Flat Squamous Papilloma in Esophagus A Complication Associated with Gerd? About A Case

G. Hernández
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Abstract

The clinical case of a 25-year-old male patient is presented, with a history of abundant intake of spicy 3-4 times a week, intake of alcoholic beverages 8 ounces on average per week he comes to a medical consultation for presenting heartburn and regurgitation of 3 months of evolution he had been treated by a family doctor with omeprazole, metoclopramide and trimebutine 200mg, without improvement, in the last two weeks low dysphagia was added to solid food, reason for consulting a specialist doctor. He is instructed to perform panendoscopy with biopsy, which reports grade “C” esophagitis, exophytic lesion with smooth edges, pale pink, well delimited around 1.5cm long linear erosion, soft consistency (Figure 1) and smooth after taking biopsies, located in the lower third of the esophagus, as well as follicular gastropathy located in the antrum, biopsies were also taken from this area in separate vials; the histopathological report of the biopsies of the esophageal lesion in the microscopic description mentions papillary projections with fibrovascular axes covered by nonkeratinized stratified flat epithelium with areas of erosion and recent hemorrhage, (Figure 2) concluding flat squamous papilloma, chronic esophagitis due to grade reflux II, without evidence of dysplastic changes and/or Barrett. Gastric biopsies reported chronic gastritis of the follicular variety with moderate activity associated with infection by Helicobacter pylori bacilli in moderate quantity. After panendoscopy, he was prescribed levopantoprazole 20mg twice a day for 8 weeks, hygienic dietary measures for gastroesophageal reflux disease, with good response to symptoms, control endoscopy was performed at 12 weeks with endoscopic improvement of the lesion (Figure 3).
食管扁平鳞状乳头状瘤是胃反流的并发症吗?关于一个案例
临床病例为25岁男性患者,每周大量摄入麻辣3-4次,平均每周摄入酒精饮料8盎司,因胃灼热和反流3个月来就诊,由家庭医生治疗奥美拉唑、甲氧氯普胺和曲美布汀200mg,无改善,最近两周添加低吞咽困难固体食物。咨询专科医生的理由。指示患者行全内镜活检,结果为“C”级食管炎,外生性病变边缘光滑,淡粉色,界线清晰,约1.5cm长线状糜烂,软质粘连(图1),活检后光滑,位于食管下三分之一,位于胃窦滤泡性胃病,也分别在该区域取活检;镜下食管病变活检的组织病理学报告显示,乳头状突出,纤维血管轴被非角化的分层扁平上皮覆盖,有糜烂和近期出血区域(图2),结论是扁平鳞状乳头状瘤,II级反流引起的慢性食管炎,无发育异常改变和/或Barrett的证据。胃活组织检查报告慢性滤泡型胃炎与幽门螺杆菌感染有关。全内镜检查后给予左旋泮托拉唑20mg,每日2次,连用8周,采取卫生饮食措施治疗胃食管反流病,症状缓解良好,12周控制性内镜检查,内镜下病变改善(图3)。
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