Gastroenterology: Medicine & Research最新文献

{"title":"Three Cases of Intentional Ingestion’s of Intact Cellular Phones Retrieved from the Gastrointestinal Tract","authors":"B. Koslowsky","doi":"10.31031/gmr.2021.06.000640","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000640","url":null,"abstract":"Gastroenterologists frequently encounter foreign body ingestions. Most accidental ingestions in adults are secondary to impactions of food boluses, primarily meat. Intentional ingestions in adults are usually by patients with psychiatric problems or drug abuse [1]. Foreign bodies can enter the rectum either secondary to ingestion or by direct anal insertion. A few case reports of telephone ingestions have been reported by patients with psychiatric disorders [2,3]. We present three cases of prisoners who intentionally swallowed or inserted small cellular telephones. The cell phones were either endoscopically or manually removed. All patients provided consent prior to the phone removal procedure.","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129897480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biliary Lithiasis and Subclinical Hypothyroidism: Myth or Truth?","authors":"S. Bouomrani","doi":"10.31031/gmr.2021.06.000638","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000638","url":null,"abstract":"With an average prevalence in the general population at 4-15% and more than 20% in the elderly, Subclinical Hypothyroidism (SCH) is the most common thyroid dysfunction. The clinical and biological impact of SCH is sometimes atypical, unusual, and very challenging in current medical practice. Among these atypical manifestations of SCH, some publications have suspected a particularly promoting role in the genesis of biliary lithiasis. The purpose of this review is to clarify the relationship between this thyroid dysfunction and gallstones. The systematic review of the literature allows us to conclude that the association between biliary lithiasis and SCH is far from mere chance. Diminished bile secretion, decreased liver cholesterol metabolism, and reduced sphincter of Oddi relaxation are the mechanisms involved in the formation and accumulation of biliary stones in subjects with S CH. Thus systematic screening for SCH is highly recommended in any patient diagnosed with biliary lithiasis.","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128064316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flat Squamous Papilloma in Esophagus A Complication Associated with Gerd? About A Case","authors":"G. Hernández","doi":"10.31031/gmr.2021.06.000639","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000639","url":null,"abstract":"The clinical case of a 25-year-old male patient is presented, with a history of abundant intake of spicy 3-4 times a week, intake of alcoholic beverages 8 ounces on average per week he comes to a medical consultation for presenting heartburn and regurgitation of 3 months of evolution he had been treated by a family doctor with omeprazole, metoclopramide and trimebutine 200mg, without improvement, in the last two weeks low dysphagia was added to solid food, reason for consulting a specialist doctor. He is instructed to perform panendoscopy with biopsy, which reports grade “C” esophagitis, exophytic lesion with smooth edges, pale pink, well delimited around 1.5cm long linear erosion, soft consistency (Figure 1) and smooth after taking biopsies, located in the lower third of the esophagus, as well as follicular gastropathy located in the antrum, biopsies were also taken from this area in separate vials; the histopathological report of the biopsies of the esophageal lesion in the microscopic description mentions papillary projections with fibrovascular axes covered by nonkeratinized stratified flat epithelium with areas of erosion and recent hemorrhage, (Figure 2) concluding flat squamous papilloma, chronic esophagitis due to grade reflux II, without evidence of dysplastic changes and/or Barrett. Gastric biopsies reported chronic gastritis of the follicular variety with moderate activity associated with infection by Helicobacter pylori bacilli in moderate quantity. After panendoscopy, he was prescribed levopantoprazole 20mg twice a day for 8 weeks, hygienic dietary measures for gastroesophageal reflux disease, with good response to symptoms, control endoscopy was performed at 12 weeks with endoscopic improvement of the lesion (Figure 3).","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133398044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastrointestinal Disorders and Psychology","authors":"Mariela González Tovar","doi":"10.31031/gmr.2021.06.000637","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000637","url":null,"abstract":"Both depressive-anxiety symptoms and psychosocial stressors are elements involved in gastrointestinal disorders [1]. What is debatable is to clarify what is the role of these factors, either as consequence or as cause in the appearance, or in the recurrence of these diseases. It can be considered that in some cases there are symptoms where there is no structural injury, but they are of emotional origin; and others in which the psychic manifestations are only a repercussion of a primary gastrointestinal disease [1]. In the first case, it is obvious that the emotional component is essential in the onset, maintenance, and relapses of the disorder, and when there is organic injury, a disease that can occur autonomously is established. In the case of primary diseases, where a psychic etiology has not been demonstrated, it cannot be ignored that psychic factors can influence vulnerability to contracting diseases, since the organism varies its balance in the face of stress [2]. Current knowledge has not yet clarified the relationship between psychic factors and their organic impact. Over the past 30 years, human research has proposed a clinical relationship between stressful life events and higher rates of morbidity and mortality [2]. In the field of Gastroenterology, these studies are even more confusing, because they vary with respect to whether the variable under study is the beginning of the disease, the appearance of symptoms or the clinical presentation [3]. While, in the field of Psychology, one is usually more interested in the way in which environmental factors and behavior modify a patient’s illness. Once an illness is established, cultural and family norms, as well as the psychological state and existential circumstances causing stress must be taken into account, since they tend to modify the behavior of the disease and perhaps even the disease itself. This is how social support and coping strategies can cushion these effects [4-6].","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127906655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leyomioma of the Gallbladder An Extremely Uncommon Diagnosis A Case Report","authors":"Carlos Enrique Luna-Guerrero","doi":"10.31031/gmr.2021.06.000636","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000636","url":null,"abstract":"Mesenchymal gallbladder neoplasms are sporadic; individually, very few gallbladder leiomyoma cases have been described, and all of them are diagnosed in patients with diseases of the immune system. A case report of a vesicular leiomyoma is described in a 41-year-old male patient without immune compromise. The patient lacked a significant past medical history and presented to the general surgery outpatient clinic with clinical data of acute cholecystitis and an ultrasound that reported cholelithiasis with no acute findings. It was sent to the emergency department for evaluation. Laboratory studies were performed, and the abdominal ultrasound was repeated, persistent symptoms were the primary indication to perform a laparoscopic cholecystectomy. He was discharged after clinical improvement after five days of hospital stay. Subsequent immunohistochemical study of the gallbladder specimen yielded the diagnosis of leiomyoma of the gallbladder fundus, with a positive SMA marker.","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130321117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuromodulators for Functional Dyspepsia-A Gut-Brain Interaction Disorder: Uptodate Clinical Practice","authors":"Georgios Zacharakis","doi":"10.31031/gmr.2021.06.000634","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000634","url":null,"abstract":"Functional dyspepsia significantly affects the quality of life and is a major cause of economic burden on both the patient and society. Adherence to international guidelines for the management of dyspepsia is crucial to avoid unnecessary procedures and medications. However, many countries have not assessed functional dyspepsia symptoms as defined by the ROME IV diagnostic criteria. Current clinical practices differ among countries, especially regarding the use of neuromodulators despite the recommended use of these drugs according to recent guidelines. There are also clinical differences between FD variants and different treatment regimens.","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129503477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Statins in the Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)","authors":"H. B","doi":"10.31031/gmr.2021.06.000633","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000633","url":null,"abstract":"Pancreatic ductal adenocarcinoma (PDAC) is a common cause of cancer-related mortality [1]. Moreover, a majority of patients (80%) are diagnosed at an advanced stage at presentation precluding surgical resection which is the mainstay of curative treatment options [1,2]. Multi-agent chemotherapy has been developed in recent years and have shown improved survival rates, even in patients with locally advanced and metastatic tumours [3,4]. In addition, adjuvant chemotherapy has also conferred a survival advantage in patients with resected pancreatic cancer [5,6]. However, despite these developments, PDAC related mortality remains high, with a 5 year survival rate of 6 7% across all stages [7,8]. This has Crimson Publishers Wings to the Research Research Article","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115019673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of an Incisional Hernia Protocol at the Municipal Public Server Hospital of Sao Paulo, Brazil: A Retrospective Study","authors":"João Kleber de Almeida Gentile","doi":"10.31031/gmr.2021.06.000632","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000632","url":null,"abstract":"Background and Aim: Abdominal Incisional Hernias (AIH) are a frequent complication in medium incisions that lead to a decrease in life quality, socioeconomic losses and increased morbidity to those who have it. Self-care cost for patients evolving with AIH can increase from 97% up to 370% in the first 3 years postoperatively. Regarding this, the Digestive System Surgery Service of the Municipal Public Server Hospital’s (HSPM) has created a protocol to deal with this type of patient since 2015, it has been applied up to the present moment. Incisional hernias result from a multifactorial process that includes preoperative factors such as the cessation of smoking, diabetes control, and obesity, such factors affect the proper functioning of the early stages of the healing process. Patient and Method: Retrospective study with registry analysis of medical records and database records created on cloud regarding perioperative information and outcomes of 35 patients with complex incisional hernias treated under the protocol of patient care for incisional hernia on the Municipal Public Server Hospital (Attachment 1) by the Digestive System Surgery Service, between 2015 and 2019. Result: In our analysis of 35 patients operated by the Digestive System Surgery Team in the period from 2015 to 2019, the average of hospital stay was 4.55 days per patient, with a total of 22.857% of complications, from seromas without serious repercussion to a wall infection which demanded debridement and reassessment for cutaneous flap. Onlay meshes were used in 57.14% of the cases, 37.14% were sublay meshes, and in two cases (5.71%) meshes were placed in two different planes, sublay and onlay - sandwich technique. Of these cases, one was a lateral hernia by multiple procedures and the other was caused by a late postoperative of lumbotomy with lateral hernia evolution. There was a recurrence of a patient with a 6.9cm hernia, he underwent two treatment attempts in 2005 and 2010, which also presented recurrence. In our service the patient was treated with the Rives-Stoppa technique. The patient chose not to undergo further treatment. Conclusion: The protocol application to patients with AIH was associated with a recurrence rate of 2.86%, in a universe of patients in which recurrence still remains a feared complication for both the surgeon and the patient. Furthermore, the complications were treated, most of them successfully, with clinical measures, except for a recurrence and a surgical wound infection in which debridement was necessary, adding up to 5.71%.","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"339 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134505298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastroparesis and Symptoms-Sketchy Relationships","authors":"F. T.","doi":"10.31031/gmr.2021.06.000631","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000631","url":null,"abstract":"The relation between gastric emptying and symptoms is still unclear. The conception that improvement of gastric outflow or motoric function by Gastric Peroral Endoscopic Pyloromyotomy (G-POEM) or Gastric Electrical Stimulation (GES) would improve gastrointestinal symptoms simplifies the complexity of gastric dysfunction. It is still unclear why some patients with gastroparesis and dyspeptic symptoms benefit from GES. Besides placebo effects alteration of visceral perception has been suggested.","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128394809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gallbladder Tumor Treated Through Chemotherapy: A Case Report","authors":"João Kleber de Almeida Gentile","doi":"10.31031/gmr.2021.06.000630","DOIUrl":"https://doi.org/10.31031/gmr.2021.06.000630","url":null,"abstract":"The Gallbladder neoplasia is rare and has a high mortality rate, thus surgery is still the usual curative treatment for the disease. Once its diagnosis is usually tricky and at a late stage, there is the necessity of using neoadjuvant chemotherapy in advanced cases. We report the case of a 51-year-old man diagnosed with gallbladder cancer presenting liver invasion but no metastasis. Initially, it was considered inoperable so the patient was submitted to neoadjuvant chemotherapy with gemcitabine. By the end of chemotherapy, the radiological examination showed the complete reduction of the lesion, choosing to proceed with the salvage surgery. Therefore, it was performed conventional cholecystectomy with liver resection (segments V and VI) and regional lymphadenectomy. The histopathological examination did not show neoplasia in any of the resected tissues or lymph nodes involvement. The patient evolved to the cure of the disease with chemotherapy","PeriodicalId":130011,"journal":{"name":"Gastroenterology: Medicine & Research","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132676189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}