (FSCV) and amperometry modes for a wide input current range. The chip architecture employs a second-order DeltaSigma modulator (DeltaSigmaM) and a frequency-shift-keyed transmitter operating near 433 MHz. It is fabricated using the AMI 0.5-mum double-poly triple-metal n-well CMOS process, and requires only one off-chip component for operation. A measured current resolution of 12 pA at a sampling rate of 100 Hz and 132 pA at a sampling rate of 10 kHz is achieved in amperometry and 300-V/s FSCV modes, respectively, for any input current in the range of plusmn430 nA. The modulator core and the transmitter draw 22 and 400 muA from a 2.6-V power supply, respectively. The chip has been externally interfaced with a carbon-fiber microelectrode implanted acutely in the caudate-putamen of an anesthetized rat, and, for the first time, extracellular levels of dopamine elicited by electrical stimulation of the medial forebrain bundle have been successfully recorded wirelessly using 300-V/s FSCV.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"2 1","pages":"3-9"},"PeriodicalIF":5.1,"publicationDate":"2007-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/ISCAS.2007.378094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62144839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13