IEEE Transactions on Biomedical Circuits and Systems最新文献

{"title":"A 1024-Channel Simultaneous Electrophysiological and Electrochemical Neural Recording System with In-Pixel Digitization and Crosstalk Compensation","authors":"Xinguo Wang, Songyu Han, Peng Yan, Yang Lin, Chen Wang, Lei Qian, Pujia Xing, Yue Cao, Xinglei Song, Guoxing Wang, Timothy G. Constandinou, Yan Liu","doi":"10.1109/tbcas.2024.3460388","DOIUrl":"https://doi.org/10.1109/tbcas.2024.3460388","url":null,"abstract":"","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"100 1","pages":""},"PeriodicalIF":5.1,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 13.56-MHz 93.5%-Efficiency Optimal On/Off Timing Tracking Active Rectifier with Digital Feedback-Based Adaptive Delay Control","authors":"Jisan Ahn, Hyun-Su Lee, Kyeongho Eom, Woojoong Jung, Hyung-Min Lee","doi":"10.1109/tbcas.2024.3457848","DOIUrl":"https://doi.org/10.1109/tbcas.2024.3457848","url":null,"abstract":"","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"105 1","pages":""},"PeriodicalIF":5.1,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Ultra-Low Power Wearable BMI System with Continual Learning Capabilities","authors":"Lan Mei, Thorir Mar Ingolfsson, Cristian Cioflan, Victor Kartsch, Andrea Cossettini, Xiaying Wang, Luca Benini","doi":"10.1109/tbcas.2024.3457522","DOIUrl":"https://doi.org/10.1109/tbcas.2024.3457522","url":null,"abstract":"","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"1 1","pages":""},"PeriodicalIF":5.1,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142195023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Portable Cardiac Dynamic Monitoring System in the Framework of Electro-Mechano-Acoustic Mapping.","authors":"Zhixing Gao, Yuqi Wang, Xingchen Xu, Chaohong Zhang, Zhiwei Dai, Haiying Zhang, Jun Zhang, Hao Yang","doi":"10.1109/TBCAS.2023.3307188","DOIUrl":"10.1109/TBCAS.2023.3307188","url":null,"abstract":"<p><p>Abnormalities in cardiac function arise irregularly and typically involve multimodal electrical, mechanical vibrations, and acoustics alterations. This paper proposes an Electro-Mechano-Acoustic (EMA) activity model for mapping the complete macroscopic cardiac function to refine the systematic interpretation of cardiac multimodal assessment. We abstract this activity pattern and build the mapping system by analyzing the functional comparison of the heart pump and Electronic Fuel Injection (EFI) system from the multimodal characteristics of the heart. Electrocardiogram (ECG), seismocardiogram (SCG) & Ultra-Low Frequency seismocardiogram (ULF-SCG), and Phonocardiogram (PCG) are selected to implement the EMA mapping respectively. First, a novel low-frequency cardiograph compound sensor capable of extracting both SCG and ULF-SCG is proposed, which is integrated with ECG and PCG modules on a single hardware device for portable dynamic acquisition. Afterward, a multimodal signal processing chain further analyses the acquired synchronized signals, and the extracted ULF-SCG is shown to indicate changes in heart volume. In particular, the proposed method based on waveform curvature is used to extract 9 feature points of the SCG signal, and the overall recognition accuracy reaches over 90% in the data collected by EMA portable device. Ultimately, we integrate the portable device and signal processing chains to form the EMA cardiovascular mapping system (EMACMS). As a next-generation system solution for cardiac daily dynamic monitoring, which can map the mechanical coupling and electromechanical coupling process, extract multi-characteristic heart rate variability (HRV), and enable extraction of important time intervals of cardiac activity to assess cardiac function.</p>","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"PP ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10081420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy-Efficient Intelligent ECG Monitoring for Wearable Devices","authors":"Ni Wang, Jun Zhou, Guanghai Dai, Jiahui Huang, Yuxiang Xie","doi":"10.1109/TBCAS.2019.2930215","DOIUrl":"https://doi.org/10.1109/TBCAS.2019.2930215","url":null,"abstract":"Wearable intelligent ECG monitoring devices can perform automatic ECG diagnosis in real time and send out alert signal together with abnormal ECG signal for doctor's further analysis. This provides a means for the patient to identify their heart problem as early as possible and go to doctors for medical treatment. For such system the key requirements include high accuracy and low power consumption. However, the existing wearable intelligent ECG monitoring schemes suffer from high power consumption in both ECG diagnosis and transmission in order to achieve high accuracy. In this work, we have proposed an energy-efficient wearable intelligent ECG monitor scheme with two-stage end-to-end neural network and diagnosis-based adaptive compression. Compared to the state-of-the-art schemes, it significantly reduces the power consumption in ECG diagnosis and transmission while maintaining high accuracy.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"13 1","pages":"1112-1121"},"PeriodicalIF":5.1,"publicationDate":"2019-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2019.2930215","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62967101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of a Closed-Loop, Bidirectional Brain Machine Interface System With Energy Efficient Neural Feature Extraction and PID Control","authors":"Xilin Liu, Milin Zhang, A. Richardson, T. Lucas, J. van der Spiegel","doi":"10.1109/TBCAS.2016.2622738","DOIUrl":"https://doi.org/10.1109/TBCAS.2016.2622738","url":null,"abstract":"This paper presents a bidirectional brain machine interface (BMI) microsystem designed for closed-loop neuroscience research, especially experiments in freely behaving animals. The system-on-chip (SoC) consists of 16-channel neural recording front-ends, neural feature extraction units, 16-channel programmable neural stimulator back-ends, in-channel programmable closed-loop controllers, global analog-digital converters (ADC), and peripheral circuits. The proposed neural feature extraction units includes 1) an ultra low-power neural energy extraction unit enabling a 64-step natural logarithmic domain frequency tuning, and 2) a current-mode action potential (AP) detection unit with time-amplitude window discriminator. A programmable proportional-integral-derivative (PID) controller has been integrated in each channel enabling a various of closed-loop operations. The implemented ADCs include a 10-bit voltage-mode successive approximation register (SAR) ADC for the digitization of the neural feature outputs and/or local field potential (LFP) outputs, and an 8-bit current-mode SAR ADC for the digitization of the action potential outputs. The multi-mode stimulator can be programmed to perform monopolar or bipolar, symmetrical or asymmetrical charge balanced stimulation with a maximum current of 4 mA in an arbitrary channel configuration. The chip has been fabricated in 0.18<inline-formula><tex-math notation=\"LaTeX\">$mu$</tex-math></inline-formula> m CMOS technology, occupying a silicon area of 3.7 mm<inline-formula><tex-math notation=\"LaTeX\">$^2$</tex-math></inline-formula>. The chip dissipates 56 <inline-formula><tex-math notation=\"LaTeX\">$mu$</tex-math></inline-formula>W/ch on average. General purpose low-power microcontroller with Bluetooth module are integrated in the system to provide wireless link and SoC configuration. Methods, circuit techniques and system topology proposed in this work can be used in a wide range of relevant neurophysiology research, especially closed-loop BMI experiments.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"11 1","pages":"729-742"},"PeriodicalIF":5.1,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2016.2622738","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62966491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parallel distribution of an inner hair cell and auditory nerve model for real-time application","authors":"R. James, J. Garside, Michael Hopkins, L. Plana, S. Temple, Simon Davidson, S. Furber","doi":"10.1109/BIOCAS.2017.8325171","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325171","url":null,"abstract":"This paper summarises recent efforts into implementing a model of the inner hair cell and auditory nerve on a neuromorphic hardware platform, the SpiNNaker machine. Such an implementation exploits the massive parallelism of the target architecture to obtain real-time modelling to a biologically realistic number of human auditory nerve fibres. The potential for incorporating this implementation into a full-scale digital realtime model of the human auditory pathway is then discussed.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"1 1","pages":"1-4"},"PeriodicalIF":5.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/BIOCAS.2017.8325171","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62152843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Flexible, Micro-Lens-Coupled LED Stimulator for Optical Neuromodulation.","authors":"Xiao-Peng Bi, Tian Xie, B. Fan, W. Khan, Yue Guo, Wen Li","doi":"10.1109/TBCAS.2016.2599406","DOIUrl":"https://doi.org/10.1109/TBCAS.2016.2599406","url":null,"abstract":"Optogenetics is a fast growing neuromodulation method, which can remotely manipulate the specific activities of genetically-targeted neural cells and associated biological behaviors with millisecond temporal precision through light illumination. Application of optogenetics in neuroscience studies has created an increased need for the development of light sources and the instruments for light delivery. This paper presents a micro-lens-coupled LED neural stimulator which includes a backside reflector and a frontside microlens for light collection and collimation. The device structure has been optimized using optical simulation and the optimized device is able to increase the volume of excitable tissues by 70.4%. Device prototypes have been fabricated and integrated based on an optimization of the device structure. The measurement results show that the light power increases by 99% at an effective penetration depth of 5 000 [Formula: see text] by the fabricated device under various voltages of 2.4-3.2 V.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"10 5 1","pages":"972-978"},"PeriodicalIF":5.1,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2016.2599406","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62966258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Bidirectional Neural Interface IC With Chopper Stabilized BioADC Array and Charge Balanced Stimulator","authors":"Elliot Greenwald, Ernest So, Qihong Wang, M. Mollazadeh, C. Maier, R. Etienne-Cummings, G. Cauwenberghs, N. Thakor","doi":"10.1109/TBCAS.2016.2614845","DOIUrl":"https://doi.org/10.1109/TBCAS.2016.2614845","url":null,"abstract":"We present a bidirectional neural interface with a 4-channel biopotential analog-to-digital converter (bioADC) and a 4-channel current-mode stimulator in 180 nm CMOS. The bioADC directly transduces microvolt biopotentials into a digital representation without a voltage-amplification stage. Each bioADC channel comprises a continuous-time first-order ΔΣ modulator with a chopper-stabilized OTA input and current feedback, followed by a second-order comb-filter decimator with programmable oversampling ratio. Each stimulator channel contains two independent digital-to-analog converters for anodic and cathodic current generation. A shared calibration circuit matches the amplitude of the anodic and cathodic currents for charge balancing. Powered from a 1.5 V supply, the analog and digital circuits in each recording channel draw on average 1.54 μA and 2.13 μA of supply current, respectively. The bioADCs achieve an SNR of 58 dB and a SFDR of >70 dB, for better than 9-b ENOB. Intracranial EEG recordings from an anesthetized rat are shown and compared to simultaneous recordings from a commercial reference system to validate performance in-vivo. Additionally, we demonstrate bidirectional operation by recording cardiac modulation induced through vagus nerve stimulation, and closed-loop control of cardiac rhythm. The micropower operation, direct digital readout, and integration of electrical stimulation circuits make this interface ideally suited for closed-loop neuromodulation applications.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"10 1","pages":"990-1002"},"PeriodicalIF":5.1,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2016.2614845","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62966408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 410-nW efficient QRS processor for mobile ECG monitoring in 0.18-μm CMOS","authors":"Peng Li, Hanjun Jiang, Wendi Yang, Ming Liu, Xu Zhang, Xiaohui Hu, B. Pang, Zhaolin Yao, Hongda Chen","doi":"10.1109/BioCAS.2016.7833713","DOIUrl":"https://doi.org/10.1109/BioCAS.2016.7833713","url":null,"abstract":"This paper proposes a low power and efficient QRS processor for real-time and continuous mobile ECG monitoring. The QRS detection algorithm is based on the harr wavelet transform. In order to reduce power consumption, an optimized FIR filter structure is proposed. To improve accuracy, R position modification (RPM) has been designed. Fabricated with the 0.18-μm N-well CMOS 1P6M technology, power consumption of this chip is only 410 nW in 1 V voltage supply, which is much lower than that of previous work. Validated by all 48 databases in the MIT-BIH arrhythmia database, sensitivity (Se) and positive prediction (Pr) are 99.60% and 99.77% respectively.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"61 29 1","pages":"14-17"},"PeriodicalIF":5.1,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/BioCAS.2016.7833713","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62152832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}