journal of cardio-thoracic medicine最新文献

{"title":"Evaluation of the results and complications of posterior pericardiotomy in coronary artery bypass graft surgery at Farshchian Heart center in Hamadan","authors":"G. Safarpoor, Hosna Mohebbi, Mohammad Ali Seifrabyye, Aliasghar Moeinipour","doi":"10.22038/JCTM.2021.56283.1318","DOIUrl":"https://doi.org/10.22038/JCTM.2021.56283.1318","url":null,"abstract":"Introdution: Postoperative bleeding, pericardial effusion and arrhythmia (especially atrial fibrillation) are among the most common and important postoperative complications of CABG. Postoperative pericardial effusion can cause tamponade and also increases the incidence of atrial fibrillation. Posterior pericardiotomy is performed to reduce the incidence of pericardial effusion and its complications. This study aimed to investigating the results of posterior pericardiotomy in coronary artery bypass grafting surgery. Material and Methods: In this descriptive / cross-sectional study, 145 patients undergoing coronary artery bypass grafting at Farshchian Heart center from March 2019 until March 2020 were selected by convenience and consecutive sampling method and examined for early results of posterior pericardiotomy. Data were analyzed using SPSS software version 16 at 95% confidence level. Results: The mean age of patients was 63.96 years, 75.2% were male and 24.8% were female. 91% of operations were elective and 55.9% were on pump CABG .The incidence of postoperative Atrial fibrillation was 9.66%, pericardial effusion was seen in 3.36%patients, which was mild in 2.67% and moderate in.69%cases.Tamponade was not seen in any case .The overall mean drainage of all chest drains from the beginning to the time of drain removal, was about 795±409 cc. Conclusion: Posterior pericardiotomy is a simple and safe method of draining posterior pericardial space that may be effective in reducing the incidence of atrial fibrillation, pericardial effusion and pleural effusion after coronary artery bypass grafting","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128827145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A first description of benign metastasizing leiomyoma of the lung from madagascar: A brief review of the literature","authors":"N. Razafimanjato, R. A. Ralaivao, L. Nomenjanahary, Clarette Raharisolo Vololonantenaina, N. Randrianjafisamindrakotroka, H. Rakotovao","doi":"10.22038/JCTM.2021.56667.1322","DOIUrl":"https://doi.org/10.22038/JCTM.2021.56667.1322","url":null,"abstract":"Benign metastatic leiomyoma (BML) spreading in the lung is rare entities predominantly in a young woman. To our knowledge, our observation is the first description of benign metastasizing leiomyoma of the lung from Madagascar.We describe a case of 44-year-old of Malagasy origin, asymptomatic, non-smoking woman who had a history of hysterectomy for myoma three years earlier. Chest computed tomography (CT) revealed multiple well defned nodular shadows in the lung. One tumor of the middle lobe was resected by lateral thoracotomy. The resected lesion consisted of benign spindle cells and was diagnosed as BML. Through this clinical case, we present the first case report of a BML patient from Madagascar. The aim of this article is to take stock of the knowledge relating to this rare affection, and to propose management in accordance with the current literature","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134610197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of physical activity and obesity on hypertension: A narrative mini-review of the main effective mechanisms","authors":"S. Rahmati-Ahmadabad, F. Hosseini, A. Khalaj, Kiarash Mahdavi, Mahmood Omrani","doi":"10.22038/JCTM.2021.56560.1320","DOIUrl":"https://doi.org/10.22038/JCTM.2021.56560.1320","url":null,"abstract":"Physical activity (PA) and obesity are effective interventions for hypertension. The current study is a review to explain possible mechanisms related to the effects of PA and obesity on hypertension. To this end, several scientific databases were searched using the keyword \"hypertension\" and also some English articles related to obesity and PA were investigated. Then, the mechanisms of obesity and PA associated with hypertension were extracted from the collected articles. Overall, obesity causes an increase in renin-angiotensin-aldosterone (RAA) systems, harmful changes in lipid and lipoprotein profile, a decrease in insulin sensitivity, as well as harmful changes in adipokines, oxidative stress, and inflammatory factors. PA improves the above-mentioned changes caused by obesity. Overall, PA mainly via an effect on oxidative stress, inflammation, endothelial cells, the elasticity of arteries, body weight, the activity of the RAA system, activity of parasympathetic and renal function as well as improve the insulin sensitivity has positive effects on hypertension. It should be noted that the effects of PA against hypertension is highly variable and they are related to PA modes, environmental and genetic factors.","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114622162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Severe Mitral Regurgitation due to Papillary Muscle Rupture after Blunt Chest Trauma: Case Report","authors":"Y. Mubarak","doi":"10.22038/JCTM.2021.56406.1319","DOIUrl":"https://doi.org/10.22038/JCTM.2021.56406.1319","url":null,"abstract":"Cardiac injury is a common unexpected injury with high rate of mortality in multi-trauma patients. Blunt thoracic trauma leading to heart injury presented with variable presentations from myocardial contusion to rupture. Cardiac injury is about 15% - 25% of blunt chest trauma. Cardiac contusion is the most common type of injury with variable manifestations associated with electrocardiogram (ECG) changes or cardiac enzyme abnormality. Traumatic rupture of intra-cardiac structures after blunt Thoracic trauma is an uncommon. Cardiac valves rupture is uncommon, and the most frequent being aortic valve, and then followed by mitral and tricuspid. Nowadays, the incidence of these types of injury is increasing due to high increase of road traffic accidents (RTA). Following blunt thoracic trauma, rupture of papillary muscle or its chordae tendineae is a very rare causing acute mitral regurgitation (MR) with sequence of congestive heart failure (HF) and pulmonary edema.","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117135966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Utility of Cancer ratio (serum LDH: pleural fluid ADA) for predicting malignancy in patients with exudative pleural effusion” .","authors":"Bhaskar Kakarla, Varaprasad Kuruva, S. Deme, Sekhar Babu, Banda, N. Narahari, Paramjyothy Gongati Kruparao","doi":"10.22038/JCTM.2021.55782.1317","DOIUrl":"https://doi.org/10.22038/JCTM.2021.55782.1317","url":null,"abstract":"Introduction:Pleural effusion is an accumulation of fluid in the pleural space. It can be transudative or exudative. Mechanisms like alteration in Starling’s forces lead to transudative effusions while inflammation and infiltration by infections, malignancy, connective tissue diseases, etc lead to exudative effusions. Nearly 40% of patients with malignancy have pleural effusion at the time of presentation. Bronchogenic carcinoma, carcinoma of the breast, lymphoma are the leading causes of malignant pleural effusion(MPE) followed by gastrointestinal, genitourinary, and gynecological causes. Pleural fluid Adenosine DeAminase(ADA) has good diagnostic sensitivity and specificity for tuberculosis whereas pleural fluid cytology /biopsy are the main diagnostic modalities for MPE. However pleural fluid cytology is positive in only 48.5% of cases in the first sample but the yield increases with repeated analysis or other more invasive investigations like blind pleural biopsy/thoracoscopy. In cases with negative pleural fluid cytology, a biochemical marker known as Cancer ratio i.e serum LDH and pleural fluid ADA can be useful in predicting malignant causes. A cancer ratio cutoff of more than 20 helps in guiding the physician for further workups like FDG PET or tumor markers in evaluating malignancies. With this background our study aimed at the usefulness of cancer ratio in patients with exudative pleural effusion.Materials and Methods: It's a prospective observational study done for a period of 18months.100 adult patients with exudative pleural effusions were recruited. Serum LDH, pleural fluid ADA was done in all cases and the cancer ratio is validated for diagnosis of malignant effusions. Results: The mean age of patients was 55.48±9.32 years. There were 57 malignant and 43 nonmalignant cases. Bronchogenic carcinoma was the leading cause of MPE and tuberculosis was the commonest cause of non-malignant pleural effusions. Mean serum LDH, Pleural fluid ADA, and cancer ratio in malignant cases and nonmalignant cases was 434.54 and 350.04IU/ml,19.05 and 32.97IU/ml and 25.13, 20.45 respectively. The sensitivity of cancer ratio was 70.17%, specificity was 76.74%.Conclusions: Cancer ratio is an easy and valid diagnostic tool in suspecting malignant pleural effusions with good sensitivity and specificity.","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122936089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dramatic Improvement of Adult Patients with Post Tuberculosis Pulmonary Pneumatocele and Bad Pulmonary Function after Surgical Intervention.","authors":"Y. Mubarak","doi":"10.22038/JCTM.2021.55436.1311","DOIUrl":"https://doi.org/10.22038/JCTM.2021.55436.1311","url":null,"abstract":"Pulmonary pneumatoceles (PCs) are thin-walled, air-filled cysts that develop within pulmonary parenchyma. PCs are usually seen in the lung after infection, trauma. In case of infection, as a complication of acute pneumonia, caused by Staphylococcus aureus, and are more frequently in infants and children. Adult tuberculous pulmonary pneumatoceles are seldom reported [1]. PCs are usually asymptomatic. Large PCs may compress adjacent lung with mediastinal shift causing respiratory or cardiovascular symptoms [2]. Surgical intervention is only indicated when PCs cause cardiopulmonary compromise or rupture into the pleural space or unresolved infection [3].","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133747373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Pulmonary Fibrosis and Emphysema: A Case Report and Literature Review","authors":"Shaghayegh Badriahmadi, Mahnaz Mozdourian","doi":"10.22038/JCTM.2021.55771.1316","DOIUrl":"https://doi.org/10.22038/JCTM.2021.55771.1316","url":null,"abstract":"The syndrome of combined emphysema of the upper lobes and fibrosis of the lower lobes on chest computed tomography results in a characteristic functional profile, with preserved lung volumes, hypoxemia at exercise. Despite subnormal spirometry, combined pulmonary fibrosis and emphysema is a severe entity. The presence of pulmonary arterial hypertension at diagnosis is a critical determinant of prognosis.","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114962527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Aerobic Training and Pumpkin Seed Extract Consumption on the Heart and Aorta Oxidative Stress Biomarkers: A Case of Rats Exposed With Arsenic","authors":"Mahdi Badkoobeh Hezaveh, B. Abedi, S. Rahmati-Ahmadabad","doi":"10.22038/JCTM.2021.55557.1315","DOIUrl":"https://doi.org/10.22038/JCTM.2021.55557.1315","url":null,"abstract":"Introduction: It has beenproposed that regular aerobic exercisetraining and medicinal plants are able to reduce oxidative damage resulted from toxin metal poisoning such as arsenic which is a significant risk factor in the heart diseases. The purpose of this research is to evaluate the simultaneous effect of regular aerobic exercise training and pumpkin extract on oxidative stress of the heart and endothelial cells of the aorta in rats poisoned with arsenic. Materials and Methods: 56 male Wistar rats were divided into seven groups including TC (toxic control); AE (aerobic exercise training); TAP1 (toxic aerobic exercise training + 300 mg/kg/day pumpkin seed extract consumption); TAP2 (toxic aerobic exercise training + 600 mg/kg/day pumpkin seed extract consumption); TP1 (300 mg/kg/day toxic pumpkin seed extract consumption); TP2 (600 mg/kg/day toxic pumpkin seed extract consumption), and HC (healthy control). The intervention was performed based on the groups' categorization.  24 hours after the last intervention the samples were collected. Statistical analyses were performed using one and two-way analysis of variance (ANOVA). Results: The results showed that exercise training increased GSH (p= 0.0001) and GSSG (p= 0.0001) and declined MDA levels (p= 0.0001) in the aortic endothelial cells and heart tissue. Also, pumpkin seed extract consumption induced a significant increase in GSH (p= 0.0001) and GSSG (p= 0.0001) and decreased MDA levels (p= 0.0001) in the aortic endothelial cells and heart. On the other hand, interaction of exercise training and pumpkin seed extract consumption increased GSH (p= 0.0001) and GSSG (p= 0.0001) and decreased MDA levels (p= 0.0001) in the aortic endothelial cells and heart. Conclusion:It is concluded that concurrent of pumpkin seed extract consumption and aerobic exercise training could intensify mutual antioxidant effects in oxidative stresses such as cardiac disorders caused by arsenic poisoning.","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115636809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effects of Letrozole in Combination with Neoadjuvant Chemotherapy on Clinical Response Rate of Breast Cancer","authors":"Zahra, Mozahheb, Abolghasem, Alahyari, Seyyedeh, Fatemeh, Seyyedi, Khabbaz, A. Fattahi, Mohsen Najafi","doi":"10.22038/JCTM.2021.55048.1309","DOIUrl":"https://doi.org/10.22038/JCTM.2021.55048.1309","url":null,"abstract":"AbstractThis randomized clinical trial was aimed to assess the efficacy of neoadjuvant letrozole in combination with standard neoadjuvant chemotherapy regimen on clinical response rate of hormone receptor positive locally advanced breast cancer.In this randomized clinical study, 42 female patients, ≥ 18 years, with clinical stage IIB-IIIC (T1-4, N0-3, M0), pathologically proven hormone receptor positive and HER2 negative, invasive ductal carcinoma of breast, were randomly assigned to receive standard neoadjuvant chemotherapy alone (control group) or letrozole 2.5 mg/d (in association with goserlin in premenopausal patients) concurrent with standard neoadjuvant chemotherapy (study group). Standard neoadjuvant chemotherapy regimen has consisted of 4 cycles of doxorubicin (60mg/m2) and cyclophodphamide (600mg/m2), followed by 4 cycles of paclitaxel (175mg/m2) every two weeks.At the beginning of the study all patients underwent thorough exmination of breast mass and axillary lymph nudes by palpation and ultrasonography. At the end of the study response rates were also evaluated by palpation and ultrasonography and subsequently patients were referred for surgury. Pathologic response rates were also evaluated on surgical specimens. All of the clinical, ultrasonographic and pathologic examinations during the trial were performed by a single specialist. Finally all the data were analysed statistically.Overall clinical response rates in breast were 95.2%, in both study and control group. Overall clinical response rates in axilla were 80.9% and 76.2% in study and control group respectively. Similarly, overall radiologic complete response rates in breast and axilla were 95.2% and 76.2% respectively in both study and control group. Totally, the comparison of overall clinical and radiologic response rates in th breast and axilla, showed no significant difference between control and study group (p>0.05).The addition of letrozol to standard neoadjuvant chemotherapy regimen was not associated with higher clinical and radiologic response rates in patients with locally advanced hormon receptor positive breast cancer.Keywords: Neoadjuvant chemotherapy, Letrozole, Locally advanced breast cancer","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115278156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension and Its Risk Factors in the Population Covered by Mashhad University of Medical Sciences","authors":"Nasrin Milani, Ehsan Mosa Farkhani, Mohamad Sajjadi-Manesh, A. Taghipour, R. Ahmadi, K. Saeedi","doi":"10.22038/JCTM.2021.52881.1301","DOIUrl":"https://doi.org/10.22038/JCTM.2021.52881.1301","url":null,"abstract":"Introduction:  Hypertension is recognized as one of the major causes of cardiovascular disease. The present study aimed to assess the relationship between hypertension and its risk factors in the population referring to comprehensive health care centers affiliated to Mashhad University of Medical Sciences. Materials and Methods: This case-control study was performed on the health assessment data of the population aged 30 years and above registered in the SINA system in 2017-2018. The present case-control study was conducted on 1500 cases who were selected by systematic random sampling and assigned to the case group (500 hypertensive patients) and control group (1000 subjects without a history of hypertension). Data were analyzed using SPSS software (version 22). A p-value less than 0.05 was considered statistically significant. Results: Based on the results, the risk factors for hypertension included settlement in urban areas (OR=2.914), body mass index≥ 25 (OR = 2.522), waist circumference˃90 (OR=2.409), sedentary lifestyle (OR=2.373), consumption of solid oil (OR=1.581), triglyceride level of ˃150 (OR=566), use of table salt (OR=1.547). On the other hand, the following were identified as protective factors against hypertension: hard labor jobs (OR=0.292), optimal physical activity (OR=0.421), and regular consumption of vitamin D (OR=0.625) (p <0.05). Conclusion: The results will not only provide a solid foundation on potency of risk factors and protective factors for hypertension but will also give an invaluable insight to the health planning programs. The reduced prevalence of hypertension can be planned for with the identification of related risk and protective factors.","PeriodicalId":131413,"journal":{"name":"journal of cardio-thoracic medicine","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121585732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}