Health SecurityPub Date : 2026-01-01Epub Date: 2026-02-12DOI: 10.1177/23265094261418814
Alex Zhu, William P Bahnfleth, Richard Bruns, Giorgio Buonanno, David Fisman, Cria O Gregory, Charles N Haas, Benjamin Jones, Kazukiyo Kumagai, Georgia K Lagoudas, Yuguo Li, Alexander Linder, Donald Milton, Lidia Morawska, Scott W Olesen, Paula Olsiewski, Lew Radonovich, Pawel Wargocki, Gigi K Gronvall
{"title":"Breaking Down Silos: A Multidisciplinary Approach to Mitigate Indoor Airborne Pathogen Transmission.","authors":"Alex Zhu, William P Bahnfleth, Richard Bruns, Giorgio Buonanno, David Fisman, Cria O Gregory, Charles N Haas, Benjamin Jones, Kazukiyo Kumagai, Georgia K Lagoudas, Yuguo Li, Alexander Linder, Donald Milton, Lidia Morawska, Scott W Olesen, Paula Olsiewski, Lew Radonovich, Pawel Wargocki, Gigi K Gronvall","doi":"10.1177/23265094261418814","DOIUrl":"10.1177/23265094261418814","url":null,"abstract":"<p><p>Addressing indoor air quality (IAQ) is essential for reducing respiratory disease risks. In this commentary, we highlight the need for increased connections between typically siloed engineering and health disciplines to tackle remaining IAQ knowledge gaps that, if closed, would enhance IAQ applications and health. We provide actionable insights for policymakers, building designers, and funding agencies, recommending multidisciplinary research to support (1) increasing understanding of the complex and multifactorial variables in human infection, (2) using physical and mathematical models to understand disease transmission, and (3) determining the effectiveness of layered interventions in different environments. Addressing these knowledge gaps will help in the delivery of cost-effective IAQ solutions that reduce infectious disease risks in workplaces, schools, homes, and other indoor environments.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":" ","pages":"7-14"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2026-01-01Epub Date: 2026-02-27DOI: 10.1177/23265094251412396
Segaran P Pillai, Tanya Pittas, Adrienne Phifer
{"title":"Fundamentals of a Laboratory Security Program in Biomedical Facilities.","authors":"Segaran P Pillai, Tanya Pittas, Adrienne Phifer","doi":"10.1177/23265094251412396","DOIUrl":"10.1177/23265094251412396","url":null,"abstract":"<p><p>Laboratory security is a vital component of institutional laboratory operations. While hazardous biological agents and toxins are inherent to a biomedical institution, the chemicals and radiological materials used to support biomedical research goals have their own unique security requirements. The presence and use of these materials necessitates heightened security measures that must be followed to ensure adherence to federal and state regulations and the safety and health of an institution's employees and the surrounding environment. In this paper, we outline best practices, key considerations, and applicable institutional oversight measures related to laboratory security activities. The laboratory security components we describe are intended to help institutions implement, address, and mitigate the complex security risks associated with laboratory work in biomedical facilities. Leveraging these best practices can ensure a secure work environment by reducing risks of insider threats, intentional theft or misuse of laboratory materials, and release of sensitive information by restricting sensitive information and hazardous material access to only those who require or have a need for it.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":" ","pages":"77-86"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2026-01-01Epub Date: 2026-02-22DOI: 10.1177/23265094261424116
Kris M Belland, Charles A DeJohn
{"title":"Comprehensive Review: Ultraviolet-C (UVC) Disinfection in Aircraft Cabins.","authors":"Kris M Belland, Charles A DeJohn","doi":"10.1177/23265094261424116","DOIUrl":"10.1177/23265094261424116","url":null,"abstract":"<p><p>Ultraviolet-C (UVC) disinfection has gained considerable attention as a continuous, real-time method to mitigate the transmission of airborne pathogens within aircraft cabins. Recent investigations have demonstrated its potential to inactivate viruses such as SARS-CoV-2, influenza, and other emerging infectious agents in situ, thereby reducing both immediate infection risks and broader public health burdens. This commentary evaluates how continuous UVC disinfection-applied in tandem with established preventive measures-may effectively curtail disease transmission, reassure passengers, and inform the future direction of in-flight health and safety standards.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":" ","pages":"35-38"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147270757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2026-01-01Epub Date: 2026-02-06DOI: 10.1177/23265094261421824
Alexander G Linder, Alex W Zhu, Richard Bruns, Paula Olsiewski, Gigi K Gronvall
{"title":"Far UVC Technology and Germicidal Ultraviolet Energy: Policy and Research Review for Indoor Air Quality and Disease Transmission Control.","authors":"Alexander G Linder, Alex W Zhu, Richard Bruns, Paula Olsiewski, Gigi K Gronvall","doi":"10.1177/23265094261421824","DOIUrl":"10.1177/23265094261421824","url":null,"abstract":"<p><p>Far ultraviolet-C (UVC) is an emerging, flexible technology for indoor air disinfection with the potential to reduce airborne transmission of pathogens while maintaining safety for human tissues. Despite its high efficacy to neutralize a wide range of pathogens and safety for human tissues, implementation of far UVC is hampered by regulatory gaps, consumer uncertainty, and unanswered research questions surrounding the formation and interaction of generated ozone and volatile oxidative byproducts. This commentary describes targeted recommendations for both epidemic-where rapid far-UVC deployment and ability to counter a wide variety of pathogens in balanced with potential environmental impacts on the indoor environment-and long term implementation scenarios, highlighting the need for human health risk studies, regulatory guidance for fa- UVC devices, and real-world cost benefit analyses, which consider the tradeoffs long term of far UVC and germicidal ultraviolet implementation. Far-UVC technologies demonstrate an exciting opportunity to promote the benefits of germicidal UV disinfection to more indoor spaces. More research is needed, however, to ensure its safe and equitable use and development. This work was in part informed by a workshop held by the Johns Hopkins Center for Health Security, which convened experts from academia, government, and industry to evaluate the scientific and policy considerations for far UVC, comparing the new technology to traditional germicidal ultraviolet.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":" ","pages":"47-54"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2026-01-01Epub Date: 2026-02-22DOI: 10.1177/23265094261418815
Aurelia Attal-Juncqua, Anita Cicero, Alex Zhu, Tom Inglesby
{"title":"AIxBio: Opportunities to Strengthen Health Security.","authors":"Aurelia Attal-Juncqua, Anita Cicero, Alex Zhu, Tom Inglesby","doi":"10.1177/23265094261418815","DOIUrl":"10.1177/23265094261418815","url":null,"abstract":"<p><p>Artificial Intelligence (AI) has the potential to revolutionize biosecurity, health security, biodefense, and pandemic preparedness by offering groundbreaking solutions for managing biological threats. This landscape review explores recent advancements in AI across these fields, drawing from both grey literature and peer-reviewed studies published between January 2019 and February 2024. AI has demonstrated potential in predicting viral mutations, which could enable earlier detection of outbreaks, and streamlining resource allocation by analyzing diverse data sources. It could also play a crucial role in accelerating the development and deployment of medical countermeasures, such as vaccines and therapeutics. Additionally, use of AI may enhance laboratory automation, reducing human error and increasing biosafety. Despite these promising advancements, significant challenges related to the potential misuse of AI, data security, and privacy concerns necessitate careful implementation and robust governance. This article highlights the rapid progress and vast potential of AI in biosecurity and provides key recommendations for US policymakers to effectively harness AI's capabilities while ensuring safety and security. These recommendations include expanding access to advanced computing resources, fostering collaboration across sectors, and establishing clear regulatory frameworks to support the safe and ethical deployment of AI technologies.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":" ","pages":"66-76"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147270755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2026-01-01Epub Date: 2026-02-05DOI: 10.1177/23265094251410880
Georgia K Lagoudas, Sabrina M Chwalek, Natalie Kopp, Joshua M Wentzel, Ben C Snyder, Joseph G Allen, Elizabeth E Cameron
{"title":"Federal and State Policy Opportunities to Improve Indoor Air Quality.","authors":"Georgia K Lagoudas, Sabrina M Chwalek, Natalie Kopp, Joshua M Wentzel, Ben C Snyder, Joseph G Allen, Elizabeth E Cameron","doi":"10.1177/23265094251410880","DOIUrl":"10.1177/23265094251410880","url":null,"abstract":"<p><p>The United States has significant opportunities to ensure buildings have clean indoor air. Federal and state governments can promote health-based indoor air quality (IAQ) targets, provide guidance and technical assistance, fund ventilation improvements, incentivize or require IAQ standards in public buildings, and work alongside industry and state and local partners to promote best IAQ practices. Despite the demonstrated health, economic, and national security benefits of improved IAQ, there has been limited progress in advancing clean indoor air across buildings in the United States. There is no comprehensive roadmap for federal and state policy actions. In this commentary, we offer a suite of policy options to improve IAQ that focus on establishing health-based IAQ targets, supporting state and local actions to adopt IAQ standards and policies, implementing sector-specific guidelines, and expanding IAQ research and development. This paper presents a spectrum of policy approaches, recognizing that different jurisdictions and sectors will have unique needs and constraints.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":" ","pages":"25-34"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2026-01-01Epub Date: 2026-02-23DOI: 10.1177/23265094261418816
Kenneth B Yeh, Benjamin D Anderson, Elaine B Jarvis, Meng Kong, Gene G Olinger, Falgunee K Parekh, Ami Patel, Bradly G Setser, Jacob L Swett, Wai-Ling Mui
{"title":"Catch Me if You Can: Reducing Infectious Disease Through Better Indoor Air Quality and Biosurveillance.","authors":"Kenneth B Yeh, Benjamin D Anderson, Elaine B Jarvis, Meng Kong, Gene G Olinger, Falgunee K Parekh, Ami Patel, Bradly G Setser, Jacob L Swett, Wai-Ling Mui","doi":"10.1177/23265094261418816","DOIUrl":"10.1177/23265094261418816","url":null,"abstract":"<p><p>Infectious disease transmission continues to be an unmet challenge. This is in part due to the air that circulates within our indoor environments, which can contain a myriad of potentially pathogenic bacteria, fungi, mold, and viruses as well as various allergens. This issue was highlighted during the COVID-19 pandemic, due to the highly infectious nature of SARS-CoV-2 and the public measures taken to limit airborne transmission of the pathogen through quarantining, social distancing, and maskwearing. The broad disruption in normal activities and interactions within these indoor environments prompted rethinking how indoor air quality can be improved to further mitigate infectious disease transmission. There is opportunity to accomplish health security and biosurveillance for protecting critical building infrastructures by incorporating existing and new measures for detection and control of microbial burden. Integrating central building controls and systems for heating, ventilation, and air conditioning with ongoing detection of environmental flora and microbes can help identify emerging pathogens and endemic biothreats such as SARS-CoV-2 and Legionella, respectively. This effort, however, will require (1) synergistic funding from 1 or more government agencies and multiple commercial entities to maintain habitable indoor environments and (2) environmental factors on infectious disease emergence and transmission to improve health outcomes and overall national security. In this commentary, we illustrate the importance of indoor air quality through case studies of infectious pathogens, their interaction with indoor environments, and measures to curtail the airborne transmission of respiratory disease.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":" ","pages":"39-46"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2026-01-01Epub Date: 2026-04-01DOI: 10.1177/23265094261424702
Gigi Kwik Gronvall
{"title":"Indoor Air Quality: An Essential Ingredient for Health Security.","authors":"Gigi Kwik Gronvall","doi":"10.1177/23265094261424702","DOIUrl":"https://doi.org/10.1177/23265094261424702","url":null,"abstract":"","PeriodicalId":12955,"journal":{"name":"Health Security","volume":"24 1","pages":"5-6"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147591845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2025-11-01DOI: 10.1177/23265094251398059
Elizabeth L Beam, Jocelyn J Herstein, Kevin Kupzyk
{"title":"Exploring the Impact of Prerequisite eLearning on Respiratory Protection Equipment Safety Behaviors in Simulation Training.","authors":"Elizabeth L Beam, Jocelyn J Herstein, Kevin Kupzyk","doi":"10.1177/23265094251398059","DOIUrl":"https://doi.org/10.1177/23265094251398059","url":null,"abstract":"<p><p>Military healthcare workers (HCWs) face similar clinical challenges in providing care during the pandemic as the civilian workforce. The most common respirator used in healthcare is the N95 filtering facepiece respirator (FFR). Video scoring has been successful in describing the challenges HCWs face with transmission-based precautions in healthcare. This case study explores the critical safety behavioral outcomes of 2 training interventions for respiratory protective equipment use by military HCWs during a Center for Sustainment of Trauma and Readiness Skills course on biocontainment care in Omaha, Nebraska, at the University of Nebraska Medical Center. The study included a knowledge quiz and computer-based educational materials. Behavioral assessment was done by video recording and scoring skills performance during 3 donning and doffing N95 respirator opportunities in the training course. The main finding of the knowledge quiz was the gap in recognition that hand hygiene is warranted after the personal touching required when donning a respirator. The expert scoring of respirator use showed poor performance of critical safety behaviors such as performing the user seal check for the respirator. Training opportunities can be used for data collection related to respirator safety behavior change, but our investigators would recommend isolating the behavioral interest more than this case study was able to do. There were limitations in this project by the nature of combining this assessment with the training course and its dense curriculum. This investigation into respiratory protection equipment behavior interventions during a pandemic may provide for improvement in future educational and behavioral assessment activities.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":"23 6","pages":"456-463"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145722287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health SecurityPub Date : 2025-11-01DOI: 10.1177/23265094251396048
John M Drake, Justin Bahl, Michael A Cacciatore, Amin Ghadami, Ellie Graeden, Barbara A Han, Glen Nowak, Éric Marty, Hailey Robertson, Pejman Rohani, Sukanta Sarkar, Guppy L Stott, Amy K Winter, Bogdan I Epureanu
{"title":"Leveraging Systems-of-Systems Analysis to Strengthen Epidemic Intelligence for Preparedness and Response.","authors":"John M Drake, Justin Bahl, Michael A Cacciatore, Amin Ghadami, Ellie Graeden, Barbara A Han, Glen Nowak, Éric Marty, Hailey Robertson, Pejman Rohani, Sukanta Sarkar, Guppy L Stott, Amy K Winter, Bogdan I Epureanu","doi":"10.1177/23265094251396048","DOIUrl":"https://doi.org/10.1177/23265094251396048","url":null,"abstract":"<p><p>The COVID-19 pandemic exposed significant gaps in the coordination and integration of efforts required to effectively manage large-scale infectious disease outbreaks. A successful response to such crises demands the swift and ongoing synthesis of information and activities across multiple sectors, including government, healthcare, and private industry. However, these systems are often managed in isolation, leading to misaligned policies, fragmented communications, and inefficiencies that hinder pandemic response efforts. To address these challenges, we propose adopting a systems-of-systems (SOS) paradigm to enhance epidemic intelligence and improve preparedness and response during infectious disease emergencies. The SOS approach, widely used in engineering, offers a framework for integrating diverse fields such as virology, ecology, psychology, and policy. We illustrate the potential of this approach using highly pathogenic avian influenza (HPAI) as a case study and discuss key considerations for implementing SOS thinking in the context of global epidemic intelligence systems.</p>","PeriodicalId":12955,"journal":{"name":"Health Security","volume":"23 6","pages":"400-410"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145722383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}