有氧运动习惯与较高的白蛋白-球蛋白比率和较低的细胞免疫-炎症标志物的关联：有氧运动对动脉粥样硬化性心血管疾病的预防作用的含义

IF 1.5 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Heart and Vessels Pub Date : 2025-07-19 DOI:10.1007/s00380-025-02585-9

Leiying Zhang

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引用次数: 0

摘要

这一通信确定了Tani等人的文章（Heart vessel . 2025;40:509-522）中不可调和的矛盾，这些矛盾严重地破坏了其结论。关键问题包括吸烟与白蛋白-球蛋白比（AGR）之间的矛盾关系、不一致的肝酶模式和不一致的炎症标志物反应。涉及体液抑制和肝脏适应的其他机制更好地解释了这一发现。该研究的横断面设计不能解决这些差异，需要在临床解释之前进行纵向验证。

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Association of aerobic exercise habits with higher albumin-globulin ratio and lower cellular immune-inflammatory markers: implication of the preventive effect of aerobic exercise on atherosclerotic cardiovascular disease.

This correspondence identifies irreconcilable contradictions in Tani et al.'s article (Heart Vessels. 2025;40:509-522) that critically undermine its conclusions. Key concerns include paradoxical relationships between smoking and albumin-globulin ratio (AGR), discordant liver enzyme patterns, and inconsistent inflammatory marker responses. Alternative mechanisms involving humoral suppression and hepatic adaptation better explain the findings. The study's cross-sectional design cannot resolve these discrepancies, necessitating longitudinal validation before clinical interpretation.

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来源期刊

Heart and Vessels 医学-外周血管病

CiteScore

3.10

自引率

13.30%

发文量

211

审稿时长

2 months

期刊介绍： Heart and Vessels is an English-language journal that provides a forum of original ideas, excellent methods, and fascinating techniques on cardiovascular disease fields. All papers submitted for publication are evaluated only with regard to scientific quality and relevance to the heart and vessels. Contributions from those engaged in practical medicine, as well as from those involved in basic research, are welcomed.