Heart and Vessels最新文献_第6页

Low health literacy limits behavioral changes during phase I cardiac rehabilitation: a multicenter clinical study. 低健康素养限制了I期心脏康复期间的行为改变：一项多中心临床研究

IF 1.5 4区医学

Heart and Vessels Pub Date : 2025-07-29 DOI: 10.1007/s00380-025-02589-5

Yuji Kanejima, Kazuhiro P Izawa, Masahiro Kitamura, Kodai Ishihara, Asami Ogura, Ikko Kubo, Hitomi Nagashima, Hideto Tawa, Daisuke Matsumoto, Ikki Shimizu

{"title":"Low health literacy limits behavioral changes during phase I cardiac rehabilitation: a multicenter clinical study.","authors":"Yuji Kanejima, Kazuhiro P Izawa, Masahiro Kitamura, Kodai Ishihara, Asami Ogura, Ikko Kubo, Hitomi Nagashima, Hideto Tawa, Daisuke Matsumoto, Ikki Shimizu","doi":"10.1007/s00380-025-02589-5","DOIUrl":"https://doi.org/10.1007/s00380-025-02589-5","url":null,"abstract":"Cardiovascular diseases are strongly associated with poor lifestyle habits. Adopting healthier lifestyle habits is essential for reducing the risks associated with cardiovascular diseases. However, low health literacy (HL) may compromise assessing, using, and understanding health information, making modification of health behavior less likely. This study aimed to clarify the relationship between HL and changes in health behavior in inpatients undergoing cardiac rehabilitation. This was a multicenter cohort study of patients undergoing phase I cardiac rehabilitation. We used the 14-item Health Literacy Scale (HLS-14) to assess HL and the transtheoretical model (TTM) to assess changes in health behavior. Behavioral changes during hospitalization were defined using the stages of the TTM. A total of 428 patients who underwent cardiac rehabilitation (mean age: 73.0 years; males: 71.5%) were included. Evaluation of the behavioral changes exhibited by the participants revealed that the pre-contemplation stage (83.2%) was common at the beginning of rehabilitation, whereas contemplation (50.7%) and preparation (38.1%) stages were common at discharge. Of the 428 participants, 83.6% exhibited behavioral changes during hospitalization. Multivariate analysis revealed that HLS-14 score was a significant explanatory variable associated with changes in health behavior (odds ratio: 1.04; 95% confidence interval: 1.00-1.07). The spline curves modeling the relationship between HLS-14 score and changes in health behavior showed a positive correlation in the low HL group. HL is significantly correlated with changes in health behavior, especially in individuals with a low HL level.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144729856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of heparin anticoagulation on the antithrombogenicity of an extracorporeal membrane oxygenation system under veno-arterial bypass in an animal model. 肝素抗凝对静脉-动脉旁路下体外膜氧合系统抗血栓形成性的影响

IF 1.4 4区医学

Heart and Vessels Pub Date : 2025-07-26 DOI: 10.1007/s00380-025-02587-7

Futoshi Kobayashi, Tomohiro Nishinaka, Toshihide Mizuno, Tomonori Tsukiya, Motonobu Nishimura

{"title":"Effect of heparin anticoagulation on the antithrombogenicity of an extracorporeal membrane oxygenation system under veno-arterial bypass in an animal model.","authors":"Futoshi Kobayashi, Tomohiro Nishinaka, Toshihide Mizuno, Tomonori Tsukiya, Motonobu Nishimura","doi":"10.1007/s00380-025-02587-7","DOIUrl":"https://doi.org/10.1007/s00380-025-02587-7","url":null,"abstract":"An extracorporeal membrane oxygenation (ECMO) system consisting of a heparin-coated membrane oxygenator with polymethylpentene hollow fiber membranes and a heparin-coated hydrodynamically levitated centrifugal pump was developed. The effect of heparin anticoagulation on the antithrombogenicity of the ECMO system under veno-arterial bypass was evaluated in an animal model. Veno-arterial bypass with the ECMO system was induced in goats. Ten goats were evaluated which were divided into heparin anticoagulation-free (HPF; n = 5) and heparin anticoagulation (HP; n = 5) groups. Evaluation of the ECMO system focused on thrombus formation and changes in blood test data. Veno-arterial bypass with the ECMO system was maintained for 2 weeks in both groups. The extent of thrombus formation in the oxygenators was suppressed in the HP group. The centrifugal pumps were free of major thrombus formation in both groups. From baseline to postoperative day (POD) 1, both groups showed significant decreases in platelet counts, with a significant reduction in von Willebrand factor (vWF) activity levels in the HPF group. Between PODs 1 and 14, POD differences were observed in platelet counts without group or interaction differences. The levels of vWF activity showed significant group differences, with the HPF group demonstrating lower values than the HP group, but no significant POD or interaction differences. Veno-arterial bypass with the ECMO system was sustained for 2 weeks regardless of heparin anticoagulation. Heparin anticoagulation suppressed the extent of thrombus formation in the oxygenators. The centrifugal pumps were free of major thrombus formation regardless of heparin anticoagulation.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HELT-E2S2 score in ischemic stroke: a step forward in risk prediction, but gaps remain. 缺血性脑卒中的HELT-E2S2评分：在风险预测方面向前迈进了一步，但差距仍然存在。

IF 1.5 4区医学

Heart and Vessels Pub Date : 2025-07-23 DOI: 10.1007/s00380-025-02590-y

Brijesh Sathian, Javed Iqbal, Syed Muhammad Ali, Ayesha Parvaiz Malik

引用次数: 0

Clinical impact of increasing ratio from ^99mTc-sestamibi SPECT: validation by PET-myocardial flow reserve. 99mTc-sestamibi SPECT增加比值的临床影响：pet -心肌血流储备验证。

IF 1.4 4区医学

Heart and Vessels Pub Date : 2025-07-22 DOI: 10.1007/s00380-025-02588-6

Akihiro Inoue, Michinobu Nagao, Atsushi Yamamoto, Koichiro Kaneko, Akiko Sakai, Risako Nakao, Masaki Watanabe, Yurie Shirai, Junichi Yamaguchi, Shuji Sakai

{"title":"Clinical impact of increasing ratio from 99mTc-sestamibi SPECT: validation by PET-myocardial flow reserve.","authors":"Akihiro Inoue, Michinobu Nagao, Atsushi Yamamoto, Koichiro Kaneko, Akiko Sakai, Risako Nakao, Masaki Watanabe, Yurie Shirai, Junichi Yamaguchi, Shuji Sakai","doi":"10.1007/s00380-025-02588-6","DOIUrl":"https://doi.org/10.1007/s00380-025-02588-6","url":null,"abstract":"Myocardial flow reserve (MFR) obtained from 13N-ammonia PET is valuable for predicting the prognosis of patients with various heart diseases. The increase ratio (IR), a new parameter in 99mTc-sestamibi SPECT, is an indicator of the relative increase in blood flow during stress compared to rest, and the concept is similar to that of PET-MFR. We investigated the relationship between IR and PET-MFR as well as their clinical significance. Patients who underwent 13N-ammonia PET and 99mTc-sestamibi SPECT within one year of each other were enrolled and 33 patients (28 males, mean age 65.7 ± 12.9) were analyzed. Using adenosine stress and resting images of 99mTc-sestamibi SPECT, the stress image count was divided by the resting image count, and IR was calculated. We investigated the correlation between IR and PET-MFR and validated the optimal IR cutoff value for detecting PET-MFR < 1.6 by receiver operating characteristic (ROC) analysis. IR was significantly lower than PET-MFR (mean IR, 1.198; mean PET-MFR, 1.910; p < 0.0001) and positively correlated with PET-MFR (Pearson r = 0.3567; p < 0.01). ROC analysis indicated that the optimal IR cutoff value for detecting PET-MFR < 1.6 was 1.06, yielding an area under the curve (AUC) of 0.683, with 50% sensitivity and 83% specificity. By combining summed stress score with IR, the detectability of PET-MFR < 1.6 improved the AUC of 0.798 with 83% sensitivity and 70% specificity. IR was positively correlated with PET-MFR. This suggests that IR may be useful for detecting patients with a low MFR in facilities that do not perform 13N-ammonia PET.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myocardial injury in Duchenne muscular dystrophy: assessment via cardiac magnetic resonance intra-voxel incoherent motion. 杜氏肌营养不良的心肌损伤：通过心脏磁共振体素内非相干运动评估。

IF 1.4 4区医学

Heart and Vessels Pub Date : 2025-07-21 DOI: 10.1007/s00380-025-02580-0

Atsushi Yamamoto, Michinobu Nagao, Keiko Ishigaki, Minobu Shichiji, Yuki Kihara, Akiko Sakai, Yuichiro Minami, Yasuhiro Goto, Masami Yoneyama, Shuji Sakai, Junichi Yamaguchi

{"title":"Myocardial injury in Duchenne muscular dystrophy: assessment via cardiac magnetic resonance intra-voxel incoherent motion.","authors":"Atsushi Yamamoto, Michinobu Nagao, Keiko Ishigaki, Minobu Shichiji, Yuki Kihara, Akiko Sakai, Yuichiro Minami, Yasuhiro Goto, Masami Yoneyama, Shuji Sakai, Junichi Yamaguchi","doi":"10.1007/s00380-025-02580-0","DOIUrl":"https://doi.org/10.1007/s00380-025-02580-0","url":null,"abstract":"Duchenne muscular dystrophy (DMD) is a progressive myopathy caused by a mutation in the dystrophin gene. Cardiac disease is currently the leading cause of death in patients with DMD; thus, early diagnosis and management of cardiomyopathy are essential. Intra-voxel incoherent motion (IVIM) analysis provides quantitative values from diffusion-weighted imaging (DWI) and may serve as a novel index for evaluating myocardial properties in DMD. We conducted IVIM analysis in patients with DMD and compared their results with those of healthy volunteers to confirm that IVIM analysis can detect myocardial damage more effectively than conventional imaging methods. Patients with DMD who underwent cardiac magnetic resonance IVIM were enrolled. D and F values were measured using DWI of the left ventricle. Six healthy volunteers served as the control group. Twelve male patients with DMD were enrolled (median age, 14 years). Creatinine kinase levels were elevated, brain natriuretic peptide values remained within the normal range, and troponin T levels were only mildly elevated. The D value in patients with DMD was significantly higher than that in healthy volunteers, indicating increased diffusion in the myocardium (2.59 vs. 1.85, p = 0.0057); however, the F value was comparable between the two groups (0.62 vs. 0.61, p = 0.60). The D and F values from IVIM analysis provided a more detailed reflection of myocardial properties. Myocardial diffusion in patients with DMD was elevated compared with that in healthy volunteers.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144674558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of aerobic exercise habits with higher albumin-globulin ratio and lower cellular immune-inflammatory markers: implication of the preventive effect of aerobic exercise on atherosclerotic cardiovascular disease. 有氧运动习惯与较高的白蛋白-球蛋白比率和较低的细胞免疫-炎症标志物的关联：有氧运动对动脉粥样硬化性心血管疾病的预防作用的含义

IF 1.5 4区医学

Heart and Vessels Pub Date : 2025-07-19 DOI: 10.1007/s00380-025-02585-9

Leiying Zhang

引用次数: 0

The use of crista terminalis maximum interdeflection time for right-left determining in atrial flutter patients. 心房扑动患者使用终嵴最大偏转时间判断左右心房扑动。

IF 1.4 4区医学

Heart and Vessels Pub Date : 2025-07-18 DOI: 10.1007/s00380-025-02578-8

Yahya Kemal Icen, Hazar Harbalioglu, Mustafa Lutfullah Ardic, Fatih Sivri, Abdullah Eren Cetin, Elif Tunc, Hilmi Erdem Sumbul, Durmus Yıldıray Sahin, Mevlut Koc

{"title":"The use of crista terminalis maximum interdeflection time for right-left determining in atrial flutter patients.","authors":"Yahya Kemal Icen, Hazar Harbalioglu, Mustafa Lutfullah Ardic, Fatih Sivri, Abdullah Eren Cetin, Elif Tunc, Hilmi Erdem Sumbul, Durmus Yıldıray Sahin, Mevlut Koc","doi":"10.1007/s00380-025-02578-8","DOIUrl":"https://doi.org/10.1007/s00380-025-02578-8","url":null,"abstract":"Although surface electrocardiography (ECG) provides important information about the localization of atrial flutter (Afl), in cases where the p wave is unclear, it may not provide enough information about the ablation strategy and the procedure time may be prolonged. This study aimed to investigate the potential utility of crista terminalis double split signals in the differentiation of right- versus left-sided Afl in patients undergoing ablation therapy. In this retrospective study, symptomatic patients with Afl diagnosed by surface ECG and in whom no thrombus was detected by transesophageal echocardiography were enrolled. The decapolar catheter was placed into the crista terminalis and coronary sinus. The two most distant split signals were recorded as 'maximum interdeflection time' (MIT) in crista terminalis. The right or left atrium was mapped with 3-D system. 3-D mapping identified 112 patients with right Afl and 32 patients with left Afl. The right atrium was found to be significantly increased in patients with right Afl, whereas the left atrial diameter (LAD) was found to be significantly increased in patients with left Afl. The number of patients with coronary sinus activation sequence from proximal to distal, coronary sinus proximal to distal interval time and MIT were significantly increased in patients with right Afl. When patients with MIT > 80 ms and coronary sinus activation sequence from proximal to distal were taken together, it was found that the distinction between right and left atrial flutter was perfectly distinguished. In conclusion, MIT may serve as a valuable adjunctive parameter for distinguishing right- from left-sided Afl prior to 3-D mapping.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144659102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to the comments regarding "Overnight stiffness index from finger photoplethysmography in relation to markers of cardiovascular risk and vascular ageing". 回复关于“手指光体积脉搏图显示的夜间僵硬指数与心血管风险和血管老化标志物的关系”的评论。

IF 1.4 4区医学

Heart and Vessels Pub Date : 2025-07-18 DOI: 10.1007/s00380-025-02582-y

Henrik Hellqvist, Thomas Kahan, Jonas Spaak

引用次数: 0

When should bepridil concomitant with catheter ablation for persistent atrial fibrillation be discontinued? The importance of left atrial reverse remodeling. 贝普利地尔联合导管消融治疗持续性房颤何时应停用？左心房反向重构的重要性。

IF 1.4 4区医学

Heart and Vessels Pub Date : 2025-07-18 DOI: 10.1007/s00380-025-02579-7

Yuki Hasegawa, Rie Akagawa, Naomasa Suzuki, Yasuhiro Ikami, Sou Otsuki, Akiko Sanada, Shinsuke Okada, Hirotaka Sugiura, Masaomi Chinushi, Takayuki Inomata

{"title":"When should bepridil concomitant with catheter ablation for persistent atrial fibrillation be discontinued? The importance of left atrial reverse remodeling.","authors":"Yuki Hasegawa, Rie Akagawa, Naomasa Suzuki, Yasuhiro Ikami, Sou Otsuki, Akiko Sanada, Shinsuke Okada, Hirotaka Sugiura, Masaomi Chinushi, Takayuki Inomata","doi":"10.1007/s00380-025-02579-7","DOIUrl":"https://doi.org/10.1007/s00380-025-02579-7","url":null,"abstract":"Bepridil are often administered after catheter ablation (CA) in patients with persistent atrial fibrillation (AF); however, it is unclear for how long it should be continued. We administered hybrid therapy consisting of CA and bepridil to 130 patients with persistent AF and left atrial (LA) enlargement (volume index > 48 ml/m2). After 2 months of hybrid therapy, bepridil discontinuation was attempted. All patients underwent echocardiography 6 months after CA. We investigated the relationship between the duration of bepridil administration and the recurrence of AF after bepridil discontinuation. After excluding patients who were unable to maintain sinus rhythm during bepridil administration (n = 18), and those who disagreed to bepridil discontinuation (n = 17), 95 patients were divided into the short-term continuation (bepridil discontinued for < 6 months [median 3 months] after CA [n = 63]), and long-term continuation (bepridil discontinued for > 6 months [median 11.4 months] after CA [n = 32]) groups. During the mean follow-up period of 28 ± 15 months, the groups showed a similar incidence of recurrent AF after bepridil discontinuation. In the long-term continuation group, 13 patients had recurrence, with 8 (62%) cases occurring within 4 months after discontinuation. A multivariate Cox regression analysis revealed that left atrial (LA) reverse remodeling (> 15% decrease in LA volume index at 6 months) was an independent predictor of recurrent AF after CA (p < 0.01). Long-term bepridil administration after CA did not affect the recurrence of AF after discontinuation. The assessment of LA reverse remodeling may be useful for decision-making regarding the discontinuation of antiarrhythmic drugs after CA.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of pericoronary adipose tissue attenuation and coronary microvascular dysfunction on cardiac remodeling and dysfunction. 冠状动脉周围脂肪组织衰减和冠状动脉微血管功能障碍对心脏重构和功能障碍的影响。

IF 1.4 4区医学

Heart and Vessels Pub Date : 2025-07-14 DOI: 10.1007/s00380-025-02576-w

Mai Katsura, Yu Horiuchi, Daiki Yoshiura, Kazuyuki Yahagi, Yuki Gonda, Masahiko Asami, Masanori Taniwaki, Kota Komiyama, Hitomi Yuzawa, Jun Tanaka, Kengo Tanabe

{"title":"Impact of pericoronary adipose tissue attenuation and coronary microvascular dysfunction on cardiac remodeling and dysfunction.","authors":"Mai Katsura, Yu Horiuchi, Daiki Yoshiura, Kazuyuki Yahagi, Yuki Gonda, Masahiko Asami, Masanori Taniwaki, Kota Komiyama, Hitomi Yuzawa, Jun Tanaka, Kengo Tanabe","doi":"10.1007/s00380-025-02576-w","DOIUrl":"https://doi.org/10.1007/s00380-025-02576-w","url":null,"abstract":"We aimed to examine the impact of coronary inflammation, coronary microvascular dysfunction (CMD), and coronary artery spasm (CAS) on cardiac remodeling and dysfunction in patients suspected of angina with non-obstructive coronary artery disease (ANOCA). This retrospective single-center study included consecutive patients who underwent coronary spasm provocation testing between July 2020 and January 2025 for suspected ANOCA without prior revascularization and coronary stenosis ≥ 75%. Those who underwent coronary angiography after September 2022 also underwent invasive coronary physiology studies to diagnose structural CMD. PCAT attenuation (PCATA), reflecting coronary inflammation, was measured from prior coronary CT angiography, while strain analyses were obtained from prior echocardiography. Regression models were established between echocardiographic parameters and each of PCATA, CMD, and CAS. 257 patients (mean age, 64.2 ± 12.2 years; male, 62.1%) were included in the analysis. Multivariable regression analyses including PCATA, CMD, and CAS demonstrated that higher PCATA was associated with higher left ventricular mass index (β = 0.25, p = 0.007), reduced left ventricular ejection fraction (β = -0.21, p = 0.01), and impaired right ventricular four-chamber strain (β = 0.21, p = 0.04). CMD was independently associated with higher left atrial volume index (β = 0.67, p = 0.002) and impaired left atrial contraction strain (β = 5.31, p = 0.009). CAS showed no correlation with these parameters. Our study demonstrated a significant association between PCATA and left ventricular remodeling and dysfunction independent of CMD. It also revealed a direct relationship between CMD and left atrial remodeling and dysfunction.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0