Heart and Vessels最新文献_第6页

Reconsidering the association between transcatheter tricuspid valve repair and sympathetic activity. 重新考虑经导管三尖瓣修复与交感神经活动的关系。

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-20 DOI: 10.1007/s00380-026-02746-4

Maryam Imran Sheikh, Zain Ul Abideen

引用次数: 0

Response to the letter to the editor: sympathetic overactivation in patients undergoing transcatheter tricuspid valve repair. 对编辑的回复：接受经导管三尖瓣修复的患者交感神经过度激活。

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-20 DOI: 10.1007/s00380-026-02745-5

Dominik Nelles, Can Öztürk, Christoph Hammerstingl

引用次数: 0

Real-world clinical outcomes after cardiac resynchronization therapy in cardiac sarcoidosis. 心脏结节病心脏再同步化治疗后的实际临床结果。

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-19 DOI: 10.1007/s00380-026-02751-7

Yoshiyasu Aizawa, Kenji Yodogawa, Shuhei Okajima, Nobuaki Ito, Rei Mimuro, Masato Hachisuka, Yuhi Fujimoto, Yukichi Tokita, Tomoko S Kato, Wataru Shimizu, Kuniya Asai, Yu-Ki Iwasaki

{"title":"Real-world clinical outcomes after cardiac resynchronization therapy in cardiac sarcoidosis.","authors":"Yoshiyasu Aizawa, Kenji Yodogawa, Shuhei Okajima, Nobuaki Ito, Rei Mimuro, Masato Hachisuka, Yuhi Fujimoto, Yukichi Tokita, Tomoko S Kato, Wataru Shimizu, Kuniya Asai, Yu-Ki Iwasaki","doi":"10.1007/s00380-026-02751-7","DOIUrl":"10.1007/s00380-026-02751-7","url":null,"abstract":"Cardiac sarcoidosis (CS) is an inflammatory/granulomatous disease that affects the heart and is responsible for mortality due to fatal arrhythmias or systolic heart failure. The efficacy and outcomes of cardiac resynchronization therapy (CRT) for CS remain uncertain. We retrospectively analyzed a cohort of 108 patients diagnosed with CS at Nippon Medical School Hospital and extracted 19 patients who underwent CRT implantation between 2007 and 2024 (68% female, mean age 70 ± 8 years). The mean follow-up period was 6.7 ± 4.3 years. Of 19 patients with CRT devices (2 CRT-Ps and 17 CRT-Ds), 5 patients were upgraded from pacemakers and 5 from ICDs. At 6 months after device implantation, QRS duration shortened (172 ± 34 vs. 128 ± 27ms, p < 0.001), NYHA (2.6 ± 0.8 vs. 2.1 ± 1.0, p = 0.037) improved, and BiV pacing percentage was 98 ± 2%. However, LVESV (147 ± 74 vs. 155 ± 70 ml, p = 0.878) and LVEF (28 ± 9 vs. 28 ± 11%, p = 0.452) did not improve. During the follow-up period, 8 hospitalizations due to heart failure, 2 appropriate ICD shocks, and 6 deaths due to progressive heart failure were observed. Device-related complications developed in 4 patients. In this small retrospective cohort of patients with advanced cardiac sarcoidosis undergoing CRT implantation, echocardiographic reverse remodeling was limited despite improvements in QRS duration and NYHA functional class. Clinical outcomes remained poor, likely reflecting the advanced and heterogeneous nature of the underlying disease. Further comparative studies are warranted.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to "Acute heart failure and interleukin-6: Biomarker, bystander, or therapeutic target?" 急性心力衰竭与白细胞介素-6：生物标志物、旁观者还是治疗靶点？

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-19 DOI: 10.1007/s00380-026-02744-6

Makoto Kishihara, Yuichiro Minami, Hidetoshi Hattori, Shintaro Haruki, Junichi Yamaguchi

引用次数: 0

HFA-PEFF and H₂FPEF scores for cardiovascular risk stratification in patients with sick sinus syndrome. HFA-PEFF和H2FPEF评分对病窦综合征患者心血管危险分层的影响。

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-19 DOI: 10.1007/s00380-026-02750-8

Hironobu Sumiyoshi, Hidemori Hayashi, Akira Nakashima, Kenta Yoshida, Toshikazu Kono, Maki Ono, Akira Mizukami, Tohru Minamino, Hiroshi Tasaka

{"title":"HFA-PEFF and H2FPEF scores for cardiovascular risk stratification in patients with sick sinus syndrome.","authors":"Hironobu Sumiyoshi, Hidemori Hayashi, Akira Nakashima, Kenta Yoshida, Toshikazu Kono, Maki Ono, Akira Mizukami, Tohru Minamino, Hiroshi Tasaka","doi":"10.1007/s00380-026-02750-8","DOIUrl":"https://doi.org/10.1007/s00380-026-02750-8","url":null,"abstract":"The HFA-PEFF and H2FPEF scores were developed to aid in the diagnosis of heart failure with preserved ejection fraction (HFpEF) and have demonstrated prognostic value. Although sick sinus syndrome (SSS) is closely associated with both atrial fibrillation (AF) and HFpEF, the prognostic utility of these scores in patients with SSS remains unknown. This multicenter observational study included 206 patients with SSS and preserved left ventricular ejection fraction who underwent dual-chamber pacemaker implantation. HFA-PEFF and H2FPEF scores were calculated using baseline clinical and echocardiographic data. The primary endpoint was a composite of heart failure hospitalization, ischemic stroke, and cardiovascular death. The secondary endpoint was persistent AF lasting ≥ 7 days. Over a median follow-up of 36 months, 35 patients experienced the primary endpoint and 45 developed persistent AF. Kaplan-Meier analysis showed that patients with higher HFA-PEFF scores had a significantly increased risk of both the primary endpoint and persistent AF. In multivariable Cox regression analysis, the HFA-PEFF score remained independently associated with the primary endpoint and persistent AF after adjustment for clinically relevant covariates. In contrast, the H2FPEF score was not independently associated with the primary endpoint. Similar findings were observed when the analysis was restricted to patients without a history of paroxysmal AF. The HFA-PEFF score may be a useful tool for cardiovascular risk stratification and prediction of persistent AF in patients with SSS and preserved ejection fraction after pacemaker implantation.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic implications of a four-group classification based on estimated plasma volume status and creatinine in acute heart failure. 基于估计血浆容量状态和肌酐的急性心力衰竭四组分类的预后意义。

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-19 DOI: 10.1007/s00380-026-02748-2

Ran Sumida, Daisuke Kitano, Saki Mizobuchi, Masatsugu Miyagawa, Yutaka Koyama, Hidesato Fujito, Riku Arai, Takumi Hatta, Keisuke Kojima, Yuki Saito, Kazuto Toyama, Yasuo Okumura

{"title":"Prognostic implications of a four-group classification based on estimated plasma volume status and creatinine in acute heart failure.","authors":"Ran Sumida, Daisuke Kitano, Saki Mizobuchi, Masatsugu Miyagawa, Yutaka Koyama, Hidesato Fujito, Riku Arai, Takumi Hatta, Keisuke Kojima, Yuki Saito, Kazuto Toyama, Yasuo Okumura","doi":"10.1007/s00380-026-02748-2","DOIUrl":"https://doi.org/10.1007/s00380-026-02748-2","url":null,"abstract":"We evaluated the prognostic value of a four-group classification combining estimated plasma volume status (ePVS) and serum creatinine (Cre) in patients hospitalized for acute decompensated heart failure (ADHF). We analyzed 914 patients from the SAKURA HF Registry-2 enrolled between September 2018 and December 2023. At discharge, patients were stratified into four groups using ePVS (cutoff, 5.5 mL/g) and Cre (cutoff, 1.1 mg/dL): low-ePVS/low-Cre (n = 285), high-ePVS/low-Cre (n = 136), low-ePVS/high-Cre (n = 263), and high-ePVS/high-Cre (n = 230). The primary endpoint was a composite of all-cause mortality or heart failure rehospitalization. Multivariable Cox models were adjusted for clinical, laboratory, echocardiographic, and discharge-medication covariates. Median age was 74 years and 68% were men. Over a median follow-up of 368 days (interquartile range [IQR], 89-548), 349 patients (38.2%) experienced the primary endpoint, with significant differences among groups (log-rank p < 0.001). In multivariable models, compared with low-ePVS/low-Cre, risk was higher in high-ePVS/low-Cre (hazard ratio [HR] 2.38, 95% confidence interval [CI] 1.31-4.30; p = 0.004) and high-ePVS/high-Cre (HR 1.98, 95% CI 1.12-3.48; p = 0.018), but not in low-ePVS/high-Cre (HR 1.62, 95% CI 0.94-2.79; p = 0.08). A discharge-based ePVS-Cre classification provided clinically relevant risk stratification after ADHF. Elevated ePVS despite non-elevated serum creatinine independently predicted adverse outcomes. When ePVS was low, the excess risk associated with elevated creatinine was attenuated after adjustment, whereas concomitant elevation of ePVS and creatinine remained a high-risk category. This simple bedside framework may support discharge risk assessment.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the editor: unaddressed research gaps in antithrombotic therapy following drug-coated balloon angioplasty for peripheral artery disease. 致编辑的信：外周动脉疾病药物包被球囊血管成形术后抗血栓治疗的研究空白尚未解决。

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-19 DOI: 10.1007/s00380-026-02755-3

Abdul Rehman Khan

引用次数: 0

Authors' reply: Risk stratification and determinants of cardiac recovery in hemodialysis patients with reduced ejection fraction. 作者回复：射血分数降低的血液透析患者心脏恢复的危险分层和决定因素。

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-19 DOI: 10.1007/s00380-026-02752-6

Toshikazu Kashiyama

引用次数: 0

Impact of atrial fibrillation on heart failure-related events after endovascular therapy for peripheral artery disease. 心房颤动对外周动脉疾病血管内治疗后心力衰竭相关事件的影响

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-19 DOI: 10.1007/s00380-026-02749-1

Yuki Shima, Eiji Karashima, Shingo Kurimoto, Takashi Shimonaga, Tomohiro Yoshino, Hironobu Toda, Kohei Kawamura, Akira Takashima, Yoji Urabe, Yasunori Arai, Yusuke Kobayashi, Takanobu Okazaki, Naoto Ohsawa, Gakuto Bando, Narumi Irie, Kazunori Mushiake, Naoya Inoue, Mitsuru Abe

{"title":"Impact of atrial fibrillation on heart failure-related events after endovascular therapy for peripheral artery disease.","authors":"Yuki Shima, Eiji Karashima, Shingo Kurimoto, Takashi Shimonaga, Tomohiro Yoshino, Hironobu Toda, Kohei Kawamura, Akira Takashima, Yoji Urabe, Yasunori Arai, Yusuke Kobayashi, Takanobu Okazaki, Naoto Ohsawa, Gakuto Bando, Narumi Irie, Kazunori Mushiake, Naoya Inoue, Mitsuru Abe","doi":"10.1007/s00380-026-02749-1","DOIUrl":"https://doi.org/10.1007/s00380-026-02749-1","url":null,"abstract":"Atrial fibrillation (AF) is common in patients with peripheral artery disease (PAD) and is associated with adverse cardiovascular outcomes. However, its impact on heart failure (HF)-related events after endovascular therapy (EVT) remains unclear, particularly according to baseline HF status.We retrospectively analyzed a multicenter cohort of 1585 patients with symptomatic PAD undergoing EVT. Patients were stratified according to AF and baseline HF status. The primary outcome was HF-related events over a 3-year follow-up period. Kaplan-Meier analysis and Cox proportional hazards models were used. AF was associated with a higher risk of HF-related events. At 3 years, event-free survival was lower in patients with AF than in those without AF. In patients without baseline HF, event-free survival was significantly lower in those with AF (87.9 vs. 96.8%, log-rank p < 0.001). In contrast, in patients with established HF, the difference was attenuated (67.2 vs. 75.7%, log-rank p = 0.053). In stratified multivariable analysis, AF was strongly associated with HF-related events in patients without baseline HF (HR 4.03, 95% CI 1.85-8.78; p < 0.001), whereas this association was attenuated in those with baseline HF (HR 1.34, 95% CI 0.96-1.88; p = 0.085). A significant interaction was observed between AF and baseline HF status (p for interaction = 0.013). In patients with PAD undergoing EVT, AF was associated with HF-related events; however, its prognostic impact was significantly modified by baseline HF status, with a markedly stronger effect observed in patients without pre-existing HF.","PeriodicalId":12940,"journal":{"name":"Heart and Vessels","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute heart failure and interleukin-6: Biomarker, bystander, or therapeutic target? 急性心力衰竭与白细胞介素-6：生物标志物、旁观者还是治疗靶点？

IF 1.5 4区医学

Heart and Vessels Pub Date : 2026-08-19 DOI: 10.1007/s00380-026-02743-7

Xiaoxia Xiao

引用次数: 0